-
1
-
-
0033525086
-
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation
-
DOI 10.1074/jbc.274.6.3363
-
Kisselev, A. F., T. N. Akopian, K. M. Woo, and A. L. Goldberg. 1999. The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes: implications for understanding the degradative mechanism and antigen presentation. J. Biol. Chem. 274: 3363-3371. (Pubitemid 29077173)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.6
, pp. 3363-3371
-
-
Kisselev, A.F.1
Akopian, T.N.2
Woo, K.M.3
Goldberg, A.L.4
-
2
-
-
0035873704
-
26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide
-
DOI 10.1093/emboj/20.10.2357
-
Cascio, P., C. Hilton, A. F. Kisselev, K. L. Rock, and A. L. Goldberg. 2001. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J. 20: 2357-2366. (Pubitemid 32452853)
-
(2001)
EMBO Journal
, vol.20
, Issue.10
, pp. 2357-2366
-
-
Cascio, P.1
Hilton, C.2
Kisselev, A.F.3
Rock, K.L.4
Goldberg, A.L.5
-
3
-
-
67650465638
-
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
-
Saveanu, L., O. Carroll, M. Weimershaus, P. Guermonprez, E. Firat, V. Lindo, F. Greer, J. Davoust, R. Kratzer, S. R. Keller, et al. 2009. IRAP identifies an endosomal compartment required for MHC class I cross-presentation. Science 325: 213-217.
-
(2009)
Science
, vol.325
, pp. 213-217
-
-
Saveanu, L.1
Carroll, O.2
Weimershaus, M.3
Guermonprez, P.4
Firat, E.5
Lindo, V.6
Greer, F.7
Davoust, J.8
Kratzer, R.9
Keller, S.R.10
-
4
-
-
84856876931
-
Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation
-
Weimershaus, M., S. Maschalidi, F. Sepulveda, B. Manoury, P. van Endert, and L. Saveanu. 2012. Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation. J. Immunol. 188: 1840-1846.
-
(2012)
J. Immunol.
, vol.188
, pp. 1840-1846
-
-
Weimershaus, M.1
Maschalidi, S.2
Sepulveda, F.3
Manoury, B.4
Van Endert, P.5
Saveanu, L.6
-
5
-
-
0042357061
-
Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases
-
DOI 10.1074/jbc.M305076200
-
Tanioka, T., A. Hattori, S. Masuda, Y. Nomura, H. Nakayama, S. Mizutani, and M. Tsujimoto. 2003. Human leukocyte-derived arginine aminopeptidase: the third member of the oxytocinase subfamily of aminopeptidases. J. Biol. Chem. 278: 32275-32283. (Pubitemid 37048421)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.34
, pp. 32275-32283
-
-
Tanioka, T.1
Hattori, A.2
Masuda, S.3
Nomura, Y.4
Nakayama, H.5
Mizutani, S.6
Tsujimoto, M.7
-
6
-
-
78149277185
-
Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection
-
Cagliani, R., S. Riva, M. Biasin, M. Fumagalli, U. Pozzoli, S. Lo Caputo, F. Mazzotta, L. Piacentini, N. Bresolin, M. Clerici, and M. Sironi. 2010. Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection. Hum. Mol. Genet. 19: 4705-4714.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4705-4714
-
-
Cagliani, R.1
Riva, S.2
Biasin, M.3
Fumagalli, M.4
Pozzoli, U.5
Lo Caputo, S.6
Mazzotta, F.7
Piacentini, L.8
Bresolin, N.9
Clerici, M.10
Sironi, M.11
-
7
-
-
77955332608
-
Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential
-
Haroon, N., and R. D. Inman. 2010. Endoplasmic reticulum aminopeptidases: biology and pathogenic potential. Nat. Rev. Rheumatol. 6: 461-467.
