Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection

Nature Communications

Volumn 5, Issue , 2014, Pages

  Kiga, Kotaro ^a,b   Mimuro, Hitomi ^a   Suzuki, Masato ^a   Shinozaki Ushiku, Aya ^c   Kobayashi, Taira ^a   Sanada, Takahito ^a   Kim, Minsoo ^a   Ogawa, Michinaga ^a   Iwasaki, Yuka W ^b   Kayo, Hiroyuki ^b   Fukuda Yuzawa, Yoko ^b   Yashiro, Masakazu ^d   Fukayama, Masashi ^c   Fukao, Taro ^b   Sasakawa, Chihiro ^a,e,f  

^a UNIVERSITY OF TOKYO   (Japan)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c UNIVERSITY OF TOKYO   (Japan)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e NIPPON INSTITUTE FOR BIOLOGICAL SCIENCE   (Japan)

^f CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA METHYLTRANSFERASE; MICRORNA; MICRORNA 132; MICRORNA 210; MICRORNA 375; MICRORNA 99A; UNCLASSIFIED DRUG; 16S RRNA (ADENINE(1518)-N(6)-ADENINE(1519)-N(6))-DIMETHYLTRANSFERASE; METHYLTRANSFERASE; MIRN210 MICRORNA, HUMAN; PROTEIN BINDING; SMALL INTERFERING RNA; STATHMIN; STMN1 PROTEIN, HUMAN;

BACTERIAL DISEASE; CANCER; DIGESTIVE SYSTEM DISORDER; INHIBITION; METHYLATION; MUCUS; RNA;

ANIMAL TISSUE; ARTICLE; BACTERIUM COLONY; BACTERIUM CULTURE; CANCER PATIENT; CANCER RISK; CELL PROLIFERATION; CLINICAL ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; CPG ISLAND; DIMT1 GENE; DNA METHYLATION; DNA SEQUENCE; DOWN REGULATION; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HELICOBACTER INFECTION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; IN VIVO STUDY; MALE; MERIONES UNGUICULATUS; MICROARRAY ANALYSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN BLOOD LEVEL; RNA DEGRADATION; STMN1 GENE; STOMACH BIOPSY; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH DISEASE; STOMACH EPITHELIUM; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CYCLE; CHRONIC DISEASE; COMPLICATION; DNA MICROARRAY; EPITHELIUM CELL; GASTRIC MUCOSA; GENETIC EPIGENESIS; GENETICS; GERBIL; HELICOBACTER PYLORI; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE; PROMOTER REGION; SIGNAL TRANSDUCTION; STOMACH TUMOR;

HELICOBACTER PYLORI;

ANIMALS; CELL CYCLE; CELL PROLIFERATION; CHRONIC DISEASE; DNA METHYLATION; EPIGENESIS, GENETIC; EPITHELIAL CELLS; GASTRIC MUCOSA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GERBILLINAE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; METHYLTRANSFERASES; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRIMARY CELL CULTURE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STATHMIN; STOMACH NEOPLASMS;

EID: 84910145153     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5497     Document Type: Article

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