-
1
-
-
84988810120
-
-
D.M.Andersen, G.P.O’Hara, W.R.Brown 1993. RH-3866:dietary oncogenicity study in female mice. final report:Report No. 89R-261. Unpublished study prepared by Rohm and Haas Co. MRID 42809102.
-
(1993)
-
-
Andersen, D.M.1
O’Hara, G.P.2
Brown, W.R.3
-
2
-
-
0026554628
-
UDP-glucuronosyltransferase inducers reduce thyroid hormone levels in rats by an extrathyroidal mechanism
-
R.A.Barter, C.D.Klaassen 1992. UDP-glucuronosyltransferase inducers reduce thyroid hormone levels in rats by an extrathyroidal mechanism. Toxicol Appl Pharmacol. 113:36–42.
-
(1992)
Toxicol Appl Pharmacol
, vol.113
, pp. 36-42
-
-
Barter, R.A.1
Klaassen, C.D.2
-
3
-
-
0036173230
-
Development of an immuno-immobilized androgen receptor assay (IRA) and its application for the characterization of the receptor binding affinity of different pesticides
-
E.R.Bauer, N.Bitsch, H.Brunn, H.Sauerwein, H.H.Meyer 2002. Development of an immuno-immobilized androgen receptor assay (IRA) and its application for the characterization of the receptor binding affinity of different pesticides. Chemosphere. 46:1107–1115.
-
(2002)
Chemosphere
, vol.46
, pp. 1107-1115
-
-
Bauer, E.R.1
Bitsch, N.2
Brunn, H.3
Sauerwein, H.4
Meyer, H.H.5
-
4
-
-
0035721572
-
Dopamine as a prolactin (PRL) inhibitor
-
N.Ben-Jonathan, R.Hnasko 2001. Dopamine as a prolactin (PRL) inhibitor. Endocr Rev. 22:724–763.
-
(2001)
Endocr Rev
, vol.22
, pp. 724-763
-
-
Ben-Jonathan, N.1
Hnasko, R.2
-
5
-
-
84988852204
-
-
E.Bomhard, B.Schilde 1991. MEB 6447:Chronic toxicity and cancerogenicity studies on Wistar rats with administration in diet over a period of 105 weeks:lab project number:20774:101922. Unpublished study prepared by Bayer AG, Dept of Toxicology. MRID 42153901:1029 p.
-
(1991)
-
-
Bomhard, E.1
Schilde, B.2
-
6
-
-
84988852197
-
-
C.Borders, C.Salamon 1985. Two-generation reproduction study in albino rats with CGA-64250 technical. Unpublished study prepared by Toxigenics, Inc. MRID 00151514.
-
(1985)
-
-
Borders, C.1
Salamon, C.2
-
7
-
-
84894286859
-
Relevance weighting of tier 1 endocrine screening endpoints by rank order
-
C.J.Borgert, L.D.Stuchal, E.M.Mihaich, R.A.Becker, K.S.Bentley, J.M.Brausch, K.Coady, D.R.Geter, E.Gordon, P.D.Guiney,. 2014. Relevance weighting of tier 1 endocrine screening endpoints by rank order. Birth Defects Res Part B:Dev Reprod Toxicol. 101:90–113.
-
(2014)
Birth Defects Res Part B: Dev Reprod Toxicol
, vol.101
, pp. 90-113
-
-
Borgert, C.J.1
Stuchal, L.D.2
Mihaich, E.M.3
Becker, R.A.4
Bentley, K.S.5
Brausch, J.M.6
Coady, K.7
Geter, D.R.8
Gordon, E.9
Guiney, P.D.10
-
9
-
-
84888033883
-
Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics
-
C.M.Butt, H.M.Stapleton 2013. Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics. Chem Res Toxicol. 26:1692–1702.
-
(2013)
Chem Res Toxicol
, vol.26
, pp. 1692-1702
-
-
Butt, C.M.1
Stapleton, H.M.2
-
10
-
-
84988845886
-
-
P.Coder 2012. Propiconazole – uterotrophic assay in ovariectomized rats (OECD guideline 440; US EPA OPPTS 890.1600):Unpublished study prepared by WIL Research Laboratories, LLC, Ashland, OH USA. MRID 48619003.
-
(2012)
-
-
Coder, P.1
-
11
-
-
84988845871
-
-
R.Costlow, W.Kane 1984a. Teratology study with RH-53,866 in rats:Final Report:Report No. 83R-024. Unpublished study prepared by Rohm and Haas Co. 123 p. MRID 00141672.
-
(1984)
-
-
Costlow, R.1
Kane, W.2
-
12
-
-
84988843088
-
-
R.Costlow, W.Kane 1984b. Teratology study with RH-53, 866 in rabbits:Report No. 83R-217. Unpublished study prepared by Rohm and Haas Co. 139 p. MRID 00164971.
-
(1984)
-
-
Costlow, R.1
Kane, W.2
-
13
-
-
84988845881
-
-
R.Costlow, J.Harris 1985. RH-53,866:two generation reproduction study in rats:Report No. 84R-117. Unpublished study prepared by Rohm and Haas Co. 225 p. MRID 00149581.
-
(1985)
-
-
Costlow, R.1
Harris, J.2
-
14
-
-
84988843103
-
-
K.K.Coady, L.K.Sosinski 2011. Myclobutanil:evaluation of myclobutanil in the human recombinant aromatase assay. Unpublished study prepared by Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. Laboratory Project Study ID No.:111015, November 28, 2011. MRID 48618103.
-
(2011)
-
-
Coady, K.K.1
Sosinski, L.K.2
-
15
-
-
0029875537
-
A structure–activity relationship for the neurotoxicity of triazole fungicides
-
K.M.Crofton 1996. A structure–activity relationship for the neurotoxicity of triazole fungicides. Toxicol Lett. 84:155–159.
-
(1996)
Toxicol Lett
, vol.84
, pp. 155-159
-
-
Crofton, K.M.1
-
16
-
-
84988843100
-
-
G.Clemens, V.Jasty, C.Troup, R.Hartnagel 1990. A toxicity study in the rabbit with MEB 6447 (Triadimefon):Report No. 100035. Upublished study prepared by Miles Laboratories, Inc. MRID 41616005:179 p.
-
(1990)
-
-
Clemens, G.1
Jasty, V.2
Troup, C.3
Hartnagel, R.4
-
17
-
-
84899822044
-
Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action
-
R.A.Currie, R.C.Peffer, A.K.Goetz, C.J.Omiecinski, J.I.Goodman 2014. Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action. Toxicology 321:80–88.
-
(2014)
Toxicology
, vol.321
, pp. 80-88
-
-
Currie, R.A.1
Peffer, R.C.2
Goetz, A.K.3
Omiecinski, C.J.4
Goodman, J.I.5
-
18
-
-
84988839601
-
-
J.Davis 2011. The Hershberger bioassay (OPPTS 890.1400); triadimefon. Unpublished study prepared by ILS, Integrated Laboratory Systems, Inc. MRID 48619604:107.
