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Volumn 308, Issue 4, 2015, Pages F287-F297

Glomerular endothelial cell injury and cross talk in diabetic kidney disease

Author keywords

Angiopoietin; Diabetes; Endothelial cells; Endothelial nitric oxide; Endothelial surface layer; Endothelin 1; Fenestrate; Glomerular filtration barrier; Glycocalyx; Hepatocyte growth factor; Insulin like growth factor; MicroRNA; Prostanoids; Proteoglycans; Vascular endothelial growth factor

Indexed keywords

ALPHAVBETA8 INTEGRIN; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; CHEMOKINE RECEPTOR CXCR4; CYCLOOXYGENASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; INTEGRIN; INTERLEUKIN 6; KRUPPEL LIKE FACTOR 2; MICRORNA; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTANOID; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; THROMBOXANE B2; THROMBOXANE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; SIGNAL PEPTIDE;

EID: 84994098499     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00533.2014     Document Type: Review
Times cited : (217)

References (138)
  • 2
    • 84928614493 scopus 로고    scopus 로고
    • Insulin-like growth factors and kidney disease
    • Epub before print
    • Bach LA, Hale LJ. Insulin-like growth factors and kidney disease. Am J Kidney Dis [Epub before print].
    • Am J Kidney Dis
    • Bach, L.A.1    Hale, L.J.2
  • 3
    • 81155123707 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes
    • Bertuccio C, Veron D, Aggarwal PK, Holzman L, Tufro A. Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. J Biol Chem 286: 39933– 39944, 2011.
    • (2011) J Biol Chem , vol.286
    • Bertuccio, C.1    Veron, D.2    Aggarwal, P.K.3    Holzman, L.4    Tufro, A.5
  • 5
    • 0035132560 scopus 로고    scopus 로고
    • Familial nephropathy differing from minimal change nephropathy and focal glomerulosclerosis
    • Branten AJ, van den Born J, Jansen JL, Assmann KJ, Wetzels JF. Familial nephropathy differing from minimal change nephropathy and focal glomerulosclerosis. Kidney Int 59: 693–701, 2001.
    • (2001) Kidney Int , vol.59 , pp. 693-701
    • Branten, A.J.1    Van Den Born, J.2    Jansen, J.L.3    Assmann, K.J.4    Wetzels, J.F.5
  • 7
    • 80053377598 scopus 로고    scopus 로고
    • Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glo-merular podocytes
    • Bu X, Zhou Y, Zhang H, Qiu W, Chen L, Cao H, Fang L, Wen P, Tan R, Yang J. Systemic administration of naked plasmid encoding HGF attenuates puromycin aminonucleoside-induced damage of murine glo-merular podocytes. Am J Physiol Renal Physiol 301: F784–F792, 2011.
    • (2011) Am J Physiol Renal Physiol , vol.301 , pp. F784-F792
    • Bu, X.1    Zhou, Y.2    Zhang, H.3    Qiu, W.4    Chen, L.5    Cao, H.6    Fang, L.7    Wen, P.8    Tan, R.9    Yang, J.10
  • 10
    • 12344324985 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is increased during early stage of diabetic nephropathy in type II diabetic rats
    • Cha DR, Kang YS, Han SY, Jee YH, Han KH, Han JY, Kim YS, Kim NH. Vascular endothelial growth factor is increased during early stage of diabetic nephropathy in type II diabetic rats. J Endocrinol 183: 183–194, 2004.
    • (2004) J Endocrinol , vol.183 , pp. 183-194
    • Cha, D.R.1    Kang, Y.S.2    Han, S.Y.3    Jee, Y.4    Han, Y.H.5    Han, J.Y.6    Kim, Y.S.7    Kim, N.H.8
  • 12
    • 7044260750 scopus 로고    scopus 로고
    • Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes
    • Chen S, Kasama Y, Lee JS, Jim B, Marin M, Ziyadeh FN. Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes. Diabetes 53: 2939–2949, 2004.
    • (2004) Diabetes , vol.53 , pp. 2939-2949
    • Chen, S.1    Kasama, Y.2    Lee, J.S.3    Jim, B.4    Marin, M.5    Ziyadeh, F.N.6
  • 14
    • 0036423877 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension
    • Cheng HF, Wang CJ, Moeckel GW, Zhang MZ, McKanna JA, Harris RC. Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension. Kidney Int 62: 929–939, 2002.
