-
1
-
-
0027176294
-
The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway
-
M.A. Sturtevant, M. Roark, and E. Bier The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway Genes Dev. 7 1993 961 973 (Pubitemid 23170821)
-
(1993)
Genes and Development
, vol.7
, Issue.6
, pp. 961-973
-
-
Sturtevant, M.A.1
Roark, M.2
Bier, E.3
-
2
-
-
0028059268
-
The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor
-
DOI 10.1016/0925-4773(94)90003-5
-
M. Freeman The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor Mech. Dev. 48 1994 25 33 (Pubitemid 24294319)
-
(1994)
Mechanisms of Development
, vol.48
, Issue.1
, pp. 25-33
-
-
Freeman, M.1
-
3
-
-
0035913906
-
Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila
-
DOI 10.1016/S0092-8674(01)00526-8
-
J.R. Lee, S. Urban, C.F. Garvey, and M. Freeman Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila Cell 107 2001 161 171 (Pubitemid 33035943)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 161-171
-
-
Lee, J.R.1
Urban, S.2
Garvey, C.F.3
Freeman, M.4
-
4
-
-
0035913908
-
Drosophila Rhomboid-1 defines a family of putative intramembrane serine proteases
-
DOI 10.1016/S0092-8674(01)00525-6
-
S. Urban, J.R. Lee, and M. Freeman Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases Cell 107 2001 173 182 (Pubitemid 33035944)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 173-182
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
5
-
-
0037102238
-
A family of rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands
-
S. Urban, J.R. Lee, and M. Freeman A family of rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands EMBO J. 21 2002 4277 4286
-
(2002)
EMBO J.
, vol.21
, pp. 4277-4286
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
6
-
-
84885100166
-
The mitochondrial rhomboid: Its rise from obscurity to the pinnacle of disease-relevant genes
-
Y.L. Chan, and G.A. McQuibban The mitochondrial rhomboid: its rise from obscurity to the pinnacle of disease-relevant genes Biochim. Biophys. Acta 1828 2013 2916 2925
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 2916-2925
-
-
Chan, Y.L.1
McQuibban, G.A.2
-
7
-
-
84885181836
-
Role of rhomboid proteases in bacteria
-
P. Rather Role of rhomboid proteases in bacteria Biochim. Biophys. Acta 1828 2013 2849 2854
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 2849-2854
-
-
Rather, P.1
-
8
-
-
84885117774
-
The roles of intramembrane proteases in protozan parasites
-
D.L. Sibley The roles of intramembrane proteases in protozan parasites Biochim. Biophys. Acta 1828 2013 2908 2915
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 2908-2915
-
-
Sibley, D.L.1
-
9
-
-
0036424840
-
A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1
-
DOI 10.1016/S0022-2836(02)01000-8
-
K. Esser, B. Tursun, M. Ingenhoven, G. Michaelis, and E. Pratje A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1 J. Mol. Biol. 323 2002 835 843 (Pubitemid 35345133)
-
(2002)
Journal of Molecular Biology
, vol.323
, Issue.5
, pp. 835-843
-
-
Esser, K.1
Tursun, B.2
Ingenhoven, M.3
Michaelis, G.4
Pratje, E.5
-
10
-
-
0037015265
-
Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids
-
DOI 10.1016/S0960-9822(02)01092-8, PII S0960982202010928
-
S. Urban, D. Schlieper, and M. Freeman Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids Curr. Biol. 12 2002 1507 1512 (Pubitemid 35036649)
-
(2002)
Current Biology
, vol.12
, Issue.17
, pp. 1507-1512
-
-
Urban, S.1
Schlieper, D.2
Freeman, M.3
-
11
-
-
13844306483
-
Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity
-
DOI 10.1073/pnas.0408306102
-
S. Urban, and M.S. Wolfe Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity Proc. Natl. Acad. Sci. USA 102 2005 1883 1888 (Pubitemid 40261981)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.6
, pp. 1883-1888
-
-
Urban, S.1
Wolfe, M.S.2
-
12
-
-
14844300797
-
Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases
-
DOI 10.1038/sj.emboj.7600537
-
M.K. Lemberg, J. Menendez, A. Misik, M. Garcia, C.M. Koth, and M. Freeman Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases EMBO J. 24 2005 464 472 (Pubitemid 40343249)
-
(2005)
EMBO Journal
, vol.24
, Issue.3
, pp. 464-472
-
-
Lemberg, M.K.1
Menendez, J.2
Misik, A.3
Garcia, M.4
Koth, C.M.5
Freeman, M.6
-
13
-
-
84885161299
-
Untangling structure-function relationships in the rhomboid family of intramembrane proteases
-
C.L. Brooks, and M.J. Lemieux Untangling structure-function relationships in the rhomboid family of intramembrane proteases Biochim. Biophys. Acta 1828 2013 2862 2872
-
(2013)
Biochim. Biophys. Acta
, vol.1828
, pp. 2862-2872
-
-
Brooks, C.L.1
Lemieux, M.J.2
-
14
-
-
33750886311
-
Crystal structure of a rhomboid family intramembrane protease
-
Y. Wang, Y. Zhang, and Y. Ha Crystal structure of a rhomboid family intramembrane protease Nature 444 2006 179 180
-
(2006)
Nature
, vol.444
, pp. 179-180
-
-
Wang, Y.1
Zhang, Y.2
Ha, Y.3
-
15
-
-
35948982252
-
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases
-
DOI 10.1101/gr.6425307
-
M.K. Lemberg, and M. Freeman Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases Genome Res. 17 2007 1634 1646 (Pubitemid 350074859)
-
(2007)
Genome Research
, vol.17
, Issue.11
, pp. 1634-1646
-
-
Lemberg, M.K.1
Freeman, M.2
-
16
-
-
80455164551
-
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant alpha-1 antitrypsin from the endoplasmic reticulum
-
E.J. Greenblatt, J.A. Olzmann, and R.R. Kopito Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant alpha-1 antitrypsin from the endoplasmic reticulum Nat. Struct. Mol. Biol. 18 2011 1147 1152
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1147-1152
-
-
Greenblatt, E.J.1
Olzmann, J.A.2
Kopito, R.R.3
-
17
-
-
0037264371
-
The rhomboids: A nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers
-
E.V. Koonin, K.S. Makarova, I.B. Rogozin, L. Davidovic, M.C. Letellier, and L. Pellegrini The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers Genome Biol. 4 2003 R19
-
(2003)
Genome Biol.
, vol.4
, pp. 19
-
-
Koonin, E.V.1
Makarova, K.S.2
Rogozin, I.B.3
Davidovic, L.4
Letellier, M.C.5
Pellegrini, L.6
-
18
-
-
75549090603
-
The Pfam protein families database
-
R.D. Finn, J. Mistry, J. Tate, P. Coggill, A. Heger, J.E. Pollington, O.L. Gavin, P. Gunasekaran, G. Ceric, K. Forslund, L. Holm, E.L. Sonnhammer, S.R. Eddy, and A. Bateman The Pfam protein families database Nucleic Acids Res. 38 2010 D211 D222
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Finn, R.D.1
Mistry, J.2
Tate, J.3
Coggill, P.4
Heger, A.5
Pollington, J.E.6
Gavin, O.L.7
Gunasekaran, P.8
Ceric, G.9
Forslund, K.10
Holm, L.11
Sonnhammer, E.L.12
Eddy, S.R.13
Bateman, A.14
-
19
-
-
84864279894
-
New lives for old: Evolution of pseudoenzyme function illustrated by iRhoms
-
C. Adrain, and M. Freeman New lives for old: evolution of pseudoenzyme function illustrated by iRhoms Nat. Rev. Mol. Cell Biol. 13 2012 489 498
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 489-498
-
-
Adrain, C.1
Freeman, M.2
-
20
-
-
84865328335
-
Architectural and thermodynamic principles underlying intramembrane protease function
-
R.P. Baker, and S. Urban Architectural and thermodynamic principles underlying intramembrane protease function Nat. Chem. Biol. 8 2012 759 768
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 759-768
-
-
Baker, R.P.1
Urban, S.2
-
21
-
-
33845343261
-
Membrane-protein topology
-
DOI 10.1038/nrm2063, PII NRM2063
-
G. von Heijne Membrane-protein topology Nat. Rev. Mol. Cell Biol. 7 2006 909 918 (Pubitemid 44871417)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.12
, pp. 909-918
-
-
Von Heijne, G.1
-
22
-
-
0032537494
-
Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid
-
DOI 10.1016/S0014-5793(98)00622-X, PII S001457939800622X
