Exposure of human skin to benzo[a]pyrene: Role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation

Toxicology

Volumn 271, Issue 3, 2010, Pages 83-86

  Costa, C ^a   Catania, S ^a   De Pasquale, R ^b   Stancanelli, R ^b   Scribano, G M ^b   Melchini, A ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

Aryl hydrocarbon receptor; Benzo a pyrene; Cytochrome P450 1A1; Oxidative stress; Polycyclic aromatic hydrocarbons; Skin

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CARBONYL DERIVATIVE; CYTOCHROME P450 1A1; REACTIVE OXYGEN METABOLITE; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN TISSUE; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PEROXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PEROXIDATION; SIMULATION; SKIN; TISSUE; TISSUE VIABILITY; WESTERN BLOTTING; DRUG EFFECT; GENE; GENETICS; LIPID PEROXIDATION; METABOLISM;

MURINAE;

BENZO(A)PYRENE; BLOTTING, WESTERN; CYTOCHROME P-450 CYP1A1; GENES; HUMANS; LIPID PEROXIDATION; OXIDATIVE STRESS; POLYCYCLIC HYDROCARBONS, AROMATIC; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; SKIN;

EID: 77952494047     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.02.014     Document Type: Article

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