-
(2011)
-
-
Davis, J.1
-
19
-
-
33751298289
-
Thiazopyr and thyroid disruption: case study within the context of the 2006 IPCS Human Relevance Framework for analysis of a cancer mode of action
-
V.L.Dellarco, D.McGregor, S.C.Berry, S.M.Cohen, A.R.Boobis 2006. Thiazopyr and thyroid disruption:case study within the context of the 2006 IPCS Human Relevance Framework for analysis of a cancer mode of action. Crit Rev Toxicol. 36:793–801.
-
(2006)
Crit Rev Toxicol
, vol.36
, pp. 793-801
-
-
Dellarco, V.L.1
McGregor, D.2
Berry, S.C.3
Cohen, S.M.4
Boobis, A.R.5
-
20
-
-
84988809150
-
-
R.Eiben 1984. MED 6447 (Triadimefon):Two-Generation Study with Rats:Supplementary Study:Report No. 12712. Unpublished study prepared by Bayer AG, Institute of Toxicology. MRID 155075:168p.
-
(1984)
-
-
Eiben, R.1
-
21
-
-
84988832337
-
-
H.Fritz 1984a. Expanded report on CGA-64250 technical segment II teratology study in rats. Project No. 790011, 21 September 1984. Unpublished study prepared by Ciba-Geigy. Syngenta File No. CGA64250/2150. MRID 00058604.
-
(1984)
-
-
Fritz, H.1
-
22
-
-
84988845257
-
-
H.Fritz 1984b. Expanded report on CGA64250 technical segment II reproductive study in rabbits. Project No. 790009. Unpublished study prepared by Ciba-Geigy. Syngenta File No. CGA64250/2151. MRID 00058605.
-
(1984)
-
-
Fritz, H.1
-
23
-
-
0033771336
-
Prolactin: structure, function, and regulation of secretion
-
M.E.Freeman, B.Kanyicska, A.Lerant, G.Nagy 2000. Prolactin:structure, function, and regulation of secretion. Physiol Rev. 80:1523–1631.
-
(2000)
Physiol Rev
, vol.80
, pp. 1523-1631
-
-
Freeman, M.E.1
Kanyicska, B.2
Lerant, A.3
Nagy, G.4
-
24
-
-
0037006012
-
Reproductive changes in male rats treated perinatally with an aromatase inhibitor
-
D.C.Gerardin, O.C.Pereira 2002. Reproductive changes in male rats treated perinatally with an aromatase inhibitor. Pharmacol Biochem Behav. 71:301–305.
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 301-305
-
-
Gerardin, D.C.1
Pereira, O.C.2
-
25
-
-
84988855379
-
-
M.Giknis 1987. CGA 64250 technical:teratology (segment II) study in rats. Project No.86004. Syngenta File No. CGA64250/1586. Unpublished study prepared by Ciba-Geigy. MRID 40425001.
-
(1987)
-
-
Giknis, M.1
-
26
-
-
33748045120
-
Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides
-
A.K.Goetz, W.Bao, H.Ren, J.E.Schmid, D.B.Tully, C.Wood, J.C.Rockett, M.G.Narotsky, G.Sun, G.R.Lambert,. 2006. Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides. Toxicol Appl Pharmacol. 215:274–284.
-
(2006)
Toxicol Appl Pharmacol
, vol.215
, pp. 274-284
-
-
Goetz, A.K.1
Bao, W.2
Ren, H.3
Schmid, J.E.4
Tully, D.B.5
Wood, C.6
Rockett, J.C.7
Narotsky, M.G.8
Sun, G.9
Lambert, G.R.10
-
27
-
-
67650760524
-
Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals
-
A.K.Goetz, D.J.Dix 2009a. Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals. Toxicol Sci. 110:449–462.
-
(2009)
Toxicol Sci
, vol.110
, pp. 449-462
-
-
Goetz, A.K.1
Dix, D.J.2
-
28
-
-
66049136991
-
Toxicogenomic effects common to triazole antifungals and conserved between rats and humans
-
A.K.Goetz, D.J.Dix 2009b. Toxicogenomic effects common to triazole antifungals and conserved between rats and humans. Toxicol Appl Pharmacol. 238:80–89.
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, pp. 80-89
-
-
Goetz, A.K.1
Dix, D.J.2
-
29
-
-
33845656069
-
Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat
-
A.K.Goetz, H.Ren, J.E.Schmid, C.R.Blystone, I.Thillainadarajah, D.S.Best, H.P.Nichols, L.F.Strader, D.C.Wolf, M.G.Narotsky,. 2007. Disruption of testosterone homeostasis as a mode of action for the reproductive toxicity of triazole fungicides in the male rat. Toxicol Sci. 95:227–239.
-
(2007)
Toxicol Sci
, vol.95
, pp. 227-239
-
-
Goetz, A.K.1
Ren, H.2
Schmid, J.E.3
Blystone, C.R.4
Thillainadarajah, I.5
Best, D.S.6
Nichols, H.P.7
Strader, L.F.8
Wolf, D.C.9
Narotsky, M.G.10
-
30
-
-
72949088372
-
Inhibition of rat and human steroidogenesis by triazole antifungals
-
A.K.Goetz, J.C.Rockett, H.Ren, I.Thillainadarajah, D.J.Dix 2009. Inhibition of rat and human steroidogenesis by triazole antifungals. Syst Biol Reprod Med. 55:214–226.
-
(2009)
Syst Biol Reprod Med
, vol.55
, pp. 214-226
-
-
Goetz, A.K.1
Rockett, J.C.2
Ren, H.3
Thillainadarajah, I.4
Dix, D.J.5
-
31
-
-
84988885272
-
-
P.Goldman, J.Harris 1986. RH-3866:Dietary chronic and oncogenicity study in mice:Final Report:Report Number 84R-023. Unpublished study prepared by Rohm and Haas Co. 3326 p. MRID 00164990.
-
(1986)
-
-
Goldman, P.1
Harris, J.2
-
32
-
-
84988809168
-
-
P.Goldman, J.Harris, K.Lampe 1986a. RH-3866:a three-month dietary toxicity study in mice:Report No. 83R-136. Unpublished study prepared by Rohm & Haas Co. 522 p. MRID 00165245.
-
(1986)
-
-
Goldman, P.1
Harris, J.2
Lampe, K.3
-
33
-
-
84988905511
-
-
P.Goldman, J.Harris, J.Frantz 1986b. RH-3866:one year dietary study in Beagle dogs:Protocol No. 84P-203:Report No. 84R-078. Unpublished study prepared by Rohm & Haas Co. 775 p. MRID 00165248.
-
(1986)
-
-
Goldman, P.1
Harris, J.2
Frantz, J.3
-
34
-
-
33845808673
-
Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides: propiconazole, triadimefon, and myclobutanil
-
S.D.Hester, D.C.Wolf, S.Nesnow, S.F.Thai 2006. Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides:propiconazole, triadimefon, and myclobutanil. Toxicol Pathol. 34:879–894.