-
J.C. Pascall, and K.D. Brown Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein rhomboid FEBS Lett. 429 1998 337 340 (Pubitemid 28300387)
-
(1998)
FEBS Letters
, vol.429
, Issue.3
, pp. 337-340
-
-
Pascall, J.C.1
Brown, K.D.2
-
23
-
-
1242288387
-
Diverse substrate recognition mechanisms for rhomboids: Thrombomodulin is cleaved by mammalian rhomboids
-
DOI 10.1016/S0960-9822(04)00008-9
-
O. Lohi, S. Urban, and M. Freeman Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboids Curr. Biol. 14 2004 236 241 (Pubitemid 38215352)
-
(2004)
Current Biology
, vol.14
, Issue.3
, pp. 236-241
-
-
Lohi, O.1
Urban, S.2
Freeman, M.3
-
24
-
-
57349136681
-
A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis
-
Y. Wang, X. Guan, K.L. Fok, S. Li, X. Zhang, S. Miao, S. Zong, S.S. Koide, H.C. Chan, and L. Wang A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis Cell. Mol. Life Sci. 65 2008 3822 3829
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 3822-3829
-
-
Wang, Y.1
Guan, X.2
Fok, K.L.3
Li, S.4
Zhang, X.5
Miao, S.6
Zong, S.7
Koide, S.S.8
Chan, H.C.9
Wang, L.10
-
25
-
-
84865389259
-
Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins
-
L. Fleig, N. Bergbold, P. Sahasrabudhe, B. Geiger, L. Kaltak, and M.K. Lemberg Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins Mol. Cell 47 2012 558 569
-
(2012)
Mol. Cell
, vol.47
, pp. 558-569
-
-
Fleig, L.1
Bergbold, N.2
Sahasrabudhe, P.3
Geiger, B.4
Kaltak, L.5
Lemberg, M.K.6
-
26
-
-
0038700756
-
Mitochondrial membrane remodelling regulated by a conserved rhomboid protease
-
DOI 10.1038/nature01633
-
G.A. McQuibban, S. Saurya, and M. Freeman Mitochondrial membrane remodelling regulated by a conserved rhomboid protease Nature 423 2003 537 541 (Pubitemid 36648577)
-
(2003)
Nature
, vol.423
, Issue.6939
, pp. 537-541
-
-
McQuibban, G.A.1
Saurya, S.2
Freeman, M.3
-
27
-
-
33845472429
-
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology
-
DOI 10.1073/pnas.0604983103
-
D.V. Jeyaraju, L. Xu, M.C. Letellier, S. Bandaru, R. Zunino, E.A. Berg, H.M. McBride, and L. Pellegrini Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology Proc. Natl. Acad. Sci. USA 103 2006 18562 18567 (Pubitemid 44913450)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.49
, pp. 18562-18567
-
-
Jeyaraju, D.V.1
Xu, L.2
Letellier, M.-C.3
Bandaru, S.4
Zunino, R.5
Berg, E.A.6
McBride, H.M.7
Pellegrini, L.8
-
28
-
-
33947178517
-
Rhomboid cleaves Star to regulate the levels of secreted Spitz
-
DOI 10.1038/sj.emboj.7601581, PII 7601581
-
R. Tsruya, A. Wojtalla, S. Carmon, S. Yogev, A. Reich, E. Bibi, G. Merdes, E. Schejter, and B.Z. Shilo Rhomboid cleaves Star to regulate the levels of secreted Spitz EMBO J. 26 2007 1211 1220 (Pubitemid 46398704)
-
(2007)
EMBO Journal
, vol.26
, Issue.5
, pp. 1211-1220
-
-
Tsruya, R.1
Wojtalla, A.2
Carmon, S.3
Yogev, S.4
Reich, A.5
Bibi, E.6
Merdes, G.7
Schejter, E.8
Shilo, B.-Z.9
-
29
-
-
73149105938
-
Cleavage of a multispanning membrane protein by an intramembrane serine protease
-
E. Erez, and E. Bibi Cleavage of a multispanning membrane protein by an intramembrane serine protease Biochemistry 48 2009 12314 12322
-
(2009)
Biochemistry
, vol.48
, pp. 12314-12322
-
-
Erez, E.1
Bibi, E.2
-
30
-
-
84862064898
-
Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis
-
C. Wan, J. Fu, Y. Wang, S. Miao, W. Song, and L. Wang Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis PLoS One 7 2012 e37452
-
(2012)
PLoS One
, vol.7
, pp. 37452
-
-
Wan, C.1
Fu, J.2
Wang, Y.3
Miao, S.4
Song, W.5
Wang, L.6
-
31
-
-
70449642213
-
The processing of human rhomboid intramembrane serine protease RHBDL2 is required for its proteolytic activity
-
X. Lei, and Y.M. Li The processing of human rhomboid intramembrane serine protease RHBDL2 is required for its proteolytic activity J. Mol. Biol. 394 2009 815 825
-
(2009)