    • (2002) Kidney Int , vol.62 , pp. 929-939
    • Cheng, H.F.1    Wang, C.J.2    Moeckel, G.W.3    Zhang, M.Z.4    McKanna, J.A.5    Harris, R.C.6
  • 15
    • 84995821720 scopus 로고
    • Partition of insulin-like growth factor (IGF)-binding sites between the IGF-I and IGF-II receptors and IGF-binding proteins in the human kidney
    • Chin E, Michels K, Bondy CA. Partition of insulin-like growth factor (IGF)-binding sites between the IGF-I and IGF-II receptors and IGF-binding proteins in the human kidney. J Clin Endocrinol Metab 78: 156–164, 1994.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 156-164
    • Chin, E.1    MicHels, K.2    Bondy, C.A.3
  • 17
    • 78651252297 scopus 로고    scopus 로고
    • Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome
    • Clement LC, Avila-Casado C, Mace C, Soria E, Bakker WW, Kersten S, Chugh SS. Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med 17: 117–122, 2011.
    • (2011) Nat Med , vol.17 , pp. 117-122
    • Clement, L.C.1    Avila-Casado, C.2    MaCe, C.3    Soria, E.4    Bakker, W.W.5    Kersten, S.6    Chugh, S.S.7
  • 21
    • 77955877135 scopus 로고    scopus 로고
    • Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria
    • Dai C, Saleem MA, Holzman LB, Mathieson P, Liu Y. Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int 77: 962–973, 2010.
    • (2010) Kidney Int , vol.77 , pp. 962-973
    • Dai, C.1    Saleem, M.A.2    Holzman, L.B.3    Mathieson, P.4    Liu, Y.5
  • 22
    • 15844397902 scopus 로고    scopus 로고
    • Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropa-thy in mice
    • Dai C, Yang J, Bastacky S, Xia J, Li Y, Liu Y. Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropa-thy in mice. J Am Soc Nephrol 15: 2637–2647, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2637-2647
    • Dai, C.1    Yang, J.2    Bastacky, S.3    Xia, J.4    Li, Y.5    Liu, Y.6
  • 24
    • 77957147501 scopus 로고    scopus 로고
    • TGFbeta enforces activation of eukaryotic elongation factor-2 (EEF2) via inacti-vation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy
    • Das F, Ghosh-Choudhury N, Kasinath BS, Choudhury GG. TGFbeta enforces activation of eukaryotic elongation factor-2 (eEF2) via inacti-vation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy. FEBS Lett 584: 4268–4272, 2010.
    • (2010) FEBS Lett , vol.584 , pp. 4268-4272
    • Das, F.1    Ghosh-Choudhury, N.2    Kasinath, B.S.3    Choudhury, G.G.4
  • 26
    • 0027461162 scopus 로고
    • Size- and charge selectivity of glomerular filtration in Type 1 (Insulin-dependent) diabetic patients with and without albuminuria
    • Deckert T, Kofoed-Enevoldsen A, Vidal P, Norgaard K, Andreasen HB, and Feldt-Rasmussen B. Size- and charge selectivity of glomerular filtration in Type 1 (insulin-dependent) diabetic patients with and without albuminuria. Diabetologia 36: 244–251, 1993.
    • (1993) Diabetologia , vol.36 , pp. 244-251
    • Deckert, T.1    Kofoed-Enevoldsen, A.2    Vidal, P.3    Norgaard, K.4    Andreasen, H.B.5    Feldt-Rasmussen, B.6
  • 27
    • 84907520196 scopus 로고    scopus 로고
    • Signaling pathway cooperation in TGF-beta-induced epithelial-mesenchymal transition
    • Derynck R, Muthusamy BP, Saeteurn KY. Signaling pathway cooperation in TGF-beta-induced epithelial-mesenchymal transition. Curr Opin Cell Biol 31: 56–66, 2014.
    • (2014) Curr Opin Cell Biol , vol.31 , pp. 56-66
    • Derynck, R.1    Muthusamy, B.P.2    Saeteurn, K.Y.3
  • 29
    • 0035034655 scopus 로고    scopus 로고
    • Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes
    • de Vriese AS, Tilton RG, Elger M, Stephan CC, Kriz W, Lameire NH. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol 12: 993–1000, 2001.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 993-1000
    • De Vriese, A.S.1    Tilton, R.G.2    Elger, M.3    Stephan, C.C.4    Kriz, W.5    Lameire, N.H.6
  • 32
    • 0344389419 scopus 로고    scopus 로고
    • Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury
    • Dworkin LD, Gong R, Tolbert E, Centracchio J, Yano N, Zanabli AR, Esparza A, Rifai A. Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury. Kidney Int 65: 409–419, 2004.
