-
1
-
-
38949210805
-
Podocytes use FcRn to clear IgG from the glomerular basement membrane
-
Akilesh S, Huber TB, Wu H, Wang G, Hartleben B, Kopp JB, Miner JH, Roopenian DC, Unanue ER, Shaw AS. Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc Natl Acad Sci USA 105: 967–972, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 967-972
-
-
Akilesh, S.1
Huber, T.B.2
Wu, H.3
Wang, G.4
Hartleben, B.5
Kopp, J.B.6
Miner, J.H.7
Roopenian, D.C.8
Unanue, E.R.9
Shaw, A.S.10
-
2
-
-
84928614493
-
Insulin-like growth factors and kidney disease
-
Epub before print
-
Bach LA, Hale LJ. Insulin-like growth factors and kidney disease. Am J Kidney Dis [Epub before print].
-
Am J Kidney Dis
-
-
Bach, L.A.1
Hale, L.J.2
-
3
-
-
81155123707
-
Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes
-
Bertuccio C, Veron D, Aggarwal PK, Holzman L, Tufro A. Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. J Biol Chem 286: 39933– 39944, 2011.
-
(2011)
J Biol Chem
, vol.286
-
-
Bertuccio, C.1
Veron, D.2
Aggarwal, P.K.3
Holzman, L.4
Tufro, A.5
-
4
-
-
2342431290
-
Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities
-
Bjarnegard M, Enge M, Norlin J, Gustafsdottir S, Fredriksson S, Abramsson A, Takemoto M, Gustafsson E, Fassler R, Betsholtz C. Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities. Development 131: 1847–1857, 2004.
-
(2004)
Development
, vol.131
, pp. 1847-1857
-
-
Bjarnegard, M.1
Enge, M.2
Norlin, J.3
Gustafsdottir, S.4
Fredriksson, S.5
Abramsson, A.6
Takemoto, M.7
Gustafsson, E.8
Fassler, R.9
Betsholtz, C.10
-
5
-
-
0035132560
-
Familial nephropathy differing from minimal change nephropathy and focal glomerulosclerosis
-
Branten AJ, van den Born J, Jansen JL, Assmann KJ, Wetzels JF. Familial nephropathy differing from minimal change nephropathy and focal glomerulosclerosis. Kidney Int 59: 693–701, 2001.
-
(2001)
Kidney Int
, vol.59
, pp. 693-701
-
-
Branten, A.J.1
Van Den Born, J.2
Jansen, J.L.3
Assmann, K.J.4
Wetzels, J.F.5
-
6
-
-
78649318718
-
Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus
-
Broekhuizen LN, Lemkes BA, Mooij HL, Meuwese MC, Verberne H, Holleman F, Schlingemann RO, Nieuwdorp M, Stroes ES, Vink H. Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus. Diabetologia 53: 2646–2655, 2010.
-
(2010)
Diabetologia
, vol.53
, pp. 2646-2655
-
-
Broekhuizen, L.N.1
Lemkes, B.A.2
Mooij, H.L.3
Meuwese, M.C.4
Verberne, H.5
Holleman, F.6
Schlingemann, R.O.7
Nieuwdorp, M.8
Stroes, E.S.9
Vink, H.10
-
7
-
-
80053377598
-
Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glo-merular podocytes
-
Bu X, Zhou Y, Zhang H, Qiu W, Chen L, Cao H, Fang L, Wen P, Tan R, Yang J. Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glo-merular podocytes. Am J Physiol Renal Physiol 301: F784–F792, 2011.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. F784-F792
-
-
Bu, X.1
Zhou, Y.2
Zhang, H.3
Qiu, W.4
Chen, L.5
Cao, H.6
Fang, L.7
Wen, P.8
Tan, R.9
Yang, J.10
-
8
-
-
84903562397
-
Glomerular cell cross-talk influences composition and assembly of extracellular matrix
-
Byron A, Randles MJ, Humphries JD, Mironov A, Hamidi H, Harris S, Mathieson PW, Saleem MA, Satchell SC, Zent R, Humphries MJ, Lennon R. Glomerular cell cross-talk influences composition and assembly of extracellular matrix. J Am Soc Nephrol 25: 953–966, 2014.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 953-966
-
-
Byron, A.1
Randles, M.J.2
Humphries, J.D.3
Mironov, A.4
Hamidi, H.5
Harris, S.6
Mathieson, P.W.7
Saleem, M.A.8
Satchell, S.C.9
Zent, R.10
Humphries, M.J.11
Lennon, R.12
-
9
-
-
33751341522
-
Extracellular matrix-bound angiopoietin-like 4 inhibits endothelial cell adhesion, migration, and sprouting and alters actin cytoskeleton
-
Cazes A, Galaup A, Chomel C, Bignon M, Brechot N, Le Jan S, Weber H, Corvol P, Muller L, Germain S, Monnot C. Extracellular matrix-bound angiopoietin-like 4 inhibits endothelial cell adhesion, migration, and sprouting and alters actin cytoskeleton. Circ Res 99: 1207– 1215, 2006.
-
(2006)
Circ Res
, vol.99
-
-
Cazes, A.1
Galaup, A.2
Chomel, C.3
Bignon, M.4
Brechot, N.5
Le Jan, S.6
Weber, H.7
Corvol, P.8
Muller, L.9
Germain, S.10
Monnot, C.11
-
10
-
-
12344324985
-
Vascular endothelial growth factor is increased during early stage of diabetic nephropathy in type II diabetic rats
-
Cha DR, Kang YS, Han SY, Jee YH, Han KH, Han JY, Kim YS, Kim NH. Vascular endothelial growth factor is increased during early stage of diabetic nephropathy in type II diabetic rats. J Endocrinol 183: 183–194, 2004.
-
(2004)
J Endocrinol
, vol.183
, pp. 183-194
-
-
Cha, D.R.1
Kang, Y.S.2
Han, S.Y.3
Jee, Y.4
Han, Y.H.5
Han, J.Y.6
Kim, Y.S.7
Kim, N.H.8
-
11
-
-
84858328459
-
Role of microRNAs in kidney homeostasis and disease
-
Chandrasekaran K, Karolina DS, Sepramaniam S, Armugam A, Wintour EM, Bertram JF, Jeyaseelan K. Role of microRNAs in kidney homeostasis and disease. Kidney Int 81: 617–627, 2012.
-
(2012)
Kidney Int
, vol.81
, pp. 617-627
-
-
Chandrasekaran, K.1
Karolina, D.S.2
Sepramaniam, S.3
Armugam, A.4
Wintour, E.M.5
Bertram, J.F.6
Jeyaseelan, K.7
-
12
-
-
7044260750
-
Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes
-
Chen S, Kasama Y, Lee JS, Jim B, Marin M, Ziyadeh FN. Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes. Diabetes 53: 2939–2949, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 2939-2949
-
-
Chen, S.1
Kasama, Y.2
Lee, J.S.3
Jim, B.4
Marin, M.5
Ziyadeh, F.N.6
-
13
-
-
33846683628
-
Overexpression of cyclooxy-genase-2 predisposes to podocyte injury
-
Cheng H, Wang S, Jo YI, Hao CM, Zhang M, Fan X, Kennedy C, Breyer MD, Moeckel GW, Harris RC. Overexpression of cyclooxy-genase-2 predisposes to podocyte injury. J Am Soc Nephrol 18: 551–559, 2007.
-
(2007)
Jam Soc Nephrol
, vol.18
, pp. 551-559
-
-
Cheng, H.1
Wang, S.2
Jo, Y.I.3
Hao, C.M.4
Zhang, M.5
Fan, X.6
Kennedy, C.7
Breyer, M.D.8
Moeckel, G.W.9
Harris, R.C.10
-
14
-
-
0036423877
-
Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension
-
Cheng HF, Wang CJ, Moeckel GW, Zhang MZ, McKanna JA, Harris RC. Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension. Kidney Int 62: 929–939, 2002.
-
(2002)
Kidney Int
, vol.62
, pp. 929-939
-
-
Cheng, H.F.1
Wang, C.J.2
Moeckel, G.W.3
Zhang, M.Z.4
McKanna, J.A.5
Harris, R.C.6
-
15
-
-
84995821720
-
Partition of insulin-like growth factor (IGF)-binding sites between the IGF-I and IGF-II receptors and IGF-binding proteins in the human kidney
-
Chin E, Michels K, Bondy CA. Partition of insulin-like growth factor (IGF)-binding sites between the IGF-I and IGF-II receptors and IGF-binding proteins in the human kidney. J Clin Endocrinol Metab 78: 156–164, 1994.