J. Mol. Biol.
, vol.394
, pp. 815-825
-
-
Lei, X.1
Li, Y.M.2
-
32
-
-
80051669175
-
Intramembrane proteolysis in regulated protein trafficking
-
M.K. Lemberg Intramembrane proteolysis in regulated protein trafficking Traffic 12 2011 1109 1118
-
(2011)
Traffic
, vol.12
, pp. 1109-1118
-
-
Lemberg, M.K.1
-
33
-
-
74349127184
-
Taking the plunge: Integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis
-
S. Urban Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis Biochem. J. 425 2010 501 512
-
(2010)
Biochem. J.
, vol.425
, pp. 501-512
-
-
Urban, S.1
-
34
-
-
0038771224
-
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
-
S. Urban, and M. Freeman Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain Mol. Cell 11 2003 1425-1134
-
(2003)
Mol. Cell
, vol.11
, pp. 1425-1134
-
-
Urban, S.1
Freeman, M.2
-
35
-
-
84878843045
-
Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics
-
S.M. Moin, and S. Urban Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics Elife 1 2012 e00173
-
(2012)
Elife
, vol.1
, pp. 00173
-
-
Moin, S.M.1
Urban, S.2
-
36
-
-
34248371981
-
Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease
-
DOI 10.1111/j.1365-2958.2007.05715.x
-
Y. Akiyama, and S. Maegawa Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease Mol. Microbiol. 64 2007 1028 1037 (Pubitemid 46743969)
-
(2007)
Molecular Microbiology
, vol.64
, Issue.4
, pp. 1028-1037
-
-
Akiyama, Y.1
Maegawa, S.2
-
37
-
-
72149124813
-
Sequence-specific intramembrane proteolysis: Identification of a recognition motif in rhomboid substrates
-
K. Strisovsky, H.J. Sharpe, and M. Freeman Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates Mol. Cell 36 2009 1048 1059
-
(2009)
Mol. Cell
, vol.36
, pp. 1048-1059
-
-
Strisovsky, K.1
Sharpe, H.J.2
Freeman, M.3
-
38
-
-
79951807624
-
The link between vascular features and thrombosis
-
C.T. Esmon, and N.L. Esmon The link between vascular features and thrombosis Annu. Rev. Physiol. 73 2011 503 514
-
(2011)
Annu. Rev. Physiol.
, vol.73
, pp. 503-514
-
-
Esmon, C.T.1
Esmon, N.L.2
-
39
-
-
84864741032
-
Thrombomodulin is an ezrin-interacting protein that controls epithelial morphology and promotes collective cell migration
-
Y.Y. Hsu, G.Y. Shi, C.H. Kuo, S.L. Liu, C.M. Wu, C.Y. Ma, F.Y. Lin, H.Y. Yang, and H.L. Wu Thrombomodulin is an ezrin-interacting protein that controls epithelial morphology and promotes collective cell migration FASEB J. 26 2012 3440 3452
-
(2012)
FASEB J.
