A biomaterial-assisted mesenchymal stromal cell therapy alleviates colonic radiation-induced damage

Biomaterials

Volumn 115, Issue , 2017, Pages 40-52

  Moussa, Lara ^a,b,c   Pattappa, Girish ^b,c   Doix, Bastien ^a   Benselama, Sarra Louiza ^a   Demarquay, Christelle ^a   Benderitter, Marc ^a   Sémont, Alexandra ^a   Tamarat, Radia ^a   Guicheux, Jérôme ^b,c,d   Weiss, Pierre ^b,c,d   Réthoré, Gildas ^b,c,d   Mathieu, Noëlle ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE NANTES   (France)

^d NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

Colonic permeability; Colorectal irradiation; Hydrogel; Injection through colonoscopy; Mesenchymal stromal cells; Regenerative medicine

Indexed keywords

BIOMATERIALS; CELLS; CYTOLOGY; ENDOSCOPY; FLOWCHARTING; HYDROGELS; MACROPHAGES; SILICON; TISSUE;

COLONOSCOPY; HYDROXY PROPYL METHYL CELLULOSE; MACROPHAGE INFILTRATIONS; MESENCHYMAL STROMAL CELLS; RADIATION INDUCED DAMAGE; REGENERATIVE MEDICINE; SYSTEMIC ADMINISTRATION; THERAPEUTIC BENEFITS;

CELL CULTURE;

BIOMATERIAL; CD68 ANTIGEN; CLAUDIN 4; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HYDROXYPROPYLMETHYLCELLULOSE; INTERLEUKIN 10; INTERLEUKIN 11; KERATINOCYTE GROWTH FACTOR; PROSTAGLANDIN E2; SOMATOMEDIN B; SOMATOMEDIN C; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL STRUCTURE; CELL THERAPY; COLON INJURY; COLONOSCOPE; COLONOSCOPY; CONTROLLED STUDY; ENGRAFTMENT; HYDROGEL; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA PERMEABILITY; MACROPHAGE; MALE; MESENCHYMAL STROMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION INJURY; RAT; SHEAR RATE; THERAPY EFFECT; VISCOSITY; YOUNG MODULUS; ANIMAL; CELL CULTURE; CHEMISTRY; COLON DISEASE; CONFORMAL RADIOTHERAPY; CYTOLOGY; MESENCHYMAL STEM CELL TRANSPLANTATION; PATHOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; TISSUE SCAFFOLD; TRANSGENIC RAT; TREATMENT OUTCOME;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; COLONIC DISEASES; HYDROGELS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; RADIATION INJURIES; RADIOTHERAPY, CONFORMAL; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; TISSUE SCAFFOLDS; TREATMENT OUTCOME;

EID: 84996938723     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.11.017     Document Type: Article

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