-
1
-
-
48249125791
-
Malignant gliomas in adults
-
Wen P., Kesari S. Malignant gliomas in adults. N. Engl. J. Med. 2008, 359:492-507.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 492-507
-
-
Wen, P.1
Kesari, S.2
-
2
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh S.K., Clarke I.D., Terasaki M., et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003, 63:5821-5828.
-
(2003)
Cancer Res.
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
3
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K., Hawkins C., Clarke I.D., et al. Identification of human brain tumour initiating cells. Nature 2004, 432:396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
4
-
-
34249332411
-
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
-
Beier D., Hau P., Proescholdt M., et al. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res. 2007, 67:4010-4015.
-
(2007)
Cancer Res.
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
-
5
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen J.M., Jordan C.T. The increasing complexity of the cancer stem cell paradigm. Science 2009, 324:1670-1673.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
6
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
-
7
-
-
84873708775
-
Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas
-
Ciceroni C., Bonelli M., Mastrantoni E., et al. Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas. Cell Death Differ. 2013, 20:396-407.
-
(2013)
Cell Death Differ.
, vol.20
, pp. 396-407
-
-
Ciceroni, C.1
Bonelli, M.2
Mastrantoni, E.3
-
8
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C., Poppleton H., Kocak M., et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007, 11:69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
-
9
-
-
78650153633
-
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
-
Ricci-Vitiani L., Pallini R., Biffoni M., et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010, 468:824-828.
-
(2010)
Nature
, vol.468
, pp. 824-828
-
-
Ricci-Vitiani, L.1
Pallini, R.2
Biffoni, M.3
-
10
-
-
77952330272
-
Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma
-
Pistollato F., Abbadi S., Rampazzo E., et al. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells 2010, 28:851-862.
-
(2010)
Stem Cells
, vol.28
, pp. 851-862
-
-
Pistollato, F.1
Abbadi, S.2
Rampazzo, E.3
-
11
-
-
70350225829
-
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
-
Heddleston J.M., Li Z., McLendon R.E., Hjelmeland A.B., Rich J.N. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009, 8:3274-3284.
-
(2009)
Cell Cycle
, vol.8
, pp. 3274-3284
-
-
Heddleston, J.M.1
Li, Z.2
McLendon, R.E.3
Hjelmeland, A.B.4
Rich, J.N.5
-
12
-
-
65549150903
-
Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro
-
McCord A.M., Jamal M., Shankavarum U.T., Lang F.F., Camphausen K., Tofilon P.J. Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro. Mol. Cancer Res. 2009, 7:489-497.
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 489-497
-
-
McCord, A.M.1
Jamal, M.2
Shankavarum, U.T.3
Lang, F.F.4
Camphausen, K.5
Tofilon, P.J.6
-
13
-
-
77956503727
-
Hypoxia increases the expression of stem cell markers and promotes clonogenicity in glioblastoma neurospheres
-
Bar E.E., Lin A., Mahairaki V., Matsui W., Eberhart C.G. Hypoxia increases the expression of stem cell markers and promotes clonogenicity in glioblastoma neurospheres. Am. J. Pathol. 2010, 177:1491-1502.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 1491-1502
-
-
Bar, E.E.1
Lin, A.2
Mahairaki, V.3
Matsui, W.4
Eberhart, C.G.5
-
14
-
-
84655161946
-
HIF1α and HIF2α: sibling rivalry in hypoxic tumor growth and progression
-
Keith B., Johnson R.S., Simon M.C. HIF1α and HIF2α: sibling rivalry in hypoxic tumor growth and progression. Nat. Rev. Cancer 2011, 12:9-22.
-
(2011)
Nat. Rev. Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
15
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z., Bao S., Wu Q., et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009, 15:501-513.
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
Bao, S.2
Wu, Q.3
-
16
-
-
84904285776
-
MicroRNAs-the next generation therapeutic targets in human diseases
-
Srinivasan S., Selvan S.T., Archunan G., Gulyas B., Padmanabhan P. MicroRNAs-the next generation therapeutic targets in human diseases. Theranostics 2013, 3:930-942.
