메뉴 건너뛰기




Volumn 44, Issue 4, 2012, Pages 375-393

A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-transport (SGLT) inhibitors. Systematic review and meta-analysis of randomized trials

Author keywords

BI 10773; Canagliflozin; Dapagliflozin; Diabetes; Diabetes treatment; Hyperglycemia; LX4211; Meta analysis; Renal glucose transporters; Sodium glucose co transport 2 (SGLT2) inhibitors

Indexed keywords

ANTIDIABETIC AGENT; CALCIUM; CANAGLIFLOZIN; CREATININE; DAPAGLIFLOZIN; EMPAGLIFLOZIN; GLIMEPIRIDE; GLITAZONE DERIVATIVE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LX 4211; METFORMIN; ORAL ANTIDIABETIC AGENT; PLACEBO; POTASSIUM; PROTEIN INHIBITOR; SODIUM; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SULFONYLUREA DERIVATIVE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URIC ACID;

EID: 84860183617     PISSN: 07853890     EISSN: 13652060     Source Type: Journal    
DOI: 10.3109/07853890.2011.560181     Document Type: Review
Times cited : (249)

References (41)
  • 1
    • 75149130955 scopus 로고    scopus 로고
    • Position statement. Diagnosis and classifi cation of diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association. Position statement. Diagnosis and classifi cation of diabetes mellitus. Diabetes Care. 2010;33(Suppl1);S62-9.
    • (2010) Diabetes Care , vol.33 , Issue.SUPPL. 1
  • 2
    • 0027370108 scopus 로고
    • The Diabetes Control and Complications Trial Research Group
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulindependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993; 329:977-86.
    • (1993) N Engl J Med , vol.329 , pp. 977-86
  • 4
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • DOI 10.2337/diabetes.54.6.1615
    • Brownlee M. The pathobiology of diabetic complications. A unifying mechanism. Diabetes. 2005;54:1615-25. (Pubitemid 40770750)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
    • Brownlee, M.1
  • 5
    • 0030837469 scopus 로고    scopus 로고
    • Glucose: A continuous risk factor for cardiovascular disease
    • DOI 10.1002/(SICI)1096-9136(199708)14:3+3.0.CO;2-1
    • Gerstein HC. Glucose: a continuous risk factor for cardiovascular disease. Diabet Med. 1997;14(Suppl 3):S25-31. (Pubitemid 27346843)
    • (1997) Diabetic Medicine , vol.14 , Issue.SUPPL. 3
    • Gerstein, H.C.1
  • 7
    • 33750469241 scopus 로고    scopus 로고
    • Position statement. Standards of medical care in diabetes-2010
    • American Diabetes Association
    • American Diabetes Association. Position statement. Standards of medical care in diabetes-2010. Diabetes Care. 2010;33 (Suppl1):S23.
    • (2010) Diabetes Care , vol.33 , Issue.SUPPL. 1
  • 8
    • 0032983666 scopus 로고    scopus 로고
    • Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus. Progressive requirement for multiple therapies (UKPDS 49)
    • DOI 10.1001/jama.281.21.2005
    • Turner RC, Cull CA, Frighi V, Holman RR. Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. JAMA. 1999;281;2005-12. (Pubitemid 29254858)
    • (1999) Journal of the American Medical Association , vol.281 , Issue.21 , pp. 2005-2012
    • Turner, R.C.1    Cull, C.A.2    Frighi, V.3    Holman, R.R.4
  • 10
    • 77954242599 scopus 로고    scopus 로고
    • SGLT2 inhibition: A novel strategy for diabetes treatment
    • Chao EC, Henry RR. SGLT2 inhibition: a novel strategy for diabetes treatment. Nat Rev Drug Discov. 2010;9:551-9.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 551-9
    • Chao, E.C.1    Henry, R.R.2
  • 11
    • 67349189212 scopus 로고    scopus 로고
    • Renal sodium-glucose transport: Role in diabetes mellitus and potential clinical implications
    • Bakris GL, Fonseca VA, Sharma K, Wright EM. Renal sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Kidney Int. 2009;75:1272-7.
    • (2009) Kidney Int , vol.75 , pp. 1272-7
    • Bakris, G.L.1    Fonseca, V.A.2    Sharma, K.3    Wright, E.M.4
  • 12
    • 75749094398 scopus 로고    scopus 로고
    • Familial renal glucosuria and SGLT2: From a mendelian trait to a therapeutic target
    • Santer R, Calado J. Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target. Clin Am Soc Nephrol. 2010;5:133-41.
    • (2010) Clin Am Soc Nephrol , vol.5 , pp. 133-41
    • Santer, R.1    Calado, J.2
  • 13