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 156-164
-
-
Chin, E.1
MicHels, K.2
Bondy, C.A.3
-
16
-
-
84895549251
-
Angiopoietin-like 4 based therapeutics for proteinuria and kidney disease
-
Chugh SS, Mace C, Clement LC, Del Nogal Avila M, Marshall CB. Angiopoietin-like 4 based therapeutics for proteinuria and kidney disease. Front Pharmacol 5: 23, 2014.
-
(2014)
Front Pharmacol
, vol.5
, pp. 23
-
-
Chugh, S.S.1
MaCe, C.2
Clement, L.C.3
Del Nogal Avila, M.4
Marshall, C.B.5
-
17
-
-
78651252297
-
Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome
-
Clement LC, Avila-Casado C, Mace C, Soria E, Bakker WW, Kersten S, Chugh SS. Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med 17: 117–122, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 117-122
-
-
Clement, L.C.1
Avila-Casado, C.2
MaCe, C.3
Soria, E.4
Bakker, W.W.5
Kersten, S.6
Chugh, S.S.7
-
18
-
-
0032712434
-
Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes
-
Cooper ME, Vranes D, Youssef S, Stacker SA, Cox AJ, Rizkalla B, Casley DJ, Bach LA, Kelly DJ, Gilbert RE. Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes. Diabetes 48: 2229–2239, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 2229-2239
-
-
Cooper, M.E.1
Vranes, D.2
Youssef, S.3
Stacker, S.A.4
Cox, A.J.5
Rizkalla, B.6
Casley, D.J.7
Bach, L.A.8
Kelly, D.J.9
Gilbert, R.E.10
-
19
-
-
12144287926
-
Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy in rats
-
Cruzado JM, Lloberas N, Torras J, Riera M, Fillat C, Herrero-Fresneda I, Aran JM, Alperovich G, Vidal A, Grinyo JM. Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy in rats. Diabetes 53: 1119–1127, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 1119-1127
-
-
Cruzado, J.M.1
Lloberas, N.2
Torras, J.3
Riera, M.4
Fillat, C.5
Herrero-Fresneda, I.6
Aran, J.M.7
Alperovich, G.8
Vidal, A.9
Grinyo, J.M.10
-
20
-
-
84897492148
-
Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis
-
Daehn I, Casalena G, Zhang T, Shi S, Fenninger F, Barasch N, Yu L, D’Agati V, Schlondorff D, Kriz W, Haraldsson B, Bottinger EP. Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis. J Clin Invest 124: 1608–1621, 2014.
-
(2014)
J Clin Invest
, vol.124
, pp. 1608-1621
-
-
Daehn, I.1
Casalena, G.2
Zhang, T.3
Shi, S.4
Fenninger, F.5
Barasch, N.6
Yu, L.7
D’Agati, V.8
Schlondorff, D.9
Kriz, W.10
Haraldsson, B.11
Bottinger, E.P.12
-
21
-
-
77955877135
-
Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria
-
Dai C, Saleem MA, Holzman LB, Mathieson P, Liu Y. Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int 77: 962–973, 2010.
-
(2010)
Kidney Int
, vol.77
, pp. 962-973
-
-
Dai, C.1
Saleem, M.A.2
Holzman, L.B.3
Mathieson, P.4
Liu, Y.5
-
22
-
-
15844397902
-
Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropa-thy in mice
-
Dai C, Yang J, Bastacky S, Xia J, Li Y, Liu Y. Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropa-thy in mice. J Am Soc Nephrol 15: 2637–2647, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2637-2647
-
-
Dai, C.1
Yang, J.2
Bastacky, S.3
Xia, J.4
Li, Y.5
Liu, Y.6
-
23
-
-
84876522948
-
Glomerular endothelial surface layer acts as a barrier against albumin filtration
-
Dane MJ, van den Berg BM, Avramut MC, Faas FG, van der Vlag J, Rops AL, Ravelli RB, Koster BJ, van Zonneveld AJ, Vink H, Rabelink TJ. Glomerular endothelial surface layer acts as a barrier against albumin filtration. Am J Pathol 182: 1532–1540, 2013.
-
(2013)
Am J Pathol
, vol.182
, pp. 1532-1540
-
-
Dane, M.J.1
Van Den Berg, B.M.2
Avramut, M.C.3
Faas, F.G.4
Van Der Vlag, J.5
Rops, A.L.6
Ravelli, R.B.7
Koster, B.J.8
Zonneveld, A.J.9
Vink, H.10
Rabelink, T.J.11
-
24
-
-
77957147501
-
TGFbeta enforces activation of eukaryotic elongation factor-2 (EEF2) via inacti-vation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy
-
Das F, Ghosh-Choudhury N, Kasinath BS, Choudhury GG. TGFbeta enforces activation of eukaryotic elongation factor-2 (eEF2) via inacti-vation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy. FEBS Lett 584: 4268–4272, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 4268-4272
-
-
Das, F.1
Ghosh-Choudhury, N.2
Kasinath, B.S.3
Choudhury, G.G.4
-
25
-
-
34547628176
-
Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia
-
Davis B, Dei Cas A, Long DA, White KE, Hayward A, Ku CH, Woolf AS, Bilous R, Viberti G, Gnudi L. Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia. J Am Soc Nephrol 18: 2320–2329, 2007.
-
(2007)
Jam Soc Nephrol
, vol.18
, pp. 2320-2329
-
-
Davis, B.1
Dei Cas, A.2
Long, D.A.3
White, K.E.4
Hayward, A.5
Ku, C.H.6
Woolf, A.S.7
Bilous, R.8
Viberti, G.9
Gnudi, L.10
-
26
-
-
0027461162
-
Size- and charge selectivity of glomerular filtration in Type 1 (Insulin-dependent) diabetic patients with and without albuminuria
-
Deckert T, Kofoed-Enevoldsen A, Vidal P, Norgaard K, Andreasen HB, and Feldt-Rasmussen B. Size- and charge selectivity of glomerular filtration in Type 1 (insulin-dependent) diabetic patients with and without albuminuria. Diabetologia 36: 244–251, 1993.
-
(1993)
Diabetologia
, vol.36
, pp. 244-251
-
-
Deckert, T.1
Kofoed-Enevoldsen, A.2
Vidal, P.3
Norgaard, K.4
Andreasen, H.B.5
Feldt-Rasmussen, B.6
-
27
-
-
84907520196
-
Signaling pathway cooperation in TGF-beta-induced epithelial-mesenchymal transition
-
Derynck R, Muthusamy BP, Saeteurn KY. Signaling pathway cooperation in TGF-beta-induced epithelial-mesenchymal transition. Curr Opin Cell Biol 31: 56–66, 2014.
-
(2014)
Curr Opin Cell Biol
, vol.31
, pp. 56-66
-
-
Derynck, R.1
Muthusamy, B.P.2
Saeteurn, K.Y.3
-
28
-
-
84891784154
-
Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease
-
Dessapt-Baradez C, Woolf AS, White KE, Pan J, Huang JL, Hay-ward AA, Price KL, Kolatsi-Joannou M, Locatelli M, Diennet M, Webster Z, Smillie SJ, Nair V, Kretzler M, Cohen CD, Long DA, Gnudi L. Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease. J Am Soc Nephrol 25: 33–42, 2014.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 33-42
-
-
Dessapt-Baradez, C.1
Woolf, A.S.2
White, K.E.3
Pan, J.4
Huang, J.L.5
Hay-Ward, A.A.6
Price, K.L.7
Kolatsi-Joannou, M.8
Locatelli, M.9
Diennet, M.10
Webster, Z.11
Smillie, S.J.12
Nair, V.13
Kretzler, M.14
Cohen, C.D.15
Long, D.A.16
Gnudi, L.17
-
29
-
-
0035034655
-
Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes
-
de Vriese AS, Tilton RG, Elger M, Stephan CC, Kriz W, Lameire NH. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol 12: 993–1000, 2001.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 993-1000
-
-
De Vriese, A.S.1
Tilton, R.G.2
Elger, M.3
Stephan, C.C.4
Kriz, W.5
Lameire, N.H.6
-
30
-
-
6344282521
-
Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria
-
Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obes Res 12: 1278– 1289, 2004.
-
(2004)
Obes Res
, vol.12
-
-
Dey, A.1
Williams, R.S.2
Pollock, D.M.3
Stepp, D.W.4
Newman, J.W.5
Hammock, B.D.6
Imig, J.D.7
-
31
-
-
84906540059
-
The endothelin antagonist atrasentan lowers residual albu-minuria in patients with type 2 diabetic nephropathy
-
de Zeeuw D, Coll B, Andress D, Brennan JJ, Tang H, Houser M, Correa-Rotter R, Kohan D, Lambers Heerspink HJ, Makino H, Perkovic V, Pritchett Y, Remuzzi G, Tobe SW, Toto R, Viberti G, Parving HH. The endothelin antagonist atrasentan lowers residual albu-minuria in patients with type 2 diabetic nephropathy. J Am Soc Nephrol 25: 1083–1093, 2014.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 1083-1093
-
-
De Zeeuw, D.1
Coll, B.2
Andress, D.3
Brennan, J.J.4
Tang, H.5
Houser, M.6
Correa-Rotter, R.7
Kohan, D.8
Lambers Heerspink, H.J.9
Makino, H.10
Perkovic, V.11
Pritchett, Y.12
Remuzzi, G.13
Tobe, S.W.14
Toto, R.15
Viberti, G.16
Parving, H.H.17
-
32
-
-
0344389419
-
Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury
-
Dworkin LD, Gong R, Tolbert E, Centracchio J, Yano N, Zanabli AR, Esparza A, Rifai A. Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury. Kidney Int 65: 409–419, 2004.