, vol.26
, pp. 3440-3452
-
-
Hsu, Y.Y.1
Shi, G.Y.2
Kuo, C.H.3
Liu, S.L.4
Wu, C.M.5
Ma, C.Y.6
Lin, F.Y.7
Yang, H.Y.8
Wu, H.L.9
-
40
-
-
0028211896
-
Purification and characterization of two forms of soluble thrombomodulin from human urine
-
D.E. Jackson, T.J. Tetaz, H.H. Salem, and C.A. Mitchell Purification and characterization of two forms of soluble thrombomodulin from human urine Eur. J. Biochem. 221 1994 1079 1087 (Pubitemid 24146211)
-
(1994)
European Journal of Biochemistry
, vol.221
, Issue.3
, pp. 1079-1087
-
-
Jackson, D.E.1
Tetaz, T.J.2
Salem, H.H.3
Mitchell, C.A.4
-
41
-
-
80855138090
-
Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing
-
T.L. Cheng, Y.T. Wu, H.Y. Lin, F.C. Hsu, S.K. Liu, B.I. Chang, W.S. Chen, C.H. Lai, G.Y. Shi, and H.L. Wu Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing J. Invest. Dermatol. 131 2011 2486 2494
-
(2011)
J. Invest. Dermatol.
, vol.131
, pp. 2486-2494
-
-
Cheng, T.L.1
Wu, Y.T.2
Lin, H.Y.3
Hsu, F.C.4
Liu, S.K.5
Chang, B.I.6
Chen, W.S.7
Lai, C.H.8
Shi, G.Y.9
Wu, H.L.10
-
42
-
-
20244382267
-
Evidence of human thrombomodulin domain as a novel angiogenic factor
-
DOI 10.1161/01.CIR.0000160364.05405.B5
-
C.S. Shi, G.Y. Shi, Y.S. Chang, H.S. Han, C.H. Kuo, C. Liu, H.C. Huang, Y.J. Chang, P.S. Chen, and H.L. Wu Evidence of human thrombomodulin domain as a novel angiogenic factor Circulation 111 2005 1627 1636 (Pubitemid 40525162)
-
(2005)
Circulation
, vol.111
, Issue.13
, pp. 1627-1636
-
-
Shi, C.-S.1
Shi, G.-Y.2
Chang, Y.-S.3
Han, H.-S.4
Kuo, C.-H.5
Liu, C.6
Huang, H.-C.7
Chang, Y.-J.8
Chen, P.-S.9
Wu, H.-L.10
-
43
-
-
1642422313
-
Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2
-
DOI 10.1016/j.bbrc.2004.03.039, PII S0006291X04005339
-
J.C. Pascall, and K.D. Brown Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2 Biochem. Biophys. Res. Commun. 317 2004 244 252 (Pubitemid 38401991)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.317
, Issue.1
, pp. 244-252
-
-
Pascall, J.C.1
Brown, K.D.2
-
44
-
-
39449085234
-
Eph/ephrin signaling: Networks
-
DOI 10.1101/gad.1630408
-
D. Arvanitis, and A. Davy Eph/ephrin signaling: networks Genes Dev. 22 2008 416 429 (Pubitemid 351272750)
-
(2008)
Genes and Development
, vol.22
, Issue.4
, pp. 416-429
-
-
Arvanitis, D.1
Davy, A.2
-
45
-
-
0034714357
-
Regulated cleavage of a contact-mediated axon repellent
-
DOI 10.1126/science.289.5483.1360
-
M. Hattori, M. Osterfield, and J.G. Flanagan Regulated cleavage of a contact-mediated axon repellent Science 289 2000 1360 1365 (Pubitemid 30656055)
-
(2000)
Science
, vol.289
, Issue.5483
, pp. 1360-1365
-
-
Hattori, M.1
Osterfield, M.2
Flanagan, J.G.3
-
46
-
-
34447538273
-
The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells
-
DOI 10.1242/jcs.008607
-
M. Tanaka, K. Sasaki, R. Kamata, and R. Sakai The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells J. Cell Sci. 120 2007 2179 2189 (Pubitemid 47074123)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.13
, pp. 2179-2189
-
-
Tanaka, M.1
Sasaki, K.2
Kamata, R.3
Sakai, R.4
-
47
-
-
57649221000
-
Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion
-
K.T. Lin, S. Sloniowski, D.W. Ethell, and I.M. Ethell Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion J. Biol. Chem. 283 2008 28969 28979
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28969-28979
-
-
Lin, K.T.1
Sloniowski, S.2
Ethell, D.W.3
Ethell, I.M.4
-
48
-
-
79955470772
-
The "a Disintegrin and Metalloproteases" ADAM10 and ADAM17: Novel drug targets with therapeutic potential?