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 461-467
-
-
Haroon, N.1
Inman, R.D.2
-
8
-
-
65349123542
-
Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma
-
Mehta, A. M., E. S. Jordanova, W. E. Corver, T. van Wezel, H. W. Uh, G. G. Kenter, and G. Jan Fleuren. 2009. Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma. Genes Chromosomes Cancer 48: 410-418.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 410-418
-
-
Mehta, A.M.1
Jordanova, E.S.2
Corver, W.E.3
Van Wezel, T.4
Uh, H.W.5
Kenter, G.G.6
Jan Fleuren, G.7
-
9
-
-
0033056047
-
Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase
-
Hattori, A., H. Matsumoto, S. Mizutani, and M. Tsujimoto. 1999. Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase. J. Biochem. 125: 931-938. (Pubitemid 29253563)
-
(1999)
Journal of Biochemistry
, vol.125
, Issue.5
, pp. 931-938
-
-
Hattori, A.1
Matsumoto, H.2
Mizutani, S.3
Tsujimoto, M.4
-
10
-
-
22144442460
-
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum
-
DOI 10.1038/ni1208
-
Saveanu, L., O. Carroll, V. Lindo, M. Del Val, D. Lopez, Y. Lepelletier, F. Greer, L. Schomburg, D. Fruci, G. Niedermann, and P. M. van Endert. 2005. Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nat. Immunol. 6: 689-697. (Pubitemid 41716742)
-
(2005)
Nature Immunology
, vol.6
, Issue.7
, pp. 689-697
-
-
Saveanu, L.1
Carroll, O.2
Lindo, V.3
Del, V.M.4
Lopez, D.5
Lepelletier, Y.6
Greer, F.7
Schomburg, L.8
Fruci, D.9
Niedermann, G.10
Van Endert, P.M.11
-
11
-
-
79953203538
-
Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides
-
Zervoudi, E., A. Papakyriakou, D. Georgiadou, I. Evnouchidou, A. Gajda, M. Poreba, G. S. Salvesen, M. Drag, A. Hattori, L. Swevers, et al. 2011. Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides. Biochem. J. 435: 411-420.
-
(2011)
Biochem. J.
, vol.435
, pp. 411-420
-
-
Zervoudi, E.1
Papakyriakou, A.2
Georgiadou, D.3
Evnouchidou, I.4
Gajda, A.5
Poreba, M.6
Salvesen, G.S.7
Drag, M.8
Hattori, A.9
Swevers, L.10
-
12
-
-
28044456942
-
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism
-
DOI 10.1073/pnas.0500721102
-
Chang, S. C., F. Momburg, N. Bhutani, and A. L. Goldberg. 2005. The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism. Proc. Natl. Acad. Sci. USA 102: 17107-17112. (Pubitemid 41692691)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.47
, pp. 17107-17112
-
-
Chang, S.-C.1
Momburg, F.2
Bhutani, N.3
Goldberg, A.L.4
-
13
-
-
84865421949
-
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing
-
Evnouchidou, I., J. Birtley, S. Seregin, A. Papakyriakou, E. Zervoudi, M. Samiotaki, G. Panayotou, P. Giastas, O. Petrakis, D. Georgiadis, et al. 2012. A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. J. Immunol. 189: 2383-2392.
-
(2012)
J. Immunol.
, vol.189
, pp. 2383-2392
-
-
Evnouchidou, I.1
Birtley, J.2
Seregin, S.3
Papakyriakou, A.4
Zervoudi, E.5
Samiotaki, M.6
Panayotou, G.7
Giastas, P.8
Petrakis, O.9
Georgiadis, D.10
-
14
-
-
56349128364
-
The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1
-
Evnouchidou, I., F. Momburg, A. Papakyriakou, A. Chroni, L. Leondiadis, S. C. Chang, A. L. Goldberg, and E. Stratikos. 2008. The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1. PLoS One 3: e3658.
-
(2008)
PLoS One
, vol.3
-
-
Evnouchidou, I.1
Momburg, F.2
Papakyriakou, A.3
Chroni, A.4
Leondiadis, L.5
Chang, S.C.6
Goldberg, A.L.7
Stratikos, E.8
-
15
-
-
0028501327
-
A sequential model for peptide binding and transport by the transporters associated with antigen processing
-
van Endert, P. M., R. Tampé, T. H. Meyer, R. Tisch, J. F. Bach, and H. O. McDevitt. 1994. A sequential model for peptide binding and transport by the transporters associated with antigen processing. Immunity 1: 491-500.
