-
1
-
-
84877330702
-
Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy
-
Vesely MD, Schreiber RD. Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy. Ann N Y Acad Sci 2013; 1284:1–5.
-
(2013)
Ann N Y Acad Sci
, vol.1284
, pp. 1-5
-
-
Vesely, M.D.1
Schreiber, R.D.2
-
2
-
-
84883157468
-
MHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cells
-
Leone P, Shin EC, Perosa F, Vacca A, Dammacco F, Racanelli V. MHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cells. J Natl Cancer Inst 2013; 105:1172–87.
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 1172-1187
-
-
Leone, P.1
Shin, E.C.2
Perosa, F.3
Vacca, A.4
Dammacco, F.5
Racanelli, V.6
-
3
-
-
84892948376
-
Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
-
Ward MJ, Thirdborough SM, Mellows T, Riley C, Harris S, Suchak K, et al. Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer. Br J Cancer 2014; 110:489–500.
-
(2014)
Br J Cancer
, vol.110
, pp. 489-500
-
-
Ward, M.J.1
Thirdborough, S.M.2
Mellows, T.3
Riley, C.4
Harris, S.5
Suchak, K.6
-
4
-
-
2442432652
-
Comparison of surface HLA class I levels in squamous cell carcinoma cell lines of the head and neck
-
Mandic R, Lieder A, Sadowski M, Peldszus R, Werner JA. Comparison of surface HLA class I levels in squamous cell carcinoma cell lines of the head and neck. Anticancer Res 2004; 24:973–9.
-
(2004)
Anticancer Res
, vol.24
, pp. 973-979
-
-
Mandic, R.1
Lieder, A.2
Sadowski, M.3
Peldszus, R.4
Werner, J.A.5
-
5
-
-
17644413210
-
Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: association with clinical outcome
-
Meissner M, Reichert TE, Kunkel M, Gooding W, Whiteside TL, Ferrone S, et al. Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: association with clinical outcome. Clin Cancer Res 2005; 11:2552–60.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2552-2560
-
-
Meissner, M.1
Reichert, T.E.2
Kunkel, M.3
Gooding, W.4
Whiteside, T.L.5
Ferrone, S.6
-
6
-
-
33749504503
-
HLA class I antigen down-regulation in primary laryngeal squamous cell carcinoma lesions as a poor prognostic marker
-
Ogino T, Shigyo H, Ishii H, Katayama A, Miyokawa N, Harabuchi Y, et al. HLA class I antigen down-regulation in primary laryngeal squamous cell carcinoma lesions as a poor prognostic marker. Cancer Res 2006; 66:9281–9.
-
(2006)
Cancer Res
, vol.66
, pp. 9281-9289
-
-
Ogino, T.1
Shigyo, H.2
Ishii, H.3
Katayama, A.4
Miyokawa, N.5
Harabuchi, Y.6
-
7
-
-
36349025846
-
Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma
-
Mehta AM, Jordanova ES, Kenter GG, Ferrone S, Fleuren GJ. Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma. Cancer Immunol Immunother 2008; 57:197–206.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 197-206
-
-
Mehta, A.M.1
Jordanova, E.S.2
Kenter, G.G.3
Ferrone, S.4
Fleuren, G.J.5
-
8
-
-
80054707226
-
Clinical implication of HLA class I expression in breast cancer
-
Kaneko K, Ishigami S, Kijima Y, Funasako Y, Hirata M, Okumura H, et al. Clinical implication of HLA class I expression in breast cancer. BMC Cancer 2011; 11:454.
-
(2011)
BMC Cancer
, vol.11
, pp. 454
-
-
Kaneko, K.1
Ishigami, S.2
Kijima, Y.3
Funasako, Y.4
Hirata, M.5
Okumura, H.6
-
9
-
-
34250777115
-
Human leukocyte antigen class I antigen expression is an independent prognostic factor in ovarian cancer
-
Rolland P, Deen S, Scott I, Durrant L, Spendlove I. Human leukocyte antigen class I antigen expression is an independent prognostic factor in ovarian cancer. Clin Cancer Res 2007; 13:3591–6.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3591-3596
-
-
Rolland, P.1
Deen, S.2
Scott, I.3
Durrant, L.4
Spendlove, I.5
-
10
-
-
0038193533
-
Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors
-
Cabrera CM, Jimenez P, Cabrera T, Esparza C, Ruiz-Cabello F, Garrido F. Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors. Tissue Antigens 2003; 61:211–9.