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • DOI 10.2337/diabetes.54.12.3427
    • Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with noninsulindependent diabetes. Diabetes. 2005;54:3427-34. (Pubitemid 43334332)
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3    Smith, C.D.4    Hong, G.5    Brown, J.6
  • 16
    • 0023275573 scopus 로고
    • Correction of hyperglycemia with phlorizin normalizes tissues sensitivity to insulin in diabetic rats
    • Rossetti L, Shulman GI, Papachristou D, DeFronzo RA. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest. 1987; 79:1510-5. (Pubitemid 17099657)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.5 , pp. 1510-1515
    • Rossetti, L.1    Smith, D.2    Shulman, G.I.3
  • 19
    • 84925548115 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. J Clin Epidemiol. 2009;62:1006-12.
    • (2009) J Clin Epidemiol , vol.62 , pp. 1006-12
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 20
    • 65349196064 scopus 로고    scopus 로고
    • Sodiumglucose cotransport inhibition with dapaglifl ozin in type 2 diabetes
    • List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodiumglucose cotransport inhibition with dapaglifl ozin in type 2 diabetes. Diabetes Care. 2009;32:650-7.
    • (2009) Diabetes Care , vol.32 , pp. 650-7
    • List, J.F.1    Woo, V.2    Morales, E.3    Tang, W.4    Fiedorek, F.T.5
  • 21
    • 67349275999 scopus 로고    scopus 로고
    • Dapaglifl ozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus
    • Komoroski B, Vachharajani N, Feng Y, Li L, Kornhauser D, Pfi ster M. Dapaglifl ozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther. 2009;85:513-9.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 513-9
    • Komoroski, B.1    Vachharajani, N.2    Feng, Y.3    Li, L.4    Kornhauser, D.5    Pfister, M.6
  • 22
    • 69549095914 scopus 로고    scopus 로고
    • A study of dapaglifl ozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers: Applicability of a novel insulin-independent treatment
    • Wilding JP, Norwood P, T 'j oen C, Bastien A, List JF, Fiedorek FT. A study of dapaglifl ozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers: applicability of a novel insulin-independent treatment. Diabetes Care. 2009;32:1656-62.
    • (2009) Diabetes Care , vol.32 , pp. 1656-62
    • Wilding, J.P.1    Norwood, P.2    T'J Oen, C.3    Bastien, A.4    List, J.F.5    Fiedorek, F.T.6
  • 23
    • 79952731529 scopus 로고    scopus 로고
    • Sustained effectiveness of dapaglifl ozin over 48 weeks in patients with type 2 diabetes poorly controlled with insulin
    • Wilding JPH, Woo V, Pahor A, Sugg J, Langkilde A, Parikh S. Sustained effectiveness of dapaglifl ozin over 48 weeks in patients with type 2 diabetes poorly controlled with insulin. Diabetologia. 2010;53(S1):S348-9.
    • (2010) Diabetologia , vol.53 , Issue.S1
    • Wilding, J.P.H.1    Woo, V.2    Pahor, A.3    Sugg, J.4    Langkilde, A.5    Parikh, S.6
  • 24
    • 77953857048 scopus 로고    scopus 로고
    • Effect of dapaglifl ozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
    • Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapaglifl ozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375: 2223-33.
    • (2010) Lancet , vol.375 , pp. 2223-33
    • Bailey, C.J.1    Gross, J.L.2    Pieters, A.3    Bastien, A.4    List, J.F.5
  • 25
    • 77956921439 scopus 로고    scopus 로고
    • Dapaglifl ozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: A randomized, double-blind, placebo-controlled, phase III trial
    • Ferrannini E, Jimenez Ramos S, Salsali A, Tang W, List JF. Dapaglifl ozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase III trial. Diabetes Care. 2010;33:2217-24.
    • (2010) Diabetes Care , vol.33 , pp. 2217-24
    • Ferrannini, E.1    Jimenez Ramos, S.2    Salsali, A.3    Tang, W.4    List, J.F.5
  • 26
    • 79952731806 scopus 로고    scopus 로고
    • Effi cacy and safety of dapaglifl ozin in patients with type 2 diabetes mellitus and inadequate glycaemic control on glimepiride monotherapy
    • Strojek K, Hruba V, Elze M, Langkilde A, Parikh S. Effi cacy and safety of dapaglifl ozin in patients with type 2 diabetes mellitus and inadequate glycaemic control on glimepiride monotherapy. Diabetologia. 2010;53(S1):S347-8.
    • (2010) Diabetologia , vol.53 , Issue.S1