-
(2013)
Theranostics
, vol.3
, pp. 930-942
-
-
Srinivasan, S.1
Selvan, S.T.2
Archunan, G.3
Gulyas, B.4
Padmanabhan, P.5
-
17
-
-
70649084123
-
Emerging roles of microRNAs in the molecular responses to hypoxia
-
Crosby M.E., Devlin C.M., Glazer P.M., Calin G.A., Ivan M. Emerging roles of microRNAs in the molecular responses to hypoxia. Curr. Pharm. Des. 2009, 15:3861-3866.
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 3861-3866
-
-
Crosby, M.E.1
Devlin, C.M.2
Glazer, P.M.3
Calin, G.A.4
Ivan, M.5
-
18
-
-
70349168446
-
Hypoxia-inducible miR-210 regulates normoxic gene expression involved in tumor initiation
-
Huang X., Ding L., Bennewith K.L., et al. Hypoxia-inducible miR-210 regulates normoxic gene expression involved in tumor initiation. Mol. Cell 2009, 35:856-867.
-
(2009)
Mol. Cell
, vol.35
, pp. 856-867
-
-
Huang, X.1
Ding, L.2
Bennewith, K.L.3
-
19
-
-
36849077497
-
Regulation of microRNA expression: the Hypoxic Component
-
Kulshreshtha R., Ferracin M., Negrini M., Calin G.A., Davuluri R.V., Ivan M. Regulation of microRNA expression: the Hypoxic Component. Cell Cycle 2007, 6:1426-1431.
-
(2007)
Cell Cycle
, vol.6
, pp. 1426-1431
-
-
Kulshreshtha, R.1
Ferracin, M.2
Negrini, M.3
Calin, G.A.4
Davuluri, R.V.5
Ivan, M.6
-
20
-
-
69749107748
-
MicroRNA miR-210 modulates cellular response to hypoxia through the Myc antagonist MNT
-
Zhang Z., Sun H., Dai H.Y., et al. MicroRNA miR-210 modulates cellular response to hypoxia through the Myc antagonist MNT. Cell Cycle 2009, 8:2756-2768.
-
(2009)
Cell Cycle
, vol.8
, pp. 2756-2768
-
-
Zhang, Z.1
Sun, H.2
Dai, H.Y.3
-
21
-
-
70349478990
-
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
-
Chan S.Y., Zhang Y.Y., Hemann C., Mahoney C.E., Zweier J.L., Loscalzo J. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab. 2009, 10:273-284.
-
(2009)
Cell Metab.
, vol.10
, pp. 273-284
-
-
Chan, S.Y.1
Zhang, Y.Y.2
Hemann, C.3
Mahoney, C.E.4
Zweier, J.L.5
Loscalzo, J.6
-
22
-
-
47049119934
-
MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3
-
Fasanaro P., D'Alessandra Y., Di Stefano V., Melchionna R., Romani S., Pompilio G., Capogrossi M.C., Martelli F. MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J. Biol. Chem. 2008, 283:15878-15883.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15878-15883
-
-
Fasanaro, P.1
D'Alessandra, Y.2
Di Stefano, V.3
Melchionna, R.4
Romani, S.5
Pompilio, G.6
Capogrossi, M.C.7
Martelli, F.8
-
23
-
-
70450240736
-
Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2
-
Kim H.W., Haider H.K., Jiang S., Ashraf M. Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2. J. Biol. Chem. 2009, 284:33161-33168.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 33161-33168
-
-
Kim, H.W.1
Haider, H.K.2
Jiang, S.3
Ashraf, M.4
-
24
-
-
84876947528
-
Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2
-
Kim J.H., Park S.G., Song S.Y., Kim J.K., Sung J.H. Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2. Cell Death Dis. 2013, 4:e588.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Kim, J.H.1
Park, S.G.2
Song, S.Y.3
Kim, J.K.4
Sung, J.H.5
-
25
-
-
84871292051
-
Synthetic miRNA-mowers targeting miR-183-96-182 cluster or miR-210 inhibit growth and migration and induce apoptosis in bladder cancer cells
-
Liu Y., Han Y., Zhang H., et al. Synthetic miRNA-mowers targeting miR-183-96-182 cluster or miR-210 inhibit growth and migration and induce apoptosis in bladder cancer cells. PLoS One 2012, 7:e52280.