    • (2004) Kidney Int , vol.65 , pp. 409-419
    • Dworkin, L.D.1    Gong, R.2    Tolbert, E.3    Centracchio, J.4    Yano, N.5    Zanabli, A.R.6    Esparza, A.7    Rifai, A.8
  • 35
    • 38149107161 scopus 로고    scopus 로고
    • A new look at platelet-derived growth factor in renal disease
    • Floege J, Eitner F, Alpers CE. A new look at platelet-derived growth factor in renal disease. J Am Soc Nephrol 19: 12–23, 2008.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 12-23
    • Floege, J.1    Eitner, F.2    Alpers, C.E.3
  • 36
    • 0036789207 scopus 로고    scopus 로고
    • Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody
    • Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R. Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody. Diabetes 51: 3090–3094, 2002.
    • (2002) Diabetes , vol.51 , pp. 3090-3094
    • Flyvbjerg, A.1    Dagnaes-Hansen, F.2    De Vriese, A.S.3    Schrijvers, B.F.4    Tilton, R.G.5    Rasch, R.6
  • 37
    • 77955097036 scopus 로고    scopus 로고
    • The glomerulus–a view from the inside–the endothe-lial cell
    • Fogo AB, Kon V. The glomerulus–a view from the inside–the endothe-lial cell. Int J Biochem Cell Biol 42: 1388–1397, 2010.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1388-1397
    • Fogo, A.B.1    Kon, V.2
  • 38
    • 0035142883 scopus 로고    scopus 로고
    • Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis
    • Fornoni A, Li H, Foschi A, Striker GE, Striker LJ. Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis. Am J Pathol 158: 275–280, 2001.
    • (2001) Am J Pathol , vol.158 , pp. 275-280
    • Fornoni, A.1    Li, H.2    Foschi, A.3    Striker, G.E.4    Striker, L.J.5
  • 41
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and eph-rins in vascular development
    • Gale NW, Yancopoulos GD. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and eph-rins in vascular development. Genes Dev 13: 1055–1066, 1999.
    • (1999) Genes Dev , vol.13 , pp. 1055-1066
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 43
    • 84864397281 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of diabetic glomerulopa-thy
    • Gnudi L. Cellular and molecular mechanisms of diabetic glomerulopa-thy. Nephrol Dial Transplant 27: 2642–2649, 2012.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 2642-2649
    • Gnudi, L.1
  • 44
    • 33746610964 scopus 로고    scopus 로고
    • Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP
    • Guan F, Villegas G, Teichman J, Mundel P, Tufro A. Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP. Am J Physiol Renal Physiol 291: F422–F428, 2006.
    • (2006) Am J Physiol Renal Physiol , vol.291 , pp. F422-F428
    • Guan, F.1    Villegas, G.2    Teichman, J.3    Mundel, P.4    Tufro, A.5
  • 46
    • 42149122041 scopus 로고    scopus 로고
    • Properties of the glomerular barrier and mechanisms of proteinuria
    • Haraldsson B, Nystrom J, Deen WM. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88: 451–487, 2008.
    • (2008) Physiol Rev , vol.88 , pp. 451-487
    • Haraldsson, B.1    Nystrom, J.2    Deen, W.M.3
  • 47
    • 84891499916 scopus 로고    scopus 로고
    • The endothelium as part of the integrative glomerular barrier complex
    • Haraldsson BS. The endothelium as part of the integrative glomerular barrier complex. Kidney Int 85: 8–11, 2014.
    • (2014) Kidney Int , vol.85 , pp. 8-11
    • Haraldsson, B.S.1
  • 49
    • 0346728703 scopus 로고    scopus 로고
    • Electron microscopic evaluation of the endothelial surface layer of glomerular capillaries
    • Hjalmarsson C, Johansson BR, Haraldsson B. Electron microscopic evaluation of the endothelial surface layer of glomerular capillaries. Microvasc Res 67: 9–17, 2004.
    • (2004) Microvasc Res , vol.67 , pp. 9-17
    • Hjalmarsson, C.1    Johansson, B.R.2    Haraldsson, B.3
  • 51
  • 52
    • 33644806727 scopus 로고    scopus 로고
    • Morphological and functional evidence for an important role of the endothelial cell glycocalyx in the glomerular barrier
    • Jeansson M, Haraldsson B. Morphological and functional evidence for an important role of the endothelial cell glycocalyx in the glomerular barrier. Am J Physiol Renal Physiol 290: F111–F116, 2006.
    • (2006) Am J Physiol Renal Physiol , vol.290 , pp. F111-F116
    • Jeansson, M.1    Haraldsson, B.2
  • 54
    • 84897407234 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factor-1, and the kidney: Patho-physiological and clinical implications
    • Kamenicky P, Mazziotti G, Lombes M, Giustina A, Chanson P. Growth hormone, insulin-like growth factor-1, and the kidney: patho-physiological and clinical implications. Endocr Rev 35: 234–281, 2014.
