-
1
-
-
58249114250
-
Prevalence of CKD in the United States: a sensitivity analysis using the National Health and Nutrition Examination Survey (NHANES) 1999–2004
-
Snyder JJ, Foley RN, Collins AJ (2009) Prevalence of CKD in the United States: a sensitivity analysis using the National Health and Nutrition Examination Survey (NHANES) 1999–2004. Am J Kidney Dis 53:218–228. doi:10.1053/j.ajkd.2008.07.034
-
(2009)
Am J Kidney Dis
, vol.53
, pp. 218-228
-
-
Snyder, J.J.1
Foley, R.N.2
Collins, A.J.3
-
2
-
-
84857111725
-
The origin of interstitial myofibroblasts in chronic kidney disease
-
Grgic I, Duffield JS, Humphreys BD (2012) The origin of interstitial myofibroblasts in chronic kidney disease. Pediatr Nephrol 27:183–193. doi:10.1007/s00467-011-1772-6
-
(2012)
Pediatr Nephrol
, vol.27
, pp. 183-193
-
-
Grgic, I.1
Duffield, J.S.2
Humphreys, B.D.3
-
3
-
-
79954993703
-
Mechanisms of fibrosis: the role of the pericyte
-
Schrimpf C, Duffield JS (2011) Mechanisms of fibrosis: the role of the pericyte. Curr Opin Nephrol Hypertens 20:297–305. doi:10.1097/MNH.0b013e328344c3d4
-
(2011)
Curr Opin Nephrol Hypertens
, vol.20
, pp. 297-305
-
-
Schrimpf, C.1
Duffield, J.S.2
-
4
-
-
84867497463
-
KDOQI clinical practice guideline for diabetes and CKD: 2012 update
-
National Kidney Foundation (2012) KDOQI clinical practice guideline for diabetes and CKD: 2012 update. Am J Kidney Dis 60:850–886. doi:10.1053/j.ajkd.2012.07.005
-
(2012)
Am J Kidney Dis
, vol.60
, pp. 850-886
-
-
-
5
-
-
33847350691
-
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
-
Wynn TA (2007) Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117:524–529. doi:10.1172/JCI31487
-
(2007)
J Clin Invest
, vol.117
, pp. 524-529
-
-
Wynn, T.A.1
-
6
-
-
77955602944
-
Resolved: EMT produces fibroblasts in the kidney
-
Zeisberg M, Duffield JS (2010) Resolved: EMT produces fibroblasts in the kidney. J Am Soc Nephrol 21:1247–1253. doi:10.1681/ASN.2010060616
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1247-1253
-
-
Zeisberg, M.1
Duffield, J.S.2
-
7
-
-
0346724511
-
Epithelial–mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG (2003) Epithelial–mesenchymal transition and its implications for fibrosis. J Clin Invest 112:1776–1784. doi:10.1172/JCI20530
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
8
-
-
52049087551
-
Fibroblasts emerge via epithelial–mesenchymal transition in chronic kidney fibrosis
-
PID: 18508710, COI: 1:CAS:528:DC%2BD1cXnsVOiu74%3D
-
Zeisberg M, Kalluri R (2008) Fibroblasts emerge via epithelial–mesenchymal transition in chronic kidney fibrosis. Front Biosci 13:6991–6998
-
(2008)
Front Biosci
, vol.13
, pp. 6991-6998
-
-
Zeisberg, M.1
Kalluri, R.2
-
9
-
-
73949096744
-
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
-
This study reveals that pericytes, not epithelial cells, are the major source of scar-forming myofibroblasts in animal models of interstitial kidney disease using fate-mapping approaches
-
•• Humphreys BD, Lin S-L, Kobayashi A et al (2010) Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol 176:85–97. doi:10.2353/ajpath.2010.090517. This study reveals that pericytes, not epithelial cells, are the major source of scar-forming myofibroblasts in animal models of interstitial kidney disease using fate-mapping approaches
-
(2010)
