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Volumn 27, Issue 2, 2012, Pages 183-193

The origin of interstitial myofibroblasts in chronic kidney disease

Author keywords

Chronic kidney disease; EMT; Fibrosis; Genetic fate mapping; Myofibroblast

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALVASCULIN; CRE RECOMBINASE; GAMMA GLUTAMYLTRANSFERASE; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN;

EID: 84857111725     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-011-1772-6     Document Type: Review
Times cited : (176)

References (66)
  • 1
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • DOI 10.1172/JCI31487
    • Wynn TA (2007) Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117:524-529 (Pubitemid 46348506)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 524-529
    • Wynn, T.A.1
  • 2
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • DOI 10.1002/path.2277
    • Wynn TA (2008) Cellular and molecular mechanisms of fibrosis. J Pathol 214:199-210 (Pubitemid 351160157)
    • (2008) Journal of Pathology , vol.214 , Issue.2 , pp. 199-210
    • Wynn, T.A.1
  • 3
    • 0028334128 scopus 로고
    • On the pathogenesis of chronic renal failure in primary glomerulopathies: A view from the interstitium
    • Bohle A, Strutz F, Muller GA (1994) On the pathogenesis of chronic renal failure in primary glomerulopathies: A view from the interstitium. Exp Nephrol 2:205-210 (Pubitemid 24201686)
    • (1994) Experimental Nephrology , vol.2 , Issue.4 , pp. 205-210
    • Bohle, A.1    Strutz, F.2    Muller, G.A.3
  • 6
    • 0022881517 scopus 로고
    • A monoclonal antibody against α-smooth muscle actin: A new probe for smooth muscle differentiation
    • DOI 10.1083/jcb.103.6.2787
    • Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G (1986) A monoclonal antibody against alpha-smooth muscle actin: A new probe for smooth muscle differentiation. J Cell Biol 103:2787-2796 (Pubitemid 17008024)
    • (1986) Journal of Cell Biology , vol.103 , Issue.6 , pp. 2787-2796
    • Skalli, O.1    Ropraz, P.2    Trzeciak, A.3
  • 7
    • 0033178473 scopus 로고    scopus 로고
    • Mechanisms of myofibroblast activity and phenotypic modulation
    • DOI 10.1006/excr.1999.4543
    • Serini G, Gabbiani G (1999) Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 250:273-283 (Pubitemid 29367440)
    • (1999) Experimental Cell Research , vol.250 , Issue.2 , pp. 273-283
    • Serini, G.1    Gabbiani, G.2
  • 9
    • 0025306468 scopus 로고
    • α-Smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing
    • Darby I, Skalli O, Gabbiani G (1990) Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest 63:21-29 (Pubitemid 20234670)
    • (1990) Laboratory Investigation , vol.63 , Issue.1 , pp. 21-29
    • Darby, I.1    Skalli, O.2    Gabbiani, G.3
  • 10
    • 0027212686 scopus 로고
    • Transforming growth factor-β1 induces α-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G (1993) Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122:103-111 (Pubitemid 23188802)
    • (1993) Journal of Cell Biology , vol.122 , Issue.1 , pp. 103-111
    • Desmouliere, A.1    Geinoz, A.2    Gabbiani, F.3    Gabbiani, G.4
  • 11
    • 0031828004 scopus 로고    scopus 로고
    • The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-β1
    • DOI 10.1083/jcb.142.3.873
    • Serini G, Bochaton-Piallat ML, Ropraz P, Geinoz A, Borsi L, Zardi L, Gabbiani G (1998) The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol 142:873-881 (Pubitemid 28381502)
    • (1998) Journal of Cell Biology , vol.142 , Issue.3 , pp. 873-881
    • Serini, G.1    Bochaton-Piallat, M.-L.2    Ropraz, P.3    Geinoz, A.4    Borsi, L.5    Zardi, L.6    Gabbiani, G.7
  • 13
    • 84918732190 scopus 로고
    • Ueber entzuendung und eiterung
    • Cohnheim J (1867) Ueber Entzuendung und Eiterung. Virchows Arch 40:1-79
    • (1867) Virchows Arch , vol.40 , pp. 1-79
    • Cohnheim, J.1
  • 14
    • 0014747850 scopus 로고
    • Wound healing and collagen formation. VI. The origin of the wound fibroblast studied in parabiosis
    • Ross R, Everett NB, Tyler R (1970) Wound healing and collagen formation. VI. The origin of the wound fibroblast studied in parabiosis. J Cell Biol 44:645-654
    • (1970) J Cell Biol , vol.44 , pp. 645-654
    • Ross, R.1    Everett, N.B.2    Tyler, R.3
  • 15
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • DOI 10.1172/JCI200320530
