메뉴 건너뛰기




Volumn 66, Issue 2, 2006, Pages 552-559

Orazipone, a locally acting immunomodulator, ameliorates intestinal radiation injury: A preclinical study in a novel rat model

Author keywords

Disaster planning; Immunomodulation; Intestines; Radiation injuries

Indexed keywords

BIOLOGICAL ORGANS; DOSIMETRY; HISTOLOGY; IMMUNOLOGY; ONCOLOGY; RADIOTHERAPY;

EID: 33748331265     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.05.067     Document Type: Article
Times cited : (15)

References (34)
  • 1
    • 11144356545 scopus 로고    scopus 로고
    • Perspectives on cancer therapy-induced mucosal injury: Pathogenesis, measurement, epidemiology, and consequences for patients
    • Sonis S.T., Elting L.S., Keefe D., et al. Perspectives on cancer therapy-induced mucosal injury: Pathogenesis, measurement, epidemiology, and consequences for patients. Cancer 100 (2004) 1995-2025
    • (2004) Cancer , vol.100 , pp. 1995-2025
    • Sonis, S.T.1    Elting, L.S.2    Keefe, D.3
  • 2
    • 22644439345 scopus 로고    scopus 로고
    • Gastrointestinal complications of pelvic radiotherapy: Are they of any importance?
    • Andreyev J. Gastrointestinal complications of pelvic radiotherapy: Are they of any importance?. Gut 54 (2005) 1051-1054
    • (2005) Gut , vol.54 , pp. 1051-1054
    • Andreyev, J.1
  • 3
    • 0042527679 scopus 로고    scopus 로고
    • Bowel injury: Current and evolving management strategies
    • Hauer-Jensen M., Wang J., and Denham J.W. Bowel injury: Current and evolving management strategies. Semin Radiat Oncol 13 (2003) 357-371
    • (2003) Semin Radiat Oncol , vol.13 , pp. 357-371
    • Hauer-Jensen, M.1    Wang, J.2    Denham, J.W.3
  • 4
    • 0036283219 scopus 로고    scopus 로고
    • The radiotherapeutic injury-A complex "wound."
    • Denham J.W., and Hauer-Jensen M. The radiotherapeutic injury-A complex "wound.". Radiother Oncol 63 (2002) 129-145
    • (2002) Radiother Oncol , vol.63 , pp. 129-145
    • Denham, J.W.1    Hauer-Jensen, M.2
  • 6
    • 33748314806 scopus 로고    scopus 로고
    • A novel immunomodulating agent (OR-1384) ameliorates inflammation and tissue damage in dextran sulfate model of mouse colitis [Abstract]
    • May 10-16
    • Murthy S., Murthy N.S., Coppola D., et al. A novel immunomodulating agent (OR-1384) ameliorates inflammation and tissue damage in dextran sulfate model of mouse colitis [Abstract]. Annual Meeting of American Gastroenterological Association (1997) May 10-16
    • (1997) Annual Meeting of American Gastroenterological Association
    • Murthy, S.1    Murthy, N.S.2    Coppola, D.3
  • 7
    • 33748294476 scopus 로고    scopus 로고
    • OR-1384, a novel locally acting immunomodulating agent, protects against experimental colitis [Abstract]
    • May 10-16
    • Aho P., Koponen A., Haasio K., et al. OR-1384, a novel locally acting immunomodulating agent, protects against experimental colitis [Abstract]. Annual Meeting of American Gastroenterological Association (1997) May 10-16
    • (1997) Annual Meeting of American Gastroenterological Association
    • Aho, P.1    Koponen, A.2    Haasio, K.3
  • 8
    • 33748296380 scopus 로고    scopus 로고
    • Interleukin-8 induced neutrophil activation is suppressed by the thiol modulating anti-colitis agent OR-1384 [Abstract]
    • May 18-24
    • Nissinen E., Kaivola J., and Linden I.B. Interleukin-8 induced neutrophil activation is suppressed by the thiol modulating anti-colitis agent OR-1384 [Abstract]. Annual Meeting of American Gastroenterological Association (1996) May 18-24
    • (1996) Annual Meeting of American Gastroenterological Association
    • Nissinen, E.1    Kaivola, J.2    Linden, I.B.3
  • 9
    • 0024997507 scopus 로고
