The anti-ageing hormone klotho induces Nrf2-mediated antioxidant defences in human aortic smooth muscle cells

Journal of Cellular and Molecular Medicine

Volumn 21, Issue 3, 2017, Pages 621-627

  Maltese, Giuseppe ^a   Psefteli, Paraskevi Maria ^a   Rizzo, Benedetta ^b   Srivastava, Salil ^a   Gnudi, Luigi ^a   Mann, Giovanni E ^a   Siow, Richard C M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

ageing; angiotensin II; antioxidant; atherosclerosis; glutathione; haeme oxygenase 1; Klotho; Nrf2; peroxiredoxin 1; vascular smooth muscle

Indexed keywords

ANGIOTENSIN II; GLUTATHIONE; HEME OXYGENASE; HUMAN RECOMBINANT SOLUBLE KLOTHO; KLOTHO PROTEIN; PEROXIREDOXIN 1; RECOMBINANT PROTEIN; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; BETA GLUCURONIDASE; HEME OXYGENASE 1;

AGING; ANTIOXIDANT ACTIVITY; AORTIC SMOOTH MUSCLE CELL; APOPTOSIS; APOPTOSIS ASSAY; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DRUG MECHANISM; FLUOROMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; AORTA; CELL CULTURE; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CELL; VASCULAR SMOOTH MUSCLE;

AGING; ANGIOTENSIN II; ANTIOXIDANTS; AORTA; APOPTOSIS; CELLS, CULTURED; GLUCURONIDASE; GLUTATHIONE; HEME OXYGENASE-1; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84990212633     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12996     Document Type: Article

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