    • Kalluri R, Neilson EG (2003) Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112:1776-1784 (Pubitemid 38063698)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 16
    • 77949351029 scopus 로고    scopus 로고
    • New insights into epithelial-mesenchymal transition in kidney fibrosis
    • Liu Y (2010) New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 21:212-222
    • (2010) J Am Soc Nephrol , vol.21 , pp. 212-222
    • Liu, Y.1
  • 17
    • 0020358296 scopus 로고
    • Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells
    • DOI 10.1083/jcb.95.1.333
    • Greenburg G, Hay ED (1982) Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells. J Cell Biol 95:333-339 (Pubitemid 13197104)
    • (1982) Journal of Cell Biology , vol.95 , Issue.1 , pp. 333-339
    • Greenburg, G.1    Hay, E.D.2
  • 18
    • 70450198396 scopus 로고    scopus 로고
    • Epithelialmesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelialmesenchymal transitions in development and disease. Cell 139:871-890
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 19
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
    • Yang J, Weinberg RA (2008) Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis. Dev Cell 14:818-829 (Pubitemid 351757205)
    • (2008) Developmental Cell , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 20
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelialmesenchymal transition
    • Kalluri R, Weinberg RA (2009) The basics of epithelialmesenchymal transition. J Clin Invest 119:1420-1428
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 21
    • 0347993932 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance, molecular mechanism, and therapeutic intervention
    • DOI 10.1097/01.ASN.0000106015.29070.E7
    • Liu Y (2004) Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol 15:1-12 (Pubitemid 38020692)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.1 , pp. 1-12
    • Liu, Y.1
  • 23
    • 0028273536 scopus 로고
    • Localization of proliferating cell nuclear antigen, vimentin, c- Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells
    • Witzgall R, Brown D, Schwarz C, Bonventre JV (1994) Localization of proliferating cell nuclear antigen, vimentin, c- Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 93:2175-2188
    • (1994) J Clin Invest , vol.93 , pp. 2175-2188
    • Witzgall, R.1    Brown, D.2    Schwarz, C.3    Bonventre, J.V.4
  • 24
    • 0023618920 scopus 로고
    • Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney
    • Grone HJ, Weber K, Grone E, Helmchen U, Osborn M (1987) Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney. Am J Pathol 129:1
    • (1987) Am J Pathol , vol.129 , pp. 1
    • Grone, H.J.1    Weber, K.2    Grone, E.3    Helmchen, U.4    Osborn, M.5
  • 25
    • 21544440606 scopus 로고    scopus 로고
    • Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys
    • DOI 10.1007/s00418-005-0788-z
    • Le Hir M, Hegyi I, Cueni-Loffing D, Loffing J, Kaissling B (2005) Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys. Histochem Cell Biol 123:335-346 (Pubitemid 40922217)
    • (2005) Histochemistry and Cell Biology , vol.123 , Issue.4-5 , pp. 335-346
    • Le Hir, M.1    Hegyi, I.2    Cueni-Loffing, D.3    Loffing, J.4    Kaissling, B.5
  • 26
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagenproducing cells in obstructive fibrosis of the kidney
    • Lin SL, Kisseleva T, Brenner DA, Duffield JS (2008) Pericytes and perivascular fibroblasts are the primary source of collagenproducing cells in obstructive fibrosis of the kidney. Am J Pathol 173:1617-1627
    • (2008) Am J Pathol , vol.173 , pp. 1617-1627
    • Lin, S.L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 27
    • 77950565076 scopus 로고    scopus 로고
    • Autophagy is a component of epithelial cell fate in obstructive uropathy
    • Li L, Zepeda-Orozco D, Black R, Lin F (2010) Autophagy is a component of epithelial cell fate in obstructive uropathy. Am J Pathol 176:1767-1778
    • (2010) Am J Pathol , vol.176 , pp. 1767-1778
    • Li, L.1    Zepeda-Orozco, D.2    Black, R.3    Lin, F.4
  • 28
    • 33748328362 scopus 로고    scopus 로고
    • Genetic inducible fate mapping in mouse: Establishing genetic lineages and defining genetic neuroanatomy in the nervous system
    • DOI 10.1002/dvdy.20884
    • Joyner AL, Zervas M (2006) Genetic inducible fate mapping in mouse: Establishing genetic lineages and defining genetic neuroanatomy in the nervous system. Dev Dyn 235:2376-2385 (Pubitemid 44325253)
