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Volumn 61, Issue 3, 2003, Pages 211-219

Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors

Author keywords

2 microglobulin; Colorectal tumors; HLA; LMP7; TAP2

Indexed keywords

BETA 2 MICROGLOBULIN; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; LOW MOLECULAR WEIGHT PROTEIN 2; LOW MOLECULAR WEIGHT PROTEIN 7; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MESSENGER RNA; MONOCLONAL ANTIBODY; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 2; UNCLASSIFIED DRUG;

EID: 0038193533     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0039.2003.00020.x     Document Type: Article
Times cited : (137)

References (43)
  • 1
    • 0031080901 scopus 로고    scopus 로고
    • Implications for immunosurveillance of altered HLA class I phenotypes in human tumors
    • Garrido F, Ruiz-Cabello F, Cabrera T et al. Implications for immunosurveillance of altered HLA class I phenotypes in human tumors. Immunol Today 1997: 18: 89-95.
    • (1997) Immunol Today , vol.18 , pp. 89-95
    • Garrido, F.1    Ruiz-Cabello, F.2    Cabrera, T.3
  • 3
    • 0034519263 scopus 로고    scopus 로고
    • Tumor escape mechanism involving Fas and Fas-L molecules in human colorectal tumors
    • Radfar S, Martin H, Tilkin-Mariame AF. Tumor escape mechanism involving Fas and Fas-L molecules in human colorectal tumors. Gastroenterol Clin Biol 2000: 24: 1191-6.
    • (2000) Gastroenterol Clin Biol , vol.24 , pp. 1191-1196
    • Radfar, S.1    Martin, H.2    Tilkin-Mariame, A.F.3
  • 5
    • 0035650718 scopus 로고    scopus 로고
    • Deficient expression of components of MHC class I antigen processing machinery in human cervical carcinoma
    • Ritz U, Momburg F, Pilch H, Huber C, Maeurer MJ, Seliger B. Deficient expression of components of MHC class I antigen processing machinery in human cervical carcinoma. Int J Oncol 2001: 19: 1211-20.
    • (2001) Int J Oncol , vol.19 , pp. 1211-1220
    • Ritz, U.1    Momburg, F.2    Pilch, H.3    Huber, C.4    Maeurer, M.J.5    Seliger, B.6
  • 6
    • 0037639186 scopus 로고    scopus 로고
    • MHC class I deficient metastatic tumor variants immunoselected by T lymphocytes are originated by coordinated downregulation of APM components
    • in press
    • Garcia-Lora A, Martinez. M, Algarra I, Gaforio JJ, Garrido F. MHC class I deficient metastatic tumor variants immunoselected by T lymphocytes are originated by coordinated downregulation of APM components. International J Cancer 2003: in press.
    • (2003) International J Cancer
    • Garcia-Lora, A.1    Martinez, M.2    Algarra, I.3    Gaforio, J.J.4    Garrido, F.5
  • 7
    • 0029061997 scopus 로고
    • Quantitative correlation between HLA class I expression and recognition of melanoma cells by antigen specific cytotoxic T lymphocytes
    • Rivoltini L, Barracchini DC, Viggiano V et al. Quantitative correlation between HLA class I expression and recognition of melanoma cells by antigen specific cytotoxic T lymphocytes. Cancer Res 1995: 55: 3149-57.
    • (1995) Cancer Res , vol.55 , pp. 3149-3157
    • Rivoltini, L.1    Barracchini, D.C.2    Viggiano, V.3
  • 8
    • 0035899332 scopus 로고    scopus 로고
    • Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
    • Gayet J, Zhou XP, Duval A et al. Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene 2001: 20: 5025-32.
    • (2001) Oncogene , vol.20 , pp. 5025-5032
    • Gayet, J.1    Zhou, X.P.2    Duval, A.3
  • 9
    • 0035112748 scopus 로고    scopus 로고
    • Investigation of HLA dass I downregulation in breast cancer by RT-PCR
    • Palmisano GL, Pistillo MP, Capanni P et al. Investigation of HLA dass I downregulation in breast cancer by RT-PCR. Hum Immunol 2001: 62: 133-9.