-
P. Saftig, and K. Reiss The "A Disintegrin And Metalloproteases" ADAM10 and ADAM17: novel drug targets with therapeutic potential? Eur. J. Cell Biol. 90 2011 527 535
-
(2011)
Eur. J. Cell Biol.
, vol.90
, pp. 527-535
-
-
Saftig, P.1
Reiss, K.2
-
49
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
J.J. Peschon, J.L. Slack, P. Reddy, K.L. Stocking, S.W. Sunnarborg, D.C. Lee, W.E. Russell, B.J. Castner, R.S. Johnson, J.N. Fitzner, R.W. Boyce, N. Nelson, C.J. Kozlosky, M.F. Wolfson, C.T. Rauch, D.P. Cerretti, R.J. Paxton, C.J. March, and R.A. Black An essential role for ectodomain shedding in mammalian development Science 282 1998 1281 1284 (Pubitemid 28524483)
-
(1998)
Science
, vol.282
, Issue.5392
, pp. 1281-1284
-
-
Peschon, J.J.1
Slack, J.L.2
Reddy, P.3
Stocking, K.L.4
Sunnarborg, S.W.5
Lee, D.C.6
Russell, W.E.7
Castner, B.J.8
Johnson, R.S.9
Fitzner, J.N.10
Boyce, R.W.11
Nelson, N.12
Kozlosky, C.J.13
Wolfson, M.F.14
Rauch, C.T.15
Cerretti, D.P.16
Paxton, R.J.17
March, C.J.18
Black, R.A.19
-
50
-
-
1442358746
-
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
-
DOI 10.1083/jcb.200307137
-
U. Sahin, G. Weskamp, K. Kelly, H.M. Zhou, S. Higashiyama, J. Peschon, D. Hartmann, P. Saftig, and C.P. Blobel Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands J. Cell Biol. 164 2004 769 779 (Pubitemid 38282960)
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.5
, pp. 769-779
-
-
Sahin, U.1
Weskamp, G.2
Kelly, K.3
Zhou, H.-M.4
Higashiyama, S.5
Peschon, J.6
Hartmann, D.7
Saftig, P.8
Blobel, C.P.9
-
51
-
-
0027997130
-
Processing of epidermal growth factor in the rat submandibular gland by Kallikrein-like enzymes
-
P.E. Jorgensen, E. Nexo, S.S. Poulsen, M. Almendingen, and T. Berg Processing of epidermal growth factor in the rat submandibular gland by Kallikrein-like enzymes Growth Factors 11 1994 113 123 (Pubitemid 24349715)
-
(1994)
Growth Factors
, vol.11
, Issue.2
, pp. 113-123
-
-
Jorgensen, P.E.1
Nex, E.2
Poulsen, S.S.3
Almendingen, M.4
Berg, T.5
-
52
-
-
79955526700
-
Mammalian EGF receptor activation by the rhomboid protease RHBDL2
-
C. Adrain, K. Strisovsky, M. Zettl, L. Hu, M.K. Lemberg, and M. Freeman Mammalian EGF receptor activation by the rhomboid protease RHBDL2 EMBO Rep. 12 2011 421 427
-
(2011)
EMBO Rep.
, vol.12
, pp. 421-427
-
-
Adrain, C.1
Strisovsky, K.2
Zettl, M.3
Hu, L.4
Lemberg, M.K.5
Freeman, M.6
-
53
-
-
84863868124
-
Regulated intramembrane cleavage of the EGF receptor
-
H.J. Liao, and G. Carpenter Regulated intramembrane cleavage of the EGF receptor Traffic 13 2012 1106 1112
-
(2012)
Traffic
, vol.13
, pp. 1106-1112
-
-
Liao, H.J.1
Carpenter, G.2
-
54
-
-
84858121800
-
The role of ubiquitylation in receptor endocytosis and endosomal sorting
-
K. Haglund, and I. Dikic The role of ubiquitylation in receptor endocytosis and endosomal sorting J. Cell Sci. 125 2012 265 275
-
(2012)
