Cowpox Virus Exploits the Endoplasmic Reticulum Retention Pathway to Inhibit MHC Class I Transport to the Cell Surface

Cell Host and Microbe

Volumn 2, Issue 5, 2007, Pages 306-315

  Byun, Minji ^a   Wang, Xiaoli ^b   Pak, Melissa ^a   Hansen, Ted H ^b   Yokoyama, Wayne M ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CELLBIO; MICROBIO; MOLIMMUNO

Indexed keywords

CD11B ANTIGEN; COWPOX VIRUS 203 PROTEIN; CPXV203 PROTEIN; GLYCOPROTEIN P 15095; HERMES ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL STRAIN L 929; CELL SURFACE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; COWPOX VIRUS; DOWN REGULATION; ENDOPLASMIC RETICULUM; FIBROBLAST; GOLGI COMPLEX; HUMAN; HUMAN CELL; INHIBITION KINETICS; INTRACELLULAR TRANSPORT; LEUKEMIA CELL LINE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; ORTHOPOXVIRUS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TRANSPORT; RODENT; T LYMPHOCYTE; VERO CELL; VIRUS ISOLATION; VIRUS VIRULENCE;

ANIMALS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; COWPOX; COWPOX VIRUS; DOWN-REGULATION; ENDOPLASMIC RETICULUM; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PROTEIN TRANSPORT; VIRAL PROTEINS;

COWPOX VIRUS; ORTHOPOXVIRUS;

EID: 35848929278     PISSN: 19313128     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chom.2007.09.002     Document Type: Article

References (35)

