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Volumn 38, Issue 7, 2011, Pages 467-473

Pivotal role of pericytes in kidney fibrosis

Author keywords

Capillary rarefaction; Chronic kidney diseases; Endothelial cells; Epithelial to mesenchymal transition (EMT); Fibrosis; Kidney injury; Kidney pericytes; Myofibroblasts; Peritubular capillary

Indexed keywords

CELL ACTIVATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL INTERACTION; CELL MIGRATION; CELL STRUCTURE; CHRONIC KIDNEY DISEASE; ENDOTHELIUM CELL; GENE MAPPING; GLOMERULUS CAPILLARY; HUMAN; INTRACELLULAR SIGNALING; KIDNEY; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY INTERSTITIUM; KIDNEY TUBULE; MESANGIUM CELL; MICROVASCULARIZATION; MYOFIBROBLAST; NEPHRON; NONHUMAN; PERICYTE; REVIEW; SCAR FORMATION; STEM CELL; STROMA;

EID: 79959743981     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05531.x     Document Type: Review
Times cited : (77)

References (39)
  • 1
    • 0035015517 scopus 로고    scopus 로고
    • Pericytes. Cell biology and pathology
    • Allt G, Lawrenson JG. Pericytes. Cell biology and pathology. Cell Tissues Organs 2001; 169: 1-11.
    • (2001) Cell Tissues Organs , vol.169 , pp. 1-11
    • Allt, G.1    Lawrenson, J.G.2
  • 3
    • 0014373275 scopus 로고
    • Ultrastructure of mammalian venous capillaries, venules, and small collecting veins
    • Rhodin JA. Ultrastructure of mammalian venous capillaries, venules, and small collecting veins. J. Ultrastruct. Res. 1968; 25: 452-500.
    • (1968) J. Ultrastruct. Res. , vol.25 , pp. 452-500
    • Rhodin, J.A.1
  • 4
    • 0020965804 scopus 로고
    • Fibronectin in the microvasculature: Localization in the pericyte-endothelial interstitium
    • Courtoy PJ, Boyles J. Fibronectin in the microvasculature: Localization in the pericyte-endothelial interstitium. J. Ultrastruct. Res. 1983; 83: 258-73.
    • (1983) J. Ultrastruct. Res. , vol.83 , pp. 258-273
    • Courtoy, P.J.1    Boyles, J.2
  • 5
    • 73949086144 scopus 로고    scopus 로고
    • Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation
    • Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood 2009; 114: 5091-101.
    • (2009) Blood , vol.114 , pp. 5091-5101
    • Stratman, A.N.1    Malotte, K.M.2    Mahan, R.D.3    Davis, M.J.4    Davis, G.E.5
  • 6
    • 79951678325 scopus 로고    scopus 로고
    • Origin of new cells in the adult kidney: Results from genetic labeling techniques
    • Duffield JS, Humphreys BD. Origin of new cells in the adult kidney: Results from genetic labeling techniques. Kidney Int. 2011; 79: 494-501.
    • (2011) Kidney Int. , vol.79 , pp. 494-501
    • Duffield, J.S.1    Humphreys, B.D.2
  • 7
    • 2942671217 scopus 로고    scopus 로고
    • Role of platelet-derived growth factor in mesangium development and vasculopathies: Lessons from platelet-derived growth factor and platelet-derived growth factor receptor mutations in mice
    • Betsholtz C, Lindbolm P, Bjarnegard M, Enge M, Gerhardt H, Lindahl P. Role of platelet-derived growth factor in mesangium development and vasculopathies: Lessons from platelet-derived growth factor and platelet-derived growth factor receptor mutations in mice. Curr. Opin. Nephrol. Hypertens. 2004; 13: 45-52.
    • (2004) Curr. Opin. Nephrol. Hypertens. , vol.13 , pp. 45-52
    • Betsholtz, C.1    Lindbolm, P.2    Bjarnegard, M.3    Enge, M.4    Gerhardt, H.5    Lindahl, P.6
  • 8
    • 38349017084 scopus 로고    scopus 로고
    • Functional symbiosis between endothelium and epithelial cells in glomeruli
    • Hirschberg R, Wang S, Mitu GM. Functional symbiosis between endothelium and epithelial cells in glomeruli. Cell Tissue Res. 2008; 33: 485-93.
    • (2008) Cell Tissue Res. , vol.33 , pp. 485-493
