Pyknotic cell death induced by Clostridium difficile TcdB: Chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity

Cellular Microbiology

Volumn 16, Issue 11, 2014, Pages 1678-1692

  Wohlan, Katharina ^a   Goy, Sebastian ^a   Olling, Alexandra ^a   Srivaratharajan, Sangar ^a   Tatge, Helma ^a   Genth, Harald ^a   Gerhard, Ralf ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BAFILOMYCIN A1; CLOSTRIDIUM TOXIN; CLOSTRIDIUM TOXIN TCDB; GLUCOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL TOXIN; CHROMATIN; HISTONE; MUTANT PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

APOPTOSIS; ARTICLE; BLISTER; CELL NUCLEUS MEMBRANE; CELL VIABILITY; CHROMATIN CONDENSATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME GLYCOSYLATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MELANOMA CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PEPTOCLOSTRIDIUM DIFFICILE; PHENOTYPE; PRIORITY JOURNAL; CELL DEATH; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; CHROMATIN; DRUG EFFECTS; GENETICS; GLYCOSYLATION; LIVER CELL; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN PROCESSING;

CLOSTRIDIUM DIFFICILE;

BACTERIAL PROTEINS; BACTERIAL TOXINS; CELL DEATH; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; CHROMATIN; GLUCOSYLTRANSFERASES; GLYCOSYLATION; HEPATOCYTES; HISTONES; HUMANS; MUTANT PROTEINS; NUCLEAR ENVELOPE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE OXYGEN SPECIES; RHO GTP-BINDING PROTEINS;

EID: 84916633158     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/cmi.12317     Document Type: Article

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