    • Strojek, K.1    Hruba, V.2    Elze, M.3    Langkilde, A.4    Parikh, S.5
  • 27
    • 80052815931 scopus 로고    scopus 로고
    • Canaglifl ozin, an inhibitor of sodium glucose cotransporter 2, improves glycaemic control, lowers body weight, and improves beta cell function in subjects with type 2 diabetes on background metformin
    • Rosenstock J, Polidori D, Zhao Y, Sha S, Arbit D, Usiskin K, et al. Canaglifl ozin, an inhibitor of sodium glucose cotransporter 2, improves glycaemic control, lowers body weight, and improves beta cell function in subjects with type 2 diabetes on background metformin. Diabetologia. 2010; 53(S1):S349.
    • (2010) Diabetologia , vol.53 , Issue.S1
    • Rosenstock, J.1    Polidori, D.2    Zhao, Y.3    Sha, S.4    Arbit, D.5    Usiskin, K.6
  • 28
    • 80052818701 scopus 로고    scopus 로고
    • Canaglifl ozin, a novel inhibitor of sodium glucose co-transporter 2, improved glucose control in subjects with type 2 diabetes: Results of a phase 1b study
    • Rothenberg PL, Devineni D, Ghosh A, Polidori AD, Hompesch M, Arnolds S, et al. Canaglifl ozin, a novel inhibitor of sodium glucose co-transporter 2, improved glucose control in subjects with type 2 diabetes: Results of a phase 1b study. Diabetologia. 2010;53(S1):S350-1.
    • (2010) Diabetologia , vol.53 , Issue.S1
    • Rothenberg, P.L.1    Devineni, D.2    Ghosh, A.3    Polidori, A.D.4    Hompesch, M.5    Arnolds, S.6
  • 29
    • 79960311276 scopus 로고    scopus 로고
    • The potent and highly selective sodium-glucose co-cransporter (SGLT-2) inhibitor BI 10773 is safe and effi cacious as monotherapy in patients with type 2 diabetes mellitus
    • Ferrannini E, Seman LI, Seewaldt-Becker E, Hantel S, Pannetti S, Woerle HJ. The potent and highly selective sodium-glucose co-cransporter (SGLT-2) inhibitor BI 10773 is safe and effi cacious as monotherapy in patients with type 2 diabetes mellitus. Diabetologia. 2010;53(S1):S351.
    • (2010) Diabetologia , vol.53 , Issue.S1
    • Ferrannini, E.1    Seman, L.I.2    Seewaldt-Becker, E.3    Hantel, S.4    Pannetti, S.5    Woerle, H.J.6
  • 34
    • 80052818523 scopus 로고    scopus 로고
    • Canaglifl ozin lowers the renal threshold for glucose excretion in lean, obese and type 2 diabetic subjects
    • Polidori D, Sha S, Sarich T, Devineni D, Rothenberg PL. Canaglifl ozin lowers the renal threshold for glucose excretion in lean, obese and type 2 diabetic subjects. Diabetologia. 2010;53(Suppl1):S350.
    • (2010) Diabetologia , vol.53 , Issue.SUPPL. 1
    • Polidori, D.1    Sha, S.2    Sarich, T.3    Devineni, D.4    Rothenberg, P.L.5
  • 37
    • 77957254503 scopus 로고    scopus 로고
    • The novel sodium glucose transporter 2 inhibitor dapaglifl ozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats
    • Macdonald FR, Peel JE, Jones HB, Mayers RM, Westgate L, Whaley JM, et al. The novel sodium glucose transporter 2 inhibitor dapaglifl ozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats. Diabetes Obes Metab. 2010;12:1004-12.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 1004-12
    • MacDonald, F.R.1    Peel, J.E.2    Jones, H.B.3    Mayers, R.M.4    Westgate, L.5    Whaley, J.M.6
  • 39
    • 35748952488 scopus 로고    scopus 로고
    • Phlorizin induces lipolysis and alters meal patterns in both earlyand late-lactation dairy cows
    • DOI 10.3168/jds.2006-631
    • Bradford BJ, Allen MS. Phlorizin induces lipolysis and alters meal patterns in both early-and late-lactation dairy cows. J Dairy Sci. 2007;90:1810-5. (Pubitemid 350045405)
    • (2007) Journal of Dairy Science , vol.90 , Issue.4 , pp. 1810-1815
    • Bradford, B.J.1    Allen, M.S.2
  • 41
    • 77953181310 scopus 로고    scopus 로고
    • Dapaglifl ozin treatment in patients with different stages of type 2 diabetes mellitus: Effects on glycaemic control and body weight
    • Zhang L, Feng Y, List J, Kasichayanula S, Pfi ster M. Dapaglifl ozin treatment in patients with different stages of type 2 diabetes mellitus: effects on glycaemic control and body weight. Diabetes Obes Metab. 2010;12:510-6.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 510-6
    • Zhang, L.1    Feng, Y.2    List, J.3    Kasichayanula, S.4    Pfister, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.