메뉴 건너뛰기




Volumn 9, Issue 12, 2013, Pages 2009-2021

BECN1/Beclin1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid β 42

Author keywords

Amyloid beta; Autophagy; BECN1; Lipid rafts; Prion protein

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BECLIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PRION PROTEIN; PROTEIN BCL 2; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; MEMBRANE PROTEIN; PEPTIDE FRAGMENT; PRNP PROTEIN, HUMAN;

EID: 84890833205     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.26118     Document Type: Article
Times cited : (36)

References (45)
  • 1
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • PMID:15068787
    • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6:463-77; PMID:15068787; http://dx.doi.org/10.1016/S1534-5807(04)00099-1
    • (2004) Dev Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 3
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macroautophagy
    • PMID:20811353
    • Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol 2010; 12:814-22; PMID:20811353; http://dx.doi.org/10.1038/ncb0910-814
    • (2010) Nat Cell Biol , vol.12 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 4
    • 0001488499 scopus 로고    scopus 로고
    • Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
    • PMID:9765397
    • Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998; 72:8586-96; PMID:9765397
    • (1998) J Virol , vol.72 , pp. 8586-8596
    • Liang, X.H.1    Kleeman, L.K.2    Jiang, H.H.3    Gordon, G.4    Goldman, J.E.5    Berry, G.6    Herman, B.7    Levine, B.8
  • 5
    • 77953543377 scopus 로고    scopus 로고
    • The Beclin 1-VPS34 complex - At the crossroads of autophagy and beyond
    • PMID:20356743
    • Funderburk SF, Wang Q J, Yue Z. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol 2010; 20:355-62; PMID:20356743; http://dx.doi.org/10.1016/j.tcb.2010.03.002
    • (2010) Trends Cell Biol , vol.20 , pp. 355-362
    • Funderburk, S.F.1    Wang, Q.J.2    Yue, Z.3
  • 8
    • 0023663071 scopus 로고
    • Scrapie prion protein contains a phosphatidylinositol glycolipid
    • PMID:2444340
    • Stahl N, Borchelt DR, Hsiao K, Prusiner SB. Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 1987; 51:229-40; PMID:2444340; http://dx.doi.org/10.1016/0092-8674(87)90150-4
    • (1987) Cell , vol.51 , pp. 229-240
    • Stahl, N.1    Borchelt, D.R.2    Hsiao, K.3    Prusiner, S.B.4
  • 9
    • 84857128506 scopus 로고    scopus 로고
    • Cellular prion and its catabolites in the brain: Production and function
    • PMID:22272726
    • Guillot-Sestier MV, Checler F. Cellular prion and its catabolites in the brain: production and function. Curr Mol Med 2012; 12:304-15; PMID:22272726; http://dx.doi.org/10.2174/156652412799218912
    • (2012) Curr Mol Med , vol.12 , pp. 304-315
    • Guillot-Sestier, M.V.1    Checler, F.2
  • 12
    • 33646695909 scopus 로고    scopus 로고
    • Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury
    • PMID:16574930
    • Weise J, Sandau R, Schwarting S, Crome O, Wrede A, Schulz-Schaeffer W, Zerr I, Bähr M. Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury. Stroke 2006; 37:1296-300; PMID:16574930; http://dx.doi.org/10.1161/01.STR.0000217262.03192.d4
    • (2006) Stroke , vol.37 , pp. 1296-1300
    • Weise, J.1    Sandau, R.2    Schwarting, S.3    Crome, O.4    Wrede, A.5    Schulz-Schaeffer, W.6    Zerr, I.7    Bähr, M.8
  • 13
    • 72149127389 scopus 로고    scopus 로고
    • The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo
    • PMID:19850936
    • Guillot-Sestier MV, Sunyach C, Druon C, Scarzello S, Checler F. The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo. J Biol Chem 2009; 284:35973-86; PMID:19850936; http://dx.doi.org/10.1074/jbc.M109.051086
    • (2009) J Biol Chem , vol.284 , pp. 35973-35986
    • Guillot-Sestier, M.V.1    Sunyach, C.2    Druon, C.3    Scarzello, S.4    Checler, F.5
  • 15
    • 0028052363 scopus 로고
    • Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
    • PMID:8287472
    • Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, Yang SL, Torchia M, Carlson GA, Prusiner SB. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell 1994; 76:117-29; PMID:8287472; http://dx.doi.org/10.1016/0092-8674(94)90177-5
    • (1994) Cell , vol.76 , pp. 117-129
    • Westaway, D.1    DeArmond, S.J.2    Cayetano-Canlas, J.3    Groth, D.4    Foster, D.5    Yang, S.L.6    Torchia, M.7    Carlson, G.A.8    Prusiner, S.B.9
  • 16
    • 33645290776 scopus 로고    scopus 로고
    • The prion protein and lipid rafts
    • PMID:16611584
    • Taylor DR, Hooper NM. The prion protein and lipid rafts. Mol Membr Biol 2006; 23:89-99; PMID:16611584; http://dx.doi.org/10.1080/09687860500449994
    • (2006) Mol Membr Biol , vol.23 , pp. 89-99
    • Taylor, D.R.1    Hooper, N.M.2
  • 17
    • 56249124005 scopus 로고    scopus 로고
    • Lipid rafts, cholesterol, and the brain
    • PMID:18402986
    • Korade Z, Kenworthy AK. Lipid rafts, cholesterol, and the brain. Neuropharmacology 2008; 55:1265-73; PMID:18402986; http://dx.doi.org/10.1016/j. neuropharm.2008.02.019
    • (2008) Neuropharmacology , vol.55 , pp. 1265-1273
    • Korade, Z.1    Kenworthy, A.K.2
  • 19
    • 0031436335 scopus 로고    scopus 로고
    • The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells
    • PMID:9396609
    • Rieger R, Edenhofer F, Lasmézas CI, Weiss S. The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells. Nat Med 1997; 3:1383-8; PMID:9396609; http://dx.doi.org/10.1038/nm1297-1383
    • (1997) Nat Med , vol.3 , pp. 1383-1388
    • Rieger, R.1    Edenhofer, F.2    Lasmézas, C.I.3    Weiss, S.4
  • 20
    • 0035977053 scopus 로고    scopus 로고
    • PrPC directly interacts with proteins involved in signaling pathways
    • PMID:11571277
    • Spielhaupter C, Schätzl HM. PrPC directly interacts with proteins involved in signaling pathways. J Biol Chem 2001; 276:44604-12; PMID:11571277; http://dx.doi.org/10.1074/jbc.M103289200
    • (2001) J Biol Chem , vol.276 , pp. 44604-44612
    • Spielhaupter, C.1    Schätzl, H.M.2
  • 21
    • 61349201380 scopus 로고    scopus 로고
    • Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
    • PMID:19242475
    • Laurén J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 2009; 457:1128-32; PMID:19242475; http://dx.doi.org/10.1038/nature07761
    • (2009) Nature , vol.457 , pp. 1128-1132
    • Laurén, J.1    Gimbel, D.A.2    Nygaard, H.B.3    Gilbert, J.W.4    Strittmatter, S.M.5
  • 22
    • 0041664024 scopus 로고    scopus 로고
    • Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line
    • PMID:12914801
    • Sakudo A, Lee DC, Saeki K, Nakamura Y, Inoue K, Matsumoto Y, Itohara S, Onodera T. Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line. Biochem Biophys Res Commun 2003; 308:660-7; PMID:12914801; http://dx.doi.org/10.1016/ S0006-291X(03)01459-1
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 660-667
    • Sakudo, A.1    Lee, D.C.2    Saeki, K.3    Nakamura, Y.4    Inoue, K.5    Matsumoto, Y.6    Itohara, S.7    Onodera, T.8
  • 23
    • 34548259958 scopus 로고    scopus 로고
    • p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • PMID:17580304
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45; PMID:17580304; http://dx.doi.org/10.1074/jbc.M702824200
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6    Øvervatn, A.7    Bjørkøy, G.8    Johansen, T.9
  • 24
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • PMID:20144757
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140:313-26; PMID:20144757; http://dx.doi.org/10.1016/j. cell.2010.01.028
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 25
    • 37649024076 scopus 로고    scopus 로고
    • Small molecule regulators of autophagy identified by an image-based high-throughput screen
    • PMID:18024584
    • Zhang L, Yu J, Pan H, Hu P, Hao Y, Cai W, Zhu H, Yu AD, Xie X, Ma D, et al. Small molecule regulators of autophagy identified by an image-based high-throughput screen. Proc Natl Acad Sci U S A 2007; 104:19023-8; PMID:18024584; http://dx.doi.org/10.1073/pnas.0709695104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19023-19028
    • Zhang, L.1    Yu, J.2    Pan, H.3    Hu, P.4    Hao, Y.5    Cai, W.6    Zhu, H.7    Yu, A.D.8    Xie, X.9    Ma, D.10
  • 26
    • 0029741379 scopus 로고    scopus 로고
    • Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin
    • PMID:8861953
    • Bastiaens PI, Majoul IV, Verveer PJ, Söling HD, Jovin TM. Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin. EMBO J 1996; 15:4246-53; PMID:8861953
    • (1996) EMBO J , vol.15 , pp. 4246-4253
    • Bastiaens, P.I.1    Majoul, I.V.2    Verveer, P.J.3    Söling, H.D.4    Jovin, T.M.5
  • 27
    • 0034613294 scopus 로고    scopus 로고
    • Age-related decline in chaperone-mediated autophagy
    • PMID:10806201
    • Cuervo AM, Dice JF. Age-related decline in chaperone-mediated autophagy. J Biol Chem 2000; 275:31505-13; PMID:10806201; http://dx.doi.org/10.1074/jbc. M002102200
    • (2000) J Biol Chem , vol.275 , pp. 31505-31513
    • Cuervo, A.M.1    Dice, J.F.2
  • 28
    • 0028572459 scopus 로고
    • Alzheimer's disease, beta-amyloidosis, and aging
    • PMID:7697197
    • Coria F, Rubio I, Bayón C. Alzheimer's disease, beta-amyloidosis, and aging. Rev Neurosci 1994; 5:275-92; PMID:7697197; http://dx.doi.org/10.1515/ REVNEURO.1994.5.4.275
    • (1994) Rev Neurosci , vol.5 , pp. 275-292
    • Coria, F.1    Rubio, I.2    Bayón, C.3
  • 29
    • 0024806367 scopus 로고
    • Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes
    • PMID:2598927
    • Ohtani Y, Irie T, Uekama K, Fukunaga K, Pitha J. Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes. Eur J Biochem 1989; 186:17-22; PMID:2598927; http://dx.doi.org/10.1111/j.1432-1033.1989.tb15171.x
    • (1989) Eur J Biochem , vol.186 , pp. 17-22
    • Ohtani, Y.1    Irie, T.2    Uekama, K.3    Fukunaga, K.4    Pitha, J.5
  • 30
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • PMID:21311563
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18:571-80; PMID:21311563; http://dx.doi.org/10.1038/cdd.2010.191
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 31
    • 50249084987 scopus 로고    scopus 로고
    • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    • PMID:18725538
    • Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182:685-701; PMID:18725538; http://dx.doi.org/10.1083/jcb.200803137
    • (2008) J Cell Biol , vol.182 , pp. 685-701
    • Axe, E.L.1    Walker, S.A.2    Manifava, M.3    Chandra, P.4    Roderick, H.L.5    Habermann, A.6    Griffiths, G.7    Ktistakis, N.T.8
  • 32
    • 84858336588 scopus 로고    scopus 로고
    • Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling
    • Son SM, Jung ES, Shin HJ, Byun J, Mook-Jung I. Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling. Neurobiol Aging 2012; 33:1006.e11-23; http://dx.doi.org/10.1016/j.neurobiolaging.2011.09. 039
    • (2012) Neurobiol Aging , vol.33
    • Son, S.M.1    Jung, E.S.2    Shin, H.J.3    Byun, J.4    Mook-Jung, I.5
  • 34
    • 42449158007 scopus 로고    scopus 로고
    • Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies)
    • PMID:18368623
    • Liberski PP, Brown DR, Sikorska B, Caughey B, Brown P. Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). Folia Neuropathol 2008; 46:1-25; PMID:18368623
    • (2008) Folia Neuropathol , vol.46 , pp. 1-25
    • Liberski, P.P.1    Brown, D.R.2    Sikorska, B.3    Caughey, B.4    Brown, P.5
  • 35
    • 84857408200 scopus 로고    scopus 로고
    • Highly neurotoxic monomeric α-helical prion protein
    • PMID:22323583
    • Zhou M, Ottenberg G, Sferrazza GF, Lasmézas CI. Highly neurotoxic monomeric α-helical prion protein. Proc Natl Acad Sci U S A 2012; 109:3113-8; PMID:22323583; http://dx.doi.org/10.1073/pnas.1118090109
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 3113-3118
    • Zhou, M.1    Ottenberg, G.2    Sferrazza, G.F.3    Lasmézas, C.I.4
  • 36
    • 52049108464 scopus 로고    scopus 로고
    • The involvement of cellular prion protein in the autophagy pathway in neuronal cells
    • PMID:18674620
    • Oh JM, Shin HY, Park SJ, Kim BH, Choi JK, Choi EK, Carp RI, Kim YS. The involvement of cellular prion protein in the autophagy pathway in neuronal cells. Mol Cell Neurosci 2008; 39:238-47; PMID:18674620; http://dx.doi.org/10. 1016/j.mcn.2008.07.003
    • (2008) Mol Cell Neurosci , vol.39 , pp. 238-247
    • Oh, J.M.1    Shin, H.Y.2    Park, S.J.3    Kim, B.H.4    Choi, J.K.5    Choi, E.K.6    Carp, R.I.7    Kim, Y.S.8
  • 37
    • 71549115512 scopus 로고    scopus 로고
    • Autophagy and cell death of Purkinje cells overexpressing Doppel in Ngsk Prnp-deficient mice
    • PMID:19055638
    • Heitz S, Grant NJ, Leschiera R, Haeberlé AM, Demais V, Bombarde G, Bailly Y. Autophagy and cell death of Purkinje cells overexpressing Doppel in Ngsk Prnp-deficient mice. Brain Pathol 2010; 20:119-32; PMID:19055638; http://dx.doi.org/10.1111/j.1750-3639.2008.00245.x
    • (2010) Brain Pathol , vol.20 , pp. 119-132
    • Heitz, S.1    Grant, N.J.2    Leschiera, R.3    Haeberlé, A.M.4    Demais, V.5    Bombarde, G.6    Bailly, Y.7
  • 38
    • 84867278754 scopus 로고    scopus 로고
    • Oxidative stress impairs autophagic flux in prion protein-deficient hippocampal cells
    • PMID:22889724
    • Oh JM, Choi EK, Carp RI, Kim YS. Oxidative stress impairs autophagic flux in prion protein-deficient hippocampal cells. Autophagy 2012; 8:1448-61; PMID:22889724; http://dx.doi.org/10.4161/auto.21164
    • (2012) Autophagy , vol.8 , pp. 1448-1461
    • Oh, J.M.1    Choi, E.K.2    Carp, R.I.3    Kim, Y.S.4
  • 40
    • 38949099761 scopus 로고    scopus 로고
    • Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
    • PMID:18059160
    • Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD. Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 2008; 4:176-84; PMID:18059160
    • (2008) Autophagy , vol.4 , pp. 176-184
    • Simonsen, A.1    Cumming, R.C.2    Brech, A.3    Isakson, P.4    Schubert, D.R.5    Finley, K.D.6
  • 41
    • 0034790685 scopus 로고    scopus 로고
    • Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells
    • PMID:11595760
    • Lee KS, Magalhães AC, Zanata SM, Brentani RR, Martins VR, Prado MA. Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells. J Neurochem 2001; 79:79-87; PMID:11595760; http://dx.doi.org/10.1046/j.1471-4159.2001.00529.x
    • (2001) J Neurochem , vol.79 , pp. 79-87
    • Lee, K.S.1    Magalhães, A.C.2    Zanata, S.M.3    Brentani, R.R.4    Martins, V.R.5    Prado, M.A.6
  • 42
    • 41449084234 scopus 로고    scopus 로고
    • Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death
    • PMID:18196969
    • Pyo JO, Nah J, Kim HJ, Lee HJ, Heo J, Lee H, Jung YK. Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. Autophagy 2008; 4:315-21; PMID:18196969
    • (2008) Autophagy , vol.4 , pp. 315-321
    • Pyo, J.O.1    Nah, J.2    Kim, H.J.3    Lee, H.J.4    Heo, J.5    Lee, H.6    Jung, Y.K.7
  • 44
    • 7244258941 scopus 로고    scopus 로고
    • Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes
    • PMID:15322084
    • Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. J Biol Chem 2004; 279:44945-54; PMID:15322084; http://dx.doi.org/10.1074/jbc.M407986200
    • (2004) J Biol Chem , vol.279 , pp. 44945-44954
    • Vetrivel, K.S.1    Cheng, H.2    Lin, W.3    Sakurai, T.4    Li, T.5    Nukina, N.6    Wong, P.C.7    Xu, H.8    Thinakaran, G.9
  • 45
    • 0030896414 scopus 로고    scopus 로고
    • Isolation and culture of adult rat hippocampal neurons
    • PMID:9128149
    • Brewer GJ. Isolation and culture of adult rat hippocampal neurons. J Neurosci Methods 1997; 71:143-55; PMID:9128149; http://dx.doi.org/10.1016/S0165- 0270(96)00136-7
    • (1997) J Neurosci Methods , vol.71 , pp. 143-155
    • Brewer, G.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.