-
(2004)
Kidney Int
, vol.65
, pp. 409-419
-
-
Dworkin, L.D.1
Gong, R.2
Tolbert, E.3
Centracchio, J.4
Yano, N.5
Zanabli, A.R.6
Esparza, A.7
Rifai, A.8
-
33
-
-
40849130173
-
VEGF inhibition and renal thrombotic microangiopathy
-
Eremina V, Jefferson JA, Kowalewska J, Hochster H, Haas M, Weisstuch J, Richardson C, Kopp JB, Kabir MG, Backx PH, Gerber HP, Ferrara N, Barisoni L, Alpers CE, Quaggin SE. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 358: 1129–1136, 2008.
-
(2008)
N Engl J Med
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
Hochster, H.4
Haas, M.5
Weisstuch, J.6
Richardson, C.7
Kopp, J.B.8
Kabir, M.G.9
Backx, P.H.10
Gerber, H.P.11
Ferrara, N.12
Barisoni, L.13
Alpers, C.E.14
Quaggin, S.E.15
-
34
-
-
0037370325
-
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
-
Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, Ferrara N, Gerber HP, Kikkawa Y, Miner JH, Quaggin SE. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 111: 707–716, 2003.
-
(2003)
Jclininvest
, vol.111
, pp. 707-716
-
-
Eremina, V.1
Sood, M.2
Haigh, J.3
Nagy, A.4
Lajoie, G.5
Ferrara, N.6
Gerber, H.P.7
Kikkawa, Y.8
Miner, J.H.9
Quaggin, S.E.10
-
35
-
-
38149107161
-
A new look at platelet-derived growth factor in renal disease
-
Floege J, Eitner F, Alpers CE. A new look at platelet-derived growth factor in renal disease. J Am Soc Nephrol 19: 12–23, 2008.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 12-23
-
-
Floege, J.1
Eitner, F.2
Alpers, C.E.3
-
36
-
-
0036789207
-
Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody
-
Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R. Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody. Diabetes 51: 3090–3094, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 3090-3094
-
-
Flyvbjerg, A.1
Dagnaes-Hansen, F.2
De Vriese, A.S.3
Schrijvers, B.F.4
Tilton, R.G.5
Rasch, R.6
-
37
-
-
77955097036
-
The glomerulus–a view from the inside–the endothe-lial cell
-
Fogo AB, Kon V. The glomerulus–a view from the inside–the endothe-lial cell. Int J Biochem Cell Biol 42: 1388–1397, 2010.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1388-1397
-
-
Fogo, A.B.1
Kon, V.2
-
38
-
-
0035142883
-
Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis
-
Fornoni A, Li H, Foschi A, Striker GE, Striker LJ. Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis. Am J Pathol 158: 275–280, 2001.
-
(2001)
Am J Pathol
, vol.158
, pp. 275-280
-
-
Fornoni, A.1
Li, H.2
Foschi, A.3
Striker, G.E.4
Striker, L.J.5
-
39
-
-
79957801362
-
The glomerular endothelial cell coat is essential for glomerular filtration
-
Friden V, Oveland E, Tenstad O, Ebefors K, Nystrom J, Nilsson UA, Haraldsson B. The glomerular endothelial cell coat is essential for glomerular filtration. Kidney Int 79: 1322–1330, 2011.
-
(2011)
Kidney Int
, vol.79
, pp. 1322-1330
-
-
Friden, V.1
Oveland, E.2
Tenstad, O.3
Ebefors, K.4
Nystrom, J.5
Nilsson, U.A.6
Haraldsson, B.7
-
40
-
-
18644382318
-
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1
-
Gale NW, Thurston G, Hackett SF, Renard R, Wang Q, McClain J, Martin C, Witte C, Witte MH, Jackson D, Suri C, Campochiaro PA, Wiegand SJ, Yancopoulos GD. Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1. Dev Cell 3: 411–423, 2002.
-
(2002)
Dev Cell
, vol.3
, pp. 411-423
-
-
Gale, N.W.1
Thurston, G.2
Hackett, S.F.3
Renard, R.4
Wang, Q.5
McClain, J.6
Martin, C.7
Witte, C.8
Witte, M.H.9
Jackson, D.10
Suri, C.11
Campochiaro, P.A.12
Wiegand, S.J.13
Yancopoulos, G.D.14
-
41
-
-
0033135876
-
Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and eph-rins in vascular development
-
Gale NW, Yancopoulos GD. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and eph-rins in vascular development. Genes Dev 13: 1055–1066, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 1055-1066
-
-
Gale, N.W.1
Yancopoulos, G.D.2
-
42
-
-
84555188487
-
Heparanase is essential for the development of diabetic nephropathy in mice
-
Gil N, Goldberg R, Neuman T, Garsen M, Zcharia E, Rubinstein AM, van Kuppevelt T, Meirovitz A, Pisano C, Li JP, van der Vlag J, Vlodavsky I, Elkin M. Heparanase is essential for the development of diabetic nephropathy in mice. Diabetes 61: 208–216, 2012.
-
(2012)
Diabetes
, vol.61
, pp. 208-216
-
-
Gil, N.1
Goldberg, R.2
Neuman, T.3
Garsen, M.4
Zcharia, E.5
Rubinstein, A.M.6
Van Kuppevelt, T.7
Meirovitz, A.8
Pisano, C.9
Li, J.P.10
Van Der Vlag, J.11
Vlodavsky, I.12
Elkin, M.13
-
43
-
-
84864397281
-
Cellular and molecular mechanisms of diabetic glomerulopa-thy
-
Gnudi L. Cellular and molecular mechanisms of diabetic glomerulopa-thy. Nephrol Dial Transplant 27: 2642–2649, 2012.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 2642-2649
-
-
Gnudi, L.1
-
44
-
-
33746610964
-
Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP
-
Guan F, Villegas G, Teichman J, Mundel P, Tufro A. Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP. Am J Physiol Renal Physiol 291: F422–F428, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
, pp. F422-F428
-
-
Guan, F.1
Villegas, G.2
Teichman, J.3
Mundel, P.4
Tufro, A.5
-
45
-
-
84876138192
-
Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse
-
Hale LJ, Welsh GI, Perks CM, Hurcombe JA, Moore S, Hers I, Saleem MA, Mathieson PW, Murphy AJ, Jeansson M, Holly JM, Hardouin SN, Coward RJ. Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse. J Pathol 230: 95–106, 2013.
-
(2013)
J Pathol
, vol.230
, pp. 95-106
-
-
Hale, L.J.1
Welsh, G.I.2
Perks, C.M.3
Hurcombe, J.A.4
Moore, S.5
Hers, I.6
Saleem, M.A.7
Mathieson, P.W.8
Murphy, A.J.9
Jeansson, M.10
Holly, J.M.11
Hardouin, S.N.12
Coward, R.J.13
-
46
-
-
42149122041
-
Properties of the glomerular barrier and mechanisms of proteinuria
-
Haraldsson B, Nystrom J, Deen WM. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88: 451–487, 2008.
-
(2008)
Physiol Rev
, vol.88
, pp. 451-487
-
-
Haraldsson, B.1
Nystrom, J.2
Deen, W.M.3
-
47
-
-
84891499916
-
The endothelium as part of the integrative glomerular barrier complex
-
Haraldsson BS. The endothelium as part of the integrative glomerular barrier complex. Kidney Int 85: 8–11, 2014.
-
(2014)
Kidney Int
, vol.85
, pp. 8-11
-
-
Haraldsson, B.S.1
-
48
-
-
84857708170
-
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
-
Hergenreider E, Heydt S, Treguer K, Boettger T, Horrevoets AJ, Zeiher AM, Scheffer MP, Frangakis AS, Yin X, Mayr M, Braun T, Urbich C, Boon RA, Dimmeler S. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol 14: 249–256, 2012.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 249-256
-
-
Hergenreider, E.1
Heydt, S.2
Treguer, K.3
Boettger, T.4
Horrevoets, A.J.5
Zeiher, A.M.6
Scheffer, M.P.7
Frangakis, A.S.8
Yin, X.9
Mayr, M.10
Braun, T.11
Urbich, C.12
Boon, R.A.13
Dimmeler, S.14
-
49
-
-
0346728703
-
Electron microscopic evaluation of the endothelial surface layer of glomerular capillaries
-
Hjalmarsson C, Johansson BR, Haraldsson B. Electron microscopic evaluation of the endothelial surface layer of glomerular capillaries. Microvasc Res 67: 9–17, 2004.
