메뉴 건너뛰기




Volumn 288, Issue 28, 2013, Pages 20315-20325

Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation

Author keywords

[No Author keywords available]

Indexed keywords

AKT PHOSPHORYLATION; BREAST CARCINOMA CELLS; CELL-SURFACE INTERACTIONS; KEY REGULATORS; MEMBRANE ANCHORS; NEW MECHANISMS; PROTEIN TYROSINE KINASE; RECIPROCAL REGULATION;

EID: 84880061812     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.461350     Document Type: Article
Times cited : (53)

References (50)
  • 1
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer, G., Mariño, G., and Levine, B. (2010) Autophagy and the integrated stress response. Mol. Cell 40, 280-293
    • (2010) Mol. Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Mariño, G.2    Levine, B.3
  • 3
    • 79954417611 scopus 로고    scopus 로고
    • Autophagy for tissue homeostasis and neuroprotection
    • Mariño, G., Madeo, F., and Kroemer, G. (2011) Autophagy for tissue homeostasis and neuroprotection. Curr. Opin. Cell Biol. 23, 198-206
    • (2011) Curr. Opin. Cell Biol. , vol.23 , pp. 198-206
    • Mariño, G.1    Madeo, F.2    Kroemer, G.3
  • 4
    • 84856431622 scopus 로고    scopus 로고
    • The end of autophagic cell death?
    • Shen, S., Kepp, O., and Kroemer, G. (2012) The end of autophagic cell death? Autophagy 8, 1-3
    • (2012) Autophagy , vol.8 , pp. 1-3
    • Shen, S.1    Kepp, O.2    Kroemer, G.3
  • 5
    • 21444442926 scopus 로고    scopus 로고
    • Radiation-induced autophagy is associated with LC3, and its inhibition sensitizes malignant glioma cells
    • Ito, H., Daido, S., Kanzawa, T., Kondo, S., and Kondo, Y. (2005) Radiation-induced autophagy is associated with LC3, and its inhibition sensitizes malignant glioma cells. Int. J. Oncol. 26, 1401-1410
    • (2005) Int. J. Oncol. , vol.26 , pp. 1401-1410
    • Ito, H.1    Daido, S.2    Kanzawa, T.3    Kondo, S.4    Kondo, Y.5
  • 6
    • 40449086885 scopus 로고    scopus 로고
    • Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
    • DOI 10.1158/0008-5472.CAN-07-0562
    • Apel, A., Herr, I., Schwarz, H., Rodemann, H. P., and Mayer, A. (2008) Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res. 68, 1485-1494 (Pubitemid 351346857)
    • (2008) Cancer Research , vol.68 , Issue.5 , pp. 1485-1494
    • Apel, A.1    Herr, I.2    Schwarz, H.3    Rodemann, H.P.4    Mayer, A.5
  • 10
    • 79956224883 scopus 로고    scopus 로고
    • Targeting autophagy during cancer therapy to improve clinical outcomes
    • Levy, J. M., and Thorburn, A. (2011) Targeting autophagy during cancer therapy to improve clinical outcomes. Pharmacol. Ther. 131, 130-141
    • (2011) Pharmacol. Ther. , vol.131 , pp. 130-141
    • Levy, J.M.1    Thorburn, A.2
  • 11
    • 60449092595 scopus 로고    scopus 로고
    • Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells
    • Li, J., Hou, N., Faried, A., Tsutsumi, S., Takeuchi, T., and Kuwano, H. (2009) Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Ann. Surg. Oncol. 16, 761-771
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 761-771
    • Li, J.1    Hou, N.2    Faried, A.3    Tsutsumi, S.4    Takeuchi, T.5    Kuwano, H.6
  • 13
    • 50349098812 scopus 로고    scopus 로고
    • Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells
    • Han, J., Hou, W., Goldstein, L. A., Lu, C., Stolz, D. B., Yin, X. M., and Rabinowich, H. (2008) Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. J. Biol. Chem. 283, 19665-19677
    • (2008) J. Biol. Chem. , vol.283 , pp. 19665-19677
    • Han, J.1    Hou, W.2    Goldstein, L.A.3    Lu, C.4    Stolz, D.B.5    Yin, X.M.6    Rabinowich, H.7
  • 15
    • 53549092494 scopus 로고    scopus 로고
    • Enhancement of tumor-TRAIL susceptibility by modulation of autophagy
    • Hou, W., Han, J., Lu, C., Goldstein, L. A., and Rabinowich, H. (2008) Enhancement of tumor-TRAIL susceptibility by modulation of autophagy. Autophagy 4, 940-943
    • (2008) Autophagy , vol.4 , pp. 940-943
    • Hou, W.1    Han, J.2    Lu, C.3    Goldstein, L.A.4    Rabinowich, H.5
  • 17
    • 80051699683 scopus 로고    scopus 로고
    • Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: A beneficial strategy to combat non-small cell lung cancer
    • Gorzalczany, Y., Gilad, Y., Amihai, D., Hammel, I., Sagi-Eisenberg, R., and Merimsky, O. (2011) Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: a beneficial strategy to combat non-small cell lung cancer. Cancer Lett. 310, 207-215
    • (2011) Cancer Lett. , vol.310 , pp. 207-215
