메뉴 건너뛰기




Volumn 25, Issue 1, 2013, Pages 78-86

Activation of pericytes: Recent insights into kidney fibrosis and microvascular rarefaction

Author keywords

Chronic disease; fibrosis; microvasculature; pericytes

Indexed keywords

CELL ACTIVATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL INTERACTION; FIBROBLAST; FIBROGENESIS; HUMAN; KIDNEY FIBROSIS; MICROVASCULATURE; MYOFIBROBLAST; NONHUMAN; PATHOPHYSIOLOGY; PERICYTE; PRIORITY JOURNAL; REVIEW;

EID: 84871186965     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32835b656b     Document Type: Review
Times cited : (43)

References (46)
  • 1
    • 84855995604 scopus 로고    scopus 로고
    • Endothelial cell-pericyte interactions stimulate base-ment membrane matrix assembly: Influence on vascular tube remodeling, maturation, and stabilization
    • Stratman AN, Davis GE. Endothelial cell-pericyte interactions stimulate base-ment membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc Microanal 2012; 18:68-80.
    • (2012) Microsc Microanal , vol.18 , pp. 68-80
    • Stratman, A.N.1    Davis, G.E.2
  • 2
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011; 473:298-307.
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 3
    • 80052933197 scopus 로고    scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell 2011; 146:873-887.
    • (2011) Cell , vol.146 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 5
    • 0014373275 scopus 로고
    • Ultrastructure of mammalian venous capillaries, venules, and small collecting veins
    • Rhodin JA. Ultrastructure of mammalian venous capillaries, venules, and small collecting veins. J Ultrastruct Res 1968; 25:452-500.
    • (1968) J Ultrastruct Res , vol.25 , pp. 452-500
    • Rhodin, J.A.1
  • 6
    • 50849139576 scopus 로고    scopus 로고
    • Aperivascularorigin for mesenchymal stem cells in multiple human organs
    • Crisan M, Yap S, Casteilla L, et al. Aperivascularorigin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 2008; 3:301-313.
    • (2008) Cell Stem Cell , vol.3 , pp. 301-313
    • Crisan, M.1    Yap, S.2    Casteilla, L.3
  • 7
    • 68849128539 scopus 로고    scopus 로고
    • Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche
    • Díaz-Flores L, Gutiérrez R, Madrid JF, et al. Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche. Histol Histopathol 2009; 24:909-969.
    • (2009) Histol Histopathol , vol.24 , pp. 909-969
    • Díaz-Flores, L.1    Gutiérrez, R.2    Madrid, J.F.3
  • 8
    • 73949086144 scopus 로고    scopus 로고
    • Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation
    • Stratman AN, Malotte KM, Mahan RD, et al. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood 2009; 114:5091-5101.
    • (2009) Blood , vol.114 , pp. 5091-5101
    • Stratman, A.N.1    Malotte, K.M.2    Mahan, R.D.3
  • 9
    • 78649455280 scopus 로고    scopus 로고
    • Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization
    • Stratman AN, Schwindt AE, Malotte KM, Davis GE. Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood 2010; 116:4720-4730.
    • (2010) Blood , vol.116 , pp. 4720-4730
    • Stratman, A.N.1    Schwindt, A.E.2    Malotte, K.M.3    Davis, G.E.4
  • 12
    • 73949096744 scopus 로고    scopus 로고
    • Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
    • Humphreys BD, Lin S-L, Kobayashi A, et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol 2010; 176:85-97.
    • (2010) Am J Pathol , vol.176 , pp. 85-97
    • Humphreys, B.D.1    Lin, S.-L.2    Kobayashi, A.3
  • 13
    • 79961230399 scopus 로고    scopus 로고
    • Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
    • Armulik A, Genové G, Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell 2011; 21:193-215.