-
(2006)
Toxicol Pathol
, vol.34
, pp. 879-894
-
-
Hester, S.D.1
Wolf, D.C.2
Nesnow, S.3
Thai, S.F.4
-
35
-
-
84988805030
-
-
K.Hoffman, P.Groning 1978. Meb 6447 long-term toxicity study on dogs (two-year feeding study):Report No. 7882; Report No. 66656. Unpublished study received Apr 28, 1980 under 3125-318; prepared by Bayer, AG, submitted by Mobay Chemical Corp, Kansas City:Mo; CDL:099413-D. MRID 32539.
-
(1978)
-
-
Hoffman, K.1
Groning, P.2
-
36
-
-
84988885276
-
-
B.Hunter, N.Slater, R.Heywood 1982a. CGA 64 250:potential tumorigenic and toxic effects in prolonged dietary administration to rats:CBG 193/8284 (Test No. 789023). Final rept. Unpublished study prepared by Huntingdon Research Centre, England. MRID 00129918.
-
(1982)
-
-
Hunter, B.1
Slater, N.2
Heywood, R.3
-
37
-
-
84988802625
-
-
B.Hunter, D.Scholey, R.Haywood 1982b. CGA 64 250:long-term feeding study in mice. CBGI195/81827. Final Report. Unpublished study prepared by Huntingdon Research Centre, England. MRID 00129570.
-
(1982)
-
-
Hunter, B.1
Scholey, D.2
Haywood, R.3
-
38
-
-
0032755932
-
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy
-
A.Hood, R.Hashmi, C.D.Klaassen 1999. Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy. Toxicol Appl Pharmacol. 160:163–170.
-
(1999)
Toxicol Appl Pharmacol
, vol.160
, pp. 163-170
-
-
Hood, A.1
Hashmi, R.2
Klaassen, C.D.3
-
39
-
-
0037213832
-
The potential for oestrogenic effects of pesticides in headwater streams in the UK
-
M.R.Hurst, D.A.Sheehan 2003. The potential for oestrogenic effects of pesticides in headwater streams in the UK. Sci Total Environ 301:87–96.
-
(2003)
Sci Total Environ
, vol.301
, pp. 87-96
-
-
Hurst, M.R.1
Sheehan, D.A.2
-
40
-
-
84988855363
-
-
IARC. 1999. Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis, IARC Scientific Publication No. 147. International Agency for Research on Cancer, Lyon, France.
-
(1999)
-
-
-
41
-
-
84988905121
-
-
W.Johnson, S.Thompson 1985. One-year subchronic oral toxicity study in Beagle dogs with CGA-64250 technical (Final Report). FDRL Study No. 7737. Unpublished study prepared by Research Laboratories, Inc. 570 p. Syngenta File No. CGA64250/1544. MRID 00151515.
-
(1985)
-
-
Johnson, W.1
Thompson, S.2
-
42
-
-
27744504199
-
Comparison of regulatory estimates of drinking water concentrations with monitoring data
-
R.L.Jones 2005. Comparison of regulatory estimates of drinking water concentrations with monitoring data. J Agric Food Chem. 53:8835–8839.
-
(2005)
J Agric Food Chem
, vol.53
, pp. 8835-8839
-
-
Jones, R.L.1
-
43
-
-
84947781653
-
Integrated model of chemical perturbations of a biological pathway using 18 in vitro high throughput screening assays for the estrogen receptor
-
R.S.Judson, F.M.Magpantay, V.Chickarmane, C.Haskell, N.Tania, J.Taylor, M.Xia, R.Huang, D.M.Rotroff, D.L.Filer,. 2015. Integrated model of chemical perturbations of a biological pathway using 18 in vitro high throughput screening assays for the estrogen receptor. Toxicol Sci. 148:137–54.
-
(2015)
Toxicol Sci
, vol.148
, pp. 137-154
-
-
Judson, R.S.1
Magpantay, F.M.2
Chickarmane, V.3
Haskell, C.4
Tania, N.5
Taylor, J.6
Xia, M.7
Huang, R.8
Rotroff, D.M.9
Filer, D.L.10
-
44
-
-
84863886918
-
Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management
-
R.Kavlock, K.Chandler, K.Houck, S.Hunter, R.Judson, N.Kleinstreuer, T.Knudsen, M.Martin, S.Padilla, D.Reif,. 2012. Update on EPA's ToxCast program:providing high throughput decision support tools for chemical risk management. Chem Res Toxicol. 25:1287–1302.
-
(2012)
Chem Res Toxicol
, vol.25
, pp. 1287-1302
-
-
Kavlock, R.1
Chandler, K.2
Houck, K.3
Hunter, S.4
Judson, R.5
Kleinstreuer, N.6
Knudsen, T.7
Martin, M.8
Padilla, S.9
Reif, D.10
-
45
-
-
84988905126
-
-
M.B.Kjaerstad, H.R.Andersen, C.Taxvig, U.Hass, M.Axelstad, S.Metzdorff, A.M.Vinggaard 2007. Effects of azole fungicides on the function of sex and thyroid hormones. Pesticides Research No. 111.
-
(2007)
-
-
Kjaerstad, M.B.1
Andersen, H.R.2
Taxvig, C.3
Hass, U.4
Axelstad, M.5
Metzdorff, S.6
Vinggaard, A.M.7
-
46
-
-
10044236969
-
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells
-
H.Kojima, E.Katsura, S.Takeuchi, K.Niiyama, K.Kobayashi 2004. Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect. 112:524–531.
-
(2004)
Environ Health Perspect
, vol.112
, pp. 524-531
-
-
Kojima, H.1
Katsura, E.2
Takeuchi, S.3
Niiyama, K.4
Kobayashi, K.5
-
47
-
-
33750009766
-
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line
-
N.P.Laville, F.Brion, N.Hinfray, C.Casellas, J.-M.Porcher, S.Ait-Aissa 2006. Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology. 228:98–108.
-
(2006)
Toxicology
, vol.228
, pp. 98-108
-
-
Laville, N.P.1
Brion, F.2
Hinfray, N.3
Casellas, C.4
Porcher, J.-M.5
Ait-Aissa, S.6
-
48
-
-
84988809156
-
-
M.J.LeBaron, M.R.Schisler, N.R.Visconti 2011a. Evaluation of myclobutanil in an in vitro estrogen receptor binding assay. Unpublished study prepared by Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. Laboratory Study No.:111118, December 14, 2011. MRID 48618104.
-
(2011)
-
-
LeBaron, M.J.1
Schisler, M.R.2
Visconti, N.R.3
-
49
-
-
84988816020
-
-
M.J.LeBaron, M.R.Schisler, N.R.Visconti 2011b. Evaluation of myclobutanil in an in vitro androgen receptor binding assay. Unpublished study prepared by Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. Laboratory Study No.:111113, December 5, 2011. MRID 48618102.