Am J Pathol
, vol.176
, pp. 85-97
-
-
Humphreys, B.D.1
Lin, S.-L.2
Kobayashi, A.3
-
10
-
-
57149113728
-
Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
-
This study shows that pericytes and the closely related perivascular fibroblasts are the major source of scar-forming myofibroblasts in animal models of interstitial kidney disease
-
• Lin S-L, Kisseleva T, Brenner DA, Duffield JS (2008) Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol 173:1617–1627. doi:10.2353/ajpath.2008.080433. This study shows that pericytes and the closely related perivascular fibroblasts are the major source of scar-forming myofibroblasts in animal models of interstitial kidney disease
-
(2008)
Am J Pathol
, vol.173
, pp. 1617-1627
-
-
Lin, S.-L.1
Kisseleva, T.2
Brenner, D.A.3
Duffield, J.S.4
-
11
-
-
79951678325
-
Origin of new cells in the adult kidney: results from genetic labeling techniques
-
Duffield JS, Humphreys BD (2011) Origin of new cells in the adult kidney: results from genetic labeling techniques. Kidney Int 79:494–501. doi:10.1038/ki.2010.338
-
(2011)
Kidney Int
, vol.79
, pp. 494-501
-
-
Duffield, J.S.1
Humphreys, B.D.2
-
12
-
-
84862195154
-
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
-
Kisseleva T, Cong M, Paik Y et al (2012) Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci 109:9448–9453. doi:10.1073/pnas.1201840109
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 9448-9453
-
-
Kisseleva, T.1
Cong, M.2
Paik, Y.3
-
13
-
-
84655175061
-
Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
-
Bhattacharyya S, Wei J, Varga J (2011) Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nat Rev Rheumatol 8:42–54. doi:10.1038/nrrheum.2011.149
-
(2011)
Nat Rev Rheumatol
, vol.8
, pp. 42-54
-
-
Bhattacharyya, S.1
Wei, J.2
Varga, J.3
-
14
-
-
0015264624
-
Dupuytren’s contracture: fibroblast contraction? An ultrastructural study
-
PID: 5009249, COI: 1:STN:280:DyaE38%2FpsFCrsw%3D%3D
-
Gabbiani G, Gabbiani G, Majno G, Majno G (1972) Dupuytren’s contracture: fibroblast contraction? An ultrastructural study. Am J Pathol 66:131–146
-
(1972)
Am J Pathol
, vol.66
, pp. 131-146
-
-
Gabbiani, G.1
Gabbiani, G.2
Majno, G.3
Majno, G.4
-
16
-
-
0033391288
-
Far upstream regulatory elements enhance position-independent and uterus-specific expression of the murine alpha1(I) collagen promoter in transgenic mice
-
PID: 10634317, COI: 1:CAS:528:DC%2BD3cXjvFWrtQ%3D%3D
-
Krempen K, Grotkopp D, Hall K et al (1999) Far upstream regulatory elements enhance position-independent and uterus-specific expression of the murine alpha1(I) collagen promoter in transgenic mice. Gene Expr 8:151–163
-
(1999)
Gene Expr
, vol.8
, pp. 151-163
-
-
Krempen, K.1
Grotkopp, D.2
Hall, K.3
-
17
-
-
84871186965
-
Activation of pericytes: recent insights into kidney fibrosis and microvascular rarefaction
-
Fligny C, Duffield JS (2013) Activation of pericytes: recent insights into kidney fibrosis and microvascular rarefaction. Curr Opin Rheumatol 25:78–86. doi:10.1097/BOR.0b013e32835b656b
-
(2013)
Curr Opin Rheumatol
, vol.25
, pp. 78-86
-
-
Fligny, C.1
Duffield, J.S.2
-
18
-
-
81155131228
-
Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis
-
Chen Y-T, Chang F-C, Wu C-F et al (2011) Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis. Kidney Int 80:1170–1181. doi:10.1038/ki.2011.208