1. Andres D.A., Dickerson I.M., and Dixon J.E. Variants of the carboxyl-terminal KDEL sequence direct intracellular retention. J. Biol. Chem. 265 (1990) 5952-5955
2. Andres D.A., Rhodes J.D., Meisel R.L., and Dixon J.E. Characterization of the carboxyl-terminal sequences responsible for protein retention in the endoplasmic reticulum. J. Biol. Chem. 266 (1991) 14277-14282
3. Barry M., Hnatiuk S., Mossman K., Lee S.F., Boshkov L., and McFadden G. The myxoma virus M-T4 gene encodes a novel RDEL-containing protein that is retained within the endoplasmic reticulum and is important for the productive infection of lymphocytes. Virology 239 (1997) 360-377
4. Boshkov L.K., Macen J.L., and McFadden G. Virus-induced loss of class I MHC antigens from the surface of cells infected with myxoma virus and malignant rabbit fibroma virus. J. Immunol. 148 (1992) 881-887
5. Breman J.G., Kalisa R., Steniowski M.V., Zanotto E., Gromyko A.I., and Arita I. Human monkeypox, 1970-79. Bull. World Health Organ. 58 (1980) 165-182
6. Campbell J.A., Trossman D.S., Yokoyama W.M., and Carayannopoulos L.N. Zoonotic orthopoxviruses encode a high-affinity antagonist of NKG2D. J. Exp. Med. 204 (2007) 1311-1317
7. Chantrey J., Meyer H., Baxby D., Begon M., Bown K.J., Hazel S.M., Jones T., Montgomery W.I., and Bennett M. Cowpox: Reservoir hosts and geographic range. Epidemiol. Infect. 122 (1999) 455-460
8. Chen N., Li G., Liszewski M.K., Atkinson J.P., Jahrling P.B., Feng Z., Schriewer J., Buck C., Wang C., Lefkowitz E.J., et al. Virulence differences between monkeypox virus isolates from West Africa and the Congo basin. Virology 340 (2005) 46-63
9. Dasgupta A., Hammarlund E., Slifka M.K., and Fruh K. Cowpox virus evades CTL recognition and inhibits the intracellular transport of MHC class I molecules. J. Immunol. 178 (2007) 1654-1661
10. Earl P.L., Moss B., Wyatt L.S., and Carroll M.W. Generation of recombinant vaccinia viruses. Current Protocols in Molecular Biology (1998), John Wiley & Sons, Hoboken, NJ 16.17.11-16.17.19
11. Fenner F., Henderson D.A., Arita I., Jezek Z., and Ladnyi I.D. Smallpox and Its Eradication (1988), World Health Organization, Geneva
12. Foster S.O., Brink E.W., Hutchins D.L., Pifer J.M., Lourie B., Moser C.R., Cummings E.C., Kuteyi O.E., Eke R.E., Titus J.B., et al. Human monkeypox. Bull. World Health Organ. 46 (1972) 569-576
13. Guerin J.L., Gelfi J., Boullier S., Delverdier M., Bellanger F.A., Bertagnoli S., Drexler I., Sutter G., and Messud-Petit F. Myxoma virus leukemia-associated protein is responsible for major histocompatibility complex class I and Fas-CD95 down-regulation and defines scrapins, a new group of surface cellular receptor abductor proteins. J. Virol. 76 (2002) 2912-2923
14. Guidotti L.G., and Chisari F.V. To kill or to cure: Options in host defense against viral infection. Curr. Opin. Immunol. 8 (1996) 478-483
15. Hnatiuk S., Barry M., Zeng W., Liu L., Lucas A., Percy D., and McFadden G. Role of the C-terminal RDEL motif of the myxoma virus M-T4 protein in terms of apoptosis regulation and viral pathogenesis. Virology 263 (1999) 290-306
16. Jezek Z., Szczeniowski M., Paluku K.M., and Mutombo M. Human monkeypox: Clinical features of 282 patients. J. Infect. Dis. 156 (1987) 293-298
17. Ladnyj I.D., Ziegler P., and Kima E. A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo. Bull. World Health Organ. 46 (1972) 593-597
18. Lewis-Jones S. Zoonotic poxvirus infections in humans. Curr. Opin. Infect. Dis. 17 (2004) 81-89
19. Likos A.M., Sammons S.A., Olson V.A., Frace A.M., Li Y., Olsen-Rasmussen M., Davidson W., Galloway R., Khristova M.L., Reynolds M.G., et al. A tale of two clades: Monkeypox viruses. J. Gen. Virol. 86 (2005) 2661-2672
20. Liu X., Kremer M., and Broyles S.S. A natural vaccinia virus promoter with exceptional capacity to direct protein synthesis. J. Virol. Methods 122 (2004) 141-145
21. Lybarger L., Wang X., Harris M.R., Virgin IV H.W., and Hansen T.H. Virus subversion of the MHC class I peptide-loading complex. Immunity 18 (2003) 121-130
22. Martinez M.J., Bray M.P., and Huggins J.W. A mouse model of aerosol-transmitted orthopoxviral disease: Morphology of experimental aerosol-transmitted orthopoxviral disease in a cowpox virus-BALB/c mouse system. Arch. Pathol. Lab. Med. 124 (2000) 362-377
23. Meyer H., Neubauer H., and Pfeffer M. Amplification of 'variola virus-specific' sequences in German cowpox virus isolates. J. Vet. Med. B Infect. Dis. Vet. Public Health 49 (2002) 17-19
24. Pamer E., and Cresswell P. Mechanisms of MHC class I-restricted antigen processing. Annu. Rev. Immunol. 16 (1998) 323-358
25. Pelham H.R. The dynamic organisation of the secretory pathway. Cell Struct. Funct. 21 (1996) 413-419
26. Reed K.D., Melski J.W., Graham M.B., Regnery R.L., Sotir M.J., Wegner M.V., Kazmierczak J.J., Stratman E.J., Li Y., Fairley J.A., et al. The detection of monkeypox in humans in the Western Hemisphere. N. Engl. J. Med. 350 (2004) 342-350
27. Sasada T., Ghendler Y., Neveu J.M., Lane W.S., and Reinherz E.L. A naturally processed mitochondrial self-peptide in complex with thymic MHC molecules functions as a selecting ligand for a viral-specific T cell receptor. J. Exp. Med. 194 (2001) 883-892
28. Sbrana E., Xiao S.Y., Newman P.C., and Tesh R.B. Comparative pathology of North American and central African strains of monkeypox virus in a ground squirrel model of the disease. Am. J. Trop. Med. Hyg. 76 (2007) 155-164
29. Seet B.T., Johnston J.B., Brunetti C.R., Barrett J.W., Everett H., Cameron C., Sypula J., Nazarian S.H., Lucas A., and McFadden G. Poxviruses and immune evasion. Annu. Rev. Immunol. 21 (2003) 377-423
30. Shchelkunov S., Totmenin A., and Kolosova I. Species-specific differences in organization of orthopoxvirus kelch-like proteins. Virus Genes 24 (2002) 157-162
31. Smith G.L., and McFadden G. Smallpox: Anything to declare?. Nat. Rev. Immunol. 2 (2002) 521-527
32. Tortorella D., Gewurz B.E., Furman M.H., Schust D.J., and Ploegh H.L. Viral subversion of the immune system. Annu. Rev. Immunol. 18 (2000) 861-926
33. Townsend A., Ohlen C., Bastin J., Ljunggren H.G., Foster L., and Karre K. Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 340 (1989) 443-448
34. Vennema H., Heijnen L., Rottier P.J., Horzinek M.C., and Spaan W.J. A novel glycoprotein of feline infectious peritonitis coronavirus contains a KDEL-like endoplasmic reticulum retention signal. J. Virol. 66 (1992) 4951-4956
35. Zuniga M.C., Wang H., Barry M., and McFadden G. Endosomal/lysosomal retention and degradation of major histocompatibility complex class I molecules is induced by myxoma virus. Virology 261 (1999) 180-192