-
(2011)
-
-
LeBaron, M.J.1
Schisler, M.R.2
Visconti, N.R.3
-
50
-
-
84988873440
-
-
M.J.LeBaron, H.L.Kan 2011c. Evaluation of myclobutanil in an in vitro estrogen receptor transcriptional activation assay in human cell line hERα-HeLa-9903. Unpublished study prepared by Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. Laboratory Report No.:101193, December 12, 2011. MRID 48618105.
-
(2011)
-
-
LeBaron, M.J.1
Kan, H.L.2
-
51
-
-
84988816093
-
-
M.J.LeBaron, H.L.Kan, A.W.Perala 2011d. Evaluation of myclobutanil in the in vitro steroidogenesis assay. Unpublished study prepared by Toxicology & Environmental Research and Consulting, The Dow Chemical Company, Midland, MI. Laboratory Study No.:101192, December 5, 2011. MRID 48618110.
-
(2011)
-
-
LeBaron, M.J.1
Kan, H.L.2
Perala, A.W.3
-
52
-
-
84988901944
-
-
E.Loser, D.Lorke 1979. Meb 6447 Multigeneration Reproduction Study on Rats:Report No. 8297; Report No. 67752. Unpublished study received Apr 28, 1980 under 3125-318; prepared by Bayer, AG, submitted by Mobay Chemical Corp, Kansas City:Mo; CDL:099413-F. MRID 32541.
-
(1979)
-
-
Loser, E.1
Lorke, D.2
-
53
-
-
84988881863
-
-
S.Mallow et al. 1987. CGA 64250:a modified teratology (segment II) study in albino rats. Project No.86189. Syngenta File No. CGA64250/1587. Unpublished study prepared by Ciba-Geigy. MRID 40425002.
-
(1987)
-
-
Mallow, S.1
-
56
-
-
0033377108
-
Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta-estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor
-
M.S.Marty, J.W.Crissman, E.W.Carney 1999. Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta-estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor. Toxicol Sci. 52:269–277.
-
(1999)
Toxicol Sci
, vol.52
, pp. 269-277
-
-
Marty, M.S.1
Crissman, J.W.2
Carney, E.W.3
-
59
-
-
0029563556
-
Mechanistic considerations for the relevance of animal data on thyroid neoplasia to human risk assessment
-
R.M.McClain 1995. Mechanistic considerations for the relevance of animal data on thyroid neoplasia to human risk assessment. Mutat Res. 333:131–142.
-
(1995)
Mutat Res
, vol.333
, pp. 131-142
-
-
McClain, R.M.1
-
61
-
-
84988832416
-
-
J.E.McLaughlin, L.J.DiDonato 1984. RH-3866:a three month dietary study in dogs. Unpublished study report prepared by Rohm and Hass Company, a wholly-owned subsidiary of The Dow Chemical Company, Midland, Michigan.
-
(1984)
-
-
McLaughlin, J.E.1
DiDonato, L.J.2
-
62
-
-
84988855426
-
-
U.Mohr 1976. Meb 6447:Subchronic Toxicity Study on Rats (Twelve-week Feeding Experiment):Report No. R 840a; Report No. 44300. Unpublished study received Aug 15, 1977 under 3125-318; prepared by Medizinische Hochschule Hannover, Abteilung fur Experimentalle Pathologie, West Germany, submitted by Mobay Chemical Corp, Kansas City, Mo; CDL:2311312-C.
-
(1976)
-
-
Mohr, U.1
-
63
-
-
0030346704
-
Use of a specific aromatase inhibitor for determining whether there is a role for oestrogen in follicle/oocyte maturation, ovulation and preimplantation embryo development
-
N.R.Moudgal, G.Shetty, N.Selvaraj, A.S.Bhatnagar 1996. Use of a specific aromatase inhibitor for determining whether there is a role for oestrogen in follicle/oocyte maturation, ovulation and preimplantation embryo development. J Reprod Fertil Suppl. 50:69–81.
-
(1996)
J Reprod Fertil Suppl
, vol.50
, pp. 69-81
-
-
Moudgal, N.R.1
Shetty, G.2
Selvaraj, N.3
Bhatnagar, A.S.4
-
64
-
-
84876733947
-
Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals
-
A.J.Murk, E.Rijntjes, B.J.Blaauboer, R.Clewell, K.M.Crofton, M.M.Dingemans, J.D.Furlow, R.Kavlock, J.Kohrle, R.Opitz,. 2013. Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals. Toxicol In Vitro:Int J Published Assoc BIBRA. 27:1320–1346.
-
(2013)
Toxicol In Vitro: Int J Published Assoc BIBRA
, vol.27
, pp. 1320-1346
-
-
Murk, A.J.1
Rijntjes, E.2
Blaauboer, B.J.3
Clewell, R.4
Crofton, K.M.5
Dingemans, M.M.6
Furlow, J.D.7
Kavlock, R.8
Kohrle, J.9
Opitz, R.10
-
65
-
-
84988827761
-
-
K.Nagumo, Y.Teraki, T.Chiba 1981. Teratogenicity test of MEB 6447 in pregnant rats:submitter 80257. Unpublished study received Jan 5, 1982 under 1F2474; prepared by St Marianna Univ, First Dept of Anatomy, Laboratory of Embryology, submitted by Mobay Chemical Corp, Kansas City, Mo; CDL:070570-A. MRID 89023.
-
(1981)
-
-
Nagumo, K.1
Teraki, Y.2
Chiba, T.3
-
66
-
-
0030250888
-
Recovery of reproductive function in rats treated with the aromatase inhibitor fadrozole
-
S.B.Nunez, R.P.Blye, P.M.Thomas, J.R.Reel, K.M.Barnes, J.D.Malley, G.B.CutlerJr.1996. Recovery of reproductive function in rats treated with the aromatase inhibitor fadrozole. Reprod Toxicol. 10:373–377.
-
(1996)
Reprod Toxicol
, vol.10
, pp. 373-377
-
-
Nunez, S.B.1
Blye, R.P.2
Thomas, P.M.3
Reel, J.R.4
Barnes, K.M.5
Malley, J.D.6
Cutler, G.B.7
-
67
-
-
84988816092
-
-
OECD. 2012. Guidance Document on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption, Environment Directorate, Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology, 524.
-
(2012)
-
-
-
68
-
-
84988861195
-
-
G.O’Hara, L.DiDonato 1984. RH-3866:three month dietary toxicity study in rats:Final Report:Report No. 83R-068. Unpublished study prepared by Rohm and Haas Co. 702 p. MRID 00145048.
-
(1984)
-
-
O’Hara, G.1
DiDonato, L.2
-
69
-
-
80053440198
-
Multi-species analyses of direct activators of the constitutive androstane receptor
-
C.J.Omiecinski, D.M.Coslo, T.Chen, E.M.Laurenzana, R.C.Peffer 2011. Multi-species analyses of direct activators of the constitutive androstane receptor. Toxicol Sci. 123:550–562.