-
(2011)
Kidney Int
, vol.80
, pp. 1170-1181
-
-
Chen, Y.-T.1
Chang, F.-C.2
Wu, C.-F.3
-
19
-
-
84878231896
-
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis
-
Campanholle G, Ligresti G, Gharib SA, Duffield JS (2013) Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. AJP Cell Physiol 304:C591–C603. doi:10.1152/ajpcell.00414.2012
-
(2013)
AJP Cell Physiol
, vol.304
, pp. C591-C603
-
-
Campanholle, G.1
Ligresti, G.2
Gharib, S.A.3
Duffield, J.S.4
-
20
-
-
77749319814
-
Serum amyloid P inhibits fibrosis through Fc gamma R-dependent monocyte-macrophage regulation in vivo
-
Castano AP, Lin SL, Surowy T et al (2009) Serum amyloid P inhibits fibrosis through Fc gamma R-dependent monocyte-macrophage regulation in vivo. Sci Transl Med 1:5ra13–5ra13. doi:10.1126/scitranslmed.3000111
-
(2009)
Sci Transl Med
, vol.1
, pp. 5ra13
-
-
Castano, A.P.1
Lin, S.L.2
Surowy, T.3
-
21
-
-
79951816985
-
Targeting endothelium–pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
-
This study shows links between endothelium and pericytes through VEGF during kidney fibrosis and that attenuated VEGFR2 signaling is beneficial in interstitial kidney disease
-
• Lin SL, Chang FC, Schrimpf C et al (2011) Targeting endothelium–pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. AJPA 178:911–923. doi:10.1016/j.ajpath.2010.10.012. This study shows links between endothelium and pericytes through VEGF during kidney fibrosis and that attenuated VEGFR2 signaling is beneficial in interstitial kidney disease
-
(2011)
AJPA
, vol.178
, pp. 911-923
-
-
Lin, S.L.1
Chang, F.C.2
Schrimpf, C.3
-
22
-
-
77952394844
-
Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations
-
Lin SL, Castano AP, Nowlin BT et al (2009) Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations. J Immunol 183:6733–6743. doi:10.4049/jimmunol.0901473
-
(2009)
J Immunol
, vol.183
, pp. 6733-6743
-
-
Lin, S.L.1
Castano, A.P.2
Nowlin, B.T.3
-
23
-
-
80052475966
-
Migration of fibrocytes in fibrogenic liver injury
-
Scholten D, Reichart D, Paik YH et al (2011) Migration of fibrocytes in fibrogenic liver injury. Am J Pathol 179:189–198. doi:10.1016/j.ajpath.2011.03.049
-
(2011)
Am J Pathol
, vol.179
, pp. 189-198
-
-
Scholten, D.1
Reichart, D.2
Paik, Y.H.3
-
24
-
-
84855511323
-
Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
-
Rock JR, Barkauskas CE, Cronce MJ et al (2011) Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci 108:E1475–E1483. doi:10.1073/pnas.1117988108
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. E1475-E1483
-
-
Rock, J.R.1
Barkauskas, C.E.2
Cronce, M.J.3
-
25
-
-
79959809001
-
CD248+ stromal cells are associated with progressive chronic kidney disease
-
Smith SW, Eardley KS, Croft AP et al (2011) CD248+ stromal cells are associated with progressive chronic kidney disease. Kidney Int 80:199–207. doi:10.1038/ki.2011.103
-
(2011)
Kidney Int
, vol.80
, pp. 199-207
-
-
Smith, S.W.1
Eardley, K.S.2
Croft, A.P.3
-
26
-
-
84871036391
-
Kidney pericytes: a novel therapeutic target in interstitial fibrosis
-
PID: 23059881, COI: 1:CAS:528:DC%2BC3sXhsVKlug%3D%3D
-
Smith SW, Schrimpf C, Parekh DJ et al (2012) Kidney pericytes: a novel therapeutic target in interstitial fibrosis. Histol Histopathol 27:1503–1514
-
(2012)
Histol Histopathol
