Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration

EMBO Molecular Medicine

Volumn 8, Issue 10, 2016, Pages 1197-1211

  Orellana, Daniel I ^a   Santambrogio, Paolo ^a   Rubio, Alicia ^a   Yekhlef, Latefa ^a   Cancellieri, Cinzia ^a   Dusi, Sabrina ^b   Giannelli, Serena G ^a   Venco, Paola ^b   Mazzara, Pietro G ^a   Cozzi, Anna ^a   Ferrari, Maurizio ^a,c   Garavaglia, Barbara ^b   Taverna, Stefano ^a   Tiranti, Valeria ^b   Broccoli, Vania ^a,d   Levi, Sonia ^a,c  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^d CNR   (Italy)

Author keywords

Coenzyme A; hiPSC; iron; neurodegeneration; PKAN

Indexed keywords

COENZYME A; IRON; PANTOTHENATE KINASE 2; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CELL FUNCTION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; ENZYME DEFECT; FEMALE; GENETIC DISORDER; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL LESION; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL NECROSIS; NEURODEGENERATION WITH BRAIN IRON ACCUMULATION; NEWBORN; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

EID: 84989938145     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201606391     Document Type: Article

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