    • (2014) Endocr Rev , vol.35 , pp. 234-281
    • Kamenicky, P.1    Mazziotti, G.2    Lombes, M.3    Giustina, A.4    Chanson, P.5
  • 55
    • 79751477368 scopus 로고    scopus 로고
    • A glimpse of various pathogenetic mechanisms of diabetic nephropathy
    • Kanwar YS, Sun L, Xie P, Liu FY, Chen S. A glimpse of various pathogenetic mechanisms of diabetic nephropathy. Annu Rev Pathol 6: 395–423, 2011.
    • (2011) Annu Rev Pathol , vol.6 , pp. 395-423
    • Kanwar, Y.S.1    Sun, L.2    Xie, P.3    Liu, F.Y.4    Chen, S.5
  • 56
    • 79960932477 scopus 로고    scopus 로고
    • MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus
    • Karolina DS, Armugam A, Tavintharan S, Wong MT, Lim SC, Sum CF, Jeyaseelan K. MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus. PLoS One 6: e22839, 2011.
    • (2011) Plos One , vol.6
    • Karolina, D.S.1    Armugam, A.2    Tavintharan, S.3    Wong, M.T.4    Lim, S.C.5    Sum, C.F.6    Jeyaseelan, K.7
  • 57
    • 80052248898 scopus 로고    scopus 로고
    • A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells
    • Kato M, Arce L, Wang M, Putta S, Lanting L, Natarajan R. A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells. Kidney Int 80: 358–368, 2011.
    • (2011) Kidney Int , vol.80 , pp. 358-368
    • Kato, M.1    Arce, L.2    Wang, M.3    Putta, S.4    Lanting, L.5    Natarajan, R.6
  • 58
    • 79951973311 scopus 로고    scopus 로고
    • Preservations of nephrin and synap-topodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice
    • Kato T, Mizuno S, Nakamura T. Preservations of nephrin and synap-topodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice. Nephrology (Carlton) 16: 310–318, 2011.
    • (2011) Nephrology (Carlton) , vol.16 , pp. 310-318
    • Kato, T.1    Mizuno, S.2    Nakamura, T.3
  • 59
    • 0035040924 scopus 로고    scopus 로고
    • Endothelin system: The double-edged sword in health and disease
    • Kedzierski RM, Yanagisawa M. Endothelin system: the double-edged sword in health and disease. Annu Rev Pharmacol Toxicol 41: 851–876, 2001.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 851-876
    • Kedzierski, R.M.1    Yanagisawa, M.2
  • 61
    • 84879968867 scopus 로고    scopus 로고
    • Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy
    • Kidokoro K, Satoh M, Channon KM, Yada T, Sasaki T, Kashihara N. Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathy. J Am Soc Nephrol 24: 1139–1150, 2013.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1139-1150
    • Kidokoro, K.1    Satoh, M.2    Channon, K.M.3    Yada, T.4    Sasaki, T.5    Kashihara, N.6
  • 62
    • 0030707954 scopus 로고    scopus 로고
    • Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
    • Kim HS, Nagalla SR, Oh Y, Wilson E, Roberts CT Jr, Rosenfeld RG. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci USA 94: 12981–12986, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12981-12986
    • Kim, H.S.1    Nagalla, S.R.2    Oh, Y.3    Wilson, E.4    Roberts, C.T.5    Rosenfeld, R.G.6
  • 63
    • 56349114070 scopus 로고    scopus 로고
    • Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells
    • Kokudo T, Suzuki Y, Yoshimatsu Y, Yamazaki T, Watabe T, Miya-zono K. Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells. J Cell Sci 121: 3317–3324, 2008.
    • (2008) J Cell Sci , vol.121 , pp. 3317-3324
    • Kokudo, T.1    Suzuki, Y.2    Yoshimatsu, Y.3    Yamazaki, T.4    Watabe, T.5    Miya-Zono, K.6
  • 68
    • 79952757250 scopus 로고    scopus 로고
    • The glomerular podocyte as a target of growth hormone action: Implications for the pathogenesis of diabetic nephropathy
    • Kumar PA, Brosius FC, 3rd, Menon RK. The glomerular podocyte as a target of growth hormone action: implications for the pathogenesis of diabetic nephropathy. Curr Diabetes Rev 7: 50–55, 2011.