-
(2011)
Toxicol Sci
, vol.123
, pp. 550-562
-
-
Omiecinski, C.J.1
Coslo, D.M.2
Chen, T.3
Laurenzana, E.M.4
Peffer, R.C.5
-
70
-
-
9944266190
-
A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA
-
K.Ohno, N.Araki, T.Yanase, H.Nawata, M.Iida 2004. A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA. Toxicological Sci. 82:443–450.
-
(2004)
Toxicological Sci
, vol.82
, pp. 443-450
-
-
Ohno, K.1
Araki, N.2
Yanase, T.3
Nawata, H.4
Iida, M.5
-
71
-
-
84978901238
-
Tiered high-throughput screening approach to identify thyroperoxidase inhibitors within the ToxCast Phase I and II chemical libraries
-
K.Paul Friedman, E.D.Watt, M.W.Hornung, J.M.Hedge, R.S.Judson, K.M.Crofton, K.A.Houck, S.O.Simmons 2016. Tiered high-throughput screening approach to identify thyroperoxidase inhibitors within the ToxCast Phase I and II chemical libraries. Toxicol Sci. 151:160–80.
-
(2016)
Toxicol Sci
, vol.151
, pp. 160-180
-
-
Paul Friedman, K.1
Watt, E.D.2
Hornung, M.W.3
Hedge, J.M.4
Judson, R.S.5
Crofton, K.M.6
Houck, K.A.7
Simmons, S.O.8
-
72
-
-
84896353700
-
Development of a thyroperoxidase inhibition assay for high-throughput screening
-
K.B.Paul, J.M.Hedge, D.M.Rotroff, M.W.Hornung, K.M.Crofton, S.O.Simmons 2014. Development of a thyroperoxidase inhibition assay for high-throughput screening. Chem Res Toxicol. 27:387–399.
-
(2014)
Chem Res Toxicol
, vol.27
, pp. 387-399
-
-
Paul, K.B.1
Hedge, J.M.2
Rotroff, D.M.3
Hornung, M.W.4
Crofton, K.M.5
Simmons, S.O.6
-
73
-
-
84883337504
-
Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors
-
K.B.Paul, J.T.Thompson, S.O.Simmons, J.P.Vanden Heuvel, K.M.Crofton 2013. Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors. Toxicol In Vitro:Int J Publ Assoc BIBRA. 27:2049–2060.
-
(2013)
Toxicol In Vitro: Int J Publ Assoc BIBRA
, vol.27
, pp. 2049-2060
-
-
Paul, K.B.1
Thompson, J.T.2
Simmons, S.O.3
Vanden Heuvel, J.P.4
Crofton, K.M.5
-
74
-
-
84890314265
-
Assessment of a nonsteroidal aromatase inhibitor, letrozole, in juvenile rats
-
L.Pouliot, M.Schneider, M.De Cristofaro, R.Samadfam, S.Y.Smith, D.A.Beckman 2013. Assessment of a nonsteroidal aromatase inhibitor, letrozole, in juvenile rats. Birth Defects Res Part B:Dev Reprod Toxicol. 98:374–390.
-
(2013)
Birth Defects Res Part B: Dev Reprod Toxicol
, vol.98
, pp. 374-390
-
-
Pouliot, L.1
Schneider, M.2
De Cristofaro, M.3
Samadfam, R.4
Smith, S.Y.5
Beckman, D.A.6
-
75
-
-
84905224441
-
The effects of bromocriptine treatment during early pregnancy on postpartum maternal behaviors in rats
-
A.K.Price, R.S.Bridges 2014. The effects of bromocriptine treatment during early pregnancy on postpartum maternal behaviors in rats. Dev Psychobiol. 56:1431–1437.
-
(2014)
Dev Psychobiol
, vol.56
, pp. 1431-1437
-
-
Price, A.K.1
Bridges, R.S.2
-
76
-
-
84988816113
-
-
D.Raab, M.Youreneff, M.Giknis,. 1987. Propiconazole:a teratology study in New Zealand rabbits:final report amendment No. 1:Laboratory Project ID 86043. Unpublished study prepared by Ciba-Geigy. Syngenta File No. CGA64250/1589. MRID 40425004.
-
(1987)
-
-
Raab, D.1
Youreneff, M.2
Giknis, M.3
-
77
-
-
0002174470
-
Bromocriptine
-
Laurence D.R., McLean A.E.M., Weatherall M., (eds), London, UK: Academic Press
-
B.P.Richardson, I.Turkalji, E.Fluckiger 1984. Bromocriptine. In:D.R.Laurence, A.E.M.McLean, M.Weatherall, editors. Safety testing of new drugs. London, UK:Academic Press. p. 19–63.
-
(1984)
Safety testing of new drugs
, pp. 19-63
-
-
Richardson, B.P.1
Turkalji, I.2
Fluckiger, E.3
-
79
-
-
33749595073
-
Effect of conazole fungicides on reproductive development in the female rat
-
J.C.Rockett, M.G.Narotsky, K.E.Thompson, I.Thillainadarajah, C.R.Blystone, A.K.Goetz, H.Ren, D.S.Best, R.N.Murrell, H.P.Nichols,. 2006. Effect of conazole fungicides on reproductive development in the female rat. Reprod Toxicol. 22:647–658.
-
(2006)
. Reprod Toxicol
, vol.22
, pp. 647-658
-
-
Rockett, J.C.1
Narotsky, M.G.2
Thompson, K.E.3
Thillainadarajah, I.4
Blystone, C.R.5
Goetz, A.K.6
Ren, H.7
Best, D.S.8
Murrell, R.N.9
Nichols, H.P.10
-
80
-
-
77953983411
-
Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals
-
D.M.Rotroff, A.L.Beam, D.J.Dix, A.Farmer, K.M.Freeman, K.A.Houck, R.S.Judson, E.L.Le Cluyse, M.T.Martin, D.M.Reif, S.S.Ferguson 2010. Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals. J Toxicol Environ Health Part B:Crit Rev. 13:329–346.
-
(2010)
J Toxicol Environ Health Part B: Crit Rev
, vol.13
, pp. 329-346
-
-
Rotroff, D.M.1
Beam, A.L.2
Dix, D.J.3
Farmer, A.4
Freeman, K.M.5
Houck, K.A.6
Judson, R.S.7
Le Cluyse, E.L.8
Martin, M.T.9
Reif, D.M.10
Ferguson, S.S.11
-
81
-
-
84871008938
-
Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals
-
D.M.Rotroff, D.J.Dix, K.A.Houck, T.B.Knudsen, M.T.Martin, K.W.McLaurin, D.M.Reif, K.M.Crofton, A.V.Singh, M.Xia,. 2013. Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals. Environ Health Perspect. 121:7–14.