-
(2004)
Microvasc Res
, vol.67
, pp. 9-17
-
-
Hjalmarsson, C.1
Johansson, B.R.2
Haraldsson, B.3
-
50
-
-
84872047522
-
Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli
-
Hodgin JB, Nair V, Zhang H, Randolph A, Harris RC, Nelson RG, Weil EJ, Cavalcoli JD, Patel JM, Brosius FC, 3rd, Kretzler M.Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli. Diabetes 62: 299–308, 2013.
-
(2013)
Diabetes
, vol.62
, pp. 299-308
-
-
Hodgin, J.B.1
Nair, V.2
Zhang, H.3
Randolph, A.4
Harris, R.C.5
Nelson, R.G.6
Weil, E.J.7
Cavalcoli, J.D.8
Patel, J.M.9
Brosius, F.C.10
Kretzler, M.11
-
51
-
-
79957880117
-
Angiopoietin-1 is essential in mouse vasculature during development and in response to injury
-
Jeansson M, Gawlik A, Anderson G, Li C, Kerjaschki D, Henkelman M, Quaggin SE. Angiopoietin-1 is essential in mouse vasculature during development and in response to injury. J Clin Invest 121: 2278–2289, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 2278-2289
-
-
Jeansson, M.1
Gawlik, A.2
Erson, G.3
Li, C.4
Kerjaschki, D.5
Henkelman, M.6
Quaggin, S.E.7
-
52
-
-
33644806727
-
Morphological and functional evidence for an important role of the endothelial cell glycocalyx in the glomerular barrier
-
Jeansson M, Haraldsson B. Morphological and functional evidence for an important role of the endothelial cell glycocalyx in the glomerular barrier. Am J Physiol Renal Physiol 290: F111–F116, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.290
, pp. F111-F116
-
-
Jeansson, M.1
Haraldsson, B.2
-
53
-
-
84867519785
-
Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function
-
Jin J, Sison K, Li C, Tian R, Wnuk M, Sung HK, Jeansson M, Zhang C, Tucholska M, Jones N, Kerjaschki D, Shibuya M, Fantus IG, Nagy A, Gerber HP, Ferrara N, Pawson T, Quaggin SE. Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell 151: 384–399, 2012.
-
(2012)
Cell
, vol.151
, pp. 384-399
-
-
Jin, J.1
Sison, K.2
Li, C.3
Tian, R.4
Wnuk, M.5
Sung, H.K.6
Jeansson, M.7
Zhang, C.8
Tucholska, M.9
Jones, N.10
Kerjaschki, D.11
Shibuya, M.12
Fantus, I.G.13
Nagy, A.14
Gerber, H.P.15
Ferrara, N.16
Pawson, T.17
Quaggin, S.E.18
-
54
-
-
84897407234
-
Growth hormone, insulin-like growth factor-1, and the kidney: Patho-physiological and clinical implications
-
Kamenicky P, Mazziotti G, Lombes M, Giustina A, Chanson P. Growth hormone, insulin-like growth factor-1, and the kidney: patho-physiological and clinical implications. Endocr Rev 35: 234–281, 2014.
-
(2014)
Endocr Rev
, vol.35
, pp. 234-281
-
-
Kamenicky, P.1
Mazziotti, G.2
Lombes, M.3
Giustina, A.4
Chanson, P.5
-
55
-
-
79751477368
-
A glimpse of various pathogenetic mechanisms of diabetic nephropathy
-
Kanwar YS, Sun L, Xie P, Liu FY, Chen S. A glimpse of various pathogenetic mechanisms of diabetic nephropathy. Annu Rev Pathol 6: 395–423, 2011.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 395-423
-
-
Kanwar, Y.S.1
Sun, L.2
Xie, P.3
Liu, F.Y.4
Chen, S.5
-
56
-
-
79960932477
-
MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus
-
Karolina DS, Armugam A, Tavintharan S, Wong MT, Lim SC, Sum CF, Jeyaseelan K. MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus. PLoS One 6: e22839, 2011.
-
(2011)
Plos One
, vol.6
-
-
Karolina, D.S.1
Armugam, A.2
Tavintharan, S.3
Wong, M.T.4
Lim, S.C.5
Sum, C.F.6
Jeyaseelan, K.7
-
57
-
-
80052248898
-
A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells
-
Kato M, Arce L, Wang M, Putta S, Lanting L, Natarajan R. A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells. Kidney Int 80: 358–368, 2011.
-
(2011)
Kidney Int
, vol.80
, pp. 358-368
-
-
Kato, M.1
Arce, L.2
Wang, M.3
Putta, S.4
Lanting, L.5
Natarajan, R.6
-
58
-
-
79951973311
-
Preservations of nephrin and synap-topodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice
-
Kato T, Mizuno S, Nakamura T. Preservations of nephrin and synap-topodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice. Nephrology (Carlton) 16: 310–318, 2011.
-
(2011)
Nephrology (Carlton)
, vol.16
, pp. 310-318
-
-
Kato, T.1
Mizuno, S.2
Nakamura, T.3
-
59
-
-
0035040924
-
Endothelin system: The double-edged sword in health and disease
-
Kedzierski RM, Yanagisawa M. Endothelin system: the double-edged sword in health and disease. Annu Rev Pharmacol Toxicol 41: 851–876, 2001.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 851-876
-
-
Kedzierski, R.M.1
Yanagisawa, M.2
-
60
-
-
79951820036
-
Mesangial cell integrin alphavbeta8 provides glomerular endothelial cell cytopro-tection by sequestering TGF-beta and regulating PECAM-1
-
Khan S, Lakhe-Reddy S, McCarty JH, Sorenson CM, Sheibani N, Reichardt LF, Kim JH, Wang B, Sedor JR, Schelling JR. Mesangial cell integrin alphavbeta8 provides glomerular endothelial cell cytopro-tection by sequestering TGF-beta and regulating PECAM-1. Am J Pathol 178: 609–620, 2011.
-
(2011)
Am J Pathol
, vol.178
, pp. 609-620
-
-
Khan, S.1
Lakhe-Reddy, S.2
McCarty, J.H.3
Sorenson, C.M.4
Sheibani, N.5
Reichardt, L.F.6
Kim, J.H.7
Wang, B.8
Sedor, J.R.9
Schelling, J.R.10
-
61
-
-
84879968867
-
Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy
-
Kidokoro K, Satoh M, Channon KM, Yada T, Sasaki T, Kashihara N. Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy. J Am Soc Nephrol 24: 1139–1150, 2013.
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 1139-1150
-
-
Kidokoro, K.1
Satoh, M.2
Channon, K.M.3
Yada, T.4
Sasaki, T.5
Kashihara, N.6
-
62
-
-
0030707954
-
Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
-
Kim HS, Nagalla SR, Oh Y, Wilson E, Roberts CT Jr, Rosenfeld RG. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci USA 94: 12981–12986, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12981-12986
-
-
Kim, H.S.1
Nagalla, S.R.2
Oh, Y.3
Wilson, E.4
Roberts, C.T.5
Rosenfeld, R.G.6
-
63
-
-
56349114070
-
Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells
-
Kokudo T, Suzuki Y, Yoshimatsu Y, Yamazaki T, Watabe T, Miya-zono K. Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells. J Cell Sci 121: 3317–3324, 2008.
-
(2008)
J Cell Sci
, vol.121
, pp. 3317-3324
-
-
Kokudo, T.1
Suzuki, Y.2
Yoshimatsu, Y.3
Yamazaki, T.4
Watabe, T.5
Miya-Zono, K.6
-
64
-
-
0035057565
-
Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes
-
Komers R, Lindsley JN, Oyama TT, Schutzer WE, Reed JF, Mader SL, Anderson S. Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. J Clin Invest 107: 889–898, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 889-898
-
-
Komers, R.1
Lindsley, J.N.2
Oyama, T.T.3
Schutzer, W.E.4
Reed, J.F.5
Mader, S.L.6
Erson, S.7
-
65
-
-
0029953788
-
Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease
-
Kopp JB, Factor VM, Mozes M, Nagy P, Sanderson N, Bottinger EP, Klotman PE, Thorgeirsson SS. Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease. Lab Invest 74: 991–1003, 1996.
