Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts

Molecular Cell

Volumn 64, Issue 3, 2016, Pages 593-606

  Deshpande, Rajashree A ^a   Lee, Ji Hoon ^a   Arora, Sucheta ^a   Paull, Tanya T ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CARBOXY TERMINAL BINDING PROTEIN INTERACTING PROTEIN; DNA FRAGMENT; DNA LIGASE; ENDONUCLEASE; EXONUCLEASE; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CELL CYCLE PROTEIN; DNA ADDUCT; DNA BINDING PROTEIN; MRE11A PROTEIN, HUMAN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; RAD50 PROTEIN, HUMAN; RBBP8 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DNA ADDUCT; DNA DEGRADATION; DNA STRAND; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INSECT CELL; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REGULATORY MECHANISM; ANIMAL; BACULOVIRIDAE; DNA CLEAVAGE; DNA REPAIR; ENZYME SPECIFICITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; SF9 CELL LINE; SIGNAL TRANSDUCTION; SPODOPTERA;

ANIMALS; BACULOVIRIDAE; CARRIER PROTEINS; CELL CYCLE PROTEINS; DNA ADDUCTS; DNA BREAKS, DOUBLE-STRANDED; DNA CLEAVAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; RECOMBINANT PROTEINS; SF9 CELLS; SIGNAL TRANSDUCTION; SPODOPTERA; SUBSTRATE SPECIFICITY;

EID: 84995460857     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.10.010     Document Type: Article

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