-
(2013)
Environ Health Perspect
, vol.121
, pp. 7-14
-
-
Rotroff, D.M.1
Dix, D.J.2
Houck, K.A.3
Knudsen, T.B.4
Martin, M.T.5
McLaurin, K.W.6
Reif, D.M.7
Crofton, K.M.8
Singh, A.V.9
Xia, M.10
-
82
-
-
84905638971
-
Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses
-
D.M.Rotroff, M.T.Martin, D.J.Dix, D.L.Filer, K.A.Houck, T.B.Knudsen, N.S.Sipes, D.M.Reif, M.Xia, R.Huang, R.S.Judson 2014. Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses. Environ Sci Technol. 48:8706–8716.
-
(2014)
. Environ Sci Technol
, vol.48
, pp. 8706-8716
-
-
Rotroff, D.M.1
Martin, M.T.2
Dix, D.J.3
Filer, D.L.4
Houck, K.A.5
Knudsen, T.B.6
Sipes, N.S.7
Reif, D.M.8
Xia, M.9
Huang, R.10
Judson, R.S.11
-
83
-
-
84922476606
-
Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors
-
D.Rouquie, H.Tinwell, O.Blanck, F.Schorsch, D.Geter, S.Wason, R.Bars 2014. Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors. Regul Toxicol Pharmacol. 70:673–680.
-
(2014)
. Regul Toxicol Pharmacol
, vol.70
, pp. 673-680
-
-
Rouquie, D.1
Tinwell, H.2
Blanck, O.3
Schorsch, F.4
Geter, D.5
Wason, S.6
Bars, R.7
-
84
-
-
0036070511
-
Induction and Inhibition of aromatase (CYP 19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells
-
I.T.Sanderson, J.Boerma, G.W.A.Lansbergen, M.van den Berg 2002. Induction and Inhibition of aromatase (CYP 19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells. Toxicol Appl Pharmacol. 182, 44–54.
-
(2002)
Toxicol Appl Pharmacol
, vol.182
, pp. 44-54
-
-
Sanderson, I.T.1
Boerma, J.2
Lansbergen, G.W.A.3
van den Berg, M.4
-
85
-
-
84988906191
-
-
K.Sachsse, P.Suter, H.Luetkemeier 1979a. CGA-64250 Techn. Three months toxicity study on rats:Project No. 790014. Final rept. Unpublished study prepared by Ciba Geigy Ltd., Switzerland, Syngenta File No. 64250/1538. MRID 00058606.
-
(1979)
-
-
Sachsse, K.1
Suter, P.2
Luetkemeier, H.3
-
86
-
-
84988885315
-
-
K.Sachsse, R.Bathe, H.Luetkemeier 1979b. CGA-64250 3-month toxicity study on dogs:Report No. 78/5751. CDL:244271-R. Final rept. Unpublished study prepared by Ciba Geigy Ltd., Switzerland. Syngenta File No. CGA64250/1539. MRID 00058607.
-
(1979)
-
-
Sachsse, K.1
Bathe, R.2
Luetkemeier, H.3
-
87
-
-
84920267321
-
Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital
-
A.Schraplau, B.Schewe, F.Neuschafer-Rube, S.Ringel, C.Neuber, B.Kleuser, G.P.Puschel 2015. Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital. Toxicology 328:21–28.
-
(2015)
Toxicology
, vol.328
, pp. 21-28
-
-
Schraplau, A.1
Schewe, B.2
Neuschafer-Rube, F.3
Ringel, S.4
Neuber, C.5
Kleuser, B.6
Puschel, G.P.7
-
88
-
-
84988873422
-
-
L.P.Sheets, R.Gilmore, H.Hoss 2008. A developmental neurotoxicity study with technical grade triadimefon in wistar rats. Project Number 07/D72/IL, 201766. Unpublished study prepared by Bayer CropScience. p. 1179.
-
(2008)
-
-
Sheets, L.P.1
Gilmore, R.2
Hoss, H.3
-
89
-
-
84988827734
-
-
T.Shellenberger, L.Billups 1986. Chronic toxicity and oncogenicity study with RH 3866 in rats:final report:Project No. 8342. Unpublished study prepared by Rohm & Haas Co. Project No. 85RC-61 prepared by Tegeris Laboratories, Inc. 3536 p. MRID 00165247.
-
(1986)
-
-
Shellenberger, T.1
Billups, L.2
-
90
-
-
84988827733
-
-
Y.Shimizu 1987. A thirteen week feeding subchronic study of RH-3866 in rats. Report No. NRILS 86-2024;R & H Report No 87RC-038. Unpublished study from NRI Life Science, Kanagawa, Japan and prepared by Rohm & Haas Co. 09 July 1987.
-
(1987)
-
-
Shimizu, Y.1
-
91
-
-
0034029020
-
Endocrine-disrupting chemicals: prepubertal exposures and effects on sexual maturation and thyroid function in the male rat. A focus on the EDSTAC recommendations. Endocrine Disrupter Screening and Testing Advisory Committee
-
T.E.Stoker, L.G.Parks, L.E.Gray, R.L.Cooper 2000. Endocrine-disrupting chemicals:prepubertal exposures and effects on sexual maturation and thyroid function in the male rat. A focus on the EDSTAC recommendations. Endocrine Disrupter Screening and Testing Advisory Committee. Crit Rev Toxicol. 30:197–252.
-
(2000)
Crit Rev Toxicol
, vol.30
, pp. 197-252
-
-
Stoker, T.E.1
Parks, L.G.2
Gray, L.E.3
Cooper, R.L.4
-
92
-
-
84893364226
-
Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes
-
T.Sueyoshi, L.Li, H.Wang, R.Moore, P.R.Kodavanti, H.J.Lehmler, M.Negishi, L.S.Birnbaum 2014. Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes. Toxicol Sci. 137:292–302.
-
(2014)
Toxicol Sci
, vol.137
, pp. 292-302
-
-
Sueyoshi, T.1
Li, L.2
Wang, H.3
Moore, R.4
Kodavanti, P.R.5
Lehmler, H.J.6
Negishi, M.7
Birnbaum, L.S.8
-
93
-
-
1542271014
-
The effects of the aromatase inhibitor fadrozole hydrochloride on fetuses and uteri in late pregnant rats
-
H.Tamada, Y.Shimizu, T.Inaba, N.Kawate, T.Sawada 2004. The effects of the aromatase inhibitor fadrozole hydrochloride on fetuses and uteri in late pregnant rats. J Endocrinol. 180:337–345.
-
(2004)
J Endocrinol
, vol.180
, pp. 337-345
-
-
Tamada, H.1
Shimizu, Y.2
Inaba, T.3
Kawate, N.4
Sawada, T.5
-
94
-
-
40349100229
-
Endocrine-disrupting properties in vivo of widely used azole fungicides
-
C.Taxvig, A.M.Vinggaard, U.Hass, M.Axelstad, S.Metzdorff, C.Nellemann 2008. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl. 31:170–177.