-
(2003)
Tissue Antigens
, vol.61
, pp. 211-219
-
-
Cabrera, C.M.1
Jimenez, P.2
Cabrera, T.3
Esparza, C.4
Ruiz-Cabello, F.5
Garrido, F.6
-
11
-
-
84918529757
-
MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro
-
Angell TE, Lechner MG, Jang JK, LoPresti JS, Epstein AL. MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro. Clin Cancer Res 2014; 20:6034–44.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 6034-6044
-
-
Angell, T.E.1
Lechner, M.G.2
Jang, J.K.3
LoPresti, J.S.4
Epstein, A.L.5
-
12
-
-
0347759811
-
Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma?
-
Atkins D, Ferrone S, Schmahl GE, Storkel S, Seliger B. Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma? J Urol 2004; 171(Pt 1):885–9.
-
(2004)
J Urol
, vol.171
, pp. 885-889
-
-
Atkins, D.1
Ferrone, S.2
Schmahl, G.E.3
Storkel, S.4
Seliger, B.5
-
13
-
-
0033945925
-
Functional deficiencies of components of the MHC class I antigen pathway in human tumors of epithelial origin
-
Delp K, Momburg F, Hilmes C, Huber C, Seliger B. Functional deficiencies of components of the MHC class I antigen pathway in human tumors of epithelial origin. Bone Marrow Transplant 2000; 25(Suppl 2):S88–95.
-
(2000)
Bone Marrow Transplant
, vol.25
, pp. S88-95
-
-
Delp, K.1
Momburg, F.2
Hilmes, C.3
Huber, C.4
Seliger, B.5
-
14
-
-
0030818665
-
Expression and function of the peptide transporters in escape variants of human renal cell carcinomas
-
Seliger B, Hohne A, Jung D, Kallfelz M, Knuth A, Jaeger E, et al. Expression and function of the peptide transporters in escape variants of human renal cell carcinomas. Exp Hematol 1997; 25:608–14.
-
(1997)
Exp Hematol
, vol.25
, pp. 608-614
-
-
Seliger, B.1
Hohne, A.2
Jung, D.3
Kallfelz, M.4
Knuth, A.5
Jaeger, E.6
-
15
-
-
0035893563
-
Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway
-
Seliger B, Ritz U, Abele R, Bock M, Tampe R, Sutter G, et al. Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway. Cancer Res 2001; 61:8647–50.
-
(2001)
Cancer Res
, vol.61
, pp. 8647-8650
-
-
Seliger, B.1
Ritz, U.2
Abele, R.3
Bock, M.4
Tampe, R.5
Sutter, G.6
-
16
-
-
77449133036
-
Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer
-
Seliger B, Stoehr R, Handke D, Mueller A, Ferrone S, Wullich B, et al. Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer. Cancer Immunol Immunother 2010; 59:529–40.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 529-540
-
-
Seliger, B.1
Stoehr, R.2
Handke, D.3
Mueller, A.4
Ferrone, S.5
Wullich, B.6
-
17
-
-
84866375600
-
Post-transcriptional and epigenetic regulation of antigen processing machinery (APM) components and HLA-I in cervical cancers from Uighur women
-
Hasim A, Abudula M, Aimiduo R, Ma JQ, Jiao Z, Akula G, et al. Post-transcriptional and epigenetic regulation of antigen processing machinery (APM) components and HLA-I in cervical cancers from Uighur women. PLoS One 2012; 7:e44952.
-
(2012)
PLoS One
, vol.7
-
-
Hasim, A.1
Abudula, M.2
Aimiduo, R.3
Ma, J.Q.4
Jiao, Z.5
Akula, G.6
-
18
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, Chau V, et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995; 269:682–5.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
Beer-Romero, P.4
Del Sal, G.5
Chau, V.6
-
19
-
-
34250011799
-
The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases
-
Wang J, Maldonado MA. The ubiquitin-proteasome system and its role in inflammatory and autoimmune diseases. Cell Mol Immunol 2006; 3:255–61.
-
(2006)
Cell Mol Immunol
, vol.3
, pp. 255-261
-
-
Wang, J.1
Maldonado, M.A.2
-
20
-
-
0036777957
-
The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides
-
Goldberg AL, Cascio P, Saric T, Rock KL. The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol Immunol 2002; 39:147–64.
-
(2002)
Mol Immunol
, vol.39
, pp. 147-164
-
-
Goldberg, A.L.1
Cascio, P.2
Saric, T.3
Rock, K.L.4
-
21
-
-
0026070217
-
Second proteasome-related gene in the human MHC class II region
-
Kelly A, Powis SH, Glynne R, Radley E, Beck S, Trowsdale J. Second proteasome-related gene in the human MHC class II region. Nature 1991; 353:667–8.
