Extracellular 4′-phosphopantetheine is a source for intracellular coenzyme A synthesis

Nature Chemical Biology

Volumn 11, Issue 10, 2015, Pages 784-792

  Srinivasan, Balaji ^a   Baratashvili, Madina ^a   Van Der Zwaag, Marianne ^a   Kanon, Bart ^a   Colombelli, Cristina ^b   Lambrechts, Roald A ^a   Schaap, Onno ^a   Nollen, Ellen A ^c   Podgoršek, Ajda ^d   Kosec, Gregor ^d   Petković, Hrvoje ^d   Hayflick, Susan ^e   Tiranti, Valeria ^b   Reijngoud, Dirk Jan ^a   Grzeschik, Nicola A ^a   Sibon, Ody C M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d ACIES BIO D O O   (Slovenia)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COENZYME A; COENZYME A SYNTHASE; INORGANIC PYROPHOSPHATASE; PANTETHEINE PHOSPHATE; SYNTHETASE; UNCLASSIFIED DRUG; 4'-PHOSPHOPANTETHEINE; COENZYME A LIGASE; PANTETHEINE; PANTOTHENATE KINASE; PHOSPHOTRANSFERASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FUNCTION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOLOGY; DIFFUSION; DROSOPHILA; ENZYME METABOLISM; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; FEMALE; HYDROLYSIS; IN VITRO STUDY; INTRACELLULAR MEMBRANE; MALE; MOLECULE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN STABILITY; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CAENORHABDITIS ELEGANS; CELL LINE; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEK293 CELL LINE; HUMAN; LONGEVITY; METABOLISM; PHYSIOLOGY;

ANIMALS; CAENORHABDITIS ELEGANS; CELL LINE; COENZYME A; COENZYME A LIGASES; DROSOPHILA; FEMALE; HEK293 CELLS; HUMANS; LONGEVITY; MALE; MICE, INBRED C57BL; PANTETHEINE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 84941874187     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1906     Document Type: Article

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