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Volumn 35, Issue 21, 2016, Pages 2332-2349

A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP

Author keywords

Cdc48 p97; intramembrane proteolysis; rhomboid; SREBP; ubiquitin

Indexed keywords

CDC48 PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP; PROTEINASE; RBD2 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; CELL CYCLE PROTEIN; SCHIZOSACCHAROMYCES POMBE PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 84988369511     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201693923     Document Type: Article
Times cited : (37)

References (54)
  • 1
    • 33750465167 scopus 로고    scopus 로고
    • Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria
    • Baker RP, Wijetilaka R, Urban S (2006) Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria. PLoS Pathog 2: e113
    • (2006) PLoS Pathog , vol.2
    • Baker, R.P.1    Wijetilaka, R.2    Urban, S.3
  • 2
    • 84865328335 scopus 로고    scopus 로고
    • Architectural and thermodynamic principles underlying intramembrane protease function
    • Baker RP, Urban S (2012) Architectural and thermodynamic principles underlying intramembrane protease function. Nat Chem Biol 8: 759–768
    • (2012) Nat Chem Biol , vol.8 , pp. 759-768
    • Baker, R.P.1    Urban, S.2
  • 3
    • 84959508424 scopus 로고    scopus 로고
    • The signal peptide peptidase SppA is involved in sterol regulatory element-binding protein cleavage and hypoxia adaptation in Aspergillus nidulans
    • Bat-Ochir C, Kwak JY, Koh SK, Jeon MH, Chung D, Lee YW, Chae SK (2016) The signal peptide peptidase SppA is involved in sterol regulatory element-binding protein cleavage and hypoxia adaptation in Aspergillus nidulans. Mol Microbiol 100: 635–655
    • (2016) Mol Microbiol , vol.100 , pp. 635-655
    • Bat-Ochir, C.1    Kwak, J.Y.2    Koh, S.K.3    Jeon, M.H.4    Chung, D.5    Lee, Y.W.6    Chae, S.K.7
  • 4
    • 45349108992 scopus 로고    scopus 로고
    • An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion
    • Baxt LA, Baker RP, Singh U, Urban S (2008) An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion. Genes Dev 22: 1636–1646
    • (2008) Genes Dev , vol.22 , pp. 1636-1646
    • Baxt, L.A.1    Baker, R.P.2    Singh, U.3    Urban, S.4
  • 5
    • 84885179066 scopus 로고    scopus 로고
    • Emerging role of rhomboid family proteins in mammalian biology and disease
    • Bergbold N, Lemberg MK (2013) Emerging role of rhomboid family proteins in mammalian biology and disease. Biochim Biophys Acta 1828: 2840–2848
    • (2013) Biochim Biophys Acta , vol.1828 , pp. 2840-2848
    • Bergbold, N.1    Lemberg, M.K.2
  • 6
    • 77649296829 scopus 로고    scopus 로고
    • Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis
    • Bien CM, Espenshade PJ (2010) Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis. Eukaryot Cell 9: 352–359
    • (2010) Eukaryot Cell , vol.9 , pp. 352-359
    • Bien, C.M.1    Espenshade, P.J.2
  • 7
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
    • Brown MS, Ye J, Rawson RB, Goldstein JL (2000) Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 100: 391–398
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 8
    • 34247547435 scopus 로고    scopus 로고
    • Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans
    • Chang YC, Bien CM, Lee H, Espenshade PJ, Kwon-Chung KJ (2007) Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans. Mol Microbiol 64: 614–629
    • (2007) Mol Microbiol , vol.64 , pp. 614-629
    • Chang, Y.C.1    Bien, C.M.2    Lee, H.3    Espenshade, P.J.4    Kwon-Chung, K.J.5
  • 9
    • 72449173927 scopus 로고    scopus 로고
    • Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans
    • Chang YC, Ingavale SS, Bien C, Espenshade P, Kwon-Chung KJ (2009) Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans. Eukaryot Cell 8: 1770–1779
    • (2009) Eukaryot Cell , vol.8 , pp. 1770-1779