    • Late radiation injury of the small intestine. Clinical, pathophysiologic, and radiobiologic aspects
    • Hauer-Jensen M. Late radiation injury of the small intestine. Clinical, pathophysiologic, and radiobiologic aspects. Acta Oncol 29 (1990) 401-415
    • (1990) Acta Oncol , vol.29 , pp. 401-415
    • Hauer-Jensen, M.1
  • 10
    • 0023810878 scopus 로고
    • Effects of accelerated fractionation on radiation injury of the small intestine: A new rat model
    • Hauer-Jensen M., Poulakos L., and Osborne J.W. Effects of accelerated fractionation on radiation injury of the small intestine: A new rat model. Int J Radiat Oncol Biol Phys 14 (1988) 1205-1212
    • (1988) Int J Radiat Oncol Biol Phys , vol.14 , pp. 1205-1212
    • Hauer-Jensen, M.1    Poulakos, L.2    Osborne, J.W.3
  • 11
    • 84907105766 scopus 로고
    • Late changes following single dose roentgen irradiation of rat small intestine
    • Hauer-Jensen M., Sauer T., Devik F., et al. Late changes following single dose roentgen irradiation of rat small intestine. Acta Radiol Oncol 22 (1983) 299-303
    • (1983) Acta Radiol Oncol , vol.22 , pp. 299-303
    • Hauer-Jensen, M.1    Sauer, T.2    Devik, F.3
  • 12
    • 0027058679 scopus 로고
    • Tolerance of rat small intestine to localized single dose and fractionated irradiation
    • Langberg C.W., Sauer T., Reitan J.B., et al. Tolerance of rat small intestine to localized single dose and fractionated irradiation. Acta Oncol 31 (1992) 781-787
    • (1992) Acta Oncol , vol.31 , pp. 781-787
    • Langberg, C.W.1    Sauer, T.2    Reitan, J.B.3
  • 13
    • 84985234195 scopus 로고
    • Estimation of surface area from vertical sections
    • Baddeley A.J., Gundersen H.J.G., and Cruz-Orive L.M. Estimation of surface area from vertical sections. J Microsc 142 (1986) 259-276
    • (1986) J Microsc , vol.142 , pp. 259-276
    • Baddeley, A.J.1    Gundersen, H.J.G.2    Cruz-Orive, L.M.3
  • 14
    • 0029919474 scopus 로고    scopus 로고
    • Relationship between intestinal fibrosis and histopathologic and morphometric changes in consequential and late radiation enteropathy
    • Langberg C.W., Sauer T., Reitan J.B., et al. Relationship between intestinal fibrosis and histopathologic and morphometric changes in consequential and late radiation enteropathy. Acta Oncol 35 (1996) 81-87
    • (1996) Acta Oncol , vol.35 , pp. 81-87
    • Langberg, C.W.1    Sauer, T.2    Reitan, J.B.3
  • 15
    • 0030774734 scopus 로고    scopus 로고
    • Increased transforming growth factor beta (TGF-beta) immunoreactivity is independently associated with chronic injury in both consequential and primary radiation enteropathy
    • Richter K.K., Langberg C.W., Sung C.C., et al. Increased transforming growth factor beta (TGF-beta) immunoreactivity is independently associated with chronic injury in both consequential and primary radiation enteropathy. Int J Radiat Oncol Biol Phys 39 (1997) 187-195
    • (1997) Int J Radiat Oncol Biol Phys , vol.39 , pp. 187-195
    • Richter, K.K.1    Langberg, C.W.2    Sung, C.C.3
  • 16
    • 0031737426 scopus 로고    scopus 로고
    • Cellular sources of transforming growth factor-beta isoforms in early and chronic radiation enteropathy
    • Wang J., Zheng H., Sung C.C., et al. Cellular sources of transforming growth factor-beta isoforms in early and chronic radiation enteropathy. Am J Pathol 153 (1998) 1531-1540
    • (1998) Am J Pathol , vol.153 , pp. 1531-1540
    • Wang, J.1    Zheng, H.2    Sung, C.C.3
  • 17
    • 0034320191 scopus 로고    scopus 로고
    • Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice
    • Zheng H., Wang J., Koteliansky V.E., et al. Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice. Gastroenterology 119 (2000) 1286-1296