, vol.27
, pp. 1503-1514
-
-
Smith, S.W.1
Schrimpf, C.2
Parekh, D.J.3
-
27
-
-
84871300122
-
Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte–myofibroblast transition in obstructive kidney fibrosis
-
Wu C-F, Chiang W-C, Lai C-F et al (2012) Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte–myofibroblast transition in obstructive kidney fibrosis. Am J Pathol. doi:10.1016/j.ajpath.2012.09.009
-
(2012)
Am J Pathol
-
-
Wu, C.-F.1
Chiang, W.-C.2
Lai, C.-F.3
-
28
-
-
0035015517
-
Pericytes: cell biology and pathology
-
PID: 11340256, COI: 1:STN:280:DC%2BD3MzotlKnuw%3D%3D
-
Allt G, Lawrenson JG (2001) Pericytes: cell biology and pathology. Cells Tissues Organs 169:1–11
-
(2001)
Cells Tissues Organs
, vol.169
, pp. 1-11
-
-
Allt, G.1
Lawrenson, J.G.2
-
29
-
-
0034059140
-
Cre recombinase: the universal reagent for genome tailoring
-
PID: 10686599, COI: 1:CAS:528:DC%2BD3cXitVCjtrw%3D
-
Nagy A (2000) Cre recombinase: the universal reagent for genome tailoring. Genesis 26:99–109
-
(2000)
Genesis
, vol.26
, pp. 99-109
-
-
Nagy, A.1
-
30
-
-
78049449123
-
Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
-
Bielesz B, Sirin Y, Si H et al (2010) Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J Clin Invest 120:4040–4054. doi:10.1172/JCI43025
-
(2010)
J Clin Invest
, vol.120
, pp. 4040-4054
-
-
Bielesz, B.1
Sirin, Y.2
Si, H.3
-
31
-
-
77957252460
-
Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
-
Koesters R, Kaissling B, Lehir M et al (2010) Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol 177:632–643. doi:10.2353/ajpath.2010.091012
-
(2010)
Am J Pathol
, vol.177
, pp. 632-643
-
-
Koesters, R.1
Kaissling, B.2
Lehir, M.3
-
32
-
-
80053394522
-
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
-
Asada N, Takase M, Nakamura J et al (2011) Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest 121:3981–3990. doi:10.1172/JCI57301
-
(2011)
J Clin Invest
, vol.121
, pp. 3981-3990
-
-
Asada, N.1
Takase, M.2
Nakamura, J.3
-
33
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
PID: 10621974, COI: 1:CAS:528:DyaK1MXnsFSjtbw%3D
-
Clausen BE, Burkhardt C, Reith W et al (1999) Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res 8:265–277
-
(1999)
Transgenic Res
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
-
34
-
-
79959743981
-
Pivotal role of pericytes in kidney fibrosis
-
Kida Y, Duffield JS (2011) Pivotal role of pericytes in kidney fibrosis. Clin Exp Pharmacol Physiol 38:467–473. doi:10.1111/j.1440-1681.2011.05531.x
-
(2011)
Clin Exp Pharmacol Physiol
, vol.38
, pp. 467-473
-
-
Kida, Y.1
Duffield, J.S.2
-
35
-
-
73949086144
-
Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation
-
Stratman AN, Malotte KM, Mahan RD et al (2009) Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood 114:5091–5101. doi:10.1182/blood-2009-05-222364
-
(2009)
Blood
, vol.114
, pp. 5091-5101
-
-
Stratman, A.N.1
Malotte, K.M.2
Mahan, R.D.3
-
36
-
-
78649455280
-
Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization
-
Stratman AN, Schwindt AE, Malotte KM, Davis GE (2010) Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood 116:4720–4730. doi:10.1182/blood-2010-05-286872
-
(2010)
Blood
, vol.116
, pp. 4720-4730
-
-
Stratman, A.N.1
Schwindt, A.E.2
Malotte, K.M.3
Davis, G.E.4
-
37
-
-
79961230399
-
