Estimating the mutation load in human genomes

Nature Reviews Genetics

Volumn 16, Issue 6, 2015, Pages 333-343

  Henn, Brenna M ^a   Botigué, Laura R ^a   Bustamante, Carlos D ^b   Clark, Andrew G ^c   Gravel, Simon ^d  

^a STONY BROOK UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

BOTTLENECK POPULATION; DEMOGRAPHY; DOMINANT GENE; FOUNDER EFFECT; GENETIC LOAD; GENETIC VARIABILITY; HUMAN; HUMAN GENOME; MUTATION; NEUTRAL GENE THEORY; POPULATION GROWTH; PRIORITY JOURNAL; REVIEW; SIMULATION; BIOLOGICAL MODEL; GENE FREQUENCY; GENETIC DRIFT; GENETIC SELECTION; MIGRATION;

FOUNDER EFFECT; GENE FREQUENCY; GENES, DOMINANT; GENETIC DRIFT; GENOME, HUMAN; HUMAN MIGRATION; HUMANS; MODELS, GENETIC; MUTATION; SELECTION, GENETIC;

EID: 84929509878     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg3931     Document Type: Review

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