Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity

Structure

Volumn 23, Issue 7, 2015, Pages 1199-1213

  Couñago, Rafael M ^a,c   Knapp, Karen M ^a,b   Nakatani, Yoshio ^a   Fleming, Stephen B ^a   Corbett, Michael ^a   Wise, Lyn M ^a   Mercer, Andrew A ^a   Krause, Kurt L ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b BANGOR UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHEMOKINE; CHEMOKINE BINDING PROTEIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOSAMINOGLYCAN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; PROTEIN BINDING; SOLUTION AND SOLUBILITY; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CHROMATOGRAPHY; CRYSTAL STRUCTURE; DISSOCIATION; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR WEIGHT; NONHUMAN; ORF VIRUS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; STATIC ELECTRICITY; AMINO ACID SEQUENCE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; SOLUTION AND SOLUBILITY; X RAY CRYSTALLOGRAPHY;

ORF VIRUS; POXVIRIDAE;

AMINO ACID SEQUENCE; BINDING SITES; CHEMOKINES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ORF VIRUS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; VIRAL PROTEINS;

EID: 84936847326     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2015.04.023     Document Type: Article

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