-
(1994)
Immunity
, vol.1
, pp. 491-500
-
-
Van Endert, P.M.1
Tampé, R.2
Meyer, T.H.3
Tisch, R.4
Bach, J.F.5
McDevitt, H.O.6
-
16
-
-
79955638487
-
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1
-
Nguyen, T. T., S. C. Chang, I. Evnouchidou, I. A. York, C. Zikos, K. L. Rock, A. L. Goldberg, E. Stratikos, and L. J. Stern. 2011. Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat. Struct. Mol. Biol. 18: 604-613.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 604-613
-
-
Nguyen, T.T.1
Chang, S.C.2
Evnouchidou, I.3
York, I.A.4
Zikos, C.5
Rock, K.L.6
Goldberg, A.L.7
Stratikos, E.8
Stern, L.J.9
-
17
-
-
33846988640
-
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides
-
DOI 10.1038/ni1409, PII NI1409
-
Hammer, G. E., F. Gonzalez, E. James, H. Nolla, and N. Shastri. 2007. In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat. Immunol. 8: 101-108. (Pubitemid 46242364)
-
(2007)
Nature Immunology
, vol.8
, Issue.1
, pp. 101-108
-
-
Hammer, G.E.1
Gonzalez, F.2
James, E.3
Nolla, H.4
Shastri, N.5
-
18
-
-
29244461714
-
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
-
DOI 10.1038/ni1286, PII N1286
-
Hammer, G. E., F. Gonzalez, M. Champsaur, D. Cado, and N. Shastri. 2006. The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nat. Immunol. 7: 103-112. (Pubitemid 41823874)
-
(2006)
Nature Immunology
, vol.7
, Issue.1
, pp. 103-112
-
-
Hammer, G.E.1
Gonzalez, F.2
Champsaur, M.3
Cado, D.4
Shastri, N.5
-
19
-
-
33645089946
-
In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules
-
Yan, J., V. V. Parekh, Y. Mendez-Fernandez, D. Olivares- Villagómez, S. Dragovic, T. Hill, D. C. Roopenian, S. Joyce, and L. Van Kaer. 2006. In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J. Exp. Med. 203: 647-659.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 647-659
-
-
Yan, J.1
Parekh, V.V.2
Mendez-Fernandez, Y.3
Olivares-Villagómez, D.4
Dragovic, S.5
Hill, T.6
Roopenian, D.C.7
Joyce, S.8
Van Kaer, L.9
-
20
-
-
33745125912
-
Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance
-
DOI 10.1073/pnas.0603095103
-
York, I. A., M. A. Brehm, S. Zendzian, C. F. Towne, and K. L. Rock. 2006. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc. Natl. Acad. Sci. USA 103: 9202-9207. (Pubitemid 43902556)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.24
, pp. 9202-9207
-
-
York, I.A.1
Brehm, M.A.2
Zendzian, S.3
Towne, C.F.4
Rock, K.L.5
-
21
-
-
84856935252
-
The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing
-
Birtley, J. R., E. Saridakis, E. Stratikos, and I. M. Mavridis. 2012. The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing. Biochemistry 51: 286-295.
-
(2012)
Biochemistry
, vol.51
, pp. 286-295
-
-
Birtley, J.R.1
Saridakis, E.2
Stratikos, E.3
Mavridis, I.M.4
-
22
-
-
1242298599
-
A chaperone-assisted high yield system for the production of HLA-DR4 tetramers in insect cells
-
DOI 10.1016/j.jim.2003.11.011
-
Fourneau, J. M., H. Cohen, and P. M. van Endert. 2004. A chaperone-assisted high yield system for the production of HLA-DR4 tetramers in insect cells. J. Immunol. Methods 285: 253-264. (Pubitemid 38228485)
-
(2004)
Journal of Immunological Methods
, vol.285
, Issue.2
, pp. 253-264
-
-
Fourneau, J.-M.1
Cohen, H.2
Van Endert, P.M.3
-
23
-
-
0036902105
-
An IFN-gamma-induced aminopeptidase in the ER, ERAP I, trims precursors to MHC class I-presented peptides
-
DOI 10.1038/ni859
-
Saric, T., S. C. Chang, A. Hattori, I. A. York, S. Markant, K. L. Rock, M. Tsujimoto, and A. L. Goldberg. 2002. An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat. Immunol. 3: 1169-1176. (Pubitemid 35476828)
-
(2002)
Nature Immunology
, vol.3
, Issue.12
, pp. 1169-1176
-
-
Saric, T.1
Chang, S.-C.2
Hattori, A.3
York, I.A.4
Markant, S.5
Rock, K.L.6
Tsujimoto, M.7
Goldberg, A.L.8
-
24
-
-
0034913229
-
ER aminopeptidases generate a unique pool of peptides for MHC class I molecules
-
DOI 10.1038/89800
-
Serwold, T., S. Gaw, and N. Shastri. 2001. ER aminopeptidases generate a unique pool of peptides for MHC class I molecules. Nat. Immunol. 2: 644-651. (Pubitemid 32677633)
-
(2001)
Nature Immunology
, vol.2
, Issue.7
, pp. 644-651
-
-
Serwold, T.1
Gaw, S.2
Shastri, N.3
-
25
-
-
77956419148
-
Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1
-
Georgiadou, D., A. Hearn, I. Evnouchidou, A. Chroni, L. Leondiadis, I. A. York, K. L. Rock, and E. Stratikos. 2010. Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. J. Immunol. 185: 1584-1592.
