Guttiferone A Aggregates Modulate Silent Information Regulator 1 (SIRT1) Activity

Journal of Medicinal Chemistry

Volumn 59, Issue 20, 2016, Pages 9560-9566

  Cottet, Kévin ^a   Xu, Bin ^a   Coric, Pascale ^b   Bouaziz, Serge ^b   Michel, Sylvie ^a   Vidal, Michel ^a,c   Lallemand, Marie Christine ^a   Broussy, Sylvain ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Institut Cochin   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARISTOFORIN; ENZYME INHIBITOR; GUTTIFERONE A; GUTTIFERONE G; HYPERFORIN; HYPERICUM PERFORATUM EXTRACT; JQ 101; PLANT EXTRACT; RESVERATROL; SILENT INFORMATION REGULATOR PROTEIN; SILENT INFORMATION REGULATOR PROTEIN 1; SILENT INFORMATION REGULATOR PROTEIN 2; SURAMIN; UNCLASSIFIED DRUG; BENZOPHENONE DERIVATIVE; BIOLOGICAL PRODUCT; SIRT1 PROTEIN, HUMAN; SIRTUIN 1;

ANIMAL TISSUE; ARTICLE; BOVINE; CLUSIACEAE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME INHIBITION ASSAY; HUMAN; HYPERICUM PERFORATUM; IC50; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION; SYMPHONIA GLOBULIFERA; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR MODEL; PHOTON CORRELATION SPECTROSCOPY;

BENZOPHENONES; BIOLOGICAL PRODUCTS; CLUSIACEAE; DOSE-RESPONSE RELATIONSHIP, DRUG; DYNAMIC LIGHT SCATTERING; ENZYME INHIBITORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SIRTUIN 1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84993999919     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.6b01182     Document Type: Article

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