Pericytes: developmental, physiological, and pathological perspectives, problems, and promises
-
Armulik A, Genové G, Betsholtz C (2011) Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell 21:193–215. doi:10.1016/j.devcel.2011.07.001
-
(2011)
Dev Cell
, vol.21
, pp. 193-215
-
-
Armulik, A.1
Genové, G.2
Betsholtz, C.3
-
38
-
-
27644557532
-
The role of pericytes in blood-vessel formation and maintenance
-
Bergers G, Song S (2005) The role of pericytes in blood-vessel formation and maintenance. Neurooncology 7:452–464. doi:10.1215/S1152851705000232
-
(2005)
Neurooncology
, vol.7
, pp. 452-464
-
-
Bergers, G.1
Song, S.2
-
39
-
-
84861518893
-
The role played by perivascular cells in kidney interstitial injury
-
PID: 22551886, COI: 1:CAS:528:DC%2BC38XhtVClsr3N
-
Rojas A, Chang F-C, Lin S-L, Duffield JS (2012) The role played by perivascular cells in kidney interstitial injury. Clin Nephrol 77:400–408
-
(2012)
Clin Nephrol
, vol.77
, pp. 400-408
-
-
Rojas, A.1
Chang, F.-C.2
Lin, S.-L.3
Duffield, J.S.4
-
40
-
-
84860645452
-
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
-
Schrimpf CC, Xin CC, Campanholle GG et al (2012) Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol 23:868–883. doi:10.1681/ASN.2011080851
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 868-883
-
-
Schrimpf, C.C.1
Xin, C.C.2
Campanholle, G.G.3
-
41
-
-
0035002936
-
Pericyte regulation of renal medullary blood flow
-
PID: 11340300, COI: 1:STN:280:DC%2BD3MvmtVektA%3D%3D
-
Pallone TL, Silldorff EP (2001) Pericyte regulation of renal medullary blood flow. Exp Nephrol 9:165–170
-
(2001)
Exp Nephrol
, vol.9
, pp. 165-170
-
-
Pallone, T.L.1
Silldorff, E.P.2
-
42
-
-
0021824956
-
Microvascular pericytes contain muscle and nonmuscle actins
-
PID: 3891763, COI: 1:CAS:528:DyaL2MXks1ylur0%3D
-
Herman IM, D apos Amore PA (1985) Microvascular pericytes contain muscle and nonmuscle actins. J Cell Biol 101:43–52
-
(1985)
J Cell Biol
, vol.101
, pp. 43-52
-
-
Herman, I.M.1
D apos Amore, P.A.2
-
43
-
-
33749860102
-
Bidirectional control of CNS capillary diameter by pericytes
-
Peppiatt CM, Howarth C, Mobbs P, Attwell D (2006) Bidirectional control of CNS capillary diameter by pericytes. Nature 443:700–704. doi:10.1038/nature05193
-
(2006)
Nature
, vol.443
, pp. 700-704
-
-
Peppiatt, C.M.1
Howarth, C.2
Mobbs, P.3
Attwell, D.4
-
44
-
-
77957999327
-
Voltage-gated divalent currents in descending vasa recta pericytes
-
Zhang Z, Lin H, Cao C et al (2010) Voltage-gated divalent currents in descending vasa recta pericytes. Am J Physiol Renal Physiol 299:F862–F871. doi:10.1152/ajprenal.00321.2010
-
(2010)
Am J Physiol Renal Physiol
, vol.299
, pp. F862-F871
-
-
Zhang, Z.1
Lin, H.2
Cao, C.3
-
45
-
-
8644285052
-
Determinants of basal nitric oxide concentration in the renal medullary microcirculation
-
Zhang W, Pibulsonggram T, Edwards A (2004) Determinants of basal nitric oxide concentration in the renal medullary microcirculation. Am J Physiol Renal Physiol 287:F1189–F1203. doi:10.1152/ajprenal.00125.2004
-
(2004)
Am J Physiol Renal Physiol
, vol.287
, pp. F1189-F1203
-
-
Zhang, W.1
Pibulsonggram, T.2
Edwards, A.3
-
46
-
-
84866562683
-
Medullary thick ascending limb buffer vasoconstriction of renal outer-medullary vasa recta in salt-resistant but not salt-sensitive rats
-