    • (2000) Gastroenterology , vol.119 , pp. 1286-1296
    • Zheng, H.1    Wang, J.2    Koteliansky, V.E.3
  • 18
    • 0025139442 scopus 로고
    • Nonuniform irradiation of the canine intestine. I. Effects
    • Vigneulle R.M., Herrera J., Gage T., et al. Nonuniform irradiation of the canine intestine. I. Effects. Radiat Res 121 (1990) 46-53
    • (1990) Radiat Res , vol.121 , pp. 46-53
    • Vigneulle, R.M.1    Herrera, J.2    Gage, T.3
  • 19
    • 0037388787 scopus 로고    scopus 로고
    • Effect of glicentin on gut mucosal growth in rats with jejunal and ileal Thiry-Vella fistulas
    • Hashimoto N., Ohyanagi H., and Kazuyuki S. Effect of glicentin on gut mucosal growth in rats with jejunal and ileal Thiry-Vella fistulas. J Pediatr Surg 38 (2003) 579-584
    • (2003) J Pediatr Surg , vol.38 , pp. 579-584
    • Hashimoto, N.1    Ohyanagi, H.2    Kazuyuki, S.3
  • 20
    • 10344247644 scopus 로고    scopus 로고
    • Novel sulfhydryl-reactive compounds orazipone and OR-1958 inhibit cytokine production and histamine release in rat and human mast cells
    • Vendelin J., Laitinen C., Vainio P.J., et al. Novel sulfhydryl-reactive compounds orazipone and OR-1958 inhibit cytokine production and histamine release in rat and human mast cells. Int Immunopharmacol 5 (2005) 177-184
    • (2005) Int Immunopharmacol , vol.5 , pp. 177-184
    • Vendelin, J.1    Laitinen, C.2    Vainio, P.J.3
  • 21
    • 33748293116 scopus 로고
    • Protection in acute and chronic colitis models by the sulhydryl modulating compound OR-1364 [Abstract]
    • May 9-15
    • Linden I.B., Aho P., Nissinen E., et al. Protection in acute and chronic colitis models by the sulhydryl modulating compound OR-1364 [Abstract]. American Gastroenterological Association (1992) May 9-15
    • (1992) American Gastroenterological Association
    • Linden, I.B.1    Aho, P.2    Nissinen, E.3
  • 22
    • 33748306350 scopus 로고
    • Protection against immune complex-induced colitis in rabbits by OR-1364 [Abstract]
    • June 25-29
    • Aho P., Koponen A., Haasio K., et al. Protection against immune complex-induced colitis in rabbits by OR-1364 [Abstract]. United European Gastroenterology Week (1994) June 25-29
    • (1994) United European Gastroenterology Week
    • Aho, P.1    Koponen, A.2    Haasio, K.3
  • 23
    • 33748297757 scopus 로고
    • The sulhydryl modulating compound OR-1364 protects against free radical induced colitis in rats [Abstract]
    • May 15-19
    • Aho P., Nissinen E., Penttila K.E., et al. The sulhydryl modulating compound OR-1364 protects against free radical induced colitis in rats [Abstract]. American Gastroenterological Association (1993) May 15-19
    • (1993) American Gastroenterological Association
    • Aho, P.1    Nissinen, E.2    Penttila, K.E.3
  • 24
    • 0025366460 scopus 로고
    • Changes in the rate of crypt epithelial cell proliferation and mucosal morphology induced by a T-cell-mediated response in human small intestine
    • Ferreira R.C., Forsyth L.E., Richman P.I., et al. Changes in the rate of crypt epithelial cell proliferation and mucosal morphology induced by a T-cell-mediated response in human small intestine. Gastroenterology 98 (1990) 1255-1263
    • (1990) Gastroenterology , vol.98 , pp. 1255-1263
    • Ferreira, R.C.1    Forsyth, L.E.2    Richman, P.I.3
  • 25
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu G., Fang Y.Z., Yang S., et al. Glutathione metabolism and its implications for health. J Nutr 134 (2004) 489-492
    • (2004) J Nutr , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.Z.2    Yang, S.3
  • 26
    • 0034063379 scopus 로고    scopus 로고