    • Hirschberg, R.1    Wang, S.2    Mitu, G.M.3
  • 9
    • 40849130173 scopus 로고    scopus 로고
    • VEGF inhibition and renal thrombotic microangiopathy
    • Eremina V, Jefferson JA, Kowalewska J et al. VEGF inhibition and renal thrombotic microangiopathy. N. Engl. J. Med. 2008; 358: 1129-36.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1129-1136
    • Eremina, V.1    Jefferson, J.A.2    Kowalewska, J.3
  • 10
    • 48749122527 scopus 로고    scopus 로고
    • The renal cortical interstitium: Morphological and functional aspects
    • Kaissling B, Le Hir M. The renal cortical interstitium: Morphological and functional aspects. Histochem. Cell Biol. 2008; 130: 247-62.
    • (2008) Histochem. Cell Biol. , vol.130 , pp. 247-262
    • Kaissling, B.1    Le Hir, M.2
  • 11
    • 44449161800 scopus 로고    scopus 로고
    • Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat
    • Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M. Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem. Cell Biol. 2008; 130: 141-55.
    • (2008) Histochem. Cell Biol. , vol.130 , pp. 141-155
    • Picard, N.1    Baum, O.2    Vogetseder, A.3    Kaissling, B.4    Le Hir, M.5
  • 12
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
    • Lin SL, Kisseleva T, Brenner DA, Duffield JS. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am. J. Pathol. 2008; 173: 1617-27.
    • (2008) Am. J. Pathol. , vol.173 , pp. 1617-1627
    • Lin, S.L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 13
    • 79951816985 scopus 로고    scopus 로고
    • Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
    • Lin SL, Chang FC, Schrimpf C et al. Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am. J. Pathol. 2011; 178: 911-23.
    • (2011) Am. J. Pathol. , vol.178 , pp. 911-923
    • Lin, S.L.1    Chang, F.C.2    Schrimpf, C.3
  • 15
    • 0000178087 scopus 로고
    • Memoire sur le developpement, la structure et les proprietes physiologiques des capillaries sanguins et lymphatiques
    • Rouget C. Memoire sur le developpement, la structure et les proprietes physiologiques des capillaries sanguins et lymphatiques. Arch. Physiol. Norm. Pathol. 1873; 5: 603-63.
    • (1873) Arch. Physiol. Norm. Pathol. , vol.5 , pp. 603-663
    • Rouget, C.1
  • 17
    • 0021824956 scopus 로고
    • Microvascular pericytes contain muscle and nonmuscle actins
    • Herman IM, D'Amore PA. Microvascular pericytes contain muscle and nonmuscle actins. J. Cell Biol. 1985; 101: 43-52.
    • (1985) J. Cell Biol. , vol.101 , pp. 43-52
    • Herman, I.M.1    D'Amore, P.A.2
  • 18
    • 0023428761 scopus 로고
    • Immunohistochemical studies of desmin and vimentin in pericapillary cells of chicken
    • Fujimoto T, Singer SJ. Immunohistochemical studies of desmin and vimentin in pericapillary cells of chicken. J. Histochem. Cytochem. 1987; 35: 1105-15.
    • (1987) J. Histochem. Cytochem. , vol.35 , pp. 1105-1115
    • Fujimoto, T.1    Singer, S.J.2
  • 19
    • 0034331409 scopus 로고    scopus 로고
    • Ultrastructure of the capillary pericytes and the expression of smooth muscle alpha-actin and desmin in the snake infrared sensory organs
    • Nakano M, Atobe Y, Goris RC et al. Ultrastructure of the capillary pericytes and the expression of smooth muscle alpha-actin and desmin in the snake infrared sensory organs. Anat. Rec. 2000; 260: 299-307.
    • (2000) Anat. Rec. , vol.260 , pp. 299-307
    • Nakano, M.1    Atobe, Y.2    Goris, R.C.3
  • 20
    • 33749860102 scopus 로고    scopus 로고
    • Bidirectional control of CNS capillary diameter by pericytes
    • Peppiatt CM, Howarth C, Mobbs P, Attwell D. Bidirectional control of CNS capillary diameter by pericytes. Nature 2006; 443: 700-4.
