-
1
-
-
84908321680
-
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex
-
25275521
-
McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. PLoS genetics 2014; 10:e1004626; PMID:25275521; http://dx.doi.org/10.1371/journal.pgen.1004626
-
(2014)
PLoS genetics
, vol.10
, pp. e1004626
-
-
McKnight, N.C.1
Zhong, Y.2
Wold, M.S.3
Gong, S.4
Phillips, G.R.5
Dou, Z.6
Zhao, Y.7
Heintz, N.8
Zong, W.X.9
Yue, Z.10
-
2
-
-
79953652969
-
The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans
-
21183797
-
Ruck A, Attonito J, Garces KT, Nunez L, Palmisano NJ, Rubel Z, Bai Z, Nguyen KC, Sun L, Grant BD, et al. The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans. Autophagy 2011; 7:386-400; PMID:21183797; http://dx.doi.org/10.4161/auto.7.4.14391
-
(2011)
Autophagy
, vol.7
, pp. 386-400
-
-
Ruck, A.1
Attonito, J.2
Garces, K.T.3
Nunez, L.4
Palmisano, N.J.5
Rubel, Z.6
Bai, Z.7
Nguyen, K.C.8
Sun, L.9
Grant, B.D.10
-
3
-
-
39049194057
-
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
-
16874027
-
Furuya N, Yu J, Byfield M, Pattingre S, Levine B. The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 2005; 1:46-52; PMID:16874027; http://dx.doi.org/10.4161/auto.1.1.1542
-
(2005)
Autophagy
, vol.1
, pp. 46-52
-
-
Furuya, N.1
Yu, J.2
Byfield, M.3
Pattingre, S.4
Levine, B.5
-
4
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
10604474
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999; 402:672-6; PMID:10604474; http://dx.doi.org/10.1038/45257
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
5
-
-
59249089394
-
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
-
18843052
-
Itakura E, Kishi C, Inoue K, Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 2008; 19:5360-72; PMID:18843052; http://dx.doi.org/10.1091/mbc.E08-01-0080
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5360-5372
-
-
Itakura, E.1
Kishi, C.2
Inoue, K.3
Mizushima, N.4
-
6
-
-
84862023791
-
Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
-
22314358
-
Li X, He L, Che KH, Funderburk SF, Pan L, Pan N, Zhang M, Yue Z, Zhao Y. Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG. Nat Commun 2012; 3:662; PMID:22314358; http://dx.doi.org/10.1038/ncomms1648
-
(2012)
Nat Commun
, vol.3
, pp. 662
-
-
Li, X.1
He, L.2
Che, K.H.3
Funderburk, S.F.4
Pan, L.5
Pan, N.6
Zhang, M.7
Yue, Z.8
Zhao, Y.9
-
7
-
-
77955895424
-
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
-
20713597
-
Matsunaga K, Morita E, Saitoh T, Akira S, Ktistakis NT, Izumi T, Noda T, Yoshimori T. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol 2010; 190:511-21; PMID:20713597; http://dx.doi.org/10.1083/jcb.200911141
-
(2010)
J Cell Biol
, vol.190
, pp. 511-521
-
-
Matsunaga, K.1
Morita, E.2
Saitoh, T.3
Akira, S.4
Ktistakis, N.T.5
Izumi, T.6
Noda, T.7
Yoshimori, T.8
-
8
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
-
Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T, et al. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Natre Cell Biol 2009; 11:385-96; http://dx.doi.org/10.1038/ncb1846
-
(2009)
Natre Cell Biol
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
Saitoh, T.2
Tabata, K.3
Omori, H.4
Satoh, T.5
Kurotori, N.6
Maejima, I.7
Shirahama-Noda, K.8
Ichimura, T.9
Isobe, T.10
-
9
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
19270693
-
Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol 2009; 11:468-76; PMID:19270693; http://dx.doi.org/10.1038/ncb1854
-
(2009)
Nat Cell Biol
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
Heintz, N.7
Yue, Z.8
-
10
-
-
58049192897
-
Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
-
Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q. Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Nail Acad Sci U S A 2008; 105:19211-6; http://dx.doi.org/10.1073/pnas.0810452105
-
(2008)
Proc Nail Acad Sci U S A
, vol.105
, pp. 19211-19216
-
-
Sun, Q.1
Fan, W.2
Chen, K.3
Ding, X.4
Chen, S.5
Zhong, Q.6
-
11
-
-
78049271501
-
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
-
20643123
-
Thoresen SB, Pedersen NM, Liestol K, Stenmark H. A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic. Exp Cell Res 2010; 316:3368-78; PMID:20643123; http://dx.doi.org/10.1016/j.yexcr.2010.07.008
-
(2010)
Exp Cell Res
, vol.316
, pp. 3368-3378
-
-
Thoresen, S.B.1
Pedersen, N.M.2
Liestol, K.3
Stenmark, H.4
-
12
-
-
35948983328
-
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
-
17984323
-
Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerod L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A. Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J Cell Biol 2007; 179:485-500; PMID:17984323; http://dx.doi.org/10.1083/jcb.200702115
-
(2007)
J Cell Biol
, vol.179
, pp. 485-500
-
-
Filimonenko, M.1
Stuffers, S.2
Raiborg, C.3
Yamamoto, A.4
Malerod, L.5
Fisher, E.M.6
Isaacs, A.7
Brech, A.8
Stenmark, H.9
Simonsen, A.10
-
13
-
-
84884262668
-
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
-
24034250
-
Wei Y, Zou Z, Becker N, Anderson M, Sumpter R, Xiao G, Kinch L, Koduru P, Christudass CS, Veltri RW, et al. EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance. Cell 2013; 154:1269-84; PMID:24034250; http://dx.doi.org/10.1016/j.cell.2013.08.015
-
(2013)
Cell
, vol.154
, pp. 1269-1284
-
-
Wei, Y.1
Zou, Z.2
Becker, N.3
Anderson, M.4
Sumpter, R.5
Xiao, G.6
Kinch, L.7
Koduru, P.8
Christudass, C.S.9
Veltri, R.W.10
-
14
-
-
84920945138
-
A kinase-independent role for EGF receptor in autophagy initiation
-
25594178
-
Tan X, Thapa N, Sun Y, Anderson RA. A kinase-independent role for EGF receptor in autophagy initiation. Cell 2015; 160:145-60; PMID:25594178; http://dx.doi.org/10.1016/j.cell.2014.12.006
-
(2015)
Cell
, vol.160
, pp. 145-160
-
-
Tan, X.1
Thapa, N.2
Sun, Y.3
Anderson, R.A.4
-
15
-
-
67549135655
-
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
-
Vicencio JM, Ortiz C, Criollo A, Jones AW, Kepp O, Galluzzi L, Joza N, Vitale I, Morselli E, Tailler M, et al. The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Different 2009; 16:1006-17; http://dx.doi.org/10.1038/cdd.2009.34
-
(2009)
Cell Death Different
, vol.16
, pp. 1006-1017
-
-
Vicencio, J.M.1
Ortiz, C.2
Criollo, A.3
Jones, A.W.4
Kepp, O.5
Galluzzi, L.6
Joza, N.7
Vitale, I.8
Morselli, E.9
Tailler, M.10
-
16
-
-
84873675881
-
A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy
-
23182941
-
Li Y, Zhao Y, Hu J, Xiao J, Qu L, Wang Z, Ma D, Chen Y. A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy. Autophagy 2013; 9:150-63; PMID:23182941; http://dx.doi.org/10.4161/auto.22742
-
(2013)
Autophagy
, vol.9
, pp. 150-163
-
-
Li, Y.1
Zhao, Y.2
Hu, J.3
Xiao, J.4
Qu, L.5
Wang, Z.6
Ma, D.7
Chen, Y.8
-
17
-
-
84872799206
-
The VMP1-Beclin 1 interaction regulates autophagy induction
-
Molejon MI, Ropolo A, Re AL, Boggio V, Vaccaro MI. The VMP1-Beclin 1 interaction regulates autophagy induction. Scient Rep 2013; 3:1055
-
(2013)
Scient Rep
, vol.3
, pp. 1055
-
-
Molejon, M.I.1
Ropolo, A.2
Re, A.L.3
Boggio, V.4
Vaccaro, M.I.5
-
18
-
-
84899977406
-
Connexins modulate autophagosome biogenesis
-
24705551
-
Bejarano E, Yuste A, Patel B, Stout RF, Jr., Spray DC, Cuervo AM. Connexins modulate autophagosome biogenesis. Nat Cell Biol 2014; 16:401-14; PMID:24705551; http://dx.doi.org/10.1038/ncb2934
-
(2014)
Nat Cell Biol
, vol.16
, pp. 401-414
-
-
Bejarano, E.1
Yuste, A.2
Patel, B.3
Stout, R.F.4
Spray, D.C.5
Cuervo, A.M.6
-
19
-
-
84880061812
-
Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation
-
23703612
-
Han J, Hou W, Lu C, Goldstein LA, Stolz DB, Watkins SC, Rabinowich H. Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation. J Biol Chem 2013; 288:20315-25; PMID:23703612; http://dx.doi.org/10.1074/jbc.M113.461350
-
(2013)
J Biol Chem
, vol.288
, pp. 20315-20325
-
-
Han, J.1
Hou, W.2
Lu, C.3
Goldstein, L.A.4
Stolz, D.B.5
Watkins, S.C.6
Rabinowich, H.7
-
20
-
-
84878956537
-
Physiological functions of APP family proteins
-
Muller UC, Zheng H. Physiological functions of APP family proteins. Cold Spring Harbor Perspect Med 2012; 2:a006288; http://dx.doi.org/10.1101/cshperspect.a006288
-
(2012)
Cold Spring Harbor Perspect Med
, vol.2
, pp. a006288
-
-
Muller, U.C.1
Zheng, H.2
-
21
-
-
84896360551
-
Lysosomal sorting of amyloid-beta by the SORLA receptor is impaired by a familial Alzheimer's disease mutation
-
24523320
-
Caglayan S, Takagi-Niidome S, Liao F, Carlo AS, Schmidt V, Burgert T, Kitago Y, Füchtbauer EM, Füchtbauer A, Holtzman DM, et al. Lysosomal sorting of amyloid-beta by the SORLA receptor is impaired by a familial Alzheimer's disease mutation. Scie Translat Med 2014; 6:223ra20; PMID:24523320
-
(2014)
Scie Translat Med
, vol.6
, pp. 223ra20
-
-
Caglayan, S.1
Takagi-Niidome, S.2
Liao, F.3
Carlo, A.S.4
Schmidt, V.5
Burgert, T.6
Kitago, Y.7
Füchtbauer, E.M.8
Füchtbauer, A.9
Holtzman, D.M.10
-
22
-
-
26444607532
-
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
-
16174740
-
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X, et al. Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proc Natl Acad Sci U S A 2005; 102:13461-6; PMID:16174740; http://dx.doi.org/10.1073/pnas.0503689102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13461-13466
-
-
Andersen, O.M.1
Reiche, J.2
Schmidt, V.3
Gotthardt, M.4
Spoelgen, R.5
Behlke, J.6
von Arnim, C.A.7
Breiderhoff, T.8
Jansen, P.9
Wu, X.10
-
23
-
-
84863011338
-
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing
-
22279231
-
Fjorback AW, Seaman M, Gustafsen C, Mehmedbasic A, Gokool S, Wu C, Militz D, Schmidt V, Madsen P, Nyengaard JR, et al. Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing. J Neurosci 2012; 32:1467-80; PMID:22279231; http://dx.doi.org/10.1523/JNEUROSCI.2272-11.2012
-
(2012)
J Neurosci
, vol.32
, pp. 1467-1480
-
-
Fjorback, A.W.1
Seaman, M.2
Gustafsen, C.3
Mehmedbasic, A.4
Gokool, S.5
Wu, C.6
Militz, D.7
Schmidt, V.8
Madsen, P.9
Nyengaard, J.R.10
-
24
-
-
84863646688
-
Intracellular amyloid precursor protein sorting and amyloid-beta secretion are regulated by Src-mediated phosphorylation of Mint2
-
22787047
-
Chaufty J, Sullivan SE, Ho A. Intracellular amyloid precursor protein sorting and amyloid-beta secretion are regulated by Src-mediated phosphorylation of Mint2. J Neurosci 2012; 32:9613-25; PMID:22787047; http://dx.doi.org/10.1523/JNEUROSCI.0602-12.2012
-
(2012)
J Neurosci
, vol.32
, pp. 9613-9625
-
-
Chaufty, J.1
Sullivan, S.E.2
Ho, A.3
-
25
-
-
33747878560
-
The X11/Mint family of adaptor proteins
-
16764936
-
Rogelj B, Mitchell JC, Miller CC, McLoughlin DM. The X11/Mint family of adaptor proteins. Brain Res Rev 2006; 52:305-15; PMID:16764936; http://dx.doi.org/10.1016/j.brainresrev.2006.04.005
-
(2006)
Brain Res Rev
, vol.52
, pp. 305-315
-
-
Rogelj, B.1
Mitchell, J.C.2
Miller, C.C.3
McLoughlin, D.M.4
-
26
-
-
2442498577
-
FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein
-
15115822
-
Pietrzik CU, Yoon IS, Jaeger S, Busse T, Weggen S, Koo EH. FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein. J Neurosci 2004; 24:4259-65; PMID:15115822; http://dx.doi.org/10.1523/JNEUROSCI.5451-03.2004
-
(2004)
J Neurosci
, vol.24
, pp. 4259-4265
-
-
Pietrzik, C.U.1
Yoon, I.S.2
Jaeger, S.3
Busse, T.4
Weggen, S.5
Koo, E.H.6
-
27
-
-
84901190201
-
Pharmacological chaperones stabilize retromer to limit APP processing
-
24747528
-
Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. Pharmacological chaperones stabilize retromer to limit APP processing. Nat Chem Biol 2014; 10:443-9; PMID:24747528; http://dx.doi.org/10.1038/nchembio.1508
-
(2014)
Nat Chem Biol
, vol.10
, pp. 443-449
-
-
Mecozzi, V.J.1
Berman, D.E.2
Simoes, S.3
Vetanovetz, C.4
Awal, M.R.5
Patel, V.M.6
Schneider, R.T.7
Petsko, G.A.8
Ringe, D.9
Small, S.A.10
-
28
-
-
77956215864
-
Regulation of amyloid precursor protein processing by the beclin 1 complex
-
20559548
-
Jaeger PA, Pickford F, Sun CH, Lucin KM, Masliah E, Wyss-Coray T. Regulation of amyloid precursor protein processing by the beclin 1 complex. PloS one 2010; 5:e11102; PMID:20559548; http://dx.doi.org/10.1371/journal.pone.0011102
-
(2010)
PloS one
, vol.5
, pp. e11102
-
-
Jaeger, P.A.1
Pickford, F.2
Sun, C.H.3
Lucin, K.M.4
Masliah, E.5
Wyss-Coray, T.6
-
29
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice
-
18497889
-
Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, et al. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 2008; 118:2190-9; PMID:18497889
-
(2008)
J Clin Invest
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
-
30
-
-
84873709314
-
Identification of a candidate therapeutic autophagy-inducing peptide
-
23364696
-
Shoji-Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD, Sun Q, Pallauf K, MacDuff D, et al. Identification of a candidate therapeutic autophagy-inducing peptide. Nature 2013; 494:201-6; PMID:23364696; http://dx.doi.org/10.1038/nature11866
-
(2013)
Nature
, vol.494
, pp. 201-206
-
-
Shoji-Kawata, S.1
Sumpter, R.2
Leveno, M.3
Campbell, G.R.4
Zou, Z.5
Kinch, L.6
Wilkins, A.D.7
Sun, Q.8
Pallauf, K.9
MacDuff, D.10
-
31
-
-
84869147050
-
AKT-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
-
23112296
-
Wang RC, Wei Y, An Z, Zou Z, Xiao G, Bhagat G, White M, Reichelt J, Levine B. AKT-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation. Science 2012; 338:956-9; PMID:23112296; http://dx.doi.org/10.1126/science.1225967
-
(2012)
Science
, vol.338
, pp. 956-959
-
-
Wang, R.C.1
Wei, Y.2
An, Z.3
Zou, Z.4
Xiao, G.5
Bhagat, G.6
White, M.7
Reichelt, J.8
Levine, B.9
-
32
-
-
0033514509
-
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/AKT pathway
-
10051603
-
Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/AKT pathway. Proc Natl Acad Sci U S A 1999; 96:2110-5; PMID:10051603; http://dx.doi.org/10.1073/pnas.96.5.2110
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2110-2115
-
-
Ramaswamy, S.1
Nakamura, N.2
Vazquez, F.3
Batt, D.B.4
Perera, S.5
Roberts, T.M.6
Sellers, W.R.7
-
33
-
-
84890833205
-
BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid beta 42
-
24145555
-
Nah J, Pyo JO, Jung S, Yoo SM, Kam TI, Chang J, Han J, Soo A An S, Onodera T, Jung YK. BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid beta 42. Autophagy 2013; 9:2009-21; PMID:24145555; http://dx.doi.org/10.4161/auto.26118
-
(2013)
Autophagy
, vol.9
, pp. 2009-2021
-
-
Nah, J.1
Pyo, J.O.2
Jung, S.3
Yoo, S.M.4
Kam, T.I.5
Chang, J.6
Han, J.7
Soo A An, S.8
Onodera, T.9
Jung, Y.K.10
-
34
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
17891140
-
Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C, Jung JU, Cheng JQ, Mulé JJ, et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 2007; 9:1142-51; PMID:17891140; http://dx.doi.org/10.1038/ncb1634
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
Cualing, H.D.4
Sun, M.5
Sato, Y.6
Liang, C.7
Jung, J.U.8
Cheng, J.Q.9
Mulé, J.J.10
-
35
-
-
84883499836
-
Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy
-
23878393
-
Fogel AI, Dlouhy BJ, Wang C, Ryu SW, Neutzner A, Hasson SA, Sideris DP, Abeliovich H, Youle RJ. Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy. Mol Cell Biol 2013; 33:3675-88; PMID:23878393; http://dx.doi.org/10.1128/MCB.00079-13
-
(2013)
Mol Cell Biol
, vol.33
, pp. 3675-3688
-
-
Fogel, A.I.1
Dlouhy, B.J.2
Wang, C.3
Ryu, S.W.4
Neutzner, A.5
Hasson, S.A.6
Sideris, D.P.7
Abeliovich, H.8
Youle, R.J.9
-
36
-
-
84862777560
-
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
-
22310240
-
Huang W, Choi W, Hu W, Mi N, Guo Q, Ma M, Liu M, Tian Y, Lu P, Wang FL, et al. Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein. Cell Res 2012; 22:473-89; PMID:22310240; http://dx.doi.org/10.1038/cr.2012.24
-
(2012)
Cell Res
, vol.22
, pp. 473-489
-
-
Huang, W.1
Choi, W.2
Hu, W.3
Mi, N.4
Guo, Q.5
Ma, M.6
Liu, M.7
Tian, Y.8
Lu, P.9
Wang, F.L.10
-
37
-
-
84861663288
-
Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner
-
22496425
-
Bejarano E, Girao H, Yuste A, Patel B, Marques C, Spray DC, Pereira P, Cuervo AM. Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner. Mol Biol Cell 2012; 23:2156-69; PMID:22496425; http://dx.doi.org/10.1091/mbc.E11-10-0844
-
(2012)
Mol Biol Cell
, vol.23
, pp. 2156-2169
-
-
Bejarano, E.1
Girao, H.2
Yuste, A.3
Patel, B.4
Marques, C.5
Spray, D.C.6
Pereira, P.7
Cuervo, A.M.8
-
38
-
-
84883464875
-
Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism
-
23954414
-
He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, et al. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell 2013; 154:1085-99; PMID:23954414; http://dx.doi.org/10.1016/j.cell.2013.07.035
-
(2013)
Cell
, vol.154
, pp. 1085-1099
-
-
He, C.1
Wei, Y.2
Sun, K.3
Li, B.4
Dong, X.5
Zou, Z.6
Liu, Y.7
Kinch, L.N.8
Khan, S.9
Sinha, S.10
-
39
-
-
84874998766
-
The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease
-
Ihara Y, Morishima-Kawashima M, Nixon R. The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease. Cold Spring Harbor Perspect Med 2012; 2:a006361; http://dx.doi.org/10.1101/cshperspect.a006361
-
(2012)
Cold Spring Harbor Perspect Med
, vol.2
-
-
Ihara, Y.1
Morishima-Kawashima, M.2
Nixon, R.3
-
40
-
-
79955964504
-
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
-
21081164
-
Rohn TT, Wirawan E, Brown RJ, Harris JR, Masliah E, Vandenabeele P. Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol Dis 2011; 43:68-78; PMID:21081164; http://dx.doi.org/10.1016/j.nbd.2010.11.003
-
(2011)
Neurobiol Dis
, vol.43
, pp. 68-78
-
-
Rohn, T.T.1
Wirawan, E.2
Brown, R.J.3
Harris, J.R.4
Masliah, E.5
Vandenabeele, P.6
-
41
-
-
84881324927
-
Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system
-
23907271
-
Morel E, Chamoun Z, Lasiecka ZM, Chan RB, Williamson RL, Vetanovetz C, Dall'Armi C, Simoes S, Point Du Jour KS, McCabe BD, et al. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. Nat Commun 2013; 4:2250; PMID:23907271; http://dx.doi.org/10.1038/ncomms3250
-
(2013)
Nat Commun
, vol.4
, pp. 2250
-
-
Morel, E.1
Chamoun, Z.2
Lasiecka, Z.M.3
Chan, R.B.4
Williamson, R.L.5
Vetanovetz, C.6
Dall'Armi, C.7
Simoes, S.8
Point Du Jour, K.S.9
McCabe, B.D.10
-
42
-
-
84884185631
-
Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease
-
24012002
-
Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ, Mastroeni DF, Rogers J, Spencer B, Masliah E, et al. Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron 2013; 79:873-86; PMID:24012002; http://dx.doi.org/10.1016/j.neuron.2013.06.046
-
(2013)
Neuron
, vol.79
, pp. 873-886
-
-
Lucin, K.M.1
O'Brien, C.E.2
Bieri, G.3
Czirr, E.4
Mosher, K.I.5
Abbey, R.J.6
Mastroeni, D.F.7
Rogers, J.8
Spencer, B.9
Masliah, E.10
-
43
-
-
84907170338
-
GA binding protein augments autophagy via transcriptional activation of BECN1-PIK3C3 complex genes
-
25046113
-
Zhu W, Swaminathan G, Plowey ED. GA binding protein augments autophagy via transcriptional activation of BECN1-PIK3C3 complex genes. Autophagy 2014; 10:1622-36; PMID:25046113; http://dx.doi.org/10.4161/auto.29454
-
(2014)
Autophagy
, vol.10
, pp. 1622-1636
-
-
Zhu, W.1
Swaminathan, G.2
Plowey, E.D.3
-
44
-
-
2342558065
-
AKT activity in Alzheimer's disease and other neurodegenerative disorders
-
15076714
-
Rickle A, Bogdanovic N, Volkman I, Winblad B, Ravid R, Cowburn RF. AKT activity in Alzheimer's disease and other neurodegenerative disorders. Neuroreport 2004; 15:955-9; PMID:15076714; http://dx.doi.org/10.1097/00001756-200404290-00005
-
(2004)
Neuroreport
, vol.15
, pp. 955-959
-
-
Rickle, A.1
Bogdanovic, N.2
Volkman, I.3
Winblad, B.4
Ravid, R.5
Cowburn, R.F.6
-
45
-
-
16244391770
-
Activation of AKT/PKB, increased phosphorylation of AKT substrates and loss and altered distribution of AKT and PTEN are features of Alzheimer's disease pathology
-
15773910
-
Griffin RJ, Moloney A, Kelliher M, Johnston JA, Ravid R, Dockery P, O'Connor R, O'Neill C. Activation of AKT/PKB, increased phosphorylation of AKT substrates and loss and altered distribution of AKT and PTEN are features of Alzheimer's disease pathology. J Neurochem 2005; 93:105-17; PMID:15773910; http://dx.doi.org/10.1111/j.1471-4159.2004.02949.x
-
(2005)
J Neurochem
, vol.93
, pp. 105-117
-
-
Griffin, R.J.1
Moloney, A.2
Kelliher, M.3
Johnston, J.A.4
Ravid, R.5
Dockery, P.6
O'Connor, R.7
O'Neill, C.8
-
46
-
-
66049094854
-
Constitutively active AKT inhibits trafficking of amyloid precursor protein and amyloid precursor protein metabolites through feedback inhibition of phosphoinositide 3-kinase
-
19236051
-
Shineman DW, Dain AS, Kim ML, Lee VM. Constitutively active AKT inhibits trafficking of amyloid precursor protein and amyloid precursor protein metabolites through feedback inhibition of phosphoinositide 3-kinase. Biochemistry 2009; 48:3787-94; PMID:19236051; http://dx.doi.org/10.1021/bi802070j
-
(2009)
Biochemistry
, vol.48
, pp. 3787-3794
-
-
Shineman, D.W.1
Dain, A.S.2
Kim, M.L.3
Lee, V.M.4
-
47
-
-
77955131007
-
Plasma membrane contributes to the formation of pre-autophagosomal structures
-
20639872
-
Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC. Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat Cell Biol 2010; 12:747-57; PMID:20639872; http://dx.doi.org/10.1038/ncb2078
-
(2010)
Nat Cell Biol
, vol.12
, pp. 747-757
-
-
Ravikumar, B.1
Moreau, K.2
Jahreiss, L.3
Puri, C.4
Rubinsztein, D.C.5
-
48
-
-
37549040612
-
A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference
-
18160654
-
Young-Pearse TL, Bai J, Chang R, Zheng JB, LoTurco JJ, Selkoe DJ. A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J Neurosci 2007; 27:14459-69; PMID:18160654; http://dx.doi.org/10.1523/JNEUROSCI.4701-07.2007
-
(2007)
J Neurosci
, vol.27
, pp. 14459-14469
-
-
Young-Pearse, T.L.1
Bai, J.2
Chang, R.3
Zheng, J.B.4
LoTurco, J.J.5
Selkoe, D.J.6
-
49
-
-
29244449301
-
Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3
-
16249233
-
Falcon-Perez JM, Nazarian R, Sabatti C, Dell'Angelica EC. Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3. J Cell Sci 2005; 118:5243-55; PMID:16249233; http://dx.doi.org/10.1242/jcs.02633
-
(2005)
J Cell Sci
, vol.118
, pp. 5243-5255
-
-
Falcon-Perez, J.M.1
Nazarian, R.2
Sabatti, C.3
Dell'Angelica, E.C.4
-
50
-
-
0034602964
-
The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization
-
10652369
-
Lawe DC, Patki V, Heller-Harrison R, Lambright D, Corvera S. The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization. J Biol Chem 2000; 275:3699-705; PMID:10652369; http://dx.doi.org/10.1074/jbc.275.5.3699
-
(2000)
J Biol Chem
, vol.275
, pp. 3699-3705
-
-
Lawe, D.C.1
Patki, V.2
Heller-Harrison, R.3
Lambright, D.4
Corvera, S.5
-
51
-
-
0036083829
-
Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells
-
12070301
-
Choudhury A, Dominguez M, Puri V, Sharma DK, Narita K, Wheatley CL, Marks DL, Pagano RE. Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells. J Clin Invest 2002; 109:1541-50; PMID:12070301; http://dx.doi.org/10.1172/JCI0215420
-
(2002)
J Clin Invest
, vol.109
, pp. 1541-1550
-
-
Choudhury, A.1
Dominguez, M.2
Puri, V.3
Sharma, D.K.4
Narita, K.5
Wheatley, C.L.6
Marks, D.L.7
Pagano, R.E.8
-
52
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Bio Cell 2008; 19:2092-100; http://dx.doi.org/10.1091/mbc.E07-12-1257
-
(2008)
Mol Bio Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
53
-
-
0035494493
-
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation
-
11581283
-
Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, Davidson HW, Schreiber A, Backer JM, Cantley LC, Grinstein S. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J Cell Biol 2001; 155:19-25; PMID:11581283; http://dx.doi.org/10.1083/jcb.200107069
-
(2001)
J Cell Biol
, vol.155
, pp. 19-25
-
-
Vieira, O.V.1
Botelho, R.J.2
Rameh, L.3
Brachmann, S.M.4
Matsuo, T.5
Davidson, H.W.6
Schreiber, A.7
Backer, J.M.8
Cantley, L.C.9
Grinstein, S.10
|