-
(2008)
Int J Androl
, vol.31
, pp. 170-177
-
-
Taxvig, C.1
Vinggaard, A.M.2
Hass, U.3
Axelstad, M.4
Metzdorff, S.5
Nellemann, C.6
-
95
-
-
70350499883
-
Impact of estrogen replacement on letrozole-induced embryopathic effects
-
G.M.Tiboni, F.Marotta, A.P.Castigliego, C.Rossi 2009. Impact of estrogen replacement on letrozole-induced embryopathic effects. Hum Reprod. 24:2688–2692.
-
(2009)
. Hum Reprod
, vol.24
, pp. 2688-2692
-
-
Tiboni, G.M.1
Marotta, F.2
Castigliego, A.P.3
Rossi, C.4
-
96
-
-
47649116188
-
Effects of the aromatase inhibitor letrozole on in utero development in rats
-
G.M.Tiboni, F.Marotta, C.Rossi, F.Giampietro 2008. Effects of the aromatase inhibitor letrozole on in utero development in rats. Hum Reprod. 23:1719–1723.
-
(2008)
. Hum Reprod
, vol.23
, pp. 1719-1723
-
-
Tiboni, G.M.1
Marotta, F.2
Rossi, C.3
Giampietro, F.4
-
98
-
-
36349019788
-
In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases
-
Z.Tong, H.Li, I.Goljer, O.McConnell, A.Chandrasekaran 2007. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos:Biol Fate Chem. 35:2203–2210.
-
(2007)
Drug Metab Dispos: Biol Fate Chem
, vol.35
, pp. 2203-2210
-
-
Tong, Z.1
Li, H.2
Goljer, I.3
McConnell, O.4
Chandrasekaran, A.5
-
99
-
-
7544250772
-
Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans
-
E.R.Trosken, K.Scholz, R.W.Lutz, W.Volkel, J.A.Zarn, W.K.Lutz 2004. Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res. 30:387–394.
-
(2004)
Endocr Res
, vol.30
, pp. 387-394
-
-
Trosken, E.R.1
Scholz, K.2
Lutz, R.W.3
Volkel, W.4
Zarn, J.A.5
Lutz, W.K.6
-
100
-
-
33749667750
-
Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles
-
E.R.Trosken, M.Adamska, M.Arand, J.A.Zarn, C.Patten, W.Volkel, W.K.Lutz 2006a. Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology 228:24–32.
-
(2006)
Toxicology
, vol.228
, pp. 24-32
-
-
Trosken, E.R.1
Adamska, M.2
Arand, M.3
Zarn, J.A.4
Patten, C.5
Volkel, W.6
Lutz, W.K.7
-
101
-
-
31044449968
-
Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation
-
E.R.Trosken, K.Fischer, W.Volkel, W.K.Lutz 2006b. Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation. Toxicology 219:33–40.
-
(2006)
Toxicology
, vol.219
, pp. 33-40
-
-
Trosken, E.R.1
Fischer, K.2
Volkel, W.3
Lutz, W.K.4
-
102
-
-
33746914451
-
Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides
-
D.B.Tully, W.Bao, A.K.Goetz, C.R.Blystone, H.Ren, J.E.Schmid, L.F.Strader, C.R.Wood, D.S.Best, M.G.Narotsky,. 2006. Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides. Toxicol Appl Pharmacol. 215:260–273.
-
(2006)
. Toxicol Appl Pharmacol
, vol.215
, pp. 260-273
-
-
Tully, D.B.1
Bao, W.2
Goetz, A.K.3
Blystone, C.R.4
Ren, H.5
Schmid, J.E.6
Strader, L.F.7
Wood, C.R.8
Best, D.S.9
Narotsky, M.G.10
-
103
-
-
84988823823
-
-
T.Unger, D.Van Goethem, T.Shellenberger 1982. A teratological evaluation of bayleton in mated female rats:MRI Project No. 7272-B. Unpublished study prepared by Midwest Research Institute.MRID 149336:52 p.
-
(1982)
-
-
Unger, T.1
Van Goethem, D.2
Shellenberger, T.3
-
104
-
-
84988823824
-
-
USEPA. 2007a. Integrated Summary Report on Aromatase.
-
(2007)
-
-
-
105
-
-
84988833215
-
-
USEPA. 2007b. Myclobutanil:Acute and Chronic Food and Drinking Water Dietary Exposure and Risk Assessments for Section 3 Use on Snap Bean, Mint, Papaya, Gooseberry, Currant, Caneberry, Bell and Non-Bell Pepper, Head and Leaf Lettuce, and Artichoke PC Code 128857 DP 341690.
-
(2007)
-
-
-
106
-
-
84988799633
-
-
USEPA. 2008. Mycobutanil:Amended Human Health Risk Assessment for Proposed Use on Section 3 Requests for Use on Snap Bean, Mint, Papaya, Gooseberry, Currant, Caneberry, Bell and Non-Bell Pepper, Head and Leaf Lettuce, and Artichoke PC Code 128857 DP Barcode:341689.
-
(2008)
-
-
-
107
-
-
84988823386
-
-
USEPA. 2009. Triadimefon:Human Health Risk Assessment to Support Reinstatement of Use on Residential Turf Decision No. 391164.38.
-
(2009)
-
-
-
108
-
-
84988828442
-
-
USEPA. 2011. US EPA EDSP21 Work Plan. Available from:https://wwwepagov/endocrine-disruption/endocrine-disruptor-screening-program-21st-century-edsp21-workplan-summary.
-
(2011)
-
-
-
109
-
-
84988828441
-
-
USEPA. 2012. Prioritization of the Endocrine Disruptor Screening Program Universe of Chemicals for an Estrogen Receptor Adverse Outcome Pathway Using Computational Toxicology Tools. Available from:https://wwwregulationsgov/#!documentDetail;D=EPA-HQ-OPP-2012-0818-0017.
-
(2012)
-
-
-
110
-
-
84988833216
-
-
USEPA. 2013. Information Collection Request for the Endocrine Disruptor Screening Program, EPA ICR #2488.01, Attachment F:Calculations for Paperwork Burden and Costs for Data Generation Activities.
-
(2013)
-
-
-
111
-
-
84988833233
-
-
USEPA. 2014a. Endocrine Disruptor Screening Program Comprehensive Management Plan.
-
(2014)
-
-
-
112
-
-
84988842964
-
-
USEPA. 2014b. Integrated Bioactivity and Exposure Ranking:A Computational Approach for the Prioritization and Screening of Chemicals in the Endocrine Disruptor Screening Program. Available from:http://www.regulations.gov/#!documentDetail;D = EPA-HQ-OPP-2014-0614-0003.
-
(2014)
-
-
-
113
-
-
84988833244
-
-
USEPA. 2014c. New High-throughput Methods to Estimate Chemical Exposure.
