Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats

British Journal of Nutrition

Volumn 110, Issue 12, 2013, Pages 2156-2164

  Li, Da ^a,b   Tian, Yan Jie ^a   Guo, Jing ^a   Sun, Wu Ping ^a   Lun, Yong Zhi ^a   Guo, Ming ^a   Luo, Ning ^a   Cao, Yu ^b   Cao, Ji Min ^c   Gong, Xiao Jie ^a   Zhou, Shi Sheng ^a  

^a DALIAN UNIVERSITY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

DNA methylation; Epigenetic changes; Nicotinamide; Obesity

Indexed keywords

1 METHYLNICOTINAMIDE; 8 HYDROXYDEOXYGUANOSINE; BETAINE; CATALASE; CHOLINE; CYSTATHIONINE BETA SYNTHASE; DNA; DNA METHYLTRANSFERASE 1; HOMOCYSTEINE; METHIONINE SYNTHASE; NICOTINAMIDE; NICOTINAMIDE METHYLTRANSFERASE; PROTEIN P53; URACIL;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA DAMAGE; DNA METHYLATION; DOSE RESPONSE; EPIGENETICS; GENE EXPRESSION; HOMOCYSTEINE METABOLISM; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIVER; LOW DRUG DOSE; MALE; METABOLIC DISORDER; NONHUMAN; PROMOTER REGION; RAT; TISSUE INJURY; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; WEIGHT GAIN;

ANIMALS; BETAINE; CHOLINE; CPG ISLANDS; DIETARY SUPPLEMENTS; DNA; DNA DAMAGE; DNA METHYLATION; EPIGENESIS, GENETIC; GLUCOSE INTOLERANCE; HOMOCYSTEINE; INSULIN RESISTANCE; LIVER; MALE; METABOLIC DISEASES; NIACIN; NIACINAMIDE; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; URACIL; VITAMIN B COMPLEX; WEIGHT GAIN;

EID: 84889249924     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114513001815     Document Type: Article

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