    • Role of mast cells in early and delayed radiation injury in rat intestine
    • Zheng H., Wang J., and Hauer-Jensen M. Role of mast cells in early and delayed radiation injury in rat intestine. Radiat Res 153 (2000) 533-539
    • (2000) Radiat Res , vol.153 , pp. 533-539
    • Zheng, H.1    Wang, J.2    Hauer-Jensen, M.3
  • 27
    • 0031737426 scopus 로고    scopus 로고
    • Cellular sources of transforming growth factor-beta isoforms in early and chronic radiation enteropathy
    • Wang J., Zheng H., Sung C.C., et al. Cellular sources of transforming growth factor-beta isoforms in early and chronic radiation enteropathy. Am J Pathol 153 (1998) 1531-1540
    • (1998) Am J Pathol , vol.153 , pp. 1531-1540
    • Wang, J.1    Zheng, H.2    Sung, C.C.3
  • 28
    • 0025024112 scopus 로고
    • Transforming growth factor beta: A promoter of late connective tissue injury following radiotherapy?
    • Canney P.A., and Dean S. Transforming growth factor beta: A promoter of late connective tissue injury following radiotherapy?. Br J Radiol 63 (1990) 620-623
    • (1990) Br J Radiol , vol.63 , pp. 620-623
    • Canney, P.A.1    Dean, S.2
  • 29
    • 0034320191 scopus 로고    scopus 로고
    • Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice
    • Zheng H., Wang J., Koteliansky V.E., et al. Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice. Gastroenterology 119 (2000) 1286-1296
    • (2000) Gastroenterology , vol.119 , pp. 1286-1296
    • Zheng, H.1    Wang, J.2    Koteliansky, V.E.3
  • 30
    • 0029058925 scopus 로고
    • Cellular basis of radiation-induced fibrosis
    • Rodemann H.P., and Bamberg M. Cellular basis of radiation-induced fibrosis. Radiother Oncol 35 (1995) 83-90
    • (1995) Radiother Oncol , vol.35 , pp. 83-90
    • Rodemann, H.P.1    Bamberg, M.2
  • 31
    • 10644294704 scopus 로고    scopus 로고
    • Platelets: New players in the mucosal scenario of inflammatory bowel disease
    • Danese S., Scaldaferri F., Papa A., et al. Platelets: New players in the mucosal scenario of inflammatory bowel disease. Eur Rev Med Pharmacol Sci 8 (2004) 193-198
    • (2004) Eur Rev Med Pharmacol Sci , vol.8 , pp. 193-198
    • Danese, S.1    Scaldaferri, F.2    Papa, A.3
  • 32
    • 0027979726 scopus 로고
    • Ionizing radiation enhances platelet adhesion to the extracellular matrix of human endothelial cells by an increase in the release of von Willebrand factor
    • Verheij M., Dewit L.G.H., Boomgard M.N., et al. Ionizing radiation enhances platelet adhesion to the extracellular matrix of human endothelial cells by an increase in the release of von Willebrand factor. Radiat Res 137 (1994) 202-207
    • (1994) Radiat Res , vol.137 , pp. 202-207
    • Verheij, M.1    Dewit, L.G.H.2    Boomgard, M.N.3
  • 33
    • 0035424673 scopus 로고    scopus 로고
    • Radiation-induced glomerular thrombus formation and nephropathy are not prevented by the ADP receptor antagonist clopidogrel
    • te Poele J.A.M., van Kleef E.M., van der Wal A., et al. Radiation-induced glomerular thrombus formation and nephropathy are not prevented by the ADP receptor antagonist clopidogrel. Int J Radiat Oncol Biol Phys 50 (2001) 1332-1338
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 1332-1338
    • te Poele, J.A.M.1    van Kleef, E.M.2    van der Wal, A.3
  • 34
    • 0036149561 scopus 로고    scopus 로고
    • Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine
    • Wang J., Albertson C.M., Zheng H., et al. Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine. Thromb Haemost 87 (2002) 122-128
    • (2002) Thromb Haemost , vol.87 , pp. 122-128
    • Wang, J.1    Albertson, C.M.2    Zheng, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.