-
(1991)
Nature
, vol.353
, pp. 667-668
-
-
Kelly, A.1
Powis, S.H.2
Glynne, R.3
Radley, E.4
Beck, S.5
Trowsdale, J.6
-
22
-
-
0025771623
-
A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC
-
Glynne R, Powis SH, Beck S, Kelly A, Kerr LA, Trowsdale J. A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC. Nature 1991; 353:357–60.
-
(1991)
Nature
, vol.353
, pp. 357-360
-
-
Glynne, R.1
Powis, S.H.2
Beck, S.3
Kelly, A.4
Kerr, L.A.5
Trowsdale, J.6
-
23
-
-
0025998206
-
Subunit of the ‘20S’ proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex
-
Ortiz-Navarrete V, Seelig A, Gernold M, Frentzel S, Kloetzel PM, Hammerling GJ. Subunit of the ‘20S’ proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex. Nature 1991; 353:662–4.
-
(1991)
Nature
, vol.353
, pp. 662-664
-
-
Ortiz-Navarrete, V.1
Seelig, A.2
Gernold, M.3
Frentzel, S.4
Kloetzel, P.M.5
Hammerling, G.J.6
-
24
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 1994; 78:761–71.
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
-
25
-
-
0034659804
-
The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses
-
Schwarz K, de Giuli R, Schmidtke G, Kostka S, van den Broek M, Kim KB, et al. The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses. J Immunol 2000; 164:6147–57.
-
(2000)
J Immunol
, vol.164
, pp. 6147-6157
-
-
Schwarz, K.1
de Giuli, R.2
Schmidtke, G.3
Kostka, S.4
van den Broek, M.5
Kim, K.B.6
-
26
-
-
84962540914
-
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
-
Tripathi SC, Peters HL, Taguchi A, Katayama H, Wang H, Momin A, et al. Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome. Proc Natl Acad Sci U S A 2016; 113:E1555–64.
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E1555-E1564
-
-
Tripathi, S.C.1
Peters, H.L.2
Taguchi, A.3
Katayama, H.4
Wang, H.5
Momin, A.6
-
27
-
-
34247529384
-
Genetic variation of antigen processing machinery components and association with cervical carcinoma
-
Mehta AM, Jordanova ES, van Wezel T, Uh HW, Corver WE, Kwappenberg KM, et al. Genetic variation of antigen processing machinery components and association with cervical carcinoma. Genes Chromosom Cancer 2007; 46:577–86.
-
(2007)
Genes Chromosom Cancer
, vol.46
, pp. 577-586
-
-
Mehta, A.M.1
Jordanova, E.S.2
van Wezel, T.3
Uh, H.W.4
Corver, W.E.5
Kwappenberg, K.M.6
-
28
-
-
84863002934
-
A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice
-
Wehenkel M, Ban JO, Ho YK, Carmony KC, Hong JT, Kim KB. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice. Br J Cancer 2012; 107:53–62.
-
(2012)
Br J Cancer
, vol.107
, pp. 53-62
-
-
Wehenkel, M.1
Ban, J.O.2
Ho, Y.K.3
Carmony, K.C.4
Hong, J.T.5
Kim, K.B.6
-
30
-
-
0036902105
-
An IFN-γ-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
-
Saric T, Chang SC, Hattori A, York IA, Markant S, Rock KL, et al. An IFN-γ-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol 2002; 3:1169–76.
-
(2002)
Nat Immunol
, vol.3
, pp. 1169-1176
-
-
Saric, T.1
Chang, S.C.2
Hattori, A.3
York, I.A.4
Markant, S.5
Rock, K.L.6
-
31
-
-
33745125912
-
Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance
-
York IA, Brehm MA, Zendzian S, Towne CF, Rock KL. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A 2006; 103:9202–7.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9202-9207
-
-
York, I.A.1
Brehm, M.A.2
Zendzian, S.3
Towne, C.F.4
Rock, K.L.5
-
32
-
-
0036884090
-
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8–9 residues
-
York IA, Chang SC, Saric T, Keys JA, Favreau JM, Goldberg AL, et al. The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8–9 residues. Nat Immunol 2002; 3:1177–84.
-
(2002)
Nat Immunol
, vol.3
, pp. 1177-1184
-
-
York, I.A.1
Chang, S.C.2
Saric, T.3
Keys, J.A.4
Favreau, J.M.5
Goldberg, A.L.6
-
33
-
-
29244461714
-
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
-
Hammer GE, Gonzalez F, Champsaur M, Cado D, Shastri N. The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nat Immunol 2006; 7:103–12.