    • (2006) Nature , vol.443 , pp. 700-704
    • Peppiatt, C.M.1    Howarth, C.2    Mobbs, P.3    Attwell, D.4
  • 21
    • 78649467527 scopus 로고    scopus 로고
    • Pericytes regulate the blood-brain barrier
    • Armulik A, Genové G, Mäe M et al. Pericytes regulate the blood-brain barrier. Nature 2010; 468: 557-61.
    • (2010) Nature , vol.468 , pp. 557-561
    • Armulik, A.1    Genové, G.2    Mäe, M.3
  • 22
    • 78649487239 scopus 로고    scopus 로고
    • Pericytes are required for blood-brain barrier integrity during embryogenesis
    • Daneman R, Zhou L, Kebede AA, Barres BA. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 2010; 468: 562-6.
    • (2010) Nature , vol.468 , pp. 562-566
    • Daneman, R.1    Zhou, L.2    Kebede, A.A.3    Barres, B.A.4
  • 23
    • 0037217525 scopus 로고    scopus 로고
    • Pathologic evidence of microvascular rarefaction in the brain of renal hypertensive rats
    • Suzuki K, Masawa N, Sakata N, Takatama M. Pathologic evidence of microvascular rarefaction in the brain of renal hypertensive rats. J. Stroke Cerebrovasc. Dis. 2003; 12: 8-16.
    • (2003) J. Stroke Cerebrovasc. Dis. , vol.12 , pp. 8-16
    • Suzuki, K.1    Masawa, N.2    Sakata, N.3    Takatama, M.4
  • 24
    • 12144286666 scopus 로고    scopus 로고
    • Angiopoietin-2 causes pericyte dropout in the normal retina: Evidence for involvement in diabetic retinopathy
    • Hammes HP, Lin J, Wagner P et al. Angiopoietin-2 causes pericyte dropout in the normal retina: Evidence for involvement in diabetic retinopathy. Diabetes 2004; 53: 1104-10.
    • (2004) Diabetes , vol.53 , pp. 1104-1110
    • Hammes, H.P.1    Lin, J.2    Wagner, P.3
  • 25
    • 33749542764 scopus 로고    scopus 로고
    • Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3
    • Saunders WB, Bohnsack BL, Faske JB et al. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J. Cell Biol. 2006; 175: 179-91.
    • (2006) J. Cell Biol. , vol.175 , pp. 179-191
    • Saunders, W.B.1    Bohnsack, B.L.2    Faske, J.B.3
  • 26
    • 57649135172 scopus 로고    scopus 로고
    • A role for VEGF as a negative regulator of pericyte function and vessel maturation
    • Greenberg JI, Shields DJ, Barillas SG et al. A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 2008; 456: 809-13.
    • (2008) Nature , vol.456 , pp. 809-813
    • Greenberg, J.I.1    Shields, D.J.2    Barillas, S.G.3
  • 27
    • 52649164050 scopus 로고    scopus 로고
    • Ultrastructure of islet microcirculation, pericytes and the islet exocrine interface in the HIP rat model of diabetes
    • Hayden MR, Karuparthi PR, Habibi J et al. Ultrastructure of islet microcirculation, pericytes and the islet exocrine interface in the HIP rat model of diabetes. Exp. Biol. Med. 2008; 233: 1109-23.
    • (2008) Exp. Biol. Med. , vol.233 , pp. 1109-1123
    • Hayden, M.R.1    Karuparthi, P.R.2    Habibi, J.3
  • 28
    • 61449266748 scopus 로고    scopus 로고
    • Ultrastructural descriptions of pericyte/endothelium peg-socket interdigitations in the microvasculature of human gastric carcinomas
    • Caruso RA, Fedele F, Finocchiaro G et al. Ultrastructural descriptions of pericyte/endothelium peg-socket interdigitations in the microvasculature of human gastric carcinomas. Anticancer Res. 2009; 29: 449-53.
    • (2009) Anticancer Res. , vol.29 , pp. 449-453
    • Caruso, R.A.1    Fedele, F.2    Finocchiaro, G.3
  • 29
    • 50849139576 scopus 로고    scopus 로고
    • A perivascular origin for mesenchymal stem cells in multiple human organs
    • Crisan M, Yap S, Casteilla L et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 2008; 3: 301-13.
    • (2008) Cell Stem Cell , vol.3 , pp. 301-313
