Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production

Oncotarget

Volumn 7, Issue 40, 2016, Pages 65454-65470

  Ullmann, Pit ^a   Qureshi Baig, Komal ^a   Rodriguez, Fabien ^a   Ginolhac, Aurélien ^a   Nonnenmacher, Yannic ^a   Ternes, Dominik ^a   Weiler, Jil ^a   Gäbler, Karoline ^a   Bahlawane, Christelle ^a   Hiller, Karsten ^a   Haan, Serge ^a   Letellier, Elisabeth ^a  

^a UNIVERSITY OF LUXEMBOURG   (Luxembourg)

Author keywords

Colorectal cancer; Hypoxia; MiR 210; Self renewal capacity; Tumor initiating cell

Indexed keywords

CASPASE 3; GLUCOSE; GLUTAMINE; LACTIC ACID; MICRORNA; MICRORNA 210; IRON SULFUR PROTEIN; ISCU PROTEIN, HUMAN; MIRN210 MICRORNA, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL; CANCER INCIDENCE; CANCER PATIENT; CANCER SURVIVAL; CARCINOGENICITY; CELL POPULATION; CELL SELF-RENEWAL; CITRIC ACID CYCLE; COLON CANCER; COLON TUMOR; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOLYSIS; GENE TARGETING; GLUCOSE BLOOD LEVEL; GLYCOLYSIS; HUMAN; HUMAN TISSUE; HYPOXIA; IN VIVO STUDY; PHENOTYPE; UPREGULATION; WESTERN BLOTTING; AGED; CANCER STAGING; CANCER STEM CELL; CARCINOGENESIS; COLON; COLORECTAL TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CARCINOGENESIS; CELL SELF RENEWAL; COLON; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA; IRON-SULFUR PROTEINS; LACTIC ACID; MALE; MICRORNAS; MIDDLE AGED; NEOPLASM STAGING; NEOPLASTIC STEM CELLS; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 84993143355     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11772     Document Type: Article

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