    • (2011) Dev Cell , vol.21 , pp. 193-215
    • Armulik, A.1    Genové, G.2    Betsholtz, C.3
  • 15
    • 82355190219 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of renal fibrosis
    • Liu Y. Cellular and molecular mechanisms of renal fibrosis. Nat Rev Nephrol 2011; 7:684-696.
    • (2011) Nat Rev Nephrol , vol.7 , pp. 684-696
    • Liu, Y.1
  • 16
    • 84866153571 scopus 로고    scopus 로고
    • Signaling required for blood vessel maintenance: Molecular basis and pathological manifestations
    • Murakami M. Signaling required for blood vessel maintenance: molecular basis and pathological manifestations. Int J Vasc Med 2012; 2012:293641.
    • (2012) Int J Vasc Med , vol.2012 , pp. 293641
    • Murakami, M.1
  • 17
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol 2008; 214:199-210.
    • (2008) J Pathol , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 19
    • 57149094066 scopus 로고    scopus 로고
    • How many differentroads mayacell walkdown in orderto becomea fibroblast?
    • Strutz F. How many differentroads mayacell walkdown in orderto becomea fibroblast? J Am Soc Nephrol 2008; 19:2246-2248.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2246-2248
    • Strutz, F.1
  • 20
    • 77955602944 scopus 로고    scopus 로고
    • Resolved: EMT produces fibroblasts in the kidney
    • Zeisberg M, Duffield JS. Resolved: EMT produces fibroblasts in the kidney. J Am Soc Nephrol 2010; 21:1247-1253.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1247-1253
    • Zeisberg, M.1    Duffield, J.S.2
  • 21
    • 79955120145 scopus 로고    scopus 로고
    • Is it the end of the line for the EMT?
    • Kisseleva T, Brenner DA. Is it the end of the line for the EMT? Hepatology 2011; 53:1433-1435.
    • (2011) Hepatology , vol.53 , pp. 1433-1435
    • Kisseleva, T.1    Brenner, D.A.2
  • 22
    • 79551521517 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) in kidney fibrosis: Fact or fantasy?
    • Kriz W, Kaissling B, Le Hir M. Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy? J Clin Invest 2011; 121:468-474.
    • (2011) J Clin Invest , vol.121 , pp. 468-474
    • Kriz, W.1    Kaissling, B.2    Le Hir, M.3
  • 23
    • 79958779687 scopus 로고    scopus 로고
    • Scar wars: Mapping the fate of epithelial-mesench-ymal-myofibroblast transition
    • Quaggin SE, Kapus A. Scar wars: mapping the fate of epithelial-mesench- ymal-myofibroblast transition. Kidney Int 2011; 80:41-50.
    • (2011) Kidney Int , vol.80 , pp. 41-50
    • Quaggin, S.E.1    Kapus, A.2
  • 24
    • 84856976151 scopus 로고    scopus 로고
    • What'snewin liver fibrosis-The origin of myofibroblasts in liverfibrosis
    • Iwaisako K, Brenner DA, Kisseleva T. What'snewin liver fibrosis-The origin of myofibroblasts in liverfibrosis. J Gastroenterol Hepatol 2012; 27 (Suppl 2): 65-68.
    • (2012) J Gastroenterol Hepatol , vol.27 , Issue.SUPPL. 2 , pp. 65-68
    • Iwaisako, K.1    Brenner, D.A.2    Kisseleva, T.3
  • 25
    • 78649467527 scopus 로고    scopus 로고
    • Pericytes regulate the blood-brain barrier
    • Armulik A, Genové G, Mäe M, et al. Pericytes regulate the blood-brain barrier. Nature 2010; 468:557-561.
    • (2010) Nature , vol.468 , pp. 557-561
    • Armulik, A.1    Genové, G.2    Mäe, M.3
  • 26
    • 79960099283 scopus 로고    scopus 로고
    • A pericyteorigin of spinal cord scartissue
    • Göritz C, Dias DO, Tomilin N, et al. A pericyteorigin of spinal cord scartissue. Science 2011; 333:238-242.
    • (2011) Science , vol.333 , pp. 238-242
    • Göritz, C.1    Dias, D.O.2    Tomilin, N.3
  • 27
    • 84855511323 scopus 로고    scopus 로고
    • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesench-ymal transition
    • Rock JR, Barkauskas CE, Cronce MJ, et al. Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesench-ymal transition. Proc Natl Acad Sci USA 2011; 108:E1475-E1483.
    • (2011) Proc Natl Acad Sci USA , vol.108
    • Rock, J.R.1    Barkauskas, C.E.2    Cronce, M.J.3
  • 28
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
    • Lin S-L, Kisseleva T, Brenner DA, Duffield JS. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol 2008; 173:1617-1627.
    • (2008) Am J Pathol , vol.173 , pp. 1617-1627
    • Lin, S.-L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 29
    • 84861518893 scopus 로고    scopus 로고
    • Therole played by perivascularcells in kidney interstitial injury
    • Rojas A, Chang FC, Lin SL, Duffield JS. Therole played by perivascularcells in kidney interstitial injury. Clin Nephrol 2012; 77:400-408.
    • (2012) Clin Nephrol , vol.77 , pp. 400-408
    • Rojas, A.1    Chang, F.C.2    Lin, S.L.3    Duffield, J.S.4
  • 30
    • 78049449123 scopus 로고    scopus 로고
    • Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
    • Bielesz B, Sirin Y, Si H, et al. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J Clin Invest 2010; 120:4040-4054.
    • (2010) J Clin Invest , vol.120 , pp. 4040-4054
    • Bielesz, B.1    Sirin, Y.2    Si, H.3
  • 31
    • 77957252460 scopus 로고    scopus 로고
    • Tubularoverexpression oftransforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
    • Koesters R, Kaissling B, Lehir M, et al. Tubularoverexpression oftransforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol 2010; 177:632-643.
    • (2010) Am J Pathol , vol.177 , pp. 632-643
    • Koesters, R.1    Kaissling, B.2    Lehir, M.3
  • 32
    • 77950565076 scopus 로고    scopus 로고
    • Autophagy is a component of epithelial cell fate in obstructive uropathy
    • Li L, Zepeda-Orozco D, Black R, Lin F. Autophagy is a component of epithelial cell fate in obstructive uropathy. Am J Pathol 2010; 1 76:1 767-1778.
    • (2010) Am J Pathol , vol.176 , pp. 1767-1778
    • Li, L.1    Zepeda-Orozco, D.2    Black, R.3    Lin, F.4
  • 33
    • 0025734994 scopus 로고
    • Perisinusoidal stellatecellsof the liver: Important roles in retinol metabolism and fibrosis
    • Blomhoff R, Wake K. Perisinusoidal stellatecellsof the liver: important roles in retinol metabolism and fibrosis. FASEB J 1991; 5:271-277.
    • (1991) FASEB J , vol.5 , pp. 271-277
    • Blomhoff, R.1    Wake, K.2
  • 34
    • 0029011135 scopus 로고
    • Hepatic stellate (ITO) cells: Expanding roles for a liver-specific pericyte
    • Pinzani M. Hepatic stellate (ITO) cells: expanding roles for a liver-specific pericyte. J Hepatol 1995; 22:700-706.
    • (1995) J Hepatol , vol.22 , pp. 700-706
    • Pinzani, M.1
  • 35
    • 79951900204 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interactions in biliary diseases
    • Fabris L, Strazzabosco M. Epithelial-mesenchymal interactions in biliary diseases. Semin Liver Dis 2011;31:11-32.
    • (2011) Semin Liver Dis , vol.31 , pp. 11-32
    • Fabris, L.1    Strazzabosco, M.2
  • 36
    • 84862195154 scopus 로고    scopus 로고
    • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
    • Kisseleva T, Cong M, Paik Y, et al. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci USA 2012; 109:9448-9453.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 9448-9453
    • Kisseleva, T.1    Cong, M.2    Paik, Y.3
  • 37
    • 84655175061 scopus 로고    scopus 로고
    • Understanding fibrosis in systemic sclerosis: Shifting paradigms, emerging opportunities
    • Bhattacharyya S, Wei J, Varga J. Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nat Rev Rheumatol 2012; 8:42-54.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 42-54
    • Bhattacharyya, S.1    Wei, J.2    Varga, J.3
  • 38
    • 79955955054 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in renal fibrosis: Evidenceforand against
    • Fragiadaki M, Mason RM. Epithelial-mesenchymal transition in renal fibrosis: evidenceforand against. Int J Exp Pathol 2011; 92:143-150.
    • (2011) Int J Exp Pathol , vol.92 , pp. 143-150
    • Fragiadaki, M.1    Mason, R.M.2
  • 39
    • 79951678325 scopus 로고    scopus 로고
    • Origin of new cells in the adult kidney: Results from genetic labeling techniques
    • Duffield JS, Humphreys BD. Origin of new cells in the adult kidney: results from genetic labeling techniques. Kidney Int 2011; 79:494-501.
    • (2011) Kidney Int , vol.79 , pp. 494-501
    • Duffield, J.S.1    Humphreys, B.D.2
  • 40
    • 79951816985 scopus 로고    scopus 로고
    • Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
    • Lin S-L, Chang F-C, Schrimpf C, et al. Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am J Pathol 2011; 178:911-923.
    • (2011) Am J Pathol , vol.178 , pp. 911-923
    • Lin, S.-L.1    Chang, F.-C.2    Schrimpf, C.3
  • 41
    • 79953886254 scopus 로고    scopus 로고
    • Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease
    • Mayer G. Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease. Nephrol Dial Transplant 2011; 26:1132-1137.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 1132-1137
    • Mayer, G.1
  • 42
    • 79953196750 scopus 로고    scopus 로고
    • Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury
    • Basile DP, Friedrich JL, Spahic J, et al. Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury. Am J Physiol Renal Physiol 2011; 300:F721-F733.
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Basile, D.P.1    Friedrich, J.L.2    Spahic, J.3
  • 43
    • 84867378238 scopus 로고    scopus 로고
    • Low Proliferative Potential and Impaired Angiogenesis of Cultured Rat Kidney Endothelial Cells [Internet]
    • New York N. Y.: 1994) doi: 10. 1111/j.1549.8719.2012.00193 x
    • Basile DP, Zeng P, Friedrich JL, et al. Low proliferative potential and impaired angiogenesis of cultured rat kidney endothelial cells [Internet]. Microcircula-tion (New York, N. Y.: 1994) 2012/doi: 10. 1111/j. 1549-8719. 2012. 00193. x.
    • (2012) Microcircula-tion
    • Basile, D.P.1    Zeng, P.2    Friedrich, J.L.3
  • 44
    • 84860645452 scopus 로고    scopus 로고
    • Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
    • Schrimpf C, Xin C, Campanholle G, et al. Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol 2012; 23:868-883.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 868-883
    • Schrimpf, C.1    Xin, C.2    Campanholle, G.3
  • 45
    • 84860640533 scopus 로고    scopus 로고
    • Activated pericytes and the inhibition of renal vascular stability: Obstacles for kidney repair
    • Basile DP, Sutton TA. Activated pericytes and the inhibition of renal vascular stability: obstacles for kidney repair. J Am Soc Nephrol 2012; 23:767-769.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 767-769
    • Basile, D.P.1    Sutton, T.A.2
  • 46
    • 84858998542 scopus 로고    scopus 로고
    • Restoring the renal microvasculature to treat chronic kidney disease
    • Long DA, Norman JT, Fine LG. Restoring the renal microvasculature to treat chronic kidney disease. Nat Rev Nephrol 2012; 8:244-250.
    • (2012) Nat Rev Nephrol , vol.8 , pp. 244-250
    • Long, D.A.1    Norman, J.T.2    Fine, L.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.