    • (2001) Hum Immunol , vol.62 , pp. 133-139
    • Palmisano, G.L.1    Pistillo, M.P.2    Capanni, P.3
  • 10
    • 0029903029 scopus 로고    scopus 로고
    • Markedly decreased expression of TAP1 and LMP2 genes in HLA class I-deficient human tumor cell lines
    • Singal DP, Ye M, Ni J, Snider DP. Markedly decreased expression of TAP1 and LMP2 genes in HLA class I-deficient human tumor cell lines. Immunol Lett 1996: 50: 149-54.
    • (1996) Immunol Lett , vol.50 , pp. 149-154
    • Singal, D.P.1    Ye, M.2    Ni, J.3    Snider, D.P.4
  • 11
    • 0032529634 scopus 로고    scopus 로고
    • Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines
    • Johnsen A, France J, Sy MS, Harding CV. Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines. Cancer Res 1998: 58: 3660-7.
    • (1998) Cancer Res , vol.58 , pp. 3660-3667
    • Johnsen, A.1    France, J.2    Sy, M.S.3    Harding, C.V.4
  • 12
    • 0035076824 scopus 로고    scopus 로고
    • Lack of HLA-class I antigens in human neuroblastoma cells: Analysis of its relationship to TAP and tapasin expression
    • Corrias MV, Occhino M, Croce M et al. Lack of HLA-class I antigens in human neuroblastoma cells: analysis of its relationship to TAP and tapasin expression. Tissue Antigens 2001: 57: 110-7.
    • (2001) Tissue Antigens , vol.57 , pp. 110-117
    • Corrias, M.V.1    Occhino, M.2    Croce, M.3
  • 13
    • 0034788243 scopus 로고    scopus 로고
    • MHC antigens and tumor escape from immune surveillance
    • Garrido F, Algarra I. MHC antigens and tumor escape from immune surveillance. Adv Cancer Research 2001: 83: 117-58.
    • (2001) Adv Cancer Research , vol.83 , pp. 117-158
    • Garrido, F.1    Algarra, I.2
  • 15
    • 0030964320 scopus 로고    scopus 로고
    • IFNγ-mediated coordinated transcriptional regulation of human TAP1 and LMP2 genes in human renal cell carcinoma
    • Seliger B, Hammers S, Höhne A et al. IFNγ-mediated coordinated transcriptional regulation of human TAP1 and LMP2 genes in human renal cell carcinoma. Clin Cancer Res 1997: 3: 573-8.
    • (1997) Clin Cancer Res , vol.3 , pp. 573-578
    • Seliger, B.1    Hammers, S.2    Höhne, A.3
  • 16
    • 0033014313 scopus 로고    scopus 로고
    • Induction of immunogenicity of a human renal-cell carcinoma cell line by TAP1-gene transfer
    • Kallfelz M, Jung D, Hilmes C et al. Induction of immunogenicity of a human renal-cell carcinoma cell line by TAP1-gene transfer. Int J Cancer 1999: 81: 125-33.
    • (1999) Int J Cancer , vol.81 , pp. 125-133
    • Kallfelz, M.1    Jung, D.2    Hilmes, C.3
  • 17
    • 0032217242 scopus 로고    scopus 로고
    • Mutations of the beta2-microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides
    • Benitez R, Godelaine D, Lopez Nevot MA et al. Mutations of the beta2-microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides. Tissue Antigens 1998: 52: 520-9.
    • (1998) Tissue Antigens , vol.52 , pp. 520-529
    • Benitez, R.1    Godelaine, D.2    Lopez Nevot, M.A.3
  • 18
    • 0032993840 scopus 로고    scopus 로고
    • A new beta 2-microglobulin mutation found in a melanoma tumor cell line
    • Perez B, Benitez R, Fernandez MA et al. A new beta 2-microglobulin mutation found in a melanoma tumor cell line. Tissue Antigens 1999: 53: 569-72.