-
(2006)
Nat Immunol
, vol.7
, pp. 103-112
-
-
Hammer, G.E.1
Gonzalez, F.2
Champsaur, M.3
Cado, D.4
Shastri, N.5
-
34
-
-
33846988640
-
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides
-
Hammer GE, Gonzalez F, James E, Nolla H, Shastri N. In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat Immunol 2007; 8:101–8.
-
(2007)
Nat Immunol
, vol.8
, pp. 101-108
-
-
Hammer, G.E.1
Gonzalez, F.2
James, E.3
Nolla, H.4
Shastri, N.5
-
35
-
-
84916890237
-
Functionally distinct ERAP1 allotype combinations distinguish individuals with ankylosing spondylitis
-
Reeves E, Colebatch-Bourn A, Elliott T, Edwards CJ, James E. Functionally distinct ERAP1 allotype combinations distinguish individuals with ankylosing spondylitis. Proc Natl Acad Sci U S A 2014; 111:17594–9.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 17594-17599
-
-
Reeves, E.1
Colebatch-Bourn, A.2
Elliott, T.3
Edwards, C.J.4
James, E.5
-
36
-
-
77953229217
-
Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma
-
Kamphausen E, Kellert C, Abbas T, Akkad N, Tenzer S, Pawelec G, et al. Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma. Cancer Immunol Immunother 2010; 59:1273–84.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1273-1284
-
-
Kamphausen, E.1
Kellert, C.2
Abbas, T.3
Akkad, N.4
Tenzer, S.5
Pawelec, G.6
-
37
-
-
84999921332
-
The role of endoplasmic reticulum aminopeptidase 1 biology in immune evasion by tumours
-
Reeves EJE. The role of endoplasmic reticulum aminopeptidase 1 biology in immune evasion by tumours. J Vaccines Immunol 2015; 1:28–35.
-
(2015)
J Vaccines Immunol
, vol.1
, pp. 28-35
-
-
Reeves, E.J.E.1
-
38
-
-
84878035647
-
Induction of protective antitumor immunity through attenuation of ERAAP function
-
James E, Bailey I, Sugiyarto G, Elliott T. Induction of protective antitumor immunity through attenuation of ERAAP function. J Immunol 2013; 190:5839–46.
-
(2013)
J Immunol
, vol.190
, pp. 5839-5846
-
-
James, E.1
Bailey, I.2
Sugiyarto, G.3
Elliott, T.4
-
39
-
-
48749106928
-
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues
-
Fruci D, Giacomini P, Nicotra MR, Forloni M, Fraioli R, Saveanu L, et al. Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues. J Cell Physiol 2008; 216:742–9.
-
(2008)
J Cell Physiol
, vol.216
, pp. 742-749
-
-
Fruci, D.1
Giacomini, P.2
Nicotra, M.R.3
Forloni, M.4
Fraioli, R.5
Saveanu, L.6
-
40
-
-
65349123542
-
Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma
-
Mehta AM, Jordanova ES, Corver WE, van Wezel T, Uh HW, Kenter GG, et al. Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma. Genes Chromosom Cancer 2009; 48:410–8.
-
(2009)
Genes Chromosom Cancer
, vol.48
, pp. 410-418
-
-
Mehta, A.M.1
Jordanova, E.S.2
Corver, W.E.3
van Wezel, T.4
Uh, H.W.5
Kenter, G.G.6
-
41
-
-
84939976181
-
Differences in genetic variation in antigen-processing machinery components and association with cervical carcinoma risk in two Indonesian populations
-
Mehta AM, Spaans VM, Mahendra NB, Osse EM, Vet JN, Purwoto G, et al. Differences in genetic variation in antigen-processing machinery components and association with cervical carcinoma risk in two Indonesian populations. Immunogenetics 2015; 67:267–75.
-
(2015)
Immunogenetics
, vol.67
, pp. 267-275
-
-
Mehta, A.M.1
Spaans, V.M.2
Mahendra, N.B.3
Osse, E.M.4
Vet, J.N.5
Purwoto, G.6
-
42
-
-
84879663069
-
Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity
-
Reeves E, Edwards CJ, Elliott T, James E. Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity. J Immunol 2013; 191:35–43.
-
(2013)
J Immunol
, vol.191
, pp. 35-43
-
-
Reeves, E.1
Edwards, C.J.2
Elliott, T.3
James, E.4
-
43
-
-
84889671845
-
Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses
-
Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, Kokkala P, et al. Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proc Natl Acad Sci U S A 2013; 110:19890–5.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 19890-19895
-
-
Zervoudi, E.1
Saridakis, E.2
Birtley, J.R.3
Seregin, S.S.4
Reeves, E.5
Kokkala, P.6
-
44
-
-
0027239749
-
Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter
-
Neefjes JJ, Momburg F, Hammerling GJ. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science 1993; 261:769–71.
