Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

Neurochemistry International

Volumn 111, Issue , 2017, Pages 69-81

  Zhang, Yanlu ^a   Chopp, Michael ^a,b   Zhang, Zheng Gang ^a   Katakowski, Mark ^a   Xin, Hongqi ^a   Qu, Changsheng ^a   Ali, Meser ^a   Mahmood, Asim ^a   Xiong, Ye ^a  

^a HENRY FORD HOSPITAL   (United States)

^b OAKLAND UNIVERSITY   (United States)

Author keywords

Exosomes; Function recovery; Human mesenchymal stem cell (hMSC); Neuroinflammation; Scaffolds; Traumatic brain injury

Indexed keywords

COLLAGEN TYPE 1; GLIAL FIBRILLARY ACIDIC PROTEIN; LIPOSOME;

ADULT; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL COUNTING; CELL FREE SYSTEM; CELL PROLIFERATION; COGNITION; COMPARATIVE STUDY; CONTROLLED STUDY; CONVALESCENCE; DENTATE GYRUS; DISEASE SEVERITY; ENDOTHELIUM CELL; EXOSOME; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIMIT OF QUANTITATION; MALE; MORRIS WATER MAZE TEST; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; SPATIAL LEARNING; SPATIAL MEMORY; SYSTEMIC THERAPY; TRAUMATIC BRAIN INJURY; VASCULAR REMODELING; ANIMAL; CELL CULTURE TECHNIQUE; DISEASE MODEL; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; PROCEDURES; WISTAR RAT;

ANIMALS; BRAIN INJURIES, TRAUMATIC; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; EXOSOMES; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; NEUROGENESIS; RATS, WISTAR; RECOVERY OF FUNCTION;

EID: 84994130140     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2016.08.003     Document Type: Article

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