J. Cell Sci.
, vol.125
, pp. 265-275
-
-
Haglund, K.1
Dikic, I.2
-
55
-
-
0030661989
-
Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism
-
DOI 10.1083/jcb.139.4.995
-
M. Vecchi, and G. Carpenter Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism J. Cell Biol. 139 1997 995 1003 (Pubitemid 27508569)
-
(1997)
Journal of Cell Biology
, vol.139
, Issue.4
, pp. 995-1003
-
-
Vecchi, M.1
Carpenter, G.2
-
56
-
-
0034602333
-
Heregulin-dependent trafficking and cleavage of ErbB-4
-
W. Zhou, and G. Carpenter Heregulin-dependent trafficking and cleavage of ErbB-4 J. Biol. Chem. 275 2000 34737 34743
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34737-34743
-
-
Zhou, W.1
Carpenter, G.2
-
57
-
-
0035824391
-
Gamma-secretase cleavage and nuclear locatization of ErbB-4 receptor tyrosine kinase
-
DOI 10.1126/science.1065412
-
C.Y. Ni, M.P. Murphy, T.E. Golde, and G. Carpenter Gamma -secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase Science 294 2001 2179 2181 (Pubitemid 33150677)
-
(2001)
Science
, vol.294
, Issue.5549
, pp. 2179-2181
-
-
Ni, C.-Y.1
Murphy, M.P.2
Golde, T.E.3
Carpenter, G.4
-
58
-
-
33750369213
-
The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice
-
DOI 10.1677/jme.1.02096
-
A. Petri, J. Ahnfelt-Ronne, K.S. Frederiksen, D.G. Edwards, D. Madsen, P. Serup, J. Fleckner, and R.S. Heller The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice J. Mol. Endocrinol. 37 2006 301 316 (Pubitemid 44615300)
-
(2006)
Journal of Molecular Endocrinology
, vol.37
, Issue.2
, pp. 301-316
-
-
Petri, A.1
Ahnfelt-Ronne, J.2
Frederiksen, K.S.3
Edwards, D.G.4
Madsen, D.5
Serup, P.6
Fleckner, J.7
Heller, R.S.8
-
59
-
-
84886717422
-
Age-associated changes in gene expression in human brain and isolated neurons
-
A. Kumar, J.R. Gibbs, A. Beilina, A. Dillman, R. Kumaran, D. Trabzuni, M. Ryten, R. Walker, C. Smith, B.J. Traynor, J. Hardy, A.B. Singleton, and M.R. Cookson Age-associated changes in gene expression in human brain and isolated neurons Neurobiol. Aging 2012
-
(2012)
Neurobiol. Aging
-
-
Kumar, A.1
Gibbs, J.R.2
Beilina, A.3
Dillman, A.4
Kumaran, R.5
Trabzuni, D.6
Ryten, M.7
Walker, R.8
Smith, C.9
Traynor, B.J.10
Hardy, J.11
Singleton, A.B.12
Cookson, M.R.13
-
60
-
-
79959481888
-
Protein folding and modification in the mammalian endoplasmic reticulum
-
I. Braakman, and N.J. Bulleid Protein folding and modification in the mammalian endoplasmic reticulum Annu. Rev. Biochem. 80 2011 71 99
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 71-99
-
-
Braakman, I.1
Bulleid, N.J.2
-
61
-
-
84865298998
-
Finding the will and the way of ERAD substrate retrotranslocation
-
R.Y. Hampton, and T. Sommer Finding the will and the way of ERAD substrate retrotranslocation Curr. Opin. Cell Biol. 24 2012 460 466
-
(2012)
Curr. Opin. Cell Biol.