-
(1993)
Science
, vol.261
, pp. 769-771
-
-
Neefjes, J.J.1
Momburg, F.2
Hammerling, G.J.3
-
45
-
-
0028012028
-
Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas
-
Cromme FV, Airey J, Heemels MT, Ploegh HL, Keating PJ, Stern PL, et al. Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas. J Exp Med 1994; 179:335–40.
-
(1994)
J Exp Med
, vol.179
, pp. 335-340
-
-
Cromme, F.V.1
Airey, J.2
Heemels, M.T.3
Ploegh, H.L.4
Keating, P.J.5
Stern, P.L.6
-
46
-
-
84862122547
-
The role of classical and non-classical HLA class I antigens in human tumors
-
Bukur J, Jasinski S, Seliger B. The role of classical and non-classical HLA class I antigens in human tumors. Semin Cancer Biol 2012; 22:350–8.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 350-358
-
-
Bukur, J.1
Jasinski, S.2
Seliger, B.3
-
47
-
-
0028094647
-
Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer
-
Kaklamanis L, Townsend A, Doussis-Anagnostopoulou IA, Mortensen N, Harris AL, Gatter KC. Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer. Am J Pathol 1994; 145:505–9.
-
(1994)
Am J Pathol
, vol.145
, pp. 505-509
-
-
Kaklamanis, L.1
Townsend, A.2
Doussis-Anagnostopoulou, I.A.3
Mortensen, N.4
Harris, A.L.5
Gatter, K.C.6
-
48
-
-
0028606109
-
Characteristics of peptide and major histocompatibility complex class I/β2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2)
-
Androlewicz MJ, Ortmann B, van Endert PM, Spies T, Cresswell P. Characteristics of peptide and major histocompatibility complex class I/β2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2). Proc Natl Acad Sci U S A 1994; 91:12716–20.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12716-12720
-
-
Androlewicz, M.J.1
Ortmann, B.2
van Endert, P.M.3
Spies, T.4
Cresswell, P.5
-
49
-
-
0026593016
-
Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex
-
Kelly A, Powis SH, Kerr LA, Mockridge I, Elliott T, Bastin J, et al. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 1992; 355:641–4.
-
(1992)
Nature
, vol.355
, pp. 641-644
-
-
Kelly, A.1
Powis, S.H.2
Kerr, L.A.3
Mockridge, I.4
Elliott, T.5
Bastin, J.6
-
50
-
-
84928349244
-
Functional roles of calreticulin in cancer biology
-
Lu YC, Weng WC, Lee H. Functional roles of calreticulin in cancer biology. Biomed Res Int 2015; 2015:526524.
-
(2015)
Biomed Res Int
, vol.2015
, pp. 526524
-
-
Lu, Y.C.1
Weng, W.C.2
Lee, H.3
-
51
-
-
33846530584
-
Regulation of calnexin sub-cellular localization modulates endoplasmic reticulum stress-induced apoptosis in MCF-7 cells
-
Delom F, Fessart D, Chevet E. Regulation of calnexin sub-cellular localization modulates endoplasmic reticulum stress-induced apoptosis in MCF-7 cells. Apoptosis 2007; 12:293–305.
-
(2007)
Apoptosis
, vol.12
, pp. 293-305
-
-
Delom, F.1
Fessart, D.2
Chevet, E.3
-
52
-
-
84896724517
-
Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing
-
Gameiro SR, Jammeh ML, Wattenberg MM, Tsang KY, Ferrone S, Hodge JW. Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing. Oncotarget 2014; 5:403–16.
-
(2014)
Oncotarget
, vol.5
, pp. 403-416
-
-
Gameiro, S.R.1
Jammeh, M.L.2
Wattenberg, M.M.3
Tsang, K.Y.4
Ferrone, S.5
Hodge, J.W.6
-
53
-
-
84977178366
-
Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer
-
Ryan D, Carberry S, Murphy AC, Lindner AU, Fay J, Hector S, et al. Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer. J Transl Med 2016; 14:196.
-
(2016)
J Transl Med
, vol.14
, pp. 196
-
-
Ryan, D.1
Carberry, S.2
Murphy, A.C.3
Lindner, A.U.4
Fay, J.5
Hector, S.6
-
54
-
-
84955460301
-
Calnexin is a novel sero-diagnostic marker for lung cancer
-
Kobayashi M, Nagashio R, Jiang SX, Saito K, Tsuchiya B, Ryuge S, et al. Calnexin is a novel sero-diagnostic marker for lung cancer. Lung Cancer 2015; 90:342–5.
