Isolation of Guttiferones from Renewable Parts of Symphonia globulifera by Centrifugal Partition Chromatography

Planta Medica

Volumn 81, Issue 17, 2015, Pages 1604-1608

  Cottet, Kevin ^a   Fromentin, Yann ^a   Kritsanida, Marina ^a   Grougnet, Raphaël ^a   Odonne, Guillaume ^b   Duplais, Christophe ^c   Michel, Sylvie ^a   Lallemand, Marie Christine ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b Centre National de la Recherche Scientifique   (France)

^c INSTITUT PASTEUR DE LA GUYANE   (French Guiana)

Author keywords

centrifugal partition chromatography; Clusiaceae; countercurrent chromatography guttiferones; PPAPs; Symphonia globulifera

Indexed keywords

ACETIC ACID ETHYL ESTER; CYCLOHEXANE; GUTTIFERONE A; GUTTIFERONE B; GUTTIFERONE C; GUTTIFERONE D; LATEX; METHANOL; PHLOROGLUCINOL; PLANT EXTRACT; SYMPHONIA GLOBULIFERA EXTRACT; UNCLASSIFIED DRUG; WATER; BENZOPHENONE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PURITY; DRUG STRUCTURE; FLOWER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; METHODOLOGY; PARTITION CHROMATOGRAPHY; PHYSICAL CHEMISTRY; PLANT SEED; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION; SYMPHONIA GLOBULIFERA; THIN LAYER CHROMATOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; CLUSIACEAE; DENSITY GRADIENT CENTRIFUGATION; ISOLATION AND PURIFICATION; PROCEDURES;

BENZOPHENONES; CENTRIFUGATION, DENSITY GRADIENT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLUSIACEAE; MOLECULAR STRUCTURE;

EID: 84949814286     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0035-1557773     Document Type: Article

References (15)

1. Marti G., Eparvier V., Moretti C., Prado S., Grellier P., Hue N., Thoison O., Delpech B., Guéritte F., Litaudon M. Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae). Phytochemistry: 2010; 71 964 974
2. Verotta L. Are acylphloroglucinols lead structures for the treatment of degenerative diseases? Phytochem Rev: 2002; 1 389 407
3. Ciochina R., Grossman R. B. Polycyclic polyprenylated acylphloroglucinols. Chem Rev: 2006; 106 3963 3986
4. Singh I. P., Sidana J., Bharate S. B., Foley W. Phloroglucinol compounds of natural origin: synthetic aspects. Nat Prod Rep: 2010; 27 393 416
5. Njardarson J. T. Synthetic efforts toward [3. 3.1] bridged bicyclic phloroglucinol natural products. Tetrahedron: 2011; 67 7631 7666
6. Richard J. A., Pouwer R. H., Chen D. YK. The chemistry of the polycyclic polyprenylated acylphloroglucinols (PPAPs). Angew Chem Int Ed: 2012; 51 4536 4561
7. Croft S. L., Sundar S., Fairlamb A. H. Drug resistance in leishmaniasis. Clin Microbiol Rev: 2006; 19 111 126
8. Polonio T., Efferth T. Leishmaniasis: drug resistance and natural products. Int J Mol Med: 2008; 22 277 286
9. Lenta B., Vonthron-Sénécheau C., Weniger B., Devkota K., Ngoupayo J., Kaiser M., Naz Q., Choudhary M., Tsamo E., Sewald N. Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera. Molecules: 2007; 12 1548 1557
10. Fromentin Y., Gaboriaud-Kolar N., Ndjakou Lenta B., Wansi J. D., Buisson D., Mouray E., Grellier P., Loiseau P. M., Lallemand M. C., Michel S. Synthesis of novel guttiferone A derivatives: in-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani. Eur J Med Chem: 2013; 65 284 294
11. Gustafson K. R., Blunt J. W., Munro M. HG, Fuller R. W., Mckee T. C., Cardellina J. H., Mcmahon J. B., Cragg G. M., Boyd M. R. The guttiferone, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea. Tetrahedron: 1992; 48 10093 10102
12. Ngouela S., Lenta B. N., Noungoue D. T., Diderot T., Ngoupavo J., Boyom F., Fekam F., Tsamo E., Gut J., Rosenthal P. J., Connolly J. D. An antiproliferative xanthone of Symphonia pauciflora from the Madagascar rainforest. Phytochemistry: 2006; 67 302 306
13. Kaur R., Chattopadhyay S. K., Tandon S., Sharma S. Large scale extraction of the fruits of Garcinia indica for the isolation of new and known polyisoprenylated benzophenone derivatives. Ind Crops Prod: 2012; 37 420 426
14. Ollivier A., Grougnet R., Cachet X., Meriane D., Ardisson J., Boutefnouchet S., Deguin B. Large scale purification of the SERCA inhibitor thapsigargin from Thapsia garganica L. roots using centrifugal partition chromatography. J Chromatogr B: 2013; 926 16 20
15. Fromentin Y., Grellier P., Wansi J. D., Lallemand M. C., Buisson D. Yeast-Mediated xanthone synthesis through oxidative intramolecular cyclization. Org Lett: 2012; 14 5054 5057