, vol.24
, pp. 460-466
-
-
Hampton, R.Y.1
Sommer, T.2
-
62
-
-
79953269767
-
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling
-
M. Zettl, C. Adrain, K. Strisovsky, V. Lastun, and M. Freeman Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling Cell 145 2011 79 91
-
(2011)
Cell
, vol.145
, pp. 79-91
-
-
Zettl, M.1
Adrain, C.2
Strisovsky, K.3
Lastun, V.4
Freeman, M.5
-
63
-
-
84867818285
-
A Role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) alpha-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes
-
R.S. Chanthaphavong, P.A. Loughran, T.Y. Lee, M.J. Scott, and T.R. Billiar A Role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) alpha-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes J. Biol. Chem. 287 2012 35887 35898
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 35887-35898
-
-
Chanthaphavong, R.S.1
Loughran, P.A.2
Lee, T.Y.3
Scott, M.J.4
Billiar, T.R.5
-
64
-
-
84862909285
-
IRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
-
D.R. McIlwain, P.A. Lang, T. Maretzky, K. Hamada, K. Ohishi, S.K. Maney, T. Berger, A. Murthy, G. Duncan, H.C. Xu, K.S. Lang, D. Haussinger, A. Wakeham, A. Itie-Youten, R. Khokha, P.S. Ohashi, C.P. Blobel, and T.W. Mak iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS Science 335 2011 229 232
-
(2011)
Science
, vol.335
, pp. 229-232
-
-
McIlwain, D.R.1
Lang, P.A.2
Maretzky, T.3
Hamada, K.4
Ohishi, K.5
Maney, S.K.6
Berger, T.7
Murthy, A.8
Duncan, G.9
Xu, H.C.10
Lang, K.S.11
Haussinger, D.12
Wakeham, A.13
Itie-Youten, A.14
Khokha, R.15
Ohashi, P.S.16
Blobel, C.P.17
Mak, T.W.18
-
65
-
-
84861766061
-
Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer
-
P.M. Wojnarowicz, D.M. Provencher, A.M. Mes-Masson, and P.N. Tonin Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer Int. J. Oncol. 40 2012 1865 1880
-
(2012)
Int. J. Oncol.
, vol.40
, pp. 1865-1880
-
-
Wojnarowicz, P.M.1
Provencher, D.M.2
Mes-Masson, A.M.3
Tonin, P.N.4
-
66
-
-
84857058050
-
RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome
-
D.C. Blaydon, S.L. Etheridge, J.M. Risk, H.C. Hennies, L.J. Gay, R. Carroll, V. Plagnol, F.E. McRonald, H.P. Stevens, N.K. Spurr, D.T. Bishop, A. Ellis, J. Jankowski, J.K. Field, I.M. Leigh, A.P. South, and D.P. Kelsell RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome Am. J. Hum. Genet. 90 2012 340 346
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 340-346
-
-
Blaydon, D.C.1
Etheridge, S.L.2
Risk, J.M.3
Hennies, H.C.4
Gay, L.J.5
Carroll, R.6
Plagnol, V.7
McRonald, F.E.8
Stevens, H.P.9
Spurr, N.K.10
Bishop, D.T.11
Ellis, A.12
Jankowski, J.13
Field, J.K.14
Leigh, I.M.15
South, A.P.16
Kelsell, D.P.17
-
67
-
-
84855822415
-
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
-
C. Adrain, M. Zettl, Y. Christova, N. Taylor, and M. Freeman Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE Science 335 2012 225 228
-
(2012)
Science
, vol.335
, pp. 225-228
-
-
Adrain, C.1
Zettl, M.2
Christova, Y.3
Taylor, N.4
Freeman, M.5
-
68
-
-
84862491782
-
IRhom2 is required for the secretion of mouse TNF alpha
-
O.M. Siggs, N. Xiao, Y. Wang, H. Shi, W. Tomisato, X. Li, Y. Xia, and B. Beutler iRhom2 is required for the secretion of mouse TNF alpha Blood 119 2012 5769 5771
-
(2012)
Blood
, vol.119
, pp. 5769-5771
-
-
Siggs, O.M.1
Xiao, N.2
Wang, Y.3
Shi, H.4
Tomisato, W.5
Li, X.6
Xia, Y.7
Beutler, B.8
-
69
-
-
0038541768
-
Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)
-
DOI 10.1042/0264-6021:3470131
-
J. Schlondorff, J.D. Becherer, and C.P. Blobel Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE) Biochem. J. 347 Pt 1 2000 131 138 (Pubitemid 30199050)
-
(2000)
Biochemical Journal
, vol.347
, Issue.1
, pp. 131-138
-
-
Schlondorff, J.1
Becherer, J.D.2
Blobel, C.P.3
-
70
-
-
84873349403
-
IRHOM2 is a critical pathogenic mediator of inflammatory arthritis
-
P.D. Issuree, T. