Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG

Nature Communications

Volumn 3, Issue , 2012, Pages

  Li, Xiaohua ^a   He, Liqiang ^b   Che, Ka Hing ^a   Funderburk, Sarah F ^b   Pan, Lifeng ^c   Pan, Nina ^b   Zhang, Mingjie ^c   Yue, Zhenyu ^b   Zhao, Yanxiang ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; HETERODIMER; HOMODIMER; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ATG14L; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; ATG14 PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; MEMBRANE PROTEIN; TUMOR SUPPRESSOR PROTEIN; UVRAG PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ARTICLE; AUTOPHAGY; COILED BODY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MECHANISM; HUMAN; HUMAN CELL; MODULATION; MUTANT; NONHUMAN; PROTEIN FUNCTION; AMINO ACID SEQUENCE; CELL STRAIN HEK293; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DIMERIZATION; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MUTATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STATIC ELECTRICITY; TEMPERATURE; X RAY CRYSTALLOGRAPHY;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CLASS III PHOSPHATIDYLINOSITOL 3-KINASES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; STATIC ELECTRICITY; TEMPERATURE; TUMOR SUPPRESSOR PROTEINS;

EID: 84862023791     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1648     Document Type: Article

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