    • (1999) Tissue Antigens , vol.53 , pp. 569-572
    • Perez, B.1    Benitez, R.2    Fernandez, M.A.3
  • 19
    • 0031856709 scopus 로고    scopus 로고
    • High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas
    • Cabrera T, Collado A, Fernandez MA et al. High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas. Tissue Antigens 1998: 52: 114-23.
    • (1998) Tissue Antigens , vol.52 , pp. 114-123
    • Cabrera, T.1    Collado, A.2    Fernandez, M.A.3
  • 20
    • 0034688186 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal-cancer patients with suspected genetic predisposition
    • Calistri D, Presciuttini S, Buonsanti G et al. Microsatellite instability in colorectal-cancer patients with suspected genetic predisposition. Int J Cancer 2000: 89: 87-91.
    • (2000) Int J Cancer , vol.89 , pp. 87-91
    • Calistri, D.1    Presciuttini, S.2    Buonsanti, G.3
  • 21
    • 0036221744 scopus 로고    scopus 로고
    • Gastrointestinal cancer of the microsatellite mutator phenotype pathway
    • Yamamoto H, Imai K, Perucho M. Gastrointestinal cancer of the microsatellite mutator phenotype pathway. J Gastroenterol 2002: 37: 153-63.
    • (2002) J Gastroenterol , vol.37 , pp. 153-163
    • Yamamoto, H.1    Imai, K.2    Perucho, M.3
  • 22
    • 0030449845 scopus 로고    scopus 로고
    • Selection for beta2-microglobulin mutation in mismatch repair-defective colorectal carcinomas
    • Bicknell DC, Kaklamanis L, Hampson R, Bodmer WF, Karran P. Selection for beta2-microglobulin mutation in mismatch repair-defective colorectal carcinomas. Curr Biol 1996: 6: 1695-7.
    • (1996) Curr Biol , vol.6 , pp. 1695-1697
    • Bicknell, D.C.1    Kaklamanis, L.2    Hampson, R.3    Bodmer, W.F.4    Karran, P.5
  • 23
    • 0028180967 scopus 로고
    • Beta 2-microglobulin gene mutations: A study of established colorectal cell lines and fresh tumors
    • Bicknell DC, Rowan A, Bodmer WF. Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors. Proc Natl Acad Sci U S A 1994: 91: 4751-6.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4751-4756
    • Bicknell, D.C.1    Rowan, A.2    Bodmer, W.F.3
  • 24
    • 0034121316 scopus 로고    scopus 로고
    • Criteria to define HLA haplotype loss in human solid tumors
    • Ramal LM, Feenstra M, van der Zwan AW et al. Criteria to define HLA haplotype loss in human solid tumors. Tissue Antigens 2000: 55: 443-8.
    • (2000) Tissue Antigens , vol.55 , pp. 443-448
    • Ramal, L.M.1    Feenstra, M.2    Van Der Zwan, A.W.3
  • 25
    • 0033695531 scopus 로고    scopus 로고
    • Molecular strategies to define HLA haplotype loss in microdissected tumor cells
    • Ramal LM, Maleno I, Cabrera T et al. Molecular strategies to define HLA haplotype loss in microdissected tumor cells. Human Immunol 2000: 61: 1001-12.
    • (2000) Human Immunol , vol.61 , pp. 1001-1012
    • Ramal, L.M.1    Maleno, I.2    Cabrera, T.3
  • 26
    • 0032952309 scopus 로고    scopus 로고
    • A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Cancer Res 1998: 58: 5248-57
    • Perucho M. Correspondence re: Boland C R et al: A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer (Cancer Res 1998: 58: 5248-57). Cancer Res 1999: 59: 249-53.
    • (1999) Cancer Res , vol.59 , pp. 249-253
    • Perucho, M.1    Boland, C.R.2
  • 27
    • 0032534069 scopus 로고    scopus 로고
    • A national cancer institute workshop on microsatdlite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability
    • Boland CR, Thibodeau SN, Hamilton SR et al. A national cancer institute workshop on microsatdlite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability. Cancer Res 1998: 58: 5248-57.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3
  • 28
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the Bax gene in colon cancers of the microsateilite mutator phenotype
    • Rampino N, Yamamoto H, Ionov Y et al. Somatic frameshift mutations in the Bax gene in colon cancers of the microsateilite mutator phenotype. Science 1997: 275: 967-9.