    • (2011) Curr Diabetes Rev , vol.7 , pp. 50-55
    • Kumar, P.A.1    Brosius, F.C.2    Menon, R.K.3
  • 70
    • 77955554252 scopus 로고    scopus 로고
    • Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats
    • Kuwabara A, Satoh M, Tomita N, Sasaki T, Kashihara N. Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats. Diabetologia 53: 2056–2065, 2010.
    • (2010) Diabetologia , vol.53 , pp. 2056-2065
    • Kuwabara, A.1    Satoh, M.2    Tomita, N.3    Sasaki, T.4    Kashihara, N.5
  • 73
    • 0035199084 scopus 로고    scopus 로고
    • Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism
    • Li B, Yao J, Morioka T, Oite T. Nitric oxide increases albumin permeability of isolated rat glomeruli via a phosphorylation-dependent mechanism. J Am Soc Nephrol 12: 2616–2624, 2001.
    • (2001) Jam Soc Nephrol , vol.12 , pp. 2616-2624
    • Li, B.1    Yao, J.2    Morioka, T.3    Oite, T.4
  • 74
    • 73549092294 scopus 로고    scopus 로고
    • Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice
    • Li J, Qu X, Bertram JF. Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am J Pathol 175: 1380–1388, 2009.
    • (2009) Am J Pathol , vol.175 , pp. 1380-1388
    • Li, J.1    Qu, X.2    Bertram, J.F.3
  • 75
    • 77957573525 scopus 로고    scopus 로고
    • Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozo-tocin-induced diabetic nephropathy
    • Li J, Qu X, Yao J, Caruana G, Ricardo SD, Yamamoto Y, Yamamoto H, Bertram JF. Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozo-tocin-induced diabetic nephropathy. Diabetes 59: 2612–2624, 2010.
    • (2010) Diabetes , vol.59 , pp. 2612-2624
    • Li, J.1    Qu, X.2    Yao, J.3    Caruana, G.4    Ricardo, S.D.5    Yamamoto, Y.6    Yamamoto, H.7    Bertram, J.F.8
  • 76
    • 17044384530 scopus 로고    scopus 로고
    • Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: Relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis
    • Lim HS, Lip GY, Blann AD. Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis. Atherosclerosis 180: 113–118, 2005.
    • (2005) Atherosclerosis , vol.180 , pp. 113-118
    • Lim, H.S.1    Lip, G.Y.2    Blann, A.D.3
  • 79
    • 0030475524 scopus 로고    scopus 로고
    • Vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat
    • Liu Y, Tolbert EM, Sun AM, Dworkin LD. In vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat. Am J Physiol Renal Fluid Electrolyte Physiol 271: F1202-F1210, 1996.
    • (1996) Am J Physiol Renal Fluid Electrolyte Physiol , vol.271 , pp. F1202-F1210
    • Liu, Y.1    Tolbert, E.M.2    Sun, A.M.3    Dworkin, L.D.4
  • 80
    • 79953215711 scopus 로고    scopus 로고
    • MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy
    • Long J, Wang Y, Wang W, Chang BH, Danesh FR. MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J Biol Chem 286: 11837-11848, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 11837-11848
    • Long, J.1    Wang, Y.2    Wang, W.3    Chang, B.H.4    Danesh, F.R.5
  • 81
    • 79955593914 scopus 로고    scopus 로고
    • MicroRNAs as mediators and therapeutic targets in chronic kidney disease
    • Lorenzen JM, Haller H, Thum T. MicroRNAs as mediators and therapeutic targets in chronic kidney disease. Nat Rev Nephrol 7: 286-294, 2011.
    • (2011) Nat Rev Nephrol , vol.7 , pp. 286-294
    • Lorenzen, J.M.1    Haller, H.2    Thum, T.3
  • 87
    • 0346099296 scopus 로고    scopus 로고
    • Suppressions of chronic glomerular injuries and TGF-ß1 production by HGF in attenuation of murine diabetic nephropathy
    • Mizuno S, Nakamura T. Suppressions of chronic glomerular injuries and TGF-ß1 production by HGF in attenuation of murine diabetic nephropathy. Am J Physiol Renal Physiol 286: F134-F143, 2004.
    • (2004) Am J Physiol Renal Physiol , vol.286 , pp. F134-F143
    • Mizuno, S.1    Nakamura, T.2
  • 89
    • 84874830679 scopus 로고    scopus 로고
    • Functional implications of microRNA-215 in TGF-beta1-in-duced phenotypic transition of mesangial cells by targeting CTNNBIP1
    • Mu J, Pang Q, Guo YH, Chen JG, Zeng W, Huang YJ, Zhang J, Feng B. Functional implications of microRNA-215 in TGF-beta1-in-duced phenotypic transition of mesangial cells by targeting CTNNBIP1. PLoS One 8: e58622, 2013.