-
(2012)
PLoS One
, vol.7
-
-
Liu, Y.1
Han, Y.2
Zhang, H.3
-
26
-
-
84871255599
-
MiR-210: a therapeutic target in cancer
-
Hong L., Han Y., Zhang H., Zhao Q., Qiao Y. miR-210: a therapeutic target in cancer. Expert Opin. Ther. Targets 2013, 17:21-28.
-
(2013)
Expert Opin. Ther. Targets
, vol.17
, pp. 21-28
-
-
Hong, L.1
Han, Y.2
Zhang, H.3
Zhao, Q.4
Qiao, Y.5
-
27
-
-
84862781979
-
Downregulation of miR-210 expression inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro
-
Yang W., Sun T., Cao J., Liu F.J., Tian Y., Zhu W. Downregulation of miR-210 expression inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro. Exp. Cell Res. 2012, 318:944-954.
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 944-954
-
-
Yang, W.1
Sun, T.2
Cao, J.3
Liu, F.J.4
Tian, Y.5
Zhu, W.6
-
28
-
-
84875911885
-
MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines
-
Grosso S., Doyen J., Parks S.K., et al. MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines. Cell Death Dis. 2013, 4:e544.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Grosso, S.1
Doyen, J.2
Parks, S.K.3
-
29
-
-
0031027008
-
Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites
-
Hurlin P.J., Queva C., Eisenman R.N. Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites. Genes Dev. 1997, 11:44-58.
-
(1997)
Genes Dev.
, vol.11
, pp. 44-58
-
-
Hurlin, P.J.1
Queva, C.2
Eisenman, R.N.3
-
30
-
-
33748136848
-
The MAX-interacting transcription factor network
-
Hurlin P.J., Huang J. The MAX-interacting transcription factor network. Semin. Cancer Biol. 2006, 16:265-274.
-
(2006)
Semin. Cancer Biol.
, vol.16
, pp. 265-274
-
-
Hurlin, P.J.1
Huang, J.2
-
31
-
-
79959425207
-
A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1α stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like
-
Timothy J.K., Amanda L.S., Clary B.C., Pere P. A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1α stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like. Mol. Cell Biol. 2011, 31:2696-2706.
-
(2011)
Mol. Cell Biol.
, vol.31
, pp. 2696-2706
-
-
Timothy, J.K.1
Amanda, L.S.2
Clary, B.C.3
Pere, P.4
-
32
-
-
56849131763
-
C-Myc is required for maintenance of glioma cancer stem cells
-
Wang J., Wang H., Li Z., et al. c-Myc is required for maintenance of glioma cancer stem cells. PLoS ONE 2008, 3:e3769.
-
(2008)
PLoS ONE
, vol.3
-
-
Wang, J.1
Wang, H.2
Li, Z.3
-
34
-
-
77952111459
-
MiR-210-micromanager of the hypoxia pathway
-
Huang X., Le Q.T., Giaccia A.J. MiR-210-micromanager of the hypoxia pathway. Trends Mol. Med. 2010, 16:230-237.
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 230-237
-
-
Huang, X.1
Le, Q.T.2
Giaccia, A.J.3
-
35
-
-
84859143381
-
MiR-210: the master hypoxamir
-
Chan Y.C., Banerjee J., Choi S.Y., Sen C.K. miR-210: the master hypoxamir. Microcirculation 2012, 19:215-223.
-
(2012)
Microcirculation
, vol.19
, pp. 215-223
-
-
Chan, Y.C.1
Banerjee, J.2
Choi, S.Y.3
Sen, C.K.4
-
36
-
-
80053259947
-
MicroRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects
-
Mutharasan R.K., Nagpal V., Ichikawa Y., Ardehali H. microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects. Am. J. Physiol.: Heart Circ. Physiol. 2011, 301:H1519-H1530.
-
(2011)
Am. J. Physiol.: Heart Circ. Physiol.
, vol.301
-
-
Mutharasan, R.K.1
Nagpal, V.2
Ichikawa, Y.3
Ardehali, H.4
-
37
-
-
34047156190
-
HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity
-
Gordan J.D., Bertovrt J.A., Hu C.J., Diehl J.A., Simon M.C. HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity. Cancer Cell 2007, 11:335-347.