    • (2006) Developmental Dynamics , vol.235 , Issue.9 , pp. 2376-2385
    • Joyner, A.L.1    Zervas, M.2
  • 29
    • 79951678325 scopus 로고    scopus 로고
    • Origin of new cells in the adult kidney: Results from genetic labeling techniques
    • doi:10.1038/ki.2010.338
    • Duffield JS, Humphreys BD (2010) Origin of new cells in the adult kidney: Results from genetic labeling techniques. Kidney Int. doi:10.1038/ki.2010.338
    • (2010) Kidney Int.
    • Duffield, J.S.1    Humphreys, B.D.2
  • 30
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: A tool for temporally regulated gene activation/inactivation in the mouse
    • DOI 10.1006/dbio.2002.0597
    • Hayashi S, McMahon AP (2002) Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: A tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 244:305-318 (Pubitemid 34450645)
    • (2002) Developmental Biology , vol.244 , Issue.2 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 40
    • 1942517003 scopus 로고    scopus 로고
    • Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
    • DOI 10.1038/nature02460
    • Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC (2004) Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 428:668-673 (Pubitemid 38524811)
    • (2004) Nature , vol.428 , Issue.6983 , pp. 668-673
    • Balsam, L.B.1    Wagers, A.J.2    Christensen, J.L.3    Kofidis, T.4    Weissmann, I.L.5    Robbins, R.C.6
  • 41
    • 77955602944 scopus 로고    scopus 로고
    • Resolved: EMT produces fibroblasts in the kidney
    • Zeisberg M, Duffield JS (2010) Resolved: EMT produces fibroblasts in the kidney. J Am Soc Nephrol 21:1247-1253
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1247-1253
    • Zeisberg, M.1    Duffield, J.S.2
  • 42
    • 73949148649 scopus 로고    scopus 로고
    • The origin of renal fibroblasts and progression of kidney disease
    • Cook HT (2010) The origin of renal fibroblasts and progression of kidney disease. Am J Pathol 176:22-24
    • (2010) Am J Pathol , vol.176 , pp. 22-24
    • Cook, H.T.1
  • 43
    • 0027258497 scopus 로고
    • Vascular adventitial cell expression of collagen I messenger ribonucleic acid in anti-glomerular basement membrane antibody-induced crescentic nephritis in the rabbit: A cellular source for interstitial collagen synthesis in inflammatory renal disease
    • Wiggins R, Goyal M, Merritt S, Killen PD (1993) Vascular adventitial cell expression of collagen I messenger ribonucleic acid in anti-glomerular basement membrane antibody-induced crescentic nephritis in the rabbit. A cellular source for interstitial collagen synthesis in inflammatory renal disease. Lab Invest 68:557-565 (Pubitemid 23171855)
    • (1993) Laboratory Investigation , vol.68 , Issue.5 , pp. 557-565
    • Wiggins, R.1    Goyal, M.2    Merritt, S.3    Killen, P.D.4
  • 44
    • 27544515448 scopus 로고    scopus 로고
    • Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis
    • Faulkner JL, Szcykalski LM, Springer F, Barnes JL (2005) Origin of interstitial fibroblasts in an accelerated model of angiotensin IIinduced renal fibrosis. Am J Pathol 167:1193-1205 (Pubitemid 41541407)
    • (2005) American Journal of Pathology , vol.167 , Issue.5 , pp. 1193-1205
    • Faulkner, J.L.1    Szcykalski, L.M.2    Springer, F.3    Barnes, J.L.4
  • 45
    • 44449161800 scopus 로고    scopus 로고
    • Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat
    • Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M (2008) Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem Cell Biol 130:141-155
    • (2008) Histochem Cell Biol , vol.130 , pp. 141-155
    • Picard, N.1    Baum, O.2    Vogetseder, A.3    Kaissling, B.4    Le Hir, M.5
  • 46
    • 84857121695 scopus 로고    scopus 로고
    • Cells involved in renal tubulointerstitial degeneration and fibrosis-A matter of differentiation or cell lineage switch? ISN nexus Fibrosis and the Kidney
    • Geneva, Switzerland.
    • Grone HJ, Kriz W (2010) Cells involved in renal tubulointerstitial degeneration and fibrosis-A matter of differentiation or cell lineage switch? ISN nexus Fibrosis and the Kidney. International Society of Nephrology, Geneva, Switzerland.
    • (2010) International Society of Nephrology
    • Grone, H.J.1    Kriz, W.2
  • 48
    • 77956169218 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in injury of solid organs: Fact or artifact?
