Jumping the gun: Smoking constituent BaP causes premature primordial follicle activation and impairs oocyte fusibility through oxidative stress

Toxicology and Applied Pharmacology

Volumn 260, Issue 1, 2012, Pages 70-80

  Sobinoff, A P ^a   Pye, V ^a   Nixon, B ^a,b   Roman, S D ^a,b   McLaughlin, E A ^a,b  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Atresia; Benzo(a)pyrene; Impaired fertilisation; Ovary; Oxidative stress; Primordial follicle

Indexed keywords

BENZO[A]PYRENE; CIGARETTE SMOKE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTOME;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL DEATH; CIGARETTE SMOKING; DOWN REGULATION; EXPOSURE; FEMALE; FEMALE INFERTILITY; FERTILIZATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MICROARRAY ANALYSIS; MITOCHONDRION; MOUSE; NEWBORN PERIOD; NONHUMAN; OOCYTE; OVARY; OVARY FOLLICLE; OVARY FOLLICLE ATRESIA; OVARY FOLLICLE DEVELOPMENT; OVARY FOLLICLE MATURATION; OXIDATIVE STRESS; REPRODUCTIVE TOXICITY; SMOKING; SPERM; SUBFERTILITY; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; BENZO(A)PYRENE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLICULAR ATRESIA; INFERTILITY, FEMALE; LIPID PEROXIDATION; MALE; MICE; MICROARRAY ANALYSIS; MITOCHONDRIA; OOCYTES; OVARIAN FOLLICLE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SMOKE; SPERM-OVUM INTERACTIONS;

MUS;

EID: 84858285162     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.01.028     Document Type: Article

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