Familial occurrence of pulmonary embolism after intravenous, adipose tissue-derived stem cell therapy

Yonsei Medical Journal

Volumn 54, Issue 5, 2013, Pages 1293-1296

  Jung, Jae Woo ^a   Kwon, Minsuk ^a   Choi, Jae Chol ^a   Shin, Jong Wook ^a   Park, In Won ^a   Choi, Byoung Whui ^a   Kim, Jae Yeol ^a  

^a Chung Ang University College of Medicine   (South Korea)

Author keywords

Family; Infarct; Pulmonary embolism; Stem cell

Indexed keywords

ANTICOAGULANT AGENT; D DIMER; ENOXAPARIN; WARFARIN;

ADIPOSE TISSUE; ADULT; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DRUG WITHDRAWAL; FAMILIAL DISEASE; FOLLOW UP; HEMATURIA; HUMAN; INTERVERTEBRAL DISK HERNIA; LUNG EMBOLISM; LUNG INFARCTION; MALE; PLEURA EFFUSION; STEM CELL TRANSPLANTATION;

FAMILY; INFARCT; PULMONARY EMBOLISM; STEM CELL;

ADIPOSE TISSUE; ADULT; CELL- AND TISSUE-BASED THERAPY; FEMALE; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; PULMONARY EMBOLISM; PULMONARY INFARCTION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84880995262     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2013.54.5.1293     Document Type: Article

References (13)

1. Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature 2012;481:295-305.
2. Shen JF, Sugawara A, Yamashita J, Ogura H, Sato S. Dedifferentiated fat cells: an alternative source of adult multipotent cells from the adipose tissues. Int J Oral Sci 2011;3:117-24.
3. Sensebé L, Bourin P. Mesenchymal stem cells for therapeutic purposes. Transplantation 2009;87(9 Suppl):S49-53.
4. Parker AM, Katz AJ. Adipose-derived stem cells for the regeneration of damaged tissues. Expert Opin Biol Ther 2006;6:567-78.
5. Brignier AC, Gewirtz AM. Embryonic and adult stem cell therapy. J Allergy Clin Immunol 2010;125(2 Suppl 2):S336-44.
6. Erickson GR, Gimble JM, Franklin DM, Rice HE, Awad H, Guilak F. Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo. Biochem Biophys Res Commun 2002; 290:763-9.
7. Winter A, Breit S, Parsch D, Benz K, Steck E, Hauner H, et al. Cartilage-like gene expression in differentiated human stem cell spheroids: a comparison of bone marrow-derived and adipose tissue-derived stromal cells. Arthritis Rheum 2003;48:418-29.
8. Black LL, Gaynor J, Adams C, Dhupa S, Sams AE, Taylor R, et al. Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs. Vet Ther 2008;9: 192-200.
9. Black LL, Gaynor J, Gahring D, Adams C, Aron D, Harman S, et al. Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial. Vet Ther 2007;8:272-84.
10. Cyranoski D. Korean deaths spark inquiry. Nature 2010;468:485.
11. Takahashi Y, Tsuji O, Kumagai G, Hara CM, Okano HJ, Miyawaki A, et al. Comparative study of methods for administering neural stem/progenitor cells to treat spinal cord injury in mice. Cell Transplant 2011;20:727-39.
12. Furlani D, Ugurlucan M, Ong L, Bieback K, Pittermann E, Westien I, et al. Is the intravascular administration of mesenchymal stem cells safe? Mesenchymal stem cells and intravital microscopy. Microvasc Res 2009;77:370-6.
13. Tatsumi K, Ohashi K, Matsubara Y, Kohori A, Ohno T, Kakidachi H, et al. Tissue factor triggers procoagulation in transplanted mesenchymal stem cells leading to thromboembolism. Biochem Biophys Res Commun 2013;431:203-9.