-
(2015)
Lung Cancer
, vol.90
, pp. 342-345
-
-
Kobayashi, M.1
Nagashio, R.2
Jiang, S.X.3
Saito, K.4
Tsuchiya, B.5
Ryuge, S.6
-
55
-
-
84888871962
-
Downregulation of ERp57 expression is associated with poor prognosis in early-stage cervical cancer
-
Chung H, Cho H, Perry C, Song J, Ylaya K, Lee H, et al. Downregulation of ERp57 expression is associated with poor prognosis in early-stage cervical cancer. Biomarkers 2013; 18:573–9.
-
(2013)
Biomarkers
, vol.18
, pp. 573-579
-
-
Chung, H.1
Cho, H.2
Perry, C.3
Song, J.4
Ylaya, K.5
Lee, H.6
-
56
-
-
33845494066
-
Expression and prognostic significance of prothymosin-α and ERp57 in human gastric cancer
-
Leys CM, Nomura S, LaFleur BJ, Ferrone S, Kaminishi M, Montgomery E, et al. Expression and prognostic significance of prothymosin-α and ERp57 in human gastric cancer. Surgery 2007; 141:41–50.
-
(2007)
Surgery
, vol.141
, pp. 41-50
-
-
Leys, C.M.1
Nomura, S.2
LaFleur, B.J.3
Ferrone, S.4
Kaminishi, M.5
Montgomery, E.6
-
57
-
-
77956297939
-
The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding
-
Van Hateren A, James E, Bailey A, Phillips A, Dalchau N, Elliott T. The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding. Tissue Antigens 2010; 76:259–75.
-
(2010)
Tissue Antigens
, vol.76
, pp. 259-275
-
-
Van Hateren, A.1
James, E.2
Bailey, A.3
Phillips, A.4
Dalchau, N.5
Elliott, T.6
-
58
-
-
4143051423
-
Tapasin enhances MHC class I peptide presentation according to peptide half-life
-
Howarth M, Williams A, Tolstrup AB, Elliott T. Tapasin enhances MHC class I peptide presentation according to peptide half-life. Proc Natl Acad Sci U S A 2004; 101:11737–42.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 11737-11742
-
-
Howarth, M.1
Williams, A.2
Tolstrup, A.B.3
Elliott, T.4
-
59
-
-
0036230677
-
Optimization of the MHC class I peptide cargo is dependent on tapasin
-
Williams AP, Peh CA, Purcell AW, McCluskey J, Elliott T. Optimization of the MHC class I peptide cargo is dependent on tapasin. Immunity 2002; 16:509–20.
-
(2002)
Immunity
, vol.16
, pp. 509-520
-
-
Williams, A.P.1
Peh, C.A.2
Purcell, A.W.3
McCluskey, J.4
Elliott, T.5
-
60
-
-
0035137084
-
Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines
-
Seliger B, Schreiber K, Delp K, Meissner M, Hammers S, Reichert T, et al. Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines. Tissue Antigens 2001; 57:39–45.
-
(2001)
Tissue Antigens
, vol.57
, pp. 39-45
-
-
Seliger, B.1
Schreiber, K.2
Delp, K.3
Meissner, M.4
Hammers, S.5
Reichert, T.6
-
62
-
-
0038727560
-
Downregulation of tapasin expression in progressive human malignant melanoma
-
Dissemond J, Kothen T, Mors J, Weimann TK, Lindeke A, Goos M, et al. Downregulation of tapasin expression in progressive human malignant melanoma. Arch Dermatol Res 2003; 295:43–9.
-
(2003)
Arch Dermatol Res
, vol.295
, pp. 43-49
-
-
Dissemond, J.1
Kothen, T.2
Mors, J.3
Weimann, T.K.4
Lindeke, A.5
Goos, M.6
-
63
-
-
40949151469
-
Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival
-
Lou Y, Basha G, Seipp RP, Cai B, Chen SS, Moise AR, et al. Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival. Clin Cancer Res 2008; 14:1494–501.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1494-1501
-
-
Lou, Y.1
Basha, G.2
Seipp, R.P.3
Cai, B.4
Chen, S.S.5
Moise, A.R.6
-
64
-
-
3442879963
-
Tapasin decreases immune responsiveness to a model tumor antigen
-
Turnquist HR, Kohlgraf KG, McIlhaney MM, Mosley RL, Hollingsworth MA, Solheim JC. Tapasin decreases immune responsiveness to a model tumor antigen. J Clin Immunol 2004; 24:462–70.