O apos Connor PM, Cowley AW (2012) Medullary thick ascending limb buffer vasoconstriction of renal outer-medullary vasa recta in salt-resistant but not salt-sensitive rats. Hypertension 60:965–972. doi:10.1161/HYPERTENSIONAHA.112.195214
-
(2012)
Hypertension
, vol.60
, pp. 965-972
-
-
O apos Connor, P.M.1
Cowley, A.W.2
-
48
-
-
84864306054
-
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo
-
Proebstl D, Voisin M-B, Woodfin A et al (2012) Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med 209:1219–1234. doi:10.1084/jem.20111622
-
(2012)
J Exp Med
, vol.209
, pp. 1219-1234
-
-
Proebstl, D.1
Voisin, M.-B.2
Woodfin, A.3
-
49
-
-
84872867267
-
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1
-
This study shows the detailed signaling pathways including the dominance of non-canonical WNT pathway signaling involved in pericyte proliferation and activation
-
• Ren S, Johnson BG, Kida Y et al (2013) LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci USA 110:1440–1445. doi:10.1073/pnas.1211179110. This study shows the detailed signaling pathways including the dominance of non-canonical WNT pathway signaling involved in pericyte proliferation and activation
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1440-1445
-
-
Ren, S.1
Johnson, B.G.2
Kida, Y.3
-
50
-
-
44949200310
-
Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor
-
Basile DP, Fredrich K, Chelladurai B et al (2008) Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor. Am J Physiol Renal Physiol 294:F928–F936. doi:10.1152/ajprenal.00596.2007
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F928-F936
-
-
Basile, D.P.1
Fredrich, K.2
Chelladurai, B.3
-
51
-
-
19944429537
-
Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican
-
Jönsson-Rylander A-C, Nilsson T, Fritsche-Danielson R et al (2005) Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican. Arterioscler Thromb Vasc Biol 25:180–185. doi:10.1161/01.ATV.0000150045.27127.37
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 180-185
-
-
Jönsson-Rylander, A.-C.1
Nilsson, T.2
Fritsche-Danielson, R.3
-
52
-
-
2542473312
-
Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis
-
PID: 15153554, COI: 1:CAS:528:DC%2BD2cXktVWiuro%3D
-
Yokoi H, Mukoyama M, Nagae T et al (2004) Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J Am Soc Nephrol 15:1430–1440
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1430-1440
-
-
Yokoi, H.1
Mukoyama, M.2
Nagae, T.3
-
53
-
-
65249134946
-
Wnt/beta-catenin signaling promotes renal interstitial fibrosis
-
He W, Dai C, Li Y et al (2009) Wnt/beta-catenin signaling promotes renal interstitial fibrosis. J Am Soc Nephrol 20:765–776. doi:10.1681/ASN.2008060566
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 765-776
-
-
He, W.1
Dai, C.2
Li, Y.3
-
54
-
-
84862685208
-
Chronic VEGF blockade worsens glomerular injury in the remnant kidney model
-
Machado FG, Kuriki PS, Fujihara CK et al (2012) Chronic VEGF blockade worsens glomerular injury in the remnant kidney model. PLoS One 7:e39580. doi:10.1371/journal.pone.0039580
-
(2012)
PLoS One
, vol.7
-
-
Machado, F.G.1
Kuriki, P.S.2
Fujihara, C.K.3
-
55
-
-
40849130173
-
VEGF inhibition and renal thrombotic microangiopathy
-
Eremina V, Jefferson JA, Kowalewska J et al (2008) VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 358:1129–1136. doi:10.1056/NEJMoa0707330