-
(1996)
Lab Invest
, vol.74
, pp. 991-1003
-
-
Kopp, J.B.1
Factor, V.M.2
Mozes, M.3
Nagy, P.4
Sanderson, N.5
Bottinger, E.P.6
Klotman, P.E.7
Thorgeirsson, S.S.8
-
66
-
-
77949892330
-
Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy
-
Krupa A, Jenkins R, Luo DD, Lewis A, Phillips A, Fraser D. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. J Am Soc Nephrol 21: 438–447, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 438-447
-
-
Krupa, A.1
Jenkins, R.2
Luo, D.D.3
Lewis, A.4
Phillips, A.5
Fraser, D.6
-
67
-
-
58149343883
-
Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice
-
Ku CH, White KE, Dei Cas A, Hayward A, Webster Z, Bilous R, Marshall S, Viberti G, Gnudi L. Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice. Diabetes 57: 2824–2833, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 2824-2833
-
-
Ku, C.H.1
White, K.E.2
Dei Cas, A.3
Hayward, A.4
Webster, Z.5
Bilous, R.6
Marshall, S.7
Viberti, G.8
Gnudi, L.9
-
68
-
-
79952757250
-
The glomerular podocyte as a target of growth hormone action: Implications for the pathogenesis of diabetic nephropathy
-
Kumar PA, Brosius FC, 3rd, Menon RK. The glomerular podocyte as a target of growth hormone action: implications for the pathogenesis of diabetic nephropathy. Curr Diabetes Rev 7: 50–55, 2011.
-
(2011)
Curr Diabetes Rev
, vol.7
, pp. 50-55
-
-
Kumar, P.A.1
Brosius, F.C.2
Menon, R.K.3
-
69
-
-
84903618700
-
Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk
-
Kuravi SJ, McGettrick HM, Satchell SC, Saleem MA, Harper L, Williams JM, Rainger GE, Savage CO. Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk. J Immunol 193: 234–243, 2014.
-
(2014)
J Immunol
, vol.193
, pp. 234-243
-
-
Kuravi, S.J.1
McGettrick, H.M.2
Satchell, S.C.3
Saleem, M.A.4
Harper, L.5
Williams, J.M.6
Rainger, G.E.7
Savage, C.O.8
-
70
-
-
77955554252
-
Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats
-
Kuwabara A, Satoh M, Tomita N, Sasaki T, Kashihara N. Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats. Diabetologia 53: 2056–2065, 2010.
-
(2010)
Diabetologia
, vol.53
, pp. 2056-2065
-
-
Kuwabara, A.1
Satoh, M.2
Tomita, N.3
Sasaki, T.4
Kashihara, N.5
-
71
-
-
0031658440
-
Nature of glomerular dysfunction in pre-eclampsia
-
Lafayette RA, Druzin M, Sibley R, Derby G, Malik T, Huie P, Polhemus C, Deen WM, Myers BD. Nature of glomerular dysfunction in pre-eclampsia. Kidney Int 54: 1240–1249, 1998.
-
(1998)
Kidney Int
, vol.54
, pp. 1240-1249
-
-
Lafayette, R.A.1
Druzin, M.2
Sibley, R.3
Derby, G.4
Malik, T.5
Huie, P.6
Polhemus, C.7
Deen, W.M.8
Myers, B.D.9
-
72
-
-
0033759171
-
Glomerular permselectivity at the onset of nephropathy in type 2 diabetes mellitus
-
Lemley KV, Blouch K, Abdullah I, Boothroyd DB, Bennett PH, Myers BD, Nelson RG. Glomerular permselectivity at the onset of nephropathy in type 2 diabetes mellitus. J Am Soc Nephrol 11: 2095– 2105, 2000.
-
(2000)
J Am Soc Nephrol
, vol.11
-
-
Lemley, K.V.1
Blouch, K.2
Abdullah, I.3
Boothroyd, D.B.4
Bennett, P.H.5
Myers, B.D.6
Nelson, R.G.7
-
73
-
-
0035199084
-
Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism
-
Li B, Yao J, Morioka T, Oite T. Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism. J Am Soc Nephrol 12: 2616–2624, 2001.
-
(2001)
Jam Soc Nephrol
, vol.12
, pp. 2616-2624
-
-
Li, B.1
Yao, J.2
Morioka, T.3
Oite, T.4
-
74
-
-
73549092294
-
Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice
-
Li J, Qu X, Bertram JF. Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am J Pathol 175: 1380–1388, 2009.
-
(2009)
Am J Pathol
, vol.175
, pp. 1380-1388
-
-
Li, J.1
Qu, X.2
Bertram, J.F.3
-
75
-
-
77957573525
-
Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozo-tocin-induced diabetic nephropathy
-
Li J, Qu X, Yao J, Caruana G, Ricardo SD, Yamamoto Y, Yamamoto H, Bertram JF. Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozo-tocin-induced diabetic nephropathy. Diabetes 59: 2612–2624, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 2612-2624
-
-
Li, J.1
Qu, X.2
Yao, J.3
Caruana, G.4
Ricardo, S.D.5
Yamamoto, Y.6
Yamamoto, H.7
Bertram, J.F.8
-
76
-
-
17044384530
-
Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: Relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis
-
Lim HS, Lip GY, Blann AD. Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis. Atherosclerosis 180: 113–118, 2005.
-
(2005)
Atherosclerosis
, vol.180
, pp. 113-118
-
-
Lim, H.S.1
Lip, G.Y.2
Blann, A.D.3
-
77
-
-
0031668536
-
Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli
-
Lindahl P, Hellstrom M, Kalen M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C. Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development 125: 3313–3322, 1998.
-
(1998)
Development
, vol.125
, pp. 3313-3322
-
-
Lindahl, P.1
Hellstrom, M.2
Kalen, M.M.3
Karlsson, L.4
Pekny, M.5
Pekna, M.6
Soriano, P.7
Betsholtz, C.8
-
78
-
-
34249901258
-
Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy
-
Lindenmeyer MT, Kretzler M, Boucherot A, Berra S, Yasuda Y, Henger A, Eichinger F, Gaiser S, Schmid H, Rastaldi MP, Schrier RW, Schlondorff D, Cohen CD. Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy. J Am Soc Nephrol 18: 1765-1776, 2007.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1765-1776
-
-
Lindenmeyer, M.T.1
Kretzler, M.2
Boucherot, A.3
Berra, S.4
Yasuda, Y.5
Henger, A.6
Eichinger, F.7
Gaiser, S.8
Schmid, H.9
Rastaldi, M.P.10
Schrier, R.W.11
Schlondorff, D.12
Cohen, C.D.13
-
79
-
-
0030475524
-
Vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat
-
Liu Y, Tolbert EM, Sun AM, Dworkin LD. In vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat. Am J Physiol Renal Fluid Electrolyte Physiol 271: F1202-F1210, 1996.
-
(1996)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.271
, pp. F1202-F1210
-
-
Liu, Y.1
Tolbert, E.M.2
Sun, A.M.3
Dworkin, L.D.4
-
80
-
-
79953215711
-
MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy
-
Long J, Wang Y, Wang W, Chang BH, Danesh FR. MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J Biol Chem 286: 11837-11848, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 11837-11848
-
-
Long, J.1
Wang, Y.2
Wang, W.3
Chang, B.H.4
Danesh, F.R.5
-
81
-
-
79955593914
-
MicroRNAs as mediators and therapeutic targets in chronic kidney disease
-
Lorenzen JM, Haller H, Thum T. MicroRNAs as mediators and therapeutic targets in chronic kidney disease. Nat Rev Nephrol 7: 286-294, 2011.
-
(2011)
Nat Rev Nephrol
, vol.7
, pp. 286-294
-
-
Lorenzen, J.M.1
Haller, H.2
Thum, T.3
-
82
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277: 55-60, 1997.
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
83
-
-
18444410236
-
Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist
-
Makino H, Tanaka I, Mukoyama M, Sugawara A, Mori K, Muro S, Suganami T, Yahata K, Ishibashi R, Ohuchida S, Maruyama T, Narumiya S, Nakao K. Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist. J Am Soc Nephrol 13: 1757-1765, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1757-1765
-
-
Makino, H.1
Tanaka, I.2
Mukoyama, M.3
Sugawara, A.4
Mori, K.5
Muro, S.6
Suganami, T.7
Yahata, K.8
Ishibashi, R.9
Ohuchida, S.10
Maruyama, T.11
Narumiya, S.12
Nakao, K.13
-
84
-
-
77949877308
-
Avosentan for overt diabetic nephropathy
-
Mann JF, Green D, Jamerson K, Ruilope LM, Kuranoff SJ, Littke T, Viberti G. Avosentan for overt diabetic nephropathy. J Am Soc Nephrol 21: 527-535, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 527-535
-
-
Mann, J.F.1
Green, D.2
Jamerson, K.3
Ruilope, L.M.4
Kuranoff, S.J.5
Littke, T.6
Viberti, G.7
-
85
-
-
0037373006
-
Excess placental soluble fms-like tyrosine kinase 1 (SFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
-
Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111: 649 -658, 2003.