    • Crisan, M.1    Yap, S.2    Casteilla, L.3
  • 30
    • 74649087130 scopus 로고    scopus 로고
    • Bone marrow derived pluripotent cells are pericytes which contribute to vascularization
    • Cai X, Lin Y, Friedrich CC et al. Bone marrow derived pluripotent cells are pericytes which contribute to vascularization. Stem Cell Rev. 2009; 5: 437-45.
    • (2009) Stem Cell Rev. , vol.5 , pp. 437-445
    • Cai, X.1    Lin, Y.2    Friedrich, C.C.3
  • 31
    • 70349569570 scopus 로고    scopus 로고
    • EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures
    • Salvucci O, Maric D, Economopoulou M et al. EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures. Blood 2009; 114: 1707-16.
    • (2009) Blood , vol.114 , pp. 1707-1716
    • Salvucci, O.1    Maric, D.2    Economopoulou, M.3
  • 32
    • 73949096744 scopus 로고    scopus 로고
    • Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
    • Humphreys BD, Lin SL, Kobayashi A et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am. J. Pathol. 2010; 176: 85-97.
    • (2010) Am. J. Pathol. , vol.176 , pp. 85-97
    • Humphreys, B.D.1    Lin, S.L.2    Kobayashi, A.3
  • 33
    • 39749172401 scopus 로고    scopus 로고
    • Intrinsic epithelial cells repair the kidney after injury
    • Humphreys BD, Valerius MT, Kobayashi A et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 2008; 2: 284-91.
    • (2008) Cell Stem Cell , vol.2 , pp. 284-291
    • Humphreys, B.D.1    Valerius, M.T.2    Kobayashi, A.3
  • 34
    • 48149095359 scopus 로고    scopus 로고
    • Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
    • Kobayashi A, Valerius MT, Mugford JW et al. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 2008; 3: 169-81.
    • (2008) Cell Stem Cell , vol.3 , pp. 169-181
    • Kobayashi, A.1    Valerius, M.T.2    Mugford, J.W.3
  • 35
    • 0036860686 scopus 로고    scopus 로고
    • Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney
    • Yu J, Carroll TJ, McMahon AP. Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development 2002; 129: 5301-12.
    • (2002) Development , vol.129 , pp. 5301-5312
    • Yu, J.1    Carroll, T.J.2    McMahon, A.P.3
  • 36
    • 77950565076 scopus 로고    scopus 로고
    • Autophagy is a component of epithelial cell fate in obstructive uropathy
    • Li L, Zepeda-Orozco D, Black R, Lin F. Autophagy is a component of epithelial cell fate in obstructive uropathy. Am. J. Pathol. 2010; 176: 1767-78.
    • (2010) Am. J. Pathol. , vol.176 , pp. 1767-1778
    • Li, L.1    Zepeda-Orozco, D.2    Black, R.3    Lin, F.4
  • 37
    • 77957252460 scopus 로고    scopus 로고
    • Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
    • Koesters R, Kaissling B, Lehir M et al. Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am. J. Pathol. 2010; 177: 632-43.
    • (2010) Am. J. Pathol. , vol.177 , pp. 632-643
    • Koesters, R.1    Kaissling, B.2    Lehir, M.3
  • 38
    • 78049449123 scopus 로고    scopus 로고
    • Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
    • Bielesz B, Sirin Y, Si H et al. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J. Clin. Invest. 2010; 120: 4040-54.
    • (2010) J. Clin. Invest. , vol.120 , pp. 4040-4054
    • Bielesz, B.1    Sirin, Y.2    Si, H.3
  • 39
    • 79959754392 scopus 로고    scopus 로고
    • Exploring the origin of the cells responsible for regeneration and fibrosis in the kidneys
    • F-FC163 (Abstract.
    • Endo T, Okuda T, Nakamura J et al. Exploring the origin of the cells responsible for regeneration and fibrosis in the kidneys. J. Am. Soc. Nephrol. 2010; 21: F-FC163 (Abstract).
    • (2010) J. Am. Soc. Nephrol. , vol.21
    • Endo, T.1    Okuda, T.2    Nakamura, J.3


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