Clostridium difficile toxins TcdA and TcdB cause colonic tissue damage by distinct mechanisms

Infection and Immunity

Volumn 84, Issue 10, 2016, Pages 2871-2877

  Chumbler, Nicole M ^a   Farrow, Melissa A ^a   Lapierre, Lynne A ^a,b,c   Franklin, Jeffrey L ^a,b,c   Lacy, D Borden ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 7; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; GLUCOSYLTRANSFERASE; BACTERIAL TOXIN; ENTEROTOXIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL IMMORTALIZATION; CELL MEMBRANE; CELL VIABILITY; COLON INJURY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; EXPLANT; INTESTINE EPITHELIUM CELL; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; YOUNG ADULT; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; COLON; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; METABOLISM; PATHOGENICITY; PEPTOCLOSTRIDIUM DIFFICILE;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BACTERIAL TOXINS; CELL DEATH; CELLS, CULTURED; CLOSTRIDIUM DIFFICILE; COLON; ENTEROTOXINS; EPITHELIAL CELLS; GLUCOSYLTRANSFERASES; MICE;

EID: 84994238832     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00583-16     Document Type: Article

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