-
(2003)
J Clin Invest
, vol.111
-
-
Maynard, S.E.1
Min, J.Y.2
Merchan, J.3
Lim, K.H.4
Li, J.5
Mondal, S.6
Libermann, T.A.7
Morgan, J.P.8
Sellke, F.W.9
Stillman, I.E.10
Epstein, F.H.11
Sukhatme, V.P.12
Karumanchi, S.A.13
-
86
-
-
78650159484
-
Endothelialsurface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice
-
Meuwese MC, Broekhuizen LN, Kuikhoven M, Heeneman S, Lut-gens E, Gijbels MJ, Nieuwdorp M, Peutz CJ, Stroes ES, Vink H, van den Berg BM. Endothelial surface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice. PLoS One 5: e14262, 2010.
-
(2010)
Plos One
, pp. 5
-
-
Meuwese, M.C.1
Broekhuizen, L.N.2
Kuikhoven, M.3
Heeneman, S.4
Lut-Gens, E.5
Gijbels, M.J.6
Nieuwdorp, M.7
Peutz, C.J.8
Stroes, E.S.9
Vink, H.10
Van Den Berg, B.M.11
-
87
-
-
0346099296
-
Suppressions of chronic glomerular injuries and TGF-ß1 production by HGF in attenuation of murine diabetic nephropathy
-
Mizuno S, Nakamura T. Suppressions of chronic glomerular injuries and TGF-ß1 production by HGF in attenuation of murine diabetic nephropathy. Am J Physiol Renal Physiol 286: F134-F143, 2004.
-
(2004)
Am J Physiol Renal Physiol
, vol.286
, pp. F134-F143
-
-
Mizuno, S.1
Nakamura, T.2
-
88
-
-
20944437139
-
Response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: Implication for permselective dysfunction of chronic nephropathies
-
Morigi M, Buelli S, Angioletti S, Zanchi C, Longaretti L, Zoja C, Galbusera M, Gastoldi S, Mundel P, Remuzzi G, Benigni A. In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies. Am J Pathol 166: 1309-1320, 2005.
-
(2005)
Am J Pathol
, vol.166
, pp. 1309-1320
-
-
Morigi, M.1
Buelli, S.2
Angioletti, S.3
Zanchi, C.4
Longaretti, L.5
Zoja, C.6
Galbusera, M.7
Gastoldi, S.8
Mundel, P.9
Remuzzi, G.10
Benigni, A.11
-
89
-
-
84874830679
-
Functional implications of microRNA-215 in TGF-beta1-in-duced phenotypic transition of mesangial cells by targeting CTNNBIP1
-
Mu J, Pang Q, Guo YH, Chen JG, Zeng W, Huang YJ, Zhang J, Feng B. Functional implications of microRNA-215 in TGF-beta1-in-duced phenotypic transition of mesangial cells by targeting CTNNBIP1. PLoS One 8: e58622, 2013.
-
(2013)
Plos One
, pp. 8
-
-
Mu, J.1
Pang, Q.2
Guo, Y.H.3
Chen, J.G.4
Zeng, W.5
Huang, Y.J.6
Zhang, J.7
Feng, B.8
-
90
-
-
27144500956
-
Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes
-
Nagareddy PR, Xia Z, McNeill JH, MacLeod KM. Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes. Am J Physiol Heart Circ Physiol 289: H2144-H2152, 2005.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
, pp. H2144-H2152
-
-
Nagareddy, P.R.1
Xia, Z.2
McNeill, J.H.3
Macleod, K.M.4
-
91
-
-
0032422342
-
Hepa-tocyte growth factor as a potential index of complication in diabetes mellitus
-
Nakamura S, Morishita R, Moriguchi A, Yo Y, Nakamura Y, Hayashi S, Matsumoto K, Nakamura T, Higaki J, Ogihara T. Hepa-tocyte growth factor as a potential index of complication in diabetes mellitus. J Hypertens 16: 2019-2026, 1998.
-
(1998)
J Hypertens
, vol.16
, pp. 2019-2026
-
-
Nakamura, S.1
Morishita, R.2
Moriguchi, A.3
Yo, Y.4
Nakamura, Y.5
Hayashi, S.6
Matsumoto, K.7
Nakamura, T.8
Higaki, J.9
Ogihara, T.10
-
92
-
-
33745311155
-
Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes
-
Nieuwdorp M, Mooij HL, Kroon J, Atasever B, Spaan JA, Ince C, Holleman F, Diamant M, Heine RJ, Hoekstra JB, Kastelein JJ, Stroes ES, Vink H. Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes. Diabetes 55: 1127-1132, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 1127-1132
-
-
Nieuwdorp, M.1
Mooij, H.L.2
Kroon, J.3
Atasever, B.4
Spaan, J.A.5
Ince, C.6
Holleman, F.7
Diamant, M.8
Heine, R.J.9
Hoekstra, J.B.10
Kastelein, J.J.11
Stroes, E.S.12
Vink, H.13
-
93
-
-
84859826286
-
Glomerular endothelium: A porous sieve and formidable barrier
-
Obeidat M, Ballermann BJ. Glomerular endothelium: a porous sieve and formidable barrier. Exp Cell Res 318: 964-972, 2012.
-
(2012)
Exp Cell Res
, vol.318
, pp. 964-972
-
-
Obeidat, M.1
Ballermann, B.J.2
-
94
-
-
0031029379
-
Podocyte loss and progressive glomerular injury in type II diabetes
-
Pagtalunan ME, Miller PL, Jumping-Eagle S, Nelson RG, Myers BD, Rennke HG, Coplon NS, Sun L, Meyer TW. Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest 99: 342-348, 1997.
-
(1997)
J Clin Invest
, vol.99
, pp. 342-348
-
-
Pagtalunan, M.E.1
Miller, P.L.2
Jumping-Eagle, S.3
Nelson, R.G.4
Myers, B.D.5
Rennke, H.G.6
Coplon, N.S.7
Sun, L.8
Meyer, T.W.9
-
95
-
-
1242348060
-
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
-
Park M, Dean M, Kaul K, Braun MJ, Gonda MA, Vande Woude G. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci USA 84: 6379-6383, 1987.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6379-6383
-
-
Park, M.1
Dean, M.2
Kaul, K.3
Braun, M.J.4
Gonda, M.A.5
Vande Woude, G.6
-
96
-
-
12344330373
-
Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: Role of the renin-angiotensin system
-
Rizkalla B, Forbes JM, Cao Z, Boner G, Cooper ME. Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system. J Hypertens 23: 153–164, 2005.
-
(2005)
J Hypertens
, vol.23
, pp. 153-164
-
-
Rizkalla, B.1
Forbes, J.M.2
Cao, Z.3
Boner, G.4
Cooper, M.E.5
-
97
-
-
84864858513
-
Loss of the endothelial glycoca-lyx links albuminuria and vascular dysfunction
-
Salmon AH, Ferguson JK, Burford JL, Gevorgyan H, Nakano D, Harper SJ, Bates DO, Peti-Peterdi J. Loss of the endothelial glycoca-lyx links albuminuria and vascular dysfunction. J Am Soc Nephrol 23: 1339–1350, 2012.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1339-1350
-
-
Salmon, A.H.1
Ferguson, J.K.2
Burford, J.L.3
Gevorgyan, H.4
Nakano, D.5
Harper, S.J.6
Bates, D.O.7
Peti-Peterdi, J.8
-
98
-
-
84856708866
-
Endothelial glycocalyx dysfunction in disease: Albuminuria and increased microvascular permeability
-
Salmon AH, Satchell SC. Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability. J Pathol 226: 562–574, 2012.
-
(2012)
J Pathol
, vol.226
, pp. 562-574
-
-
Salmon, A.H.1
Satchell, S.C.2
-
99
-
-
66049109286
-
Glomerular endothelial cell fenestrations: An integral component of the glomerular filtration barrier
-
Satchell SC, Braet F. Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier. Am J Physiol Renal Physiol 296: F947–F956, 2009.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, pp. F947-F956
-
-
Satchell, S.C.1
Braet, F.2
-
100
-
-
41849137193
-
What is the mechanism of microalbuminuria in diabetes: A role for the glomerular endothelium?
-
Satchell SC, Tooke JE. What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium? Diabetologia 51: 714– 725, 2008.
-
(2008)
Diabetologia
, vol.51
-
-
Satchell, S.C.1
Tooke, J.E.2
-
101
-
-
0034836835
-
Apoptosis in podocytes induced by TGF-beta and Smad7
-
Schiffer M, Bitzer M, Roberts IS, Kopp JB, ten Dijke P, Mundel P, Bottinger EP. Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest 108: 807–816, 2001.