    • Gorzalczany, Y.1    Gilad, Y.2    Amihai, D.3    Hammel, I.4    Sagi-Eisenberg, R.5    Merimsky, O.6
  • 18
    • 79957963599 scopus 로고    scopus 로고
    • EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells
    • Han, W., Pan, H., Chen, Y., Sun, J., Wang, Y., Li, J., Ge, W., Feng, L., Lin, X., Wang, X., Wang, X., and Jin, H. (2011) EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS One 6, e18691
    • (2011) PLoS One , vol.6
    • Han, W.1    Pan, H.2    Chen, Y.3    Sun, J.4    Wang, Y.5    Li, J.6    Ge, W.7    Feng, L.8    Lin, X.9    Wang, X.10    Wang, X.11    Jin, H.12
  • 21
    • 79951505692 scopus 로고    scopus 로고
    • Inhibition of autophagy: A new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors
    • Calabretta, B., and Salomoni, P. (2011) Inhibition of autophagy: a new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors. Leuk. Lymphoma 52, Suppl. 1, 54-59
    • (2011) Leuk. Lymphoma , vol.52 , Issue.SUPPL. 1 , pp. 54-59
    • Calabretta, B.1    Salomoni, P.2
  • 23
    • 1342323632 scopus 로고    scopus 로고
    • ErbB Receptors: Directing Key Signaling Networks Throughout Life
    • DOI 10.1146/annurev.pharmtox.44.101802.121440
    • Holbro, T., and Hynes, N. E. (2004) ErbB receptors: directing key signaling networks throughout life. Annu. Rev. Pharmacol. Toxicol. 44, 195-217 (Pubitemid 38263839)
    • (2004) Annual Review of Pharmacology and Toxicology , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 24
    • 84860870716 scopus 로고    scopus 로고
    • Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization
    • Shan, Y., Eastwood, M. P., Zhang, X., Kim, E. T., Arkhipov, A., Dror, R. O., Jumper, J., Kuriyan, J., and Shaw, D. E. (2012) Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization. Cell 149, 860-870
    • (2012) Cell , vol.149 , pp. 860-870
    • Shan, Y.1    Eastwood, M.P.2    Zhang, X.3    Kim, E.T.4    Arkhipov, A.5    Dror, R.O.6    Jumper, J.7    Kuriyan, J.8    Shaw, D.E.9
  • 25
    • 84055207507 scopus 로고    scopus 로고
    • Lapatinib induces autophagy, apoptosis, and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells
    • Huang, H. L., Chen, Y. C., Huang, Y. C., Yang, K. C., Pan, H. y., Shih, S. P., and Chen, Y. J. (2011) Lapatinib induces autophagy, apoptosis, and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells. PloS one 6, e29014
    • (2011) PloS One , vol.6
    • Huang, H.L.1    Chen, Y.C.2    Huang, Y.C.3    Yang, K.C.4    Pan, H.Y.5    Shih, S.P.6    Chen, Y.J.7
  • 26
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • DOI 10.1038/nature06639, PII NATURE06639
    • Mizushima, N., Levine, B., Cuervo, A. M., and Klionsky, D. J. (2008) Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075 (Pubitemid 351317450)
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 27
    • 79251577061 scopus 로고    scopus 로고
    • The regulation of autophagy - Unanswered questions
    • Chen, Y., and Klionsky, D. J. (2011) The regulation of autophagy - unanswered questions. J. Cell Sci. 124, 161-170
    • (2011) J. Cell Sci. , vol.124 , pp. 161-170
    • Chen, Y.1    Klionsky, D.J.2
  • 28
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • Itakura, E., Kishi, C., Inoue, K., and Mizushima, N. (2008) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol. Biol. Cell 19, 5360-5372
    • (2008) Mol. Biol. Cell , vol.19 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 30
    • 64049113909 scopus 로고    scopus 로고
    • Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
    • Zhong, Y., Wang, Q. J., Li, X., Yan, Y., Backer, J. M., Chait, B. T., Heintz, N., and Yue, Z. (2009) Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat. Cell Biol. 11, 468-476
    • (2009) Nat. Cell Biol. , vol.11 , pp. 468-476
    • Zhong, Y.1    Wang, Q.J.2    Li, X.3    Yan, Y.4    Backer, J.M.5    Chait, B.T.6    Heintz, N.7    Yue, Z.8
  • 33
    • 84869147050 scopus 로고    scopus 로고
    • Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
    • Wang, R. C., Wei, Y., An, Z., Zou, Z., Xiao, G., Bhagat, G., White, M., Reichelt, J., and Levine, B. (2012) Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation. Science 338, 956-959
    • (2012) Science , vol.338 , pp. 956-959
    • Wang, R.C.1    Wei, Y.2    An, Z.3    Zou, Z.4    Xiao, G.5    Bhagat, G.6    White, M.7    Reichelt, J.8    Levine, B.9
  • 34
    • 43649096714 scopus 로고    scopus 로고
    • Mouse 4T1 breast tumor model
