Fire usage and ancient hominin detoxification genes: Protective ancestral variants dominate while additional derived risk variants appear in modern humans

PLoS ONE

Volumn 11, Issue 9, 2016, Pages

  Aarts, Jac M M J G ^a,b   Alink, Gerrit M ^a,b   Scherjon, Fulco ^a   MacDonald, Katharine ^a   Smith, Alison C ^a   Nijveen, Harm ^b   Roebroeks, Wil ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; GLUTATHIONE TRANSFERASE P1; TOXIC SUBSTANCE;

AHR1 GENE; ALLELE; ARTICLE; CHIMPANZEE; CONTROLLED STUDY; CYP1A1 GENE; CYP1B1 GENE; DENISOVAN; DETOXIFICATION; DNA POLYMORPHISM; EVOLUTIONARY ADAPTATION; EXPOSURE; FIRE; FIRE USAGE; FOSSIL HOMININ; GENE; GENE DELETION; GENE LOCATION; GENE LOCUS; GENE SEQUENCE; GENETIC RISK; GENETIC SCREENING; GENETIC STABILITY; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; GORILLA; GSTP1 GENE; HOLOCENE; HOMO NEANDERTHALENSIS; HOMOZYGOSITY; HUMAN; NONHUMAN; PALEOLITHIC; PHYSICAL RESISTANCE; PRIMATE; REPRODUCTIVE FITNESS; SMOKING; TOBACCO;

EID: 84992175097     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0161102     Document Type: Article

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