Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 15, 2010, Pages 6988-6993

  Rana, Anil ^a   Seinen, Erwin ^a   Siudeja, Katarzyna ^a   Muntendam, Remco ^b   Srinivasan, Balaji ^a   Van Der Want, Johannes J ^a   Hayflick, Susan ^c   Reijngoud, Dirk Jan ^a   Kayser, Oliver ^b   Sibon, Ody C M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Coenzyme A; Lifespan; Mitochondria; Oxidative stress; PKAN

Indexed keywords

COENZYME A; PANTETHEINE PHOSPHATE; PANTETHINE; PANTOTHENATE KINASE; PANTOTHENIC ACID; VALINOMYCIN;

ARTICLE; BRAIN DEGENERATION; CELL FUNCTION; CONTROLLED STUDY; DROSOPHILA; DRUG MECHANISM; ENZYME SYNTHESIS; FEEDING; HUMAN; HUMAN CELL; INSECT CELL; LIFESPAN; LOCOMOTION; MITOCHONDRION; NERVE DEGENERATION; NONHUMAN; OXIDATION KINETICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; BRAIN; COENZYME A; DROSOPHILA; GENE EXPRESSION REGULATION; HUMANS; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTATION; OXIDATIVE STRESS; OXYGEN; PANTETHEINE; PANTOTHENATE KINASE-ASSOCIATED NEURODEGENERATION; PHENOTYPE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 77951055908     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912105107     Document Type: Article

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