Downregulation of tapasin expression in progressive human malignant melanoma

Archives of Dermatological Research

Volumn 295, Issue 2, 2003, Pages 43-49

  Dissemond, J ^a   Kothen, T ^a   Mors J ^a   Weimann, T K ^a   Lindeke, A ^a   Goos, M ^a   Wagner, S N ^a,b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b Universitatsklinik fur Dermatologie   (Austria)

Author keywords

Melanoma; Metastases; MHC class I; Tapasin

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TAPASIN;

ADULT; AGED; ANTIGEN PRESENTATION; ARTICLE; CELLULAR IMMUNITY; ENDOPLASMIC RETICULUM; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; MAJOR CLINICAL STUDY; MALE; MELANOMA; METASTASIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; TUMOR ESCAPE; TUMOR GROWTH;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIPORTERS; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; MALE; MELANOMA; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; SKIN NEOPLASMS; STAINING AND LABELING;

EID: 0038727560     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-003-0393-8     Document Type: Article

References (26)

1. Bennett EM, Bennink JR, Yewdell JW, Brodsky FM (1999) Cutting edge: adenovirus E19 has two mechanisms for affecting class I MHC expression. J Immunol 162:5049-5052
2. Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, Macdonald S, Pulford KAF, Stein H, Mason DY (1984) Immunoenzymatic labeling of monoclonal antibodies of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complex). J Histochem Cytochem 32:219-229
3. Cresswell P, Bangia N, Dick T, Diedrich G (1999) The nature of the MHC class I peptide loading complex. Immunol Rev 172:21-28
4. Dangoria NS, DeLay ML, Kingbury DJ, Mear JP, Uchanska-Ziegler B, Ziegler A, Colbert RA (2002) HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum. J Biol Chem 277:23459-23468
5. Elliott T (1997) How does TAP associate with MHC class I molecules. Immunol Today 18:375-379
6. Ferrone S, Marincola FM (1995) Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunol Today 16:487-494
7. Garbi N, Tan P, Dsiehl AD, Chambers BJ, Ljunggren HG, Momburg F, Hämmerling GJ (2000) Impaired immune responses and altered peptide repertoire in tapasin-deficient mice. Nat Immunol 1:234-238
8. Grandea AG 3rd, Golovina TN, Hamilton SE, Sriram V, Spies T, Brutkiewicz RR, Harty JT, Eisenlohr LC, Van Kaer L (2000) Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity 13:213-222
9. Harris MR, Yu YYL, Kindle CS, Hansen TH, Solheim JC (1998) Calreticulin and calnexin interact with different protein and glycan determinants during the assembly of MHC class I. J Immunol 160:5404-5409
10. Kageshita T, Hirai S, Ono T, Hicklin DJ, Ferrone S (1999) Downregulation of HLA class I antigen-processing molecules in malignant melanoma. Am J Pathol 154:745-754
11. Momburg F, Tan P (2002) Tapasin - the keystone of loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum. Mol Immunol 39:217
12. Ortmann B, Copeman J, Lehner B, Sadasiva B, Herberg JA, Grandea AG, Riddell SR, Tampe R, Spies T, Trowsdale, Cresswell P (1997) A critical role for tapasin in the assembly and function of multimeric MHC class I complexes. Science 277:1306-1309
13. Peh CA, Burrows SR, Barnden M, Khanna R, Cresswell P, Moss DJ, McCluskey J (1998) HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading. Immunity 8:531-542
14. Purcell AW, Kelly AJ, Peh CA, Dudek NL, McCluskey J (2000) Endogenous and exogenous factors contributing to the surface expression of HLA B27 on mutant antigen presenting cells. Hum Immunol 61:120-130
15. Purcell AW, Gorman JJ, Garcia-Peydro M, Paradela A, Burrows SR, Talbo GH, Laham N, Peh CA, Reynolds EC, Lopez De Castro JA, McCluskey J (2001) Quantitative and qualitative influences of tapasin on the class I peptide repertoire. J Immunol 166:1016-1027
16. Restifo NP, Marincola FM, Kawakami Y, Taubenberger J, Yannelli JR, Rosenberg SA (1996) Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy. J Natl Cancer Inst 88:100-108
17. Ritz U, Momburg F, Pilch H, Huber C, Maeurer MJ, Seliger B (2001) Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma. Int J Oncol 19:1211-1220
18. Sadasivan B, Lehner PJ, Orthmann B, Spies T, Cresswell P (1996) Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity 5:103-114
19. Seliger B, Schreiber K, Delp K, Meissner M, Hammers S, Reichert T, Pawlischlo K, Tampe R, Huber C (2001) Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines. Tissue Antigens 57:39-45
20. Shi Y, Radvanyi LG, Sharma A, Shaw P, Green DR, Miller RR, Mills GB (1995) CD28-mediated signaling in vivo prevents activation-induced apoptosis in the thymus and alters peripheral lymphocyte homeostasis. J Immunol 1555:1829-1837
21. Solheim JC, Carreno BM, Hansen TH (1997) Are transporter associated with antigen processing (TAP) and tapasin class I MHC chaperones? J Immunol 158:541-543
22. Tan P, Kropshofer H, Mandelboim O, Bulbuc N, Hammerling GJ, Momburg F (2002) Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading. J Immunol 168:1950-1960
23. van Duinen SG, Ruiter DJ, Broecker EB, van der Velde EA, Sorg C, Welvaart K, Ferrone S (1988) Level of HLA antigens in locoregional metastases and clinical course of the disease in patients with melanoma. Cancer Res 48:1019-1025
24. van Endert PM (1999) Genes regulating MHC class I processing of antigen. Curr Opin Immunol 11:82-88
25. White CA, Thomson SA, Cooper L, van Endert PM, Tampe R, Coupar B, Qiu L, Parsons PG, Moss DJ, Khanna R (1998) Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells. Int J Cancer 75:590-595
26. Yabe T, Kawamura S, Sato M, Kashiwase K, Tanaka H, Ishikawa Y, Asao Y, Oyama J, Tsuruta K, Tadokoro K, Juji T (2002) A subject with a novel type I bare lymphocyte syndrome has tapasin deficiency due to deletion of 4 exons by Alu-mediated recombination. Blood 100:1496-1498