-
(2004)
J Clin Immunol
, vol.24
, pp. 462-470
-
-
Turnquist, H.R.1
Kohlgraf, K.G.2
McIlhaney, M.M.3
Mosley, R.L.4
Hollingsworth, M.A.5
Solheim, J.C.6
-
65
-
-
84907087914
-
Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes
-
Vlkova V, Stepanek I, Hruskova V, Senigl F, Mayerova V, Sramek M, et al. Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes. Oncotarget 2014; 5:6923–35.
-
(2014)
Oncotarget
, vol.5
, pp. 6923-6935
-
-
Vlkova, V.1
Stepanek, I.2
Hruskova, V.3
Senigl, F.4
Mayerova, V.5
Sramek, M.6
-
66
-
-
65449171187
-
Autophagy and its role in MHC-mediated antigen presentation
-
Crotzer VL, Blum JS. Autophagy and its role in MHC-mediated antigen presentation. J Immunol 2009; 182:3335–41.
-
(2009)
J Immunol
, vol.182
, pp. 3335-3341
-
-
Crotzer, V.L.1
Blum, J.S.2
-
67
-
-
0030832073
-
Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) region
-
Stumptner P, Benaroch P. Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) region. EMBO J 1997; 16:5807–18.
-
(1997)
EMBO J
, vol.16
, pp. 5807-5818
-
-
Stumptner, P.1
Benaroch, P.2
-
68
-
-
0025249197
-
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
-
Neefjes JJ, Stollorz V, Peters PJ, Geuze HJ, Ploegh HL. The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. Cell 1990; 61:171–83.
-
(1990)
Cell
, vol.61
, pp. 171-183
-
-
Neefjes, J.J.1
Stollorz, V.2
Peters, P.J.3
Geuze, H.J.4
Ploegh, H.L.5
-
69
-
-
0033083688
-
Cathepsin S required for normal MHC class II peptide loading and germinal center development
-
Shi GP, Villadangos JA, Dranoff G, Small C, Gu L, Haley KJ, et al. Cathepsin S required for normal MHC class II peptide loading and germinal center development. Immunity 1999; 10:197–206.
-
(1999)
Immunity
, vol.10
, pp. 197-206
-
-
Shi, G.P.1
Villadangos, J.A.2
Dranoff, G.3
Small, C.4
Gu, L.5
Haley, K.J.6
-
70
-
-
0023521156
-
B-cell lymphomas of high-grade malignancy frequently lack HLA-DR, -DP and -DQ antigens and associated invariant chain
-
Momburg F, Herrmann B, Moldenhauer G, Moller P. B-cell lymphomas of high-grade malignancy frequently lack HLA-DR, -DP and -DQ antigens and associated invariant chain. Int J Cancer 1987; 40:598–603.
-
(1987)
Int J Cancer
, vol.40
, pp. 598-603
-
-
Momburg, F.1
Herrmann, B.2
Moldenhauer, G.3
Moller, P.4
-
71
-
-
0023860213
-
Differential expression of HLA-DR, HLA-DP, HLA-DQ and associated invariant chain (Ii) in normal colorectal mucosa, adenoma and carcinoma
-
Degener T, Momburg F, Moller P. Differential expression of HLA-DR, HLA-DP, HLA-DQ and associated invariant chain (Ii) in normal colorectal mucosa, adenoma and carcinoma. Virchows Arch A Pathol Anat Histopathol 1988; 412:315–22.
-
(1988)
Virchows Arch A Pathol Anat Histopathol
, vol.412
, pp. 315-322
-
-
Degener, T.1
Momburg, F.2
Moller, P.3
-
72
-
-
6344222170
-
HLA-DRB alleles are differentially expressed by tumor cells in breast carcinoma
-
Oldford SA, Robb JD, Watson PH, Drover S. HLA-DRB alleles are differentially expressed by tumor cells in breast carcinoma. Int J Cancer 2004; 112:399–406.
-
(2004)
Int J Cancer
, vol.112
, pp. 399-406
-
-
Oldford, S.A.1
Robb, J.D.2
Watson, P.H.3
Drover, S.4
-
73
-
-
33750219785
-
Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients
-
Oldford SA, Robb JD, Codner D, Gadag V, Watson PH, Drover S. Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients. Int Immunol 2006; 18:1591–602.
-
(2006)
Int Immunol
, vol.18
, pp. 1591-1602
-
-
Oldford, S.A.1
Robb, J.D.2
Codner, D.3
Gadag, V.4
Watson, P.H.5
Drover, S.6
-
74
-
-
79952816655
-
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
-
Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature 2011; 471:377–81.