    • (1997) Science , vol.275 , pp. 967-969
    • Rampino, N.1    Yamamoto, H.2    Ionov, Y.3
  • 29
    • 0027991677 scopus 로고
    • MHC class I expression in mice lacking the proteasome subunit LMP7
    • Fehling HJ, Swat W, Laplace C et al. MHC class I expression in mice lacking the proteasome subunit LMP7. Science 1994: 265: 1234-7.
    • (1994) Science , vol.265 , pp. 1234-1237
    • Fehling, H.J.1    Swat, W.2    Laplace, C.3
  • 30
    • 0033404775 scopus 로고    scopus 로고
    • The nature of the MHC class I peptide loading complex
    • Cresswell P, Bangia N, Dick T, Diedrich G. The nature of the MHC class I peptide loading complex. Immunol Rev 1999: 172: 21-8.
    • (1999) Immunol Rev , vol.172 , pp. 21-28
    • Cresswell, P.1    Bangia, N.2    Dick, T.3    Diedrich, G.4
  • 31
    • 0029828991 scopus 로고    scopus 로고
    • Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
    • Wiertz EJ, Tortorella D, Bogyo M, Yu J et al. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 1996: 384: 432-8.
    • (1996) Nature , vol.384 , pp. 432-438
    • Wiertz, E.J.1    Tortorella, D.2    Bogyo, M.3    Yu, J.4
  • 32
    • 0030070704 scopus 로고    scopus 로고
    • Assembly of ER-associated protein degradation in vitro: Dependence on cytosol, calnexin, and ATP
    • McCracken AA, Brodsky JL. Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP. J Cell Biol 1996: 132: 291-8.
    • (1996) J Cell Biol , vol.132 , pp. 291-298
    • McCracken, A.A.1    Brodsky, J.L.2
  • 33
    • 0036499973 scopus 로고    scopus 로고
    • Visualization of ER-to-cytosol dislocation reaction of a type I membrane protein
    • Fiebiger E, Story C, Ploegh HL, Tortorella D. Visualization of ER-to-cytosol dislocation reaction of a type I membrane protein. EMBO J 2002: 21: 1041-53.
    • (2002) EMBO J , vol.21 , pp. 1041-1053
    • Fiebiger, E.1    Story, C.2    Ploegh, H.L.3    Tortorella, D.4
  • 34
    • 0031051852 scopus 로고    scopus 로고
    • Misfolded major histocompatibility complex class I heavy chains are transloeated into the cytoplasm and degraded by the proteasome
    • Hughes EA, Hammond C, Cresswell P. Misfolded major histocompatibility complex class I heavy chains are transloeated into the cytoplasm and degraded by the proteasome. Proc Natl Acad Sci U S A 1997: 94: 1896-901.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1896-1901
    • Hughes, E.A.1    Hammond, C.2    Cresswell, P.3
  • 35
    • 0032032682 scopus 로고    scopus 로고
    • Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in Hereditary Nonpolyposis Colorectal Cancer
    • Yamamoto H, Sawai H, Weber TK, Rodrignez-Bigas MA, Perucho M. Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in Hereditary Nonpolyposis Colorectal Cancer. Cancer Res 1998: 58: 997-1003.
    • (1998) Cancer Res , vol.58 , pp. 997-1003
    • Yamamoto, H.1    Sawai, H.2    Weber, T.K.3    Rodrignez-Bigas, M.A.4    Perucho, M.5
  • 36
    • 0033038815 scopus 로고    scopus 로고
    • Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features
    • Yamamoto H, Perez-Piteira J, Yoshida T et al. Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features. Gastroenterology 1999: 116: 1348-57.