-
(2001)
Jclininvest
, vol.108
, pp. 807-816
-
-
Schiffer, M.1
Bitzer, M.2
Roberts, I.S.3
Kopp, J.B.4
Ten Dijke, P.5
Mundel, P.6
Bottinger, E.P.7
-
102
-
-
84899729677
-
Putting the glomerulus back together: Per aspera ad astra (“a rough road leads to the stars”)
-
Schlondorff D. Putting the glomerulus back together: per aspera ad astra (“a rough road leads to the stars”). Kidney Int 85: 991–998, 2014.
-
(2014)
Kidney Int
, vol.85
, pp. 991-998
-
-
Schlondorff, D.1
-
103
-
-
67449083682
-
The mesangial cell revisited: No cell is an island
-
Schlondorff D, Banas B. The mesangial cell revisited: no cell is an island. J Am Soc Nephrol 20: 1179–1187, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1179-1187
-
-
Schlondorff, D.1
Banas, B.2
-
104
-
-
63849233538
-
TGF-beta signal transduction in chronic kidney disease
-
Schnaper HW, Jandeska S, Runyan CE, Hubchak SC, Basu RK, Curley JF, Smith RD, Hayashida T. TGF-beta signal transduction in chronic kidney disease. Front Biosci 14: 2448–2465, 2009.
-
(2009)
Front Biosci
, vol.14
, pp. 2448-2465
-
-
Schnaper, H.W.1
Jandeska, S.2
Runyan, C.E.3
Hubchak, S.C.4
Basu, R.K.5
Curley, J.F.6
Smith, R.D.7
Hayashida, T.8
-
105
-
-
73749083481
-
Global estimates of the prevalence of diabetes for 2010 and 2030
-
Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87: 4–14, 2010.
-
(2010)
Diabetes Res Clin Pract
, vol.87
, pp. 4-14
-
-
Shaw, J.E.1
Sicree, R.A.2
Zimmet, P.Z.3
-
106
-
-
77957861954
-
Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling
-
Sison K, Eremina V, Baelde H, Min W, Hirashima M, Fantus IG, Quaggin SE. Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling. J Am Soc Nephrol 21: 1691–1701, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1691-1701
-
-
Sison, K.1
Eremina, V.2
Baelde, H.3
Min, W.4
Hirashima, M.5
Fantus, I.G.6
Quaggin, S.E.7
-
107
-
-
84862756066
-
Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes
-
Slater SC, Ramnath RD, Uttridge K, Saleem MA, Cahill PA, Ma-thieson PW, Welsh GI, Satchell SC. Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes. Int J Biochem Cell Biol 44: 1482–1490, 2012.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1482-1490
-
-
Slater, S.C.1
Ramnath, R.D.2
Uttridge, K.3
Saleem, M.A.4
Cahill, P.A.5
Ma-Thieson, P.W.6
Welsh, G.I.7
Satchell, S.C.8
-
108
-
-
0027437547
-
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
-
Sonnenberg E, Meyer D, Weidner KM, Birchmeier C. Scatter factor/ hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J Cell Biol 123: 223–235, 1993.
-
(1993)
J Cell Biol
, vol.123
, pp. 223-235
-
-
Sonnenberg, E.1
Meyer, D.2
Weidner, K.M.3
Birchmeier, C.4
-
110
-
-
77957866215
-
A maladaptive role for EP4 receptors in podocytes
-
Stitt-Cavanagh EM, Faour WH, Takami K, Carter A, Vanderhyden B, Guan Y, Schneider A, Breyer MD, Kennedy CR. A maladaptive role for EP4 receptors in podocytes. J Am Soc Nephrol 21: 1678–1690, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1678-1690
-
-
Stitt-Cavanagh, E.M.1
Faour, W.H.2
Takami, K.3
Carter, A.4
Vanderhyden, B.5
Guan, Y.6
Schneider, A.7
Breyer, M.D.8
Kennedy, C.R.9
-
111
-
-
0037631361
-
Neutralization of circulating vascular endothe-lial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria
-
Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R. Neutralization of circulating vascular endothe-lial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem 278: 12605–12608, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 12605-12608
-
-
Sugimoto, H.1
Hamano, Y.2
Charytan, D.3
Cosgrove, D.4
Kieran, M.5
Sudhakar, A.6
Kalluri, R.7
-
112
-
-
84872843610
-
Glomerular endothelial cell injury and damage precedes that of podocytes in adria-mycin-induced nephropathy
-
Sun YB, Qu X, Zhang X, Caruana G, Bertram JF, Li J. Glomerular endothelial cell injury and damage precedes that of podocytes in adria-mycin-induced nephropathy. PLoS One 8: e55027, 2013.
-
(2013)
Plos One
, pp. 8
-
-
Sun, Y.B.1
Qu, X.2
Zhang, X.3
Caruana, G.4
Bertram, J.F.5
Li, J.6
-
113
-
-
33750713086
-
Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice
-
Sung SH, Ziyadeh FN, Wang A, Pyagay PE, Kanwar YS, Chen S. Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice. J Am Soc Nephrol 17: 3093–3104, 2006.
-
(2006)
Jam Soc Nephrol
, vol.17
, pp. 3093-3104
-
-
Sung, S.H.1
Ziyadeh, F.N.2
Wang, A.3
Pyagay, P.E.4
Kanwar, Y.S.5
Chen, S.6
-
114
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87: 1171– 1180, 1996.
-
(1996)
Cell
, vol.87
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
Davis, S.6
Sato, T.N.7
Yancopoulos, G.D.8
-
115
-
-
33644783770
-
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
-
Susztak K, Raff AC, Schiffer M, Bottinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55: 225–233, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 225-233
-
-
Susztak, K.1
Raff, A.C.2
Schiffer, M.3
Bottinger, E.P.4
-
116
-
-
0027631720
-
Transcriptional activation of matrix genes by transforming growth factor beta 1 in mesangial cells
-
Suzuki S, Ebihara I, Tomino Y, Koide H. Transcriptional activation of matrix genes by transforming growth factor beta 1 in mesangial cells. Exp Nephrol 1: 229–237, 1993.
-
(1993)
Exp Nephrol
, vol.1
, pp. 229-237
-
-
Suzuki, S.1
Ebihara, I.2
Tomino, Y.3
Koide, H.4
-
117
-
-
68049123542
-
The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature
-
Takabatake Y, Sugiyama T, Kohara H, Matsusaka T, Kurihara H, Koni PA, Nagasawa Y, Hamano T, Matsui I, Kawada N, Imai E, Nagasawa T, Rakugi H, Isaka Y. The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature. J Am Soc Nephrol 20: 1714–1723, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1714-1723
-
-
Takabatake, Y.1
Sugiyama, T.2
Kohara, H.3
Matsusaka, T.4
Kurihara, H.5
Koni, P.A.6
Nagasawa, Y.7
Hamano, T.8
Matsui, I.9
Kawada, N.10
Imai, E.11
Nagasawa, T.12
Rakugi, H.13
Isaka, Y.14
-
118
-
-
58149192157
-
The endothelial glycocalyx: A mechano-sensor and -transducer
-
Tarbell JM, Ebong EE. The endothelial glycocalyx: a mechano-sensor and -transducer. Sci Signal 1: pt8, 2008.
-
(2008)
Sci Signal
, vol.1
-
-
Tarbell, J.M.1
Ebong, E.E.2
-
119
-
-
0034036689
-
Angiopoietin-1 protects the adult vasculature against plasma leakage
-
Thurston G, Rudge JS, Ioffe E, Zhou H, Ross L, Croll SD, Glazer N, Holash J, McDonald DM, Yancopoulos GD. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 6: 460–463, 2000.
-
(2000)
Nat Med
, vol.6
, pp. 460-463
-
-
Thurston, G.1
Rudge, J.S.2
Ioffe, E.3
Zhou, H.4
Ross, L.5
Croll, S.D.6
Glazer, N.7
Holash, J.8
McDonald, D.M.9
Yancopoulos, G.D.10
-
120
-
-
78149298673
-
Induction of podocyte VEGF164 overexpres-sion at different stages of development causes congenital nephrosis or steroid-resistant nephrotic syndrome
-
Veron D, Reidy K, Marlier A, Bertuccio C, Villegas G, Jimenez J, Kashgarian M, Tufro A. Induction of podocyte VEGF164 overexpres-sion at different stages of development causes congenital nephrosis or steroid-resistant nephrotic syndrome. Am J Pathol 177: 2225–2233, 2010.