    • (Coligan, J. E., Bierer, B. E., Margulies, D. H., Shevach, E. M., and Strober, W., eds), John Wiley & Sons, Inc., New York
    • Pulaski, B. A., and Ostrand-Rosenberg, S. (2001) Mouse 4T1 breast tumor model. in Current Protocols in Immunology (Coligan, J. E., Bierer, B. E., Margulies, D. H., Shevach, E. M., and Strober, W., eds), John Wiley & Sons, Inc., New York
    • (2001) Current Protocols in Immunology
    • Pulaski, B.A.1    Ostrand-Rosenberg, S.2
  • 36
    • 77954595054 scopus 로고    scopus 로고
    • Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage
    • Han, J., Goldstein, L. A., Hou, W., Froelich, C. J., Watkins, S. C., and Rabinowich, H. (2010) Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage. J. Biol. Chem. 285, 22461-22472
    • (2010) J. Biol. Chem. , vol.285 , pp. 22461-22472
    • Han, J.1    Goldstein, L.A.2    Hou, W.3    Froelich, C.J.4    Watkins, S.C.5    Rabinowich, H.6
  • 37
    • 77954617326 scopus 로고    scopus 로고
    • Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim
    • Han, J., Goldstein, L. A., Hou, W., Gastman, B. R., and Rabinowich, H. (2010) Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim. J. Biol. Chem. 285, 22473-22483
    • (2010) J. Biol. Chem. , vol.285 , pp. 22473-22483
    • Han, J.1    Goldstein, L.A.2    Hou, W.3    Gastman, B.R.4    Rabinowich, H.5
  • 38
    • 34447515353 scopus 로고    scopus 로고
    • Functional linkage between NOXA and Bim in mitochondrial apoptotic events
    • DOI 10.1074/jbc.M611186200
    • Han, J., Goldstein, L. A., Hou, W., and Rabinowich, H. (2007) Functional linkage between NOXA and Bim in mitochondrial apoptotic events. J. Biol. Chem. 282, 16223-16231 (Pubitemid 47100385)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16223-16231
    • Han, J.1    Goldstein, L.A.2    Hou, W.3    Rabinowich, H.4
  • 40
    • 77951237303 scopus 로고    scopus 로고
    • The Beclin 1 interactome
    • He, C., and Levine, B. (2010) The Beclin 1 interactome. Curr. Opin. Cell Biol. 22, 140-149
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 140-149
    • He, C.1    Levine, B.2
  • 43
    • 57749100267 scopus 로고    scopus 로고
    • MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages
    • Shi, C. S., and Kehrl, J. H. (2008) MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J. Biol. Chem. 283, 33175-33182
    • (2008) J. Biol. Chem. , vol.283 , pp. 33175-33182
    • Shi, C.S.1    Kehrl, J.H.2
  • 45
    • 0037194894 scopus 로고    scopus 로고
    • A novel protein complex linking the δ2 glutamate receptor and autophagy: Implications for neurodegeneration in lurcher mice
    • Yue, Z., Horton, A., Bravin, M., DeJager, P. L., Selimi, F., and Heintz, N. (2002) A novel protein complex linking the δ2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron 35, 921-933
    • (2002) Neuron , vol.35 , pp. 921-933
    • Yue, Z.1    Horton, A.2    Bravin, M.3    DeJager, P.L.4    Selimi, F.5    Heintz, N.6
  • 46
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • Liang, X. H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H., and Levine, B. (1999) Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402, 672-676 (Pubitemid 129516338)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 48
    • 77951750296 scopus 로고    scopus 로고
    • Selective autophagy in cancer development and therapy
    • Dikic, I., Johansen, T., and Kirkin, V. (2010) Selective autophagy in cancer development and therapy. Cancer Res. 70, 3431-3434
    • (2010) Cancer Res. , vol.70 , pp. 3431-3434
    • Dikic, I.1    Johansen, T.2    Kirkin, V.3
  • 49
    • 79551634458 scopus 로고    scopus 로고
    • Autophagy in tumorigenesis and energy metabolism: Friend by day, foe by night
    • Mathew, R., and White, E. (2011) Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night. Curr. Opin. Genet. Dev. 21, 113-119
    • (2011) Curr. Opin. Genet. Dev. , vol.21 , pp. 113-119
    • Mathew, R.1    White, E.2
  • 50
    • 78049271501 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG, and BIF-1 regulates cytokinesis and degradative endocytic traffic
    • Thoresen, S. B., Pedersen, N. M., Liestøl, K., and Stenmark, H. (2010) A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG, and BIF-1 regulates cytokinesis and degradative endocytic traffic. Exp. Cell Res. 316, 3368-3378
    • (2010) Exp. Cell Res. , vol.316 , pp. 3368-3378
    • Thoresen, S.B.1    Pedersen, N.M.2    Liestøl, K.3    Stenmark, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.