Gene co-expression networks shed light into diseases of brain iron accumulation

Neurobiology of Disease

Volumn 87, Issue , 2016, Pages 59-68

  Bettencourt, Conceição ^a   Forabosco, Paola ^b   Wiethoff, Sarah ^a,g   Heidari, Moones ^c   Johnstone, Daniel M ^d   Botía, Juan A ^e   Collingwood, Joanna F ^f   Hardy, John ^a   Milward, Elizabeth A ^c   Ryten, Mina ^a,e   Houlden, Henry ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UKBEC)   (Italy)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF WARWICK   (United Kingdom)

^g UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Human brain; Iron metabolism; NBIA; WGCNA; Whole transcriptome analysis

Indexed keywords

IRON; TRANSCRIPTOME; HEMOCHROMATOSIS PROTEIN; HFE PROTEIN, MOUSE; HLA ANTIGEN CLASS 1; MEMBRANE PROTEIN; TRANSFERRIN RECEPTOR; TRFR2 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN NERVE CELL; BRAIN REGION; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; IRON OVERLOAD; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; MOUSE; NEURODEGENERATION WITH BRAIN IRON ACCUMULATION; NEUROPATHOLOGY; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPSE; SYSTEMS BIOLOGY; ADOLESCENT; AGED; ANIMAL; CHILD; DISEASE MODEL; GENE EXPRESSION PROFILING; GENETICS; INFANT; IRON METABOLISM DISORDER; METABOLISM; NERVE CELL; NEUROAXONAL DYSTROPHY; PATHOLOGY; PRESCHOOL CHILD; PROCEDURES; TRANSGENIC MOUSE; VALIDATION STUDY; VERY ELDERLY; WHITE MATTER; YOUNG ADULT;

ADOLESCENT; AGED; AGED, 80 AND OVER; ANIMALS; BASAL GANGLIA; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; HEMOCHROMATOSIS PROTEIN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INFANT; IRON; IRON METABOLISM DISORDERS; MALE; MEMBRANE PROTEINS; MICE, TRANSGENIC; NEUROAXONAL DYSTROPHIES; NEURONS; RECEPTORS, TRANSFERRIN; TRANSCRIPTOME; WHITE MATTER; YOUNG ADULT;

EID: 84951860672     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.12.004     Document Type: Article

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