-
(2010)
Am J Pathol
, vol.177
, pp. 2225-2233
-
-
Veron, D.1
Reidy, K.2
Marlier, A.3
Bertuccio, C.4
Villegas, G.5
Jimenez, J.6
Kashgarian, M.7
Tufro, A.8
-
121
-
-
77955870854
-
Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease
-
Veron D, Reidy KJ, Bertuccio C, Teichman J, Villegas G, Jimenez J, Shen W, Kopp JB, Thomas DB, Tufro A. Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease. Kidney Int 77: 989–999, 2010.
-
(2010)
Kidney Int
, vol.77
, pp. 989-999
-
-
Veron, D.1
Reidy, K.J.2
Bertuccio, C.3
Teichman, J.4
Villegas, G.5
Jimenez, J.6
Shen, W.7
Kopp, J.B.8
Thomas, D.B.9
Tufro, A.10
-
122
-
-
84867576816
-
Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy
-
Weil EJ, Lemley KV, Mason CC, Yee B, Jones LI, Blouch K, Lovato T, Richardson M, Myers BD, Nelson RG. Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy. Kidney Int 82: 1010–1017, 2012.
-
(2012)
Kidney Int
, vol.82
, pp. 1010-1017
-
-
Weil, E.J.1
Lemley, K.V.2
Mason, C.C.3
Yee, B.4
Jones, L.I.5
Blouch, K.6
Lovato, T.7
Richardson, M.8
Myers, B.D.9
Nelson, R.G.10
-
123
-
-
16844383687
-
Diabetic nephropathy: The proteinuria hypothesis
-
Williams ME. Diabetic nephropathy: the proteinuria hypothesis. Am J Nephrol 25: 77–94, 2005.
-
(2005)
Am J Nephrol
, vol.25
, pp. 77-94
-
-
Williams, M.E.1
-
124
-
-
59949085812
-
Roles of angiopoietins in kidney development and disease
-
Woolf AS, Gnudi L, Long DA. Roles of angiopoietins in kidney development and disease. J Am Soc Nephrol 20: 239–244, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 239-244
-
-
Woolf, A.S.1
Gnudi, L.2
Long, D.A.3
-
125
-
-
33644877366
-
TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes
-
Wu DT, Bitzer M, Ju W, Mundel P, Bottinger EP. TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes. J Am Soc Nephrol 16: 3211–3221, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3211-3221
-
-
Wu, D.T.1
Bitzer, M.2
Ju, W.3
Mundel, P.4
Bottinger, E.P.5
-
126
-
-
68049102222
-
TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho-and myosin light chain kinase-dependent mechanism
-
Wu X, Guo R, Chen P, Wang Q, Cunningham PN. TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho-and myosin light chain kinase-dependent mechanism. Am J Physiol Renal Physiol 297: F316–F326, 2009.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F316-F326
-
-
Wu, X.1
Guo, R.2
Chen, P.3
Wang, Q.4
Cunningham, P.N.5
-
127
-
-
84891555200
-
TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis
-
Xu C, Chang A, Hack BK, Eadon MT, Alper SL, Cunningham PN. TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis. Kidney Int 85: 72–81, 2014.
-
(2014)
Kidney Int
, vol.85
, pp. 72-81
-
-
Xu, C.1
Chang, A.2
Hack, B.K.3
Eadon, M.T.4
Alper, S.L.5
Cunningham, P.N.6
-
128
-
-
33644746320
-
The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice
-
Xu S, Jiang B, Maitland KA, Bayat H, Gu J, Nadler JL, Corda S, Lavielle G, Verbeuren TJ, Zuccollo A, Cohen RA. The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice. Diabetes 55: 110–119, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 110-119
-
-
Xu, S.1
Jiang, B.2
Maitland, K.A.3
Bayat, H.4
Gu, J.5
Nadler, J.L.6
Corda, S.7
Lavielle, G.8
Verbeuren, T.J.9
Zuccollo, A.10
Cohen, R.A.11
-
129
-
-
3042739353
-
Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy
-
Yamamoto Y, Maeshima Y, Kitayama H, Kitamura S, Takazawa Y, Sugiyama H, Yamasaki Y, Makino H. Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy. Diabetes 53: 1831–1840, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 1831-1840
-
-
Yamamoto, Y.1
Maeshima, Y.2
Kitayama, H.3
Kitamura, S.4
Takazawa, Y.5
Sugiyama, H.6
Yamasaki, Y.7
Makino, H.8
-
130
-
-
0036138824
-
Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis
-
Yang J, Liu Y. Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis. J Am Soc Nephrol 13: 96–107, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 96-107
-
-
Yang, J.1
Liu, Y.2
-
131
-
-
36849053415
-
Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt
-
Yano T, Liu Z, Donovan J, Thomas MK, Habener JF. Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt. Diabetes 56: 2946–2957, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 2946-2957
-
-
Yano, T.1
Liu, Z.2
Donovan, J.3
Thomas, M.K.4
Habener, J.F.5
-
132
-
-
0027450159
-
Transforming growth factor-beta protein and mRNA in glomeruli in normal and diseased human kidneys
-
Yoshioka K, Takemura T, Murakami K, Okada M, Hino S, Miyamoto H, Maki S. Transforming growth factor-beta protein and mRNA in glomeruli in normal and diseased human kidneys. Lab Invest 68: 154–163, 1993.
-
(1993)
Lab Invest
, vol.68
, pp. 154-163
-
-
Yoshioka, K.1
Takemura, T.2
Murakami, K.3
Okada, M.4
Hino, S.5
Miyamoto, H.6
Maki, S.7
-
133
-
-
0026233110
-
Reactive oxygen metabolites cause massive, reversible proteinuria and glomerular sieving defect without apparent ultrastructural abnormality
-
Yoshioka T, Ichikawa I, Fogo A. Reactive oxygen metabolites cause massive, reversible proteinuria and glomerular sieving defect without apparent ultrastructural abnormality. J Am Soc Nephrol 2: 902–912, 1991.
-
(1991)
J Am Soc Nephrol
, vol.2
, pp. 902-912
-
-
Yoshioka, T.1
Ichikawa, I.2
Fogo, A.3
-
134
-
-
84868628539
-
ENOS deficiency predisposes podocytes to injury in diabetes
-
Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A. eNOS deficiency predisposes podocytes to injury in diabetes. J Am Soc Nephrol 23: 1810–1823, 2012.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1810-1823
-
-
Yuen, D.A.1
Stead, B.E.2
Zhang, Y.3
White, K.E.4
Kabir, M.G.5
Thai, K.6
Advani, S.L.7
Connelly, K.A.8
Takano, T.9
Zhu, L.10
Cox, A.J.11
Kelly, D.J.12
Gibson, I.W.13
Takahashi, T.14
Harris, R.C.15
Advani, A.16
-
135
-
-
0033917346
-
Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism
-
Zanchi A, Moczulski DK, Hanna LS, Wantman M, Warram JH, Krolewski AS. Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism. Kidney Int 57: 405–413, 2000.
-
(2000)
Kidney Int
, vol.57
, pp. 405-413
-
-
Zanchi, A.1
Moczulski, D.K.2
Hanna, L.S.3
Wantman, M.4
Warram, J.H.5
Krolewski, A.S.6
-
136
-
-
55249103431
-
Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition
-
Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol 19: 2282–2287, 2008.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2282-2287
-
-
Zeisberg, E.M.1
Potenta, S.E.2
Sugimoto, H.3
Zeisberg, M.4
Kalluri, R.5
-
137
-
-
34547676391
-
Endothelial-to-mesen-chymal transition contributes to cardiac fibrosis
-
Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R. Endothelial-to-mesen-chymal transition contributes to cardiac fibrosis. Nat Med 13: 952–961, 2007.
-
(2007)
Nat Med
, vol.13
, pp. 952-961
-
-
Zeisberg, E.M.1
Tarnavski, O.2
Zeisberg, M.3
Dorfman, A.L.4
McMullen, J.R.5
Gustafsson, E.6
Chandraker, A.7
Yuan, X.8
Pu, W.T.9
Roberts, A.B.10
Neilson, E.G.11
Sayegh, M.H.12
Izumo, S.13
Kalluri, R.14
-
138
-
-
84922868587
-
Reduced Kruppel-like factor 2 expression may aggravate the endothelial injury of diabetic nephropathy
-
Epub ahead of print
-
Zhong F, Chen H, Wei C, Zhang W, Li Z, Jain MK, Chuang PY, Wang Y, Mallipattu SK, He JC. Reduced Kruppel-like factor 2 expression may aggravate the endothelial injury of diabetic nephropathy. Kidney Int [Epub ahead of print].
-
Kidney Int
-
-
Zhong, F.1
Chen, H.2
Wei, C.3
Zhang, W.4
Li, Z.5
Jain, M.K.6
Chuang, P.Y.7
Wang, Y.8
Mallipattu, S.K.9
He, J.C.10
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