    • (2013) Plos One , pp. 8
    • Mu, J.1    Pang, Q.2    Guo, Y.H.3    Chen, J.G.4    Zeng, W.5    Huang, Y.J.6    Zhang, J.7    Feng, B.8
  • 90
    • 27144500956 scopus 로고    scopus 로고
    • Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes
    • Nagareddy PR, Xia Z, McNeill JH, MacLeod KM. Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes. Am J Physiol Heart Circ Physiol 289: H2144-H2152, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H2144-H2152
    • Nagareddy, P.R.1    Xia, Z.2    McNeill, J.H.3    Macleod, K.M.4
  • 93
    • 84859826286 scopus 로고    scopus 로고
    • Glomerular endothelium: A porous sieve and formidable barrier
    • Obeidat M, Ballermann BJ. Glomerular endothelium: a porous sieve and formidable barrier. Exp Cell Res 318: 964-972, 2012.
    • (2012) Exp Cell Res , vol.318 , pp. 964-972
    • Obeidat, M.1    Ballermann, B.J.2
  • 95
    • 1242348060 scopus 로고
    • Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
    • Park M, Dean M, Kaul K, Braun MJ, Gonda MA, Vande Woude G. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci USA 84: 6379-6383, 1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6379-6383
    • Park, M.1    Dean, M.2    Kaul, K.3    Braun, M.J.4    Gonda, M.A.5    Vande Woude, G.6
  • 96
    • 12344330373 scopus 로고    scopus 로고
    • Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: Role of the renin-angiotensin system
    • Rizkalla B, Forbes JM, Cao Z, Boner G, Cooper ME. Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system. J Hypertens 23: 153–164, 2005.
    • (2005) J Hypertens , vol.23 , pp. 153-164
    • Rizkalla, B.1    Forbes, J.M.2    Cao, Z.3    Boner, G.4    Cooper, M.E.5
  • 98
    • 84856708866 scopus 로고    scopus 로고
    • Endothelial glycocalyx dysfunction in disease: Albuminuria and increased microvascular permeability
    • Salmon AH, Satchell SC. Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability. J Pathol 226: 562–574, 2012.
    • (2012) J Pathol , vol.226 , pp. 562-574
    • Salmon, A.H.1    Satchell, S.C.2
  • 99
    • 66049109286 scopus 로고    scopus 로고
    • Glomerular endothelial cell fenestrations: An integral component of the glomerular filtration barrier
    • Satchell SC, Braet F. Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier. Am J Physiol Renal Physiol 296: F947–F956, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.296 , pp. F947-F956
    • Satchell, S.C.1    Braet, F.2
  • 100
    • 41849137193 scopus 로고    scopus 로고
    • What is the mechanism of microalbuminuria in diabetes: A role for the glomerular endothelium?
    • Satchell SC, Tooke JE. What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium? Diabetologia 51: 714– 725, 2008.
    • (2008) Diabetologia , vol.51
    • Satchell, S.C.1    Tooke, J.E.2
  • 102
    • 84899729677 scopus 로고    scopus 로고
    • Putting the glomerulus back together: Per aspera ad astra (“a rough road leads to the stars”)
    • Schlondorff D. Putting the glomerulus back together: per aspera ad astra (“a rough road leads to the stars”). Kidney Int 85: 991–998, 2014.
    • (2014) Kidney Int , vol.85 , pp. 991-998
    • Schlondorff, D.1
  • 103
    • 67449083682 scopus 로고    scopus 로고
    • The mesangial cell revisited: No cell is an island
    • Schlondorff D, Banas B. The mesangial cell revisited: no cell is an island. J Am Soc Nephrol 20: 1179–1187, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1179-1187
    • Schlondorff, D.1    Banas, B.2
  • 105
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87: 4–14, 2010.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 107
    • 84862756066 scopus 로고    scopus 로고
    • Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes
    • Slater SC, Ramnath RD, Uttridge K, Saleem MA, Cahill PA, Ma-thieson PW, Welsh GI, Satchell SC. Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes. Int J Biochem Cell Biol 44: 1482–1490, 2012.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1482-1490
    • Slater, S.C.1    Ramnath, R.D.2    Uttridge, K.3    Saleem, M.A.4    Cahill, P.A.5    Ma-Thieson, P.W.6    Welsh, G.I.7    Satchell, S.C.8
  • 108
    • 0027437547 scopus 로고
    • Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
    • Sonnenberg E, Meyer D, Weidner KM, Birchmeier C. Scatter factor/ hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J Cell Biol 123: 223–235, 1993.
    • (1993) J Cell Biol , vol.123 , pp. 223-235
    • Sonnenberg, E.1    Meyer, D.2    Weidner, K.M.3    Birchmeier, C.4
  • 109
    • 34547632121 scopus 로고    scopus 로고
    • The glomerular injury of preeclampsia
    • Stillman IE, Karumanchi SA. The glomerular injury of preeclampsia. J Am Soc Nephrol 18: 2281–2284, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2281-2284
    • Stillman, I.E.1    Karumanchi, S.A.2
  • 111
    • 0037631361 scopus 로고    scopus 로고
    • Neutralization of circulating vascular endothe-lial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria
    • Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R. Neutralization of circulating vascular endothe-lial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem 278: 12605–12608, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 12605-12608
    • Sugimoto, H.1    Hamano, Y.2    Charytan, D.3    Cosgrove, D.4    Kieran, M.5    Sudhakar, A.6    Kalluri, R.7
  • 112
    • 84872843610 scopus 로고    scopus 로고
    • Glomerular endothelial cell injury and damage precedes that of podocytes in adria-mycin-induced nephropathy
    • Sun YB, Qu X, Zhang X, Caruana G, Bertram JF, Li J. Glomerular endothelial cell injury and damage precedes that of podocytes in adria-mycin-induced nephropathy. PLoS One 8: e55027, 2013.
    • (2013) Plos One , pp. 8
    • Sun, Y.B.1    Qu, X.2    Zhang, X.3    Caruana, G.4    Bertram, J.F.5    Li, J.6
  • 113
    • 33750713086 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice
    • Sung SH, Ziyadeh FN, Wang A, Pyagay PE, Kanwar YS, Chen S. Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice. J Am Soc Nephrol 17: 3093–3104, 2006.
    • (2006) Jam Soc Nephrol , vol.17 , pp. 3093-3104
    • Sung, S.H.1    Ziyadeh, F.N.2    Wang, A.3    Pyagay, P.E.4    Kanwar, Y.S.5    Chen, S.6
  • 115
    • 33644783770 scopus 로고    scopus 로고
    • Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
    • Susztak K, Raff AC, Schiffer M, Bottinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55: 225–233, 2006.
    • (2006) Diabetes , vol.55 , pp. 225-233
    • Susztak, K.1    Raff, A.C.2    Schiffer, M.3    Bottinger, E.P.4
  • 116
    • 0027631720 scopus 로고
    • Transcriptional activation of matrix genes by transforming growth factor beta 1 in mesangial cells
    • Suzuki S, Ebihara I, Tomino Y, Koide H. Transcriptional activation of matrix genes by transforming growth factor beta 1 in mesangial cells. Exp Nephrol 1: 229–237, 1993.
    • (1993) Exp Nephrol , vol.1 , pp. 229-237
    • Suzuki, S.1    Ebihara, I.2    Tomino, Y.3    Koide, H.4
  • 118
    • 58149192157 scopus 로고    scopus 로고
    • The endothelial glycocalyx: A mechano-sensor and -transducer
    • Tarbell JM, Ebong EE. The endothelial glycocalyx: a mechano-sensor and -transducer. Sci Signal 1: pt8, 2008.
    • (2008) Sci Signal , vol.1
    • Tarbell, J.M.1    Ebong, E.E.2
  • 120
    • 78149298673 scopus 로고    scopus 로고
    • Induction of podocyte VEGF164 overexpres-sion at different stages of development causes congenital nephrosis or steroid-resistant nephrotic syndrome
    • Veron D, Reidy K, Marlier A, Bertuccio C, Villegas G, Jimenez J, Kashgarian M, Tufro A. Induction of podocyte VEGF164 overexpres-sion at different stages of development causes congenital nephrosis or steroid-resistant nephrotic syndrome. Am J Pathol 177: 2225–2233, 2010.
    • (2010) Am J Pathol , vol.177 , pp. 2225-2233
    • Veron, D.1    Reidy, K.2    Marlier, A.3    Bertuccio, C.4    Villegas, G.5    Jimenez, J.6    Kashgarian, M.7    Tufro, A.8
  • 123
    • 16844383687 scopus 로고    scopus 로고
    • Diabetic nephropathy: The proteinuria hypothesis
    • Williams ME. Diabetic nephropathy: the proteinuria hypothesis. Am J Nephrol 25: 77–94, 2005.
    • (2005) Am J Nephrol , vol.25 , pp. 77-94
    • Williams, M.E.1
  • 124
    • 59949085812 scopus 로고    scopus 로고
    • Roles of angiopoietins in kidney development and disease
    • Woolf AS, Gnudi L, Long DA. Roles of angiopoietins in kidney development and disease. J Am Soc Nephrol 20: 239–244, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 239-244
    • Woolf, A.S.1    Gnudi, L.2    Long, D.A.3
  • 125
    • 33644877366 scopus 로고    scopus 로고
    • TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes
    • Wu DT, Bitzer M, Ju W, Mundel P, Bottinger EP. TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes. J Am Soc Nephrol 16: 3211–3221, 2005.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3211-3221
    • Wu, D.T.1    Bitzer, M.2    Ju, W.3    Mundel, P.4    Bottinger, E.P.5
  • 126
    • 68049102222 scopus 로고    scopus 로고
    • TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho-and myosin light chain kinase-dependent mechanism
    • Wu X, Guo R, Chen P, Wang Q, Cunningham PN. TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho-and myosin light chain kinase-dependent mechanism. Am J Physiol Renal Physiol 297: F316–F326, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.297 , pp. F316-F326
    • Wu, X.1    Guo, R.2    Chen, P.3    Wang, Q.4    Cunningham, P.N.5
  • 127
    • 84891555200 scopus 로고    scopus 로고
    • TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis
    • Xu C, Chang A, Hack BK, Eadon MT, Alper SL, Cunningham PN. TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis. Kidney Int 85: 72–81, 2014.
    • (2014) Kidney Int , vol.85 , pp. 72-81
    • Xu, C.1    Chang, A.2    Hack, B.K.3    Eadon, M.T.4    Alper, S.L.5    Cunningham, P.N.6
  • 129
    • 3042739353 scopus 로고    scopus 로고
    • Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy
    • Yamamoto Y, Maeshima Y, Kitayama H, Kitamura S, Takazawa Y, Sugiyama H, Yamasaki Y, Makino H. Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy. Diabetes 53: 1831–1840, 2004.
    • (2004) Diabetes , vol.53 , pp. 1831-1840
    • Yamamoto, Y.1    Maeshima, Y.2    Kitayama, H.3    Kitamura, S.4    Takazawa, Y.5    Sugiyama, H.6    Yamasaki, Y.7    Makino, H.8
  • 130
    • 0036138824 scopus 로고    scopus 로고
    • Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis
    • Yang J, Liu Y. Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis. J Am Soc Nephrol 13: 96–107, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 96-107
    • Yang, J.1    Liu, Y.2
  • 131
    • 36849053415 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt
    • Yano T, Liu Z, Donovan J, Thomas MK, Habener JF. Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt. Diabetes 56: 2946–2957, 2007.
    • (2007) Diabetes , vol.56 , pp. 2946-2957
    • Yano, T.1    Liu, Z.2    Donovan, J.3    Thomas, M.K.4    Habener, J.F.5
  • 132
    • 0027450159 scopus 로고
    • Transforming growth factor-beta protein and mRNA in glomeruli in normal and diseased human kidneys
    • Yoshioka K, Takemura T, Murakami K, Okada M, Hino S, Miyamoto H, Maki S. Transforming growth factor-beta protein and mRNA in glomeruli in normal and diseased human kidneys. Lab Invest 68: 154–163, 1993.
    • (1993) Lab Invest , vol.68 , pp. 154-163
    • Yoshioka, K.1    Takemura, T.2    Murakami, K.3    Okada, M.4    Hino, S.5    Miyamoto, H.6    Maki, S.7
  • 133
    • 0026233110 scopus 로고
    • Reactive oxygen metabolites cause massive, reversible proteinuria and glomerular sieving defect without apparent ultrastructural abnormality
    • Yoshioka T, Ichikawa I, Fogo A. Reactive oxygen metabolites cause massive, reversible proteinuria and glomerular sieving defect without apparent ultrastructural abnormality. J Am Soc Nephrol 2: 902–912, 1991.
    • (1991) J Am Soc Nephrol , vol.2 , pp. 902-912
    • Yoshioka, T.1    Ichikawa, I.2    Fogo, A.3
  • 135
    • 0033917346 scopus 로고    scopus 로고
    • Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism
    • Zanchi A, Moczulski DK, Hanna LS, Wantman M, Warram JH, Krolewski AS. Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism. Kidney Int 57: 405–413, 2000.
    • (2000) Kidney Int , vol.57 , pp. 405-413
    • Zanchi, A.1    Moczulski, D.K.2    Hanna, L.S.3    Wantman, M.4    Warram, J.H.5    Krolewski, A.S.6
  • 136


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