A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA

Toxicological Sciences

Volumn 82, Issue 2, 2004, Pages 443-450

  Ohno, Ken ^a   Araki, Naohiro ^a   Yanase, Toshihiko ^c   Nawata, Hajime ^b   Iida, Mitsuru ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NONE

Author keywords

Aromatase; Benomyl; Endocrine disrupter; KGN cell line; Screening assay

Indexed keywords

1,1,1 TRICHLORO 2 (2 CHLOROPHENYL) 2 (4 CHLOROPHENYL)ETHANE; 7 HYDROXYFLAVONE; ALPHA NAPHTHOFLAVONE; AMINOGLUTETHIMIDE; ANDROGEN; ANDROSTENEDIONE; APIGENIN; AROMATASE; ATRAZINE; BENOMYL; CHLORPHENOTANE; CHRYSIN; ENILCONAZOLE; ESTRADIOL; ESTRIOL; ESTRONE; FENARIMOL; FLAVANONE; FLAVONE; FORMESTANE; FORSKOLIN; NARINGENIN; PROGESTERONE; PROPICONAZOLE; TESTOSTERONE; TRIADIMEFON; TRIBUTYLTIN CHLORIDE; TRIPHENYLTIN CHLORIDE; VINCLOZOLIN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DIAGNOSTIC KIT; ENDOCRINE FUNCTION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GRANULOSA CELL TUMOR; HUMAN; HUMAN CELL; IN VITRO STUDY; PROCESS OPTIMIZATION; SAMPLE SIZE; SCREENING TEST; TOXICITY TESTING; TUMOR CELL LINE;

AROMATASE; BENOMYL; CELL LINE, TUMOR; CELL SURVIVAL; CROSS REACTIONS; ENZYME INDUCTION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRONE; FEMALE; FUNGICIDES, INDUSTRIAL; GRANULOSA CELL TUMOR; HUMANS; OVARIAN NEOPLASMS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; XENOBIOTICS;

EID: 9944266190     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh292     Document Type: Article

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