Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

Nature Communications

Volumn 7, Issue , 2016, Pages

  Felix, Jan ^a,b   Kandiah, Eaazhisai ^c   De Munck, Steven ^a,b   Bloch, Yehudi ^a,b   Van Zundert, Gydo C P ^d   Pauwels, Kris ^e   Dansercoer, Ann ^a,b   Novanska, Katka ^f   Read, Randy J ^g   Bonvin, Alexandre M J J ^d   Vergauwen, Bjorn ^a   Verstraete, Kenneth ^a,b   Gutsche, Irina ^c   Savvides, Savvas N ^b  

^a GHENT UNIVERSITY   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c CEA GRENOBLE   (France)

^d UTRECHT UNIVERSITY   (Netherlands)

^e VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^f MASARYK UNIVERSITY   (Czech Republic)

^g UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DECOY RECEPTOR GIF; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; UNCLASSIFIED DRUG; VIRAL PROTEIN; GIF PROTEIN, ORF VIRUS; MULTIPROTEIN COMPLEX; PROTEIN BINDING;

GENE EXPRESSION; IMMUNE RESPONSE; IMMUNE SYSTEM; MAMMAL; MOLECULAR ANALYSIS; PATHOGEN; PROTEIN; REACTION KINETICS; VIRUS;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION; KINETICS; NONHUMAN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; CHEMISTRY; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR MODEL; PARAPOXVIRUS; POXVIRUS INFECTION; VIROLOGY; X RAY CRYSTALLOGRAPHY;

MAMMALIA; ORF VIRUS; POXVIRIDAE;

CRYSTALLOGRAPHY, X-RAY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERLEUKIN-2; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PARAPOXVIRUS; POXVIRIDAE INFECTIONS; PROTEIN BINDING; VIRAL PROTEINS;

EID: 84994432322     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13228     Document Type: Article

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