Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells

Toxicology and Applied Pharmacology

Volumn 182, Issue 1, 2002, Pages 44-54

  Sanderson, J Thomas ^a   Boerma, Joke ^a   Lansbergen, Gideon W A ^a   Van Den Berg, Martin ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Aromatase; Atrazine; cAMP; Endocrine disruption; Fungicides; H295R; Herbicides; Imidazole; Induction; Inhibition; Organotin; Pesticides; Triazine; Triazole

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 1,1,1 TRICHLORO 2 (2 CHLOROPHENYL) 2 (4 CHLOROPHENYL)ETHANE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AROMATASE; AROMATASE INHIBITOR; ATRAZINE; CHLORPHENOTANE; DIBUTYLTIN CHLORIDE; DIFENOCONAZOLE; ENILCONAZOLE; ETHOXYRESORUFIN DEETHYLASE; FENARIMOL; FUNGICIDE; HEXACONAZOLE; IMIDAZOLE; MESSENGER RNA; NEUTRAL RED; PENCONAZOLE; PESTICIDE; PROCHLORAZ; PROPICONAZOLE; STEROID HORMONE; TEBUCONAZOLE; TRIBUTYLTIN CHLORIDE; TRIPHENYLTIN CHLORIDE; UNCLASSIFIED DRUG; VINCLOZOLIN;

ADRENAL CORTEX CARCINOMA; ARTICLE; CANCER CELL; CATALYSIS; CELL STRAIN; CELL VIABILITY; COMPETITIVE INHIBITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; EXPOSURE; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MITOCHONDRION; TIME;

EID: 0036070511     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2002.9420     Document Type: Article

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