    • Chang, Y.C.1    Ingavale, S.S.2    Bien, C.3    Espenshade, P.4    Kwon-Chung, K.J.5
  • 10
    • 84880056038 scopus 로고    scopus 로고
    • Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast
    • Cheung R, Espenshade PJ (2013) Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast. J Biol Chem 288: 20351–20360
    • (2013) J Biol Chem , vol.288 , pp. 20351-20360
    • Cheung, R.1    Espenshade, P.J.2
  • 11
    • 33847335459 scopus 로고    scopus 로고
    • A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans
    • Chun CD, Liu OW, Madhani HD (2007) A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans. PLoS Pathog 3: e22
    • (2007) PLoS Pathog , vol.3
    • Chun, C.D.1    Liu, O.W.2    Madhani, H.D.3
  • 13
    • 84890087383 scopus 로고    scopus 로고
    • Proteolysis inside the membrane is a rate-governed reaction not driven by substrate affinity
    • Dickey SW, Baker RP, Cho S, Urban S (2013) Proteolysis inside the membrane is a rate-governed reaction not driven by substrate affinity. Cell 155: 1270–1281
    • (2013) Cell , vol.155 , pp. 1270-1281
    • Dickey, S.W.1    Baker, R.P.2    Cho, S.3    Urban, S.4
  • 15
    • 39849102805 scopus 로고    scopus 로고
    • Regulation of sterol synthesis in eukaryotes
    • Espenshade PJ, Hughes AL (2007) Regulation of sterol synthesis in eukaryotes. Annu Rev Genet 41: 401–427
    • (2007) Annu Rev Genet , vol.41 , pp. 401-427
    • Espenshade, P.J.1    Hughes, A.L.2
  • 16
    • 84865389259 scopus 로고    scopus 로고
    • Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins
    • Fleig L, Bergbold N, Sahasrabudhe P, Geiger B, Kaltak L, Lemberg MK (2012) Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins. Mol Cell 47: 558–569
    • (2012) Mol Cell , vol.47 , pp. 558-569
    • Fleig, L.1    Bergbold, N.2    Sahasrabudhe, P.3    Geiger, B.4    Kaltak, L.5    Lemberg, M.K.6
  • 18
    • 0029911724 scopus 로고    scopus 로고
    • A conditional lethal mutant in the fission yeast 26 S protease subunit mts3+ is defective in metaphase to anaphase transition
    • Gordon C, McGurk G, Wallace M, Hastie ND (1996) A conditional lethal mutant in the fission yeast 26 S protease subunit mts3+ is defective in metaphase to anaphase transition. J Biol Chem 271: 5704–5711
    • (1996) J Biol Chem , vol.271 , pp. 5704-5711
    • Gordon, C.1    McGurk, G.2    Wallace, M.3    Hastie, N.D.4
  • 20
    • 63649088506 scopus 로고    scopus 로고
    • Structure and mechanism of intramembrane protease
    • Ha Y (2009) Structure and mechanism of intramembrane protease. Semin Cell Dev Biol 20: 240–250
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 240-250
    • Ha, Y.1
  • 21
    • 17644401005 scopus 로고    scopus 로고
    • SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast
    • Hughes AL, Todd BL, Espenshade PJ (2005) SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell 120: 831–842
    • (2005) Cell , vol.120 , pp. 831-842
    • Hughes, A.L.1    Todd, B.L.2    Espenshade, P.J.3
  • 23
    • 84993222812 scopus 로고    scopus 로고
    • Proximity-dependent biotin labeling in yeast using the engineered ascorbate peroxidase APEX2
    • Hwang J, Espenshade PJ (2016) Proximity-dependent biotin labeling in yeast using the engineered ascorbate peroxidase APEX2. Biochem J 473: 2463–2469
    • (2016) Biochem J , vol.473 , pp. 2463-2469
    • Hwang, J.1    Espenshade, P.J.2
  • 25
    • 84949624401 scopus 로고    scopus 로고
    • Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast
    • Kim J, Ha HJ, Kim S, Choi AR, Lee SJ, Hoe KL, Kim DU (2015) Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast. Biochem Biophys Res Commun 468: 606–610
    • (2015) Biochem Biophys Res Commun , vol.468 , pp. 606-610
    • Kim, J.1    Ha, H.J.2    Kim, S.3    Choi, A.R.4    Lee, S.J.5    Hoe, K.L.6    Kim, D.U.7
  • 27
    • 0034811675 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor Cph2 regulates hyphal development in Candida albicans partly via Tec1
