메뉴 건너뛰기




Volumn 8, Issue 10, 2016, Pages 2525-2537

Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

Author keywords

Adipose tissue; Aging; Autophagy; ER Stress; Inflammation

Indexed keywords

ENZYME INHIBITOR; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; THAPSIGARGIN;

EID: 84995546016     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.101083     Document Type: Article
Times cited : (80)

References (49)
  • 2
    • 84857126328 scopus 로고    scopus 로고
    • Impact of macrophage inflammatory protein-1a deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion
    • Kennedy A, Gruen ML, Gutierrez DA, Surmi BK, Orr JS, Webb CD, Hasty AH. Impact of macrophage inflammatory protein-1a deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion. PLoS One. 2012; 7:e31508. doi:10.1371/journal.pone.0031508
    • (2012) PLoS One , vol.7
    • Kennedy, A.1    Gruen, M.L.2    Gutierrez, D.A.3    Surmi, B.K.4    Orr, J.S.5    Webb, C.D.6    Hasty, A.H.7
  • 3
    • 41249098290 scopus 로고    scopus 로고
    • Aging up-regulates expression of inflammatory mediators in mouse adipose tissue
    • Wu D, Ren Z, Pae M, Guo W, Cui X, Merrill AH, Meydani SN. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J Immunol. 2007; 179:4829-39. doi: 10.4049/jimmunol.179.7.4829
    • (2007) J Immunol , vol.179 , pp. 4829-4839
    • Wu, D.1    Ren, Z.2    Pae, M.3    Guo, W.4    Cui, X.5    Merrill, A.H.6    Meydani, S.N.7
  • 5
    • 0035347211 scopus 로고    scopus 로고
    • Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women
    • DeNino WF, Tchernof A, Dionne IJ, Toth MJ, Ades PA, Sites CK, Poehlman ET. Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women. Diabetes Care. 2001; 24:925-32. doi: 10.2337/diacare.24.5.925
    • (2001) Diabetes Care , vol.24 , pp. 925-932
    • DeNino, W.F.1    Tchernof, A.2    Dionne, I.J.3    Toth, M.J.4    Ades, P.A.5    Sites, C.K.6    Poehlman, E.T.7
  • 7
    • 71849105519 scopus 로고    scopus 로고
    • Dexamethasone and the inflammatory response in explants of human omental adipose tissue
    • Fain JN, Cheema P, Madan AK, Tichansky DS. Dexamethasone and the inflammatory response in explants of human omental adipose tissue. Mol Cell Endocrinol. 2010; 315:292-98. doi: 10.1016/j.mce.2009.10.004
    • (2010) Mol Cell Endocrinol , vol.315 , pp. 292-298
    • Fain, J.N.1    Cheema, P.2    Madan, A.K.3    Tichansky, D.S.4
  • 10
    • 84855681355 scopus 로고    scopus 로고
    • Adipose tissue stem cells meet preadipocyte commitment: going back to the future
    • Cawthorn WP, Scheller EL, MacDougald OA. Adipose tissue stem cells meet preadipocyte commitment: going back to the future. J Lipid Res. 2012; 53:227-46. doi: 10.1194/jlr.R021089
    • (2012) J Lipid Res , vol.53 , pp. 227-246
    • Cawthorn, W.P.1    Scheller, E.L.2    MacDougald, O.A.3
  • 11
    • 84946550842 scopus 로고    scopus 로고
    • Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging
    • Ghosh AK, Garg SK, Mau T, O'Brien M, Liu J, Yung R. Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging. J Gerontol A Biol Sci Med Sci. 2015; 70:1320-29.
    • (2015) J Gerontol A Biol Sci Med Sci , vol.70 , pp. 1320-1329
    • Ghosh, A.K.1    Garg, S.K.2    Mau, T.3    O'Brien, M.4    Liu, J.5    Yung, R.6
  • 12
    • 84911390954 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress is involved in the connection between inflammation and autophagy in type 2 diabetes
    • Liu H, Cao MM, Wang Y, Li LC, Zhu LB, Xie GY, Li YB. Endoplasmic reticulum stress is involved in the connection between inflammation and autophagy in type 2 diabetes. Gen Comp Endocrinol. 2015; 210:124-29. doi: 10.1016/j.ygcen.2014.09.006
    • (2015) Gen Comp Endocrinol , vol.210 , pp. 124-129
