Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis

American Journal of Pathology

Volumn 182, Issue 1, 2013, Pages 118-131

  Wu, Ching Fang ^a   Chiang, Wen Chih ^a   Lai, Chun Fu ^a   Chang, Fan Chi ^a   Chen, Yi Ting ^a   Chou, Yu Hsiang ^a   Wu, Ting Hui ^a   Linn, Geoffrey R ^b   Ling, Hong ^c   Wu, Kwan Dun ^a   Tsai, Tun Jun ^a   Chen, Yung Ming ^a   Duffield, Jeremy S ^b   Lin, Shuei Liong ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; IN VITRO STUDY; KIDNEY FIBROSIS; MOUSE; MYOFIBROBLAST; NONHUMAN; OBSTRUCTIVE KIDNEY FIBROSIS; PERICYTE; PERICYTE MYOFIBROBLAST TRANSITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; URETER OBSTRUCTION;

ANIMALS; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; KIDNEY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOFIBROBLASTS; PERICYTES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 84871300122     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.09.009     Document Type: Article

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