    • Duffield JS (2010) Epithelial to mesenchymal transition in injury of solid organs: Fact or artifact? Gastroenterology 139(4):1081-1083
    • (2010) Gastroenterology , vol.139 , Issue.4 , pp. 1081-1083
    • Duffield, J.S.1
  • 50
    • 77950612565 scopus 로고    scopus 로고
    • The epithelial-to-mesenchymal transition in liver fibrosis: Here today, gone tomorrow?
    • Wells RG (2010) The epithelial-to-mesenchymal transition in liver fibrosis: Here today, gone tomorrow? Hepatology 51:737-740
    • (2010) Hepatology , vol.51 , pp. 737-740
    • Wells, R.G.1
  • 51
    • 34547419062 scopus 로고    scopus 로고
    • Fibrocytes: A new insight into kidney fibrosis
    • DOI 10.1038/sj.ki.5002325, PII 5002325
    • Wada T, Sakai N, Matsushima K, Kaneko S (2007) Fibrocytes: A new insight into kidney fibrosis. Kidney Int 72:269-273 (Pubitemid 47172378)
    • (2007) Kidney International , vol.72 , Issue.3 , pp. 269-273
    • Wada, T.1    Sakai, N.2    Matsushima, K.3    Kaneko, S.4
  • 56
    • 14044279905 scopus 로고    scopus 로고
    • Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development
    • DOI 10.1242/dev.01604
    • Levinson RS, Batourina E, Choi C, Vorontchikhina M, Kitajewski J, Mendelsohn CL (2005) Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development. Development 132:529-539 (Pubitemid 40277693)
    • (2005) Development , vol.132 , Issue.3 , pp. 529-539
    • Levinson, R.S.1    Batourina, E.2    Choi, C.3    Vorontchikhina, M.4    Kitajewski, J.5    Mendelsohn, C.L.6
  • 57
    • 0029741093 scopus 로고    scopus 로고
    • Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2
    • Hatini V, Huh SO, Herzlinger D, Soares VC, Lai E (1996) Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. Genes Dev 10:1467-1478 (Pubitemid 26260704)
    • (1996) Genes and Development , vol.10 , Issue.12 , pp. 1467-1478
    • Hatini, V.1    Huh, S.O.2    Herzlinger, D.3    Soares, V.C.4    Lai, E.5
  • 58
    • 0000178087 scopus 로고
    • Memoire sur le developpement, la structure et les proprietes physiologiques des capillaires sanguins et lymphatiques
    • Rouget C (1873) Memoire sur le developpement, la structure et les proprietes physiologiques des capillaires sanguins et lymphatiques. Arch Physiol Norm et Path 5:603-663
    • (1873) Arch Physiol Norm et Path , vol.5 , pp. 603-663
    • Rouget, C.1
  • 59
    • 0020965804 scopus 로고
    • Fibronectin in the microvasculature: Localization in the pericyte-endothelial interstitium
    • DOI 10.1016/S0022-5320(83)90133-8
    • Courtnoy P, Boyles J (1983) Fibronectin in the microvasculature: Localization in the pericyte-endothelial interstitium. J Ultrastruct Res 83:258-273 (Pubitemid 13003901)
    • (1983) Journal of Ultrastructure Research , vol.83 , Issue.3 , pp. 258-273
    • Courtoy, P.J.1    Boyles, J.2
  • 60
    • 0029963991 scopus 로고    scopus 로고
    • Morphology of interstitial cells in the healthy kidney
    • Kaissling B, Hegyi I, Loffing J, Le Hir M (1996) Morphology of interstitial cells in the healthy kidney. Anat Embryol (Berl) 193:303-318 (Pubitemid 26107763)
    • (1996) Anatomy and Embryology , vol.193 , Issue.4 , pp. 303-318
    • Kaissling, B.1
  • 62
    • 0025778643 scopus 로고
    • Heterogeneity of microvascular pericytes for smooth muscle type alpha-actin
    • Nehls V, Drenckhahn D (1991) Heterogeneity of microvascular pericytes for smoothmuscle type alpha-actin. J Cell Biol 113:147-154 (Pubitemid 21909681)
    • (1991) Journal of Cell Biology , vol.113 , Issue.1 , pp. 147-154
    • Nehls, V.1    Drenckhahn, D.2
  • 63
    • 0028890174 scopus 로고
    • The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells
    • Ronnov-Jessen L, Petersen OW, Koteliansky VE, Bissell MJ (1995) The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells. J Clin Invest 95:859-873
    • (1995) J Clin Invest , vol.95 , pp. 859-873
    • Ronnov-Jessen, L.1    Petersen, O.W.2    Koteliansky, V.E.3    Bissell, M.J.4
  • 66
    • 77952174830 scopus 로고    scopus 로고
    • Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
    • 531p following 143
    • Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV (2010) Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med 16:535-543, 531p following 143
    • (2010) Nat Med , vol.16 , pp. 535-543
    • Yang, L.1    Besschetnova, T.Y.2    Brooks, C.R.3    Shah, J.V.4    Bonventre, J.V.5


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