Artemisinin biosynthesis in Artemisia annua and metabolic engineering: questions, challenges, and perspectives

Phytochemistry Reviews

Volumn 15, Issue 6, 2016, Pages 1093-1114

  Xie, De Yu ^a   Ma, Dong Ming ^a   Judd, Rika ^a   Jones, Ashley Loray ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Artemisia annua; Artemisinin; Genetics; Malaria; Metabolic profiling; Sesquiterpenoid; Terpenoid

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; ALCOHOL DEHYDROGENASE; ALDEHYDE; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; ARTEMISININ; CYTOCHROME P450; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANTIMALARIAL ACTIVITY; ARTEMISIA ANNUA; BIOSYNTHESIS; CHEMICAL BOND; CYCLIZATION; DEHYDROGENATION; DOUBLE BOND REDUCTION; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; GENE ISOLATION; GENETIC ANALYSIS; GENETIC BREEDING; GENETIC PROCEDURES; GERMPLASM; ISOTOPE LABELING; MALARIA; MALARIA CONTROL; METABOLIC ENGINEERING; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGENATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SYNTHETIC BIOLOGY;

EID: 84994291465     PISSN: 15687767     EISSN: 1572980X     Source Type: Journal    
DOI: 10.1007/s11101-016-9480-2     Document Type: Review

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