-
(2014)
-
-
-
114
-
-
84988828459
-
-
USEPA. 2014d. Propiconazole Human Health Risk Assessment for the Section 3 Registration on Rapeseed Crop Subgroup 20A.
-
(2014)
-
-
-
115
-
-
84988828454
-
-
USEPA. 2014e. ToxCast Data Invitrodb_v1.
-
(2014)
-
-
-
116
-
-
84988828469
-
-
USEPA. 2015a. Endocrine Disruptor Screening Program Tier 1 Assessments. Available from:http://www2epagov/ingredients-used-pesticide-products/endocrine-disruptor-screening-program-tier-1-assessments.
-
(2015)
-
-
-
117
-
-
84988842968
-
-
USEPA. 2015b. Use of High-Throughput Assays and Computational Tools; Endocrine Disruptor Screening Program; Notice of Availability and Opportunity for Comment. Available from:http://federalregister.gov/a/2015-15182, Federal Register.
-
(2015)
-
-
-
118
-
-
0036176692
-
Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation
-
N.R.Vansell, C.D.Klaassen 2002. Increase in rat liver UDP-glucuronosyltransferase mRNA by microsomal enzyme inducers that enhance thyroid hormone glucuronidation. Drug Metab Dispos:Biol Fate Chem. 30:240–246.
-
(2002)
Drug Metab Dispos: Biol Fate Chem
, vol.30
, pp. 240-246
-
-
Vansell, N.R.1
Klaassen, C.D.2
-
119
-
-
0034106868
-
Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro
-
A.M.Vinggaard, C.Hnida, V.Breinholt, J.C.Larsen 2000. Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro. Toxicol in vitro. 14:227–234.
-
(2000)
Toxicol in vitro
, vol.14
, pp. 227-234
-
-
Vinggaard, A.M.1
Hnida, C.2
Breinholt, V.3
Larsen, J.C.4
-
120
-
-
0030220632
-
Triadimefon and triadimenol: effects on monoamine uptake and release
-
Q.D.Walker, R.B.Mailman 1996. Triadimefon and triadimenol:effects on monoamine uptake and release. Toxicol Appl Pharmacol. 139:227–233.
-
(1996)
. Toxicol Appl Pharmacol
, vol.139
, pp. 227-233
-
-
Walker, Q.D.1
Mailman, R.B.2
-
121
-
-
84881403843
-
High-throughput models for exposure-based chemical prioritization in the ExpoCast project
-
J.F.Wambaugh, R.W.Setzer, D.M.Reif, S.Gangwal, J.Mitchell-Blackwood, J.A.Arnot, O.Joliet, A.Frame, J.Rabinowitz, T.B.Knudsen,. 2013. High-throughput models for exposure-based chemical prioritization in the ExpoCast project. Environ Sci Technol. 47:8479–8488.
-
(2013)
. Environ Sci Technol
, vol.47
, pp. 8479-8488
-
-
Wambaugh, J.F.1
Setzer, R.W.2
Reif, D.M.3
Gangwal, S.4
Mitchell-Blackwood, J.5
Arnot, J.A.6
Joliet, O.7
Frame, A.8
Rabinowitz, J.9
Knudsen, T.B.10
-
122
-
-
84908577609
-
High throughput heuristics for prioritizing human exposure to environmental chemicals
-
J.F.Wambaugh, A.Wang, K.L.Dionisio, A.Frame, P.Egeghy, R.Judson, R.W.Setzer 2014. High throughput heuristics for prioritizing human exposure to environmental chemicals. Environ Sci Technol. 48:12760–12767.
-
(2014)
. Environ Sci Technol
, vol.48
, pp. 12760-12767
-
-
Wambaugh, J.F.1
Wang, A.2
Dionisio, K.L.3
Frame, A.4
Egeghy, P.5
Judson, R.6
Setzer, R.W.7
-
123
-
-
84930085761
-
Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment
-
B.A.Wetmore 2014. Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment. Toxicology. 332:94–101.
-
(2014)
Toxicology
, vol.332
, pp. 94-101
-
-
Wetmore, B.A.1
-
124
-
-
84555187264
-
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment
-
B.A.Wetmore, J.F.Wambaugh, S.S.Ferguson, M.A.Sochaski, D.M.Rotroff, K.Freeman, H.J.ClewellIII, D.J.Dix, M.E.Andersen, K.A.Houck,. 2012. Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicol Sci. 125:157–174.
-
(2012)
Toxicol Sci
, vol.125
, pp. 157-174
-
-
Wetmore, B.A.1
Wambaugh, J.F.2
Ferguson, S.S.3
Sochaski, M.A.4
Rotroff, D.M.5
Freeman, K.6
Clewell, H.J.7
Dix, D.J.8
Andersen, M.E.9
Houck, K.A.10
-
125
-
-
84988842897
-
-
G.W.Wolfe 1993. RH-3866 technical:104-week dietary oncogenicity toxicity study in rats. Report No. 89RC-260Unpublished study prepared by Rohm & Haas Co. 522 p. MRID 42809101.
-
(1993)
-
-
Wolfe, G.W.1
-
126
-
-
80052429397
-
Application of an integrated testing strategy to the U.S. EPA endocrine disruptor screening program
-
C.E.Willett, P.L.Bishop, K.M.Sullivan 2011. Application of an integrated testing strategy to the U.S. EPA endocrine disruptor screening program. Toxicol Sci. 123:15–25.
-
(2011)
Toxicol Sci
, vol.123
, pp. 15-25
-
-
Willett, C.E.1
Bishop, P.L.2
Sullivan, K.M.3
-
130
-
-
84892712724
-
Comparison of simulated pesticide concentrations in surface drinking water with monitoring data: explanations for observed differences and proposals for a new regulatory modeling approach
-
M.F.Winchell, N.J.Snyder 2014. Comparison of simulated pesticide concentrations in surface drinking water with monitoring data:explanations for observed differences and proposals for a new regulatory modeling approach. J Agric Food Chem. 62:348–359.
-
(2014)
. J Agric Food Chem
, vol.62
, pp. 348-359
-
-
Winchell, M.F.1
Snyder, N.J.2
-
131
-
-
33845793865
-
Toxicity profiles in rats treated with tumorigenic and nontumorigenic triazole conazole fungicides: propiconazole, triadimefon, and myclobutanil
-
D.C.Wolf, J.W.Allen, M.H.George, S.D.Hester, G.Sun, T.Moore, S.F.Thai, D.Delker, E.Winkfield, S.Leavitt,. 2006. Toxicity profiles in rats treated with tumorigenic and nontumorigenic triazole conazole fungicides:propiconazole, triadimefon, and myclobutanil. Toxicol Pathol. 34:895–902.
-
(2006)
Toxicol Pathol
, vol.34
, pp. 895-902
-
-
Wolf, D.C.1
Allen, J.W.2
George, M.H.3
Hester, S.D.4
Sun, G.5
Moore, T.6
Thai, S.F.7
Delker, D.8
Winkfield, E.9
Leavitt, S.10
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