-
(2008)
N Engl J Med
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
-
56
-
-
70349569570
-
EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures
-
Salvucci O, Maric D, Economopoulou M et al (2009) EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures. Blood 114:1707–1716. doi:10.1182/blood-2008-12-192294
-
(2009)
Blood
, vol.114
, pp. 1707-1716
-
-
Salvucci, O.1
Maric, D.2
Economopoulou, M.3
-
57
-
-
30344440869
-
Ephrin-B2 controls cell motility and adhesion during blood–vessel–wall assembly
-
Foo SS, Turner CJ, Adams S et al (2006) Ephrin-B2 controls cell motility and adhesion during blood–vessel–wall assembly. Cell 124:161–173. doi:10.1016/j.cell.2005.10.034
-
(2006)
Cell
, vol.124
, pp. 161-173
-
-
Foo, S.S.1
Turner, C.J.2
Adams, S.3
-
58
-
-
84875748988
-
Defective ephrinB2 reverse signaling promotes capillary rarefaction and fibrosis after kidney injury
-
Kida Y, Leronimakis N, Schrimpf C et al (2013) Defective ephrinB2 reverse signaling promotes capillary rarefaction and fibrosis after kidney injury. J Am Soc Nephrol 24(4):559–572
-
(2013)
J Am Soc Nephrol
, vol.24
, Issue.4
, pp. 559-572
-
-
Kida, Y.1
Leronimakis, N.2
Schrimpf, C.3
-
59
-
-
84859015834
-
Hedgehog-Gli pathway activation during kidney fibrosis
-
Fabian SL, Penchev RR, St-Jacques B et al (2012) Hedgehog-Gli pathway activation during kidney fibrosis. Am J Pathol 180:1441–1453. doi:10.1016/j.ajpath.2011.12.039
-
(2012)
Am J Pathol
, vol.180
, pp. 1441-1453
-
-
Fabian, S.L.1
Penchev, R.R.2
St-Jacques, B.3
-
60
-
-
84860633548
-
Sonic hedgehog signaling mediates epithelial–mesenchymal communication and promotes renal fibrosis
-
Ding H, Zhou D, Hao S et al (2012) Sonic hedgehog signaling mediates epithelial–mesenchymal communication and promotes renal fibrosis. J Am Soc Nephrol 23:801–813. doi:10.1681/ASN.2011060614
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 801-813
-
-
Ding, H.1
Zhou, D.2
Hao, S.3
-
61
-
-
0026843124
-
The activated mesangial cell: a glomerular “myofibroblast”?
-
PID: 1600136, COI: 1:STN:280:DyaK383ovVarsg%3D%3D
-
Johnson RJ, Floege J, Yoshimura A et al (1992) The activated mesangial cell: a glomerular “myofibroblast”? J Am Soc Nephrol 2:S190–S197
-
(1992)
J Am Soc Nephrol
, vol.2
, pp. S190-S197
-
-
Johnson, R.J.1
Floege, J.2
Yoshimura, A.3
-
62
-
-
84873025518
-
Podocyte biology and pathogenesis of kidney disease
-
Reiser J, Sever S (2012) Podocyte biology and pathogenesis of kidney disease. Annu Rev Med. doi:10.1146/annurev-med-050311-163340
-
(2012)
Annu Rev Med
-
-
Reiser, J.1
Sever, S.2
-
64
-
-
48149095359
-
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
-
Kobayashi A, Valerius MT, Mugford JW et al (2008) Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 3:169–181. doi:10.1016/j.stem.2008.05.020
-
(2008)
Cell Stem Cell
, vol.3
, pp. 169-181
-
-
Kobayashi, A.1
Valerius, M.T.2
Mugford, J.W.3
-
65
-
-
80052527646
-
Defining the molecular character of the developing and adult kidney podocyte
-
Brunskill EW, Georgas K, Rumballe B et al (2011) Defining the molecular character of the developing and adult kidney podocyte. PLoS One 6:e24640. doi:10.1371/journal.pone.0024640
-
(2011)
PLoS One
, vol.6
-
-
Brunskill, E.W.1
Georgas, K.2
Rumballe, B.3
|