    • (1999) Gastroenterology , vol.116 , pp. 1348-1357
    • Yamamoto, H.1    Perez-Piteira, J.2    Yoshida, T.3
  • 37
    • 0034744610 scopus 로고    scopus 로고
    • Somatic mutation of the beta2-microgiobulin gene associates with unfavorable prognosis in gastrointestinal cancer of the microsatellite mutator phenotype
    • Yamamoto H, Yamashita K, Perucho M. Somatic mutation of the beta2-microgiobulin gene associates with unfavorable prognosis in gastrointestinal cancer of the microsatellite mutator phenotype. Gastroenterology 2001: 120: 1565-7.
    • (2001) Gastroenterology , vol.120 , pp. 1565-1567
    • Yamamoto, H.1    Yamashita, K.2    Perucho, M.3
  • 38
    • 0033778049 scopus 로고    scopus 로고
    • Microsatellite instability is a favourable prognostic indicator in patients with colorectal cancer receiving chemotherapy
    • Hemminki A, Mecklin JP, Järvinen H, Aaltonen LA, Joensuu H. Microsatellite instability is a favourable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology 2000: 119: 921-8.
    • (2000) Gastroenterology , vol.119 , pp. 921-928
    • Hemminki, A.1    Mecklin, J.P.2    Järvinen, H.3    Aaltonen, L.A.4    Joensuu, H.5
  • 39
    • 0034840021 scopus 로고    scopus 로고
    • Expression of HLA class II in colorectal cancer: Evidence for enhanced immunogenicity of microsatellite-instability-positive tumors
    • Bustin SA, Li SR, Phillips S, Dorudi S. Expression of HLA class II in colorectal cancer: evidence for enhanced immunogenicity of microsatellite-instability-positive tumors. Tumor Biol 2001: 22: 294-8.
    • (2001) Tumor Biol , vol.22 , pp. 294-298
    • Bustin, S.A.1    Li, S.R.2    Phillips, S.3    Dorudi, S.4
  • 40
    • 0036155882 scopus 로고    scopus 로고
    • Impaired surface antigen presentation in tumors: Implications for T cell-based immunotherapy
    • Ruiz-Cabello F, Cabrera T, Lopez-Nevot MA, Garrido F. Impaired surface antigen presentation in tumors: implications for T cell-based immunotherapy. Semin Cancer Biol 2002: 12: 15-24.
    • (2002) Semin Cancer Biol , vol.12 , pp. 15-24
    • Ruiz-Cabello, F.1    Cabrera, T.2    Lopez-Nevot, M.A.3    Garrido, F.4
  • 41
    • 0034201385 scopus 로고    scopus 로고
    • The expression of MHC class I, TAP1/TAP2, and LMP2/7 genes in human cancer cell lines
    • Kang JK, Yoon SJ, Kim NK, Heo DS. The expression of MHC class I, TAP1/TAP2, and LMP2/7 genes in human cancer cell lines. Int J Oncol 2000: 16: 1159-63.
    • (2000) Int J Oncol , vol.16 , pp. 1159-1163
    • Kang, J.K.1    Yoon, S.J.2    Kim, N.K.3    Heo, D.S.4
  • 42
    • 0034667381 scopus 로고    scopus 로고
    • Loss of interferon-gamma inducibility of TAP1 and LMP2 in a renal cell carcinoma cell line
    • Dovhey SE, Ghosh NS, Wright KL. Loss of interferon-gamma inducibility of TAP1 and LMP2 in a renal cell carcinoma cell line. Cancer Res 2000: 60: 5789-96.
    • (2000) Cancer Res , vol.60 , pp. 5789-5796
    • Dovhey, S.E.1    Ghosh, N.S.2    Wright, K.L.3
  • 43
    • 0034056103 scopus 로고    scopus 로고
    • Reduced expression of MHC class I antigen in human cancer cell lines with defective LMP-7
    • Yoon SJ, Kang JO, Park JS, Kim NK, Heo DS. Reduced expression of MHC class I antigen in human cancer cell lines with defective LMP-7. Anticancer Res 2000: 20: 949-53.
    • (2000) Anticancer Res , vol.20 , pp. 949-953
    • Yoon, S.J.1    Kang, J.O.2    Park, J.S.3    Kim, N.K.4    Heo, D.S.5


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