-
(2007)
Cancer Cell
, vol.11
, pp. 335-347
-
-
Gordan, J.D.1
Bertovrt, J.A.2
Hu, C.J.3
Diehl, J.A.4
Simon, M.C.5
-
38
-
-
0842282553
-
Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation
-
Nilsson J.A., Maclean K.H., Keller U.B., Pendeville H., Baudino T.A., Cleveland J.L. Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation. Mol. Cell Biol. 2004, 24:1560-1569.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 1560-1569
-
-
Nilsson, J.A.1
Maclean, K.H.2
Keller, U.B.3
Pendeville, H.4
Baudino, T.A.5
Cleveland, J.L.6
-
39
-
-
14744305803
-
More than just proliferation: myc function in stem cells
-
Murphy M.J., Wilson A., Trumpp A. More than just proliferation: myc function in stem cells. Trends Cell Biol. 2005, 15:128-137.
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 128-137
-
-
Murphy, M.J.1
Wilson, A.2
Trumpp, A.3
-
40
-
-
41449118521
-
Module map of stem cell genes guides creation of epithelial cancer stem cells
-
Wong D.J., Liu H., Ridky T.W., Cassarino D., Segal E., Chang H.Y. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2008, 2:333-344.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 333-344
-
-
Wong, D.J.1
Liu, H.2
Ridky, T.W.3
Cassarino, D.4
Segal, E.5
Chang, H.Y.6
-
41
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
42
-
-
82455162648
-
Hypoxia-inducible microRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma
-
Ying Q., Liang L., Guo W., Zha R., Tian Q., Huang S. Hypoxia-inducible microRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma. Hepatology 2011, 54:2064-2075.
-
(2011)
Hepatology
, vol.54
, pp. 2064-2075
-
-
Ying, Q.1
Liang, L.2
Guo, W.3
Zha, R.4
Tian, Q.5
Huang, S.6
-
43
-
-
77955170881
-
Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression
-
Chen Z., Li Y., Zhang H., Huang P., Luthra R. Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene 2010, 29:4362-4368.
-
(2010)
Oncogene
, vol.29
, pp. 4362-4368
-
-
Chen, Z.1
Li, Y.2
Zhang, H.3
Huang, P.4
Luthra, R.5
-
44
-
-
79951678403
-
MiR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity
-
Puissegur M.P., Mazure N.M., Bertero T., et al. miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity. Cell Death Differ. 2011, 18:465-478.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 465-478
-
-
Puissegur, M.P.1
Mazure, N.M.2
Bertero, T.3
-
45
-
-
77956402239
-
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
-
Favaro E., Ramachandran A., McCormick R., et al. MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One 2010, 5:e10345.
-
(2010)
PLoS One
, vol.5
-
-
Favaro, E.1
Ramachandran, A.2
McCormick, R.3
-
46
-
-
0033912046
-
Free radical scavenging and antioxidant effects of lactate ion: an in vitro study
-
Groussard C., Morel I., Chevanne M., Monnier M., Cillard J., Delamarche A. Free radical scavenging and antioxidant effects of lactate ion: an in vitro study. J. Appl. Physiol. 2000, 89:169-175.
-
(2000)
J. Appl. Physiol.
, vol.89
, pp. 169-175
-
-
Groussard, C.1
Morel, I.2
Chevanne, M.3
Monnier, M.4
Cillard, J.5
Delamarche, A.6
-
47
-
-
74549186565
-
Glycolytic metabolism and tumour response to fractionated irradiation
-
Sattler U.G., Meyer S.S., Quennet V., et al. Glycolytic metabolism and tumour response to fractionated irradiation. Radiother. Oncol. 2010, 94:102-109.
-
(2010)
Radiother. Oncol.
, vol.94
, pp. 102-109
-
-
Sattler, U.G.1
Meyer, S.S.2
Quennet, V.3
-
49
-
-
59149091637
-
MicroRNA regulation of DNA repair gene expression in hypoxic stress
-
Crosby M.E., Kulshreshtha R., Ivan M., Glazer P.M. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 2009, 69:1221-1229.
-
(2009)
Cancer Res.
, vol.69
, pp. 1221-1229
-
-
Crosby, M.E.1
Kulshreshtha, R.2
Ivan, M.3
Glazer, P.M.4
|