-
(2010)
J. Immunol.
, vol.185
, pp. 1584-1592
-
-
Georgiadou, D.1
Hearn, A.2
Evnouchidou, I.3
Chroni, A.4
Leondiadis, L.5
York, I.A.6
Rock, K.L.7
Stratikos, E.8
-
26
-
-
0035422908
-
Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors
-
Luckey, C. J., J. A. Marto, M. Partridge, E. Hall, F. M. White, J. D. Lippolis, J. Shabanowitz, D. F. Hunt, and V. H. Engelhard. 2001. Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors. J. Immunol. 167: 1212-1221. (Pubitemid 32703115)
-
(2001)
Journal of Immunology
, vol.167
, Issue.3
, pp. 1212-1221
-
-
Luckey, C.J.1
Marto, J.A.2
Partridge, M.3
Hall, E.4
White, F.M.5
Lippolis, J.D.6
Shabanowitz, J.7
Hunt, D.F.8
Engelhard, V.H.9
-
27
-
-
0036570715
-
Stabilization of soluble, low-affinity HLA-DM/HLA-DR1 complexes by leucine zippers
-
DOI 10.1016/S0022-1759(02)00034-0, PII S0022175902000340
-
Busch, R., A. Pashine, K. C. Garcia, and E. D. Mellins. 2002. Stabilization of soluble, low-affinity HLA-DM/HLA-DR1 complexes by leucine zippers. J. Immunol. Methods 263: 111-121. (Pubitemid 34493814)
-
(2002)
Journal of Immunological Methods
, vol.263
, Issue.1-2
, pp. 111-121
-
-
Busch, R.1
Pashine, A.2
Garcia, K.C.3
Mellins, E.D.4
-
28
-
-
0028134881
-
A general method for facilitating heterodimeric pairing between two proteins: Application to expression of alpha and beta T-cell receptor extracellular segments
-
DOI 10.1073/pnas.91.24.11408
-
Chang, H. C., Z. Bao, Y. Yao, A. G. Tse, E. C. Goyarts, M. Madsen, E. Kawasaki, P. P. Brauer, J. C. Sacchettini, S. G. Nathenson, et al. 1994. A general method for facilitating heterodimeric pairing between two proteins: application to expression of alpha and beta T-cell receptor extracellular segments. Proc. Natl. Acad. Sci. USA 91: 11408-11412. (Pubitemid 24356353)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.24
, pp. 11408-11412
-
-
Chang, H.-C.1
Bao, Z.-Z.2
Yao, Y.3
Tse, A.G.D.4
Goyarts, E.C.5
Madsen, M.6
Kawasaki, E.7
Brauer, P.P.8
Sacchettini, J.C.9
Nathenson, S.G.10
Reinherz, E.L.11
-
29
-
-
33947606283
-
Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection
-
DOI 10.1038/sj.emboj.7601624, PII 7601624
-
Chen, M., and M. Bouvier. 2007. Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection. EMBO J. 26: 1681-1690. (Pubitemid 46480944)
-
(2007)
EMBO Journal
, vol.26
, Issue.6
, pp. 1681-1690
-
-
Chen, M.1
Bouvier, M.2
-
30
-
-
0029808087
-
Expression of recombinant HLA-DR2 molecules: Replacement of the hydrophobic transmembrane region by a leucine zipper dimerization motif allows the assembly and secretion of soluble DR alpha beta heterodimers
-
Kalandadze, A., M. Galleno, L. Foncerrada, J. L. Strominger, and K. W. Wucherpfennig. 1996. Expression of recombinant HLA-DR2 molecules: replacement of the hydrophobic transmembrane region by a leucine zipper dimerization motif allows the assembly and secretion of soluble DR alpha beta heterodimers. J. Biol. Chem. 271: 20156-20162.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20156-20162
-
-
Kalandadze, A.1
Galleno, M.2
Foncerrada, L.3
Strominger, J.L.4
Wucherpfennig, K.W.5
-
31
-
-
0029979998
-
Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules
-
DOI 10.1084/jem.183.5.2087
-
Scott, C. A., K. C. Garcia, F. R. Carbone, I. A. Wilson, and L. Teyton. 1996. Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules. J. Exp. Med. 183: 2087-2095. (Pubitemid 26158901)
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.5
, pp. 2087-2095
-
-
Scott, C.A.1
Garcia, K.C.2
Carbone, F.R.3
Wilson, I.A.4
Teyton, L.5
-
32
-
-
34547121970
-
Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer
-
DOI 10.1038/ni1485, PII NI1485
-
Wearsch, P. A., and P. Cresswell. 2007. Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer. Nat. Immunol. 8: 873-881. (Pubitemid 47099039)
-
(2007)
Nature Immunology
, vol.8
, Issue.8
, pp. 873-881
-
-
Wearsch, P.A.1
Cresswell, P.2
|