    • Liu, H.1    Cao, M.M.2    Wang, Y.3    Li, L.C.4    Zhu, L.B.5    Xie, G.Y.6    Li, Y.B.7
  • 13
    • 84917728088 scopus 로고    scopus 로고
    • Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease
    • Hosomi S, Kaser A, Blumberg RS. Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease. Curr Opin Gastroenterol. 2015; 31:81-88. doi: 10.1097/MOG.0000000000000144
    • (2015) Curr Opin Gastroenterol , vol.31 , pp. 81-88
    • Hosomi, S.1    Kaser, A.2    Blumberg, R.S.3
  • 14
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet. 2009; 43:67-93. doi: 10.1146/annurev-genet-102808-114910
    • (2009) Annu Rev Genet , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 15
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • Yang L, Li P, Fu S, Calay ES, Hotamisligil GS. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab. 2010; 11:467-78. doi: 10.1016/j.cmet.2010.04.005
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 19
    • 77953531909 scopus 로고    scopus 로고
    • Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles
    • Masiero E, Sandri M. Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles. Autophagy. 2010; 6:307-09. doi: 10.4161/auto.6.2.11137
    • (2010) Autophagy , vol.6 , pp. 307-309
    • Masiero, E.1    Sandri, M.2
  • 21
    • 77953577017 scopus 로고    scopus 로고
    • mTOR's role in ageing: protein synthesis or autophagy?
    • Hands SL, Proud CG, Wyttenbach A. mTOR's role in ageing: protein synthesis or autophagy? Aging (Albany NY). 2009; 1:586-97. doi: 10.18632/aging.100070
    • (2009) Aging (Albany NY) , vol.1 , pp. 586-597
    • Hands, S.L.1    Proud, C.G.2    Wyttenbach, A.3
  • 24
    • 0028036212 scopus 로고
    • Effects of age and anatomic site on preadipocyte number in rat fat depots
    • Kirkland JL, Hollenberg CH, Kindler S, Gillon WS. Effects of age and anatomic site on preadipocyte number in rat fat depots. J Gerontol. 1994; 49:B31-35. doi: 10.1093/geronj/49.1.B31
    • (1994) J Gerontol , vol.49 , pp. B31-B35
    • Kirkland, J.L.1    Hollenberg, C.H.2    Kindler, S.3    Gillon, W.S.4
  • 25
    • 0023915796 scopus 로고
    • Influences of aging and dietary restriction on serum thymosin alpha 1 levels in mice
    • Weindruch R, Naylor PH, Goldstein AL, Walford RL. Influences of aging and dietary restriction on serum thymosin alpha 1 levels in mice. J Gerontol. 1988; 43:B40-42. doi: 10.1093/geronj/43.2.B40
    • (1988) J Gerontol , vol.43 , pp. B40-42
    • Weindruch, R.1    Naylor, P.H.2    Goldstein, A.L.3    Walford, R.L.4
  • 26
    • 32444435024 scopus 로고    scopus 로고
    • Caloric restriction and aging: controversial issues
    • Masoro EJ. Caloric restriction and aging: controversial issues. J Gerontol A Biol Sci Med Sci. 2006; 61:14-19. doi: 10.1093/gerona/61.1.14
    • (2006) J Gerontol A Biol Sci Med Sci , vol.61 , pp. 14-19
    • Masoro, E.J.1
  • 27
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Blüher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science. 2003; 299:572-74. doi: 10.1126/science.1078223
    • (2003) Science , vol.299 , pp. 572-574
    • Blüher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 33
    • 84901466488 scopus 로고    scopus 로고
    • The contribution of visceral fat to improved insulin signaling in Ames dwarf mice
    • Menon V, Zhi X, Hossain T, Bartke A, Spong A, Gesing A, Masternak MM. The contribution of visceral fat to improved insulin signaling in Ames dwarf mice. Aging Cell. 2014; 13:497-506. doi: 10.1111/acel.12201
    • (2014) Aging Cell , vol.13 , pp. 497-506
    • Menon, V.1    Zhi, X.2    Hossain, T.3    Bartke, A.4    Spong, A.5    Gesing, A.6    Masternak, M.M.7
  • 34
    • 22744450382 scopus 로고    scopus 로고
    • Toward a unified theory of caloric restriction and longevity regulation
