Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation

Cell Metabolism

Volumn 24, Issue 1, 2016, Pages 104-117

  Ron Harel, Noga ^a   Santos, Daniel ^a,b   Ghergurovich, Jonathan M ^c   Sage, Peter T ^a,d   Reddy, Anita ^a   Lovitch, Scott B ^a,d   Dephoure, Noah ^a   Satterstrom, F Kyle ^a   Sheffer, Michal ^a   Spinelli, Jessica B ^a   Gygi, Steven ^a   Rabinowitz, Joshua D ^c   Sharpe, Arlene H ^a,d   Haigis, Marcia C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c PRINCETON UNIVERSITY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GLUCOSE; GLUTAMINE; LACTIC ACID; PROTEOME; PURINE; SERINE; CARBON; EPITOPE; PYRIMIDINE; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; CARBON METABOLISM; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CITRIC ACID CYCLE; FATTY ACID OXIDATION; GLYCOLYSIS; IN VITRO STUDY; IN VIVO STUDY; LIPOGENESIS; METABOLIC ACTIVATION; MITOCHONDRIAL BIOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE METABOLISM; OXIDATIVE PHOSPHORYLATION; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; PROTEOMICS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CD4+ T LYMPHOCYTE; ENERGY METABOLISM; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MITOCHONDRION; ORGANELLE BIOGENESIS;

ANIMALS; CARBON; CD4-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; ENERGY METABOLISM; EPITOPES; LYMPHOCYTE ACTIVATION; METABOLIC NETWORKS AND PATHWAYS; MICE, INBRED C57BL; MITOCHONDRIA; ORGANELLE BIOGENESIS; PROTEOME; PROTEOMICS; PYRIMIDINES; T-LYMPHOCYTES;

EID: 84992389978     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.06.007     Document Type: Article

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