    • Lane S, Zhou S, Pan T, Dai Q, Liu HP (2001) The basic helix-loop-helix transcription factor Cph2 regulates hyphal development in Candida albicans partly via Tec1. Mol Cell Biol 21: 6418–6428
    • (2001) Mol Cell Biol , vol.21 , pp. 6418-6428
    • Lane, S.1    Zhou, S.2    Pan, T.3    Dai, Q.4    Liu, H.P.5
  • 28
    • 84876806705 scopus 로고    scopus 로고
    • Sampling the membrane: function of rhomboid-family proteins
    • Lemberg MK (2013) Sampling the membrane: function of rhomboid-family proteins. Trends Cell Biol 23: 210–217
    • (2013) Trends Cell Biol , vol.23 , pp. 210-217
    • Lemberg, M.K.1
  • 29
    • 84923677391 scopus 로고    scopus 로고
    • A novel sterol regulatory element-binding protein gene (sreA) identified in penicillium digitatum is required for prochloraz resistance, full virulence and erg11 (cyp51) regulation
    • Liu J, Yuan Y, Wu Z, Li N, Chen Y, Qin T, Geng H, Xiong L, Liu D (2015) A novel sterol regulatory element-binding protein gene (sreA) identified in penicillium digitatum is required for prochloraz resistance, full virulence and erg11 (cyp51) regulation. PLoS One 10: e0117115
    • (2015) PLoS One , vol.10
    • Liu, J.1    Yuan, Y.2    Wu, Z.3    Li, N.4    Chen, Y.5    Qin, T.6    Geng, H.7    Xiong, L.8    Liu, D.9
  • 30
    • 84880519236 scopus 로고    scopus 로고
    • Subunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast
    • Lloyd SJ, Raychaudhuri S, Espenshade PJ (2013) Subunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast. J Biol Chem 288: 21043–21054
    • (2013) J Biol Chem , vol.288 , pp. 21043-21054
    • Lloyd, S.J.1    Raychaudhuri, S.2    Espenshade, P.J.3
  • 32
    • 84878843045 scopus 로고    scopus 로고
    • Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics
    • Moin SM, Urban S (2012) Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics. eLife 1: e00173
    • (2012) eLife , vol.1
    • Moin, S.M.1    Urban, S.2
  • 34
    • 84885181836 scopus 로고    scopus 로고
    • Role of rhomboid proteases in bacteria
    • Rather P (2013) Role of rhomboid proteases in bacteria. Biochim Biophys Acta 1828: 2849–2854
    • (2013) Biochim Biophys Acta , vol.1828 , pp. 2849-2854
    • Rather, P.1
  • 35
    • 84930623337 scopus 로고    scopus 로고
    • Endoplasmic reticulum exit of golgi-resident defective for SREBP cleavage (Dsc) E3 ligase complex requires its activity
    • Raychaudhuri S, Espenshade PJ (2015) Endoplasmic reticulum exit of golgi-resident defective for SREBP cleavage (Dsc) E3 ligase complex requires its activity. J Biol Chem 290: 14430–14440
    • (2015) J Biol Chem , vol.290 , pp. 14430-14440
    • Raychaudhuri, S.1    Espenshade, P.J.2
  • 36
    • 84874956967 scopus 로고    scopus 로고
    • Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging
    • Rhee HW, Zou P, Udeshi ND, Martell JD, Mootha VK, Carr SA, Ting AY (2013) Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging. Science 339: 1328–1331
    • (2013) Science , vol.339 , pp. 1328-1331
    • Rhee, H.W.1    Zou, P.2    Udeshi, N.D.3    Martell, J.D.4    Mootha, V.K.5    Carr, S.A.6    Ting, A.Y.7
  • 37
    • 34447097834 scopus 로고    scopus 로고
    • Sequential E2s drive polyubiquitin chain assembly on APC targets
    • Rodrigo-Brenni MC, Morgan DO (2007) Sequential E2s drive polyubiquitin chain assembly on APC targets. Cell 130: 127–139
    • (2007) Cell , vol.130 , pp. 127-139
    • Rodrigo-Brenni, M.C.1    Morgan, D.O.2
  • 38
    • 33751560802 scopus 로고    scopus 로고
    • Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis
    • Sato BK, Hampton RY (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23: 1053–1064
    • (2006) Yeast , vol.23 , pp. 1053-1064
    • Sato, B.K.1    Hampton, R.Y.2
  • 39
    • 0037965786 scopus 로고    scopus 로고
    • Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin
    • Seino H, Kishi T, Nishitani H, Yamao F (2003) Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin. Mol Cell Biol 23: 3497–3505
    • (2003) Mol Cell Biol , vol.23 , pp. 3497-3505
    • Seino, H.1    Kishi, T.2    Nishitani, H.3    Yamao, F.4
  • 40
    • 84867099976 scopus 로고    scopus 로고
    • Expanding roles for SREBP in metabolism
    • Shao W, Espenshade PJ (2012) Expanding roles for SREBP in metabolism. Cell Metab 16: 414–419
    • (2012) Cell Metab , vol.16 , pp. 414-419
    • Shao, W.1    Espenshade, P.J.2
  • 41
    • 84896264243 scopus 로고    scopus 로고
    • Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP)
    • Shao W, Espenshade PJ (2014) Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP). J Biol Chem 289: 7547–7557
    • (2014) J Biol Chem , vol.289 , pp. 7547-7557
    • Shao, W.1    Espenshade, P.J.2
  • 43
    • 84855288996 scopus 로고    scopus 로고
    • Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase
    • Stewart EV, Lloyd SJ, Burg JS, Nwosu CC, Lintner RE, Daza R, Russ C, Ponchner K, Nusbaum C, Espenshade PJ (2012) Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase. J Biol Chem 287: 672–681
    • (2012) J Biol Chem , vol.287 , pp. 672-681
    • Stewart, E.V.1    Lloyd, S.J.2    Burg, J.S.3    Nwosu, C.C.4    Lintner, R.E.5    Daza, R.6    Russ, C.7    Ponchner, K.8    Nusbaum, C.9    Espenshade, P.J.10
  • 45
    • 72149124813 scopus 로고    scopus 로고
    • Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates
    • Strisovsky K, Sharpe HJ, Freeman M (2009) Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates. Mol Cell 36: 1048–1059
    • (2009) Mol Cell , vol.36 , pp. 1048-1059
    • Strisovsky, K.1    Sharpe, H.J.2    Freeman, M.3
  • 46
    • 33645222762 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast
    • Todd BL, Stewart EV, Burg JS, Hughes AL, Espenshade PJ (2006) Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast. Mol Cell Biol 26: 2817–2831
    • (2006) Mol Cell Biol , vol.26 , pp. 2817-2831
    • Todd, B.L.1    Stewart, E.V.2    Burg, J.S.3    Hughes, A.L.4    Espenshade, P.J.5
  • 47
    • 0038771224 scopus 로고    scopus 로고
    • Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
    • Urban S, Freeman M (2003) Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Mol Cell 11: 1425–1434
    • (2003) Mol Cell , vol.11 , pp. 1425-1434
    • Urban, S.1    Freeman, M.2
  • 48
    • 33751246749 scopus 로고    scopus 로고
    • Rhomboid proteins: conserved membrane proteases with divergent biological functions
    • Urban S (2006) Rhomboid proteins: conserved membrane proteases with divergent biological functions. Genes Dev 20: 3054–3068
    • (2006) Genes Dev , vol.20 , pp. 3054-3068
    • Urban, S.1
  • 49
    • 50849109498 scopus 로고    scopus 로고
    • In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells
    • Urban S, Baker RP (2008) In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells. Biol Chem 389: 1107–1115
    • (2008) Biol Chem , vol.389 , pp. 1107-1115
    • Urban, S.1    Baker, R.P.2
  • 50
    • 49549106231 scopus 로고    scopus 로고
    • Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases
    • Urban S, Shi Y (2008) Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases. Curr Opin Struct Biol 18: 432–441
    • (2008) Curr Opin Struct Biol , vol.18 , pp. 432-441
    • Urban, S.1    Shi, Y.2
  • 51
    • 74349127184 scopus 로고    scopus 로고
    • Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis
    • Urban S (2010) Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis. Biochem J 425: 501–512
    • (2010) Biochem J , vol.425 , pp. 501-512
    • Urban, S.1
  • 52
    • 80054893675 scopus 로고    scopus 로고
    • The rhomboid protease family: a decade of progress on function and mechanism
    • Urban S, Dickey SW (2011) The rhomboid protease family: a decade of progress on function and mechanism. Genome Biol 12: 231
    • (2011) Genome Biol , vol.12 , pp. 231
    • Urban, S.1    Dickey, S.W.2


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