    • Sinclair DA. Toward a unified theory of caloric restriction and longevity regulation. Mech Ageing Dev. 2005; 126:987-1002. doi: 10.1016/j.mad.2005.03.019
    • (2005) Mech Ageing Dev , vol.126 , pp. 987-1002
    • Sinclair, D.A.1
  • 36
    • 75049085555 scopus 로고    scopus 로고
    • Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise
    • Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol. 2010; 45:138-48. doi: 10.1016/j.exger.2009.11.002
    • (2010) Exp Gerontol , vol.45 , pp. 138-148
    • Wohlgemuth, S.E.1    Seo, A.Y.2    Marzetti, E.3    Lees, H.A.4    Leeuwenburgh, C.5
  • 39
    • 84940000737 scopus 로고    scopus 로고
    • Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts
    • Makino N, Oyama J, Maeda T, Koyanagi M, Higuchi Y, Tsuchida K. Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts. Mol Cell Biochem. 2015; 403:1-11. doi: 10.1007/s11010-015-2327-0
    • (2015) Mol Cell Biochem , vol.403 , pp. 1-11
    • Makino, N.1    Oyama, J.2    Maeda, T.3    Koyanagi, M.4    Higuchi, Y.5    Tsuchida, K.6
  • 41
    • 84857914041 scopus 로고    scopus 로고
    • Agerelated changes in the function of autophagy in rat kidneys
    • Cui J, Bai XY, Shi S, Cui S, Hong Q, Cai G, Chen X. Agerelated changes in the function of autophagy in rat kidneys. Age (Dordr). 2012; 34:329-39. doi: 10.1007/s11357-011-9237-1
    • (2012) Age (Dordr) , vol.34 , pp. 329-339
    • Cui, J.1    Bai, X.Y.2    Shi, S.3    Cui, S.4    Hong, Q.5    Cai, G.6    Chen, X.7
  • 42
    • 84862308683 scopus 로고    scopus 로고
    • Autophagic activity in thymus and liver during aging
    • Uddin MN, Nishio N, Ito S, Suzuki H, Isobe K. Autophagic activity in thymus and liver during aging. Age (Dordr). 2012; 34:75-85. doi: 10.1007/s11357-011-9221-9
    • (2012) Age (Dordr) , vol.34 , pp. 75-85
    • Uddin, M.N.1    Nishio, N.2    Ito, S.3    Suzuki, H.4    Isobe, K.5
  • 44
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and life-span extension in C. elegans
    • Meléndez A, Tallóczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science. 2003; 301:1387-91. doi: 10.1126/science.1087782
    • (2003) Science , vol.301 , pp. 1387-1391
    • Meléndez, A.1    Tallóczy, Z.2    Seaman, M.3    Eskelinen, E.L.4    Hall, D.H.5    Levine, B.6
  • 45
    • 36849021043 scopus 로고    scopus 로고
    • Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
    • Juhász G, Erdi B, Sass M, Neufeld TP. Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes Dev. 2007; 21:3061-66. doi: 10.1101/gad.1600707
    • (2007) Genes Dev , vol.21 , pp. 3061-3066
    • Juhász, G.1    Erdi, B.2    Sass, M.3    Neufeld, T.P.4
  • 46
    • 65549139675 scopus 로고    scopus 로고
    • Regulation of the aging process by autophagy
    • Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol Med. 2009; 15:217-24. doi: 10.1016/j.molmed.2009.03.004
    • (2009) Trends Mol Med , vol.15 , pp. 217-224
    • Salminen, A.1    Kaarniranta, K.2
  • 47
    • 72649091698 scopus 로고    scopus 로고
    • Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
    • Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, Foley A, Partridge L. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab. 2010; 11:35-46. doi: 10.1016/j.cmet.2009.11.010
    • (2010) Cell Metab , vol.11 , pp. 35-46
    • Bjedov, I.1    Toivonen, J.M.2    Kerr, F.3    Slack, C.4    Jacobson, J.5    Foley, A.6    Partridge, L.7
  • 48
    • 84864008371 scopus 로고    scopus 로고
    • Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress
    • Wang M, Miller RA. Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress. Aging Cell. 2012; 11:668-74. doi: 10.1111/j.1474-9726.2012.00833.x
    • (2012) Aging Cell , vol.11 , pp. 668-674
    • Wang, M.1    Miller, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.