TGFβ enforces activation of eukaryotic elongation factor-2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy

FEBS Letters

Volumn 584, Issue 19, 2010, Pages 4268-4272

  Das, Falguni ^a   Ghosh Choudhury, Nandini ^a,b   Kasinath, Balakuntalam S ^a,b   Choudhury, Goutam Ghosh ^a,b  

^a University of Texas Health Science Center at San Antonio   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Diabetic nephropathy; MRNA translation; Receptor serine threonine kinase

Indexed keywords

ELONGATION FACTOR; EUKARYOTIC ELONGATION FACTOR 2; MESSENGER RNA; PROTEIN P90; PROTEIN P90 RIBOSOMAL S6 KINASE; SERINE; THREONINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL HYPERTROPHY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; HYPERTROPHY; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; RAT; RNA TRANSLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL ENLARGEMENT; ELONGATION FACTOR 2 KINASE; EUKARYOTIC INITIATION FACTOR-2; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MESANGIAL CELLS; PEPTIDES, CYCLIC; PHOSPHORYLATION; RATS; RECOMBINANT PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; TRANSFORMING GROWTH FACTOR BETA;

EUKARYOTA;

EID: 77957147501     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.09.010     Document Type: Article

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