-
(2011)
Nature
, vol.471
, pp. 377-381
-
-
Steidl, C.1
Shah, S.P.2
Woolcock, B.W.3
Rui, L.4
Kawahara, M.5
Farinha, P.6
-
75
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009; 137:1062–75.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
-
76
-
-
77951233373
-
Cancer associated fibroblasts (CAFs) in tumor microenvironment
-
Xing F, Saidou J, Watabe K. Cancer associated fibroblasts (CAFs) in tumor microenvironment. Front Biosci (Landmark Ed) 2010; 15:166–79.
-
(2010)
Front Biosci (Landmark Ed)
, vol.15
, pp. 166-179
-
-
Xing, F.1
Saidou, J.2
Watabe, K.3
-
77
-
-
79959745851
-
The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis
-
Gooden MJ, de Bock GH, Leffers N, Daemen T, Nijman HW. The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis. Br J Cancer 2011; 105:93–103.
-
(2011)
Br J Cancer
, vol.105
, pp. 93-103
-
-
Gooden, M.J.1
de Bock, G.H.2
Leffers, N.3
Daemen, T.4
Nijman, H.W.5
-
78
-
-
58149303099
-
Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer
-
Leffers N, Gooden MJ, de Jong RA, Hoogeboom BN, ten Hoor KA, Hollema H, et al. Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer. Cancer Immunol Immunother 2009; 58:449–59.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 449-459
-
-
Leffers, N.1
Gooden, M.J.2
de Jong, R.A.3
Hoogeboom, B.N.4
ten Hoor, K.A.5
Hollema, H.6
-
79
-
-
27144471372
-
Increased intratumor Vα24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas
-
Tachibana T, Onodera H, Tsuruyama T, Mori A, Nagayama S, Hiai H, et al. Increased intratumor Vα24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas. Clin Cancer Res 2005; 11:7322–7.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7322-7327
-
-
Tachibana, T.1
Onodera, H.2
Tsuruyama, T.3
Mori, A.4
Nagayama, S.5
Hiai, H.6
-
80
-
-
0041381374
-
What is trogocytosis and what is its purpose?
-
Joly E, Hudrisier D. What is trogocytosis and what is its purpose? Nat Immunol 2003; 4:815.
-
(2003)
Nat Immunol
, vol.4
, pp. 815
-
-
Joly, E.1
Hudrisier, D.2
-
82
-
-
84923037149
-
Human T cell crosstalk is induced by tumor membrane transfer
-
Uzana R, Eisenberg G, Merims S, Frankenburg S, Pato A, Yefenof E, et al. Human T cell crosstalk is induced by tumor membrane transfer. PLoS One 2015; 10:e0118244.
-
(2015)
PLoS One
, vol.10
-
-
Uzana, R.1
Eisenberg, G.2
Merims, S.3
Frankenburg, S.4
Pato, A.5
Yefenof, E.6
-
83
-
-
78049416842
-
MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors
-
Leisegang M, Wilde S, Spranger S, Milosevic S, Frankenberger B, Uckert W, et al. MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors. J Clin Invest 2010; 120:3869–77.
-
(2010)
J Clin Invest
, vol.120
, pp. 3869-3877
-
-
Leisegang, M.1
Wilde, S.2
Spranger, S.3
Milosevic, S.4
Frankenberger, B.5
Uckert, W.6
-
85
-
-
64849103619
-
Antigen processing and MHC-II presentation by dermal and tumor-infiltrating dendritic cells
-
Gerner MY, Mescher MF. Antigen processing and MHC-II presentation by dermal and tumor-infiltrating dendritic cells. J Immunol 2009; 182:2726–37.
-
(2009)
J Immunol
, vol.182
, pp. 2726-2737
-
-
Gerner, M.Y.1
Mescher, M.F.2
-
86
-
-
84868030361
-
Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer
-
Quatromoni JG, Eruslanov E. Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer. Am J Transl Res 2012; 4:376–89.
-
(2012)
Am J Transl Res
, vol.4
, pp. 376-389
-
-
Quatromoni, J.G.1
Eruslanov, E.2
-
87
-
-
77955038532
-
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes
-
Movahedi K, Laoui D, Gysemans C, Baeten M, Stange G, Van den Bossche J, et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res 2010; 70:5728–39.
-
(2010)
Cancer Res
, vol.70
, pp. 5728-5739
-
-
Movahedi, K.1
Laoui, D.2
Gysemans, C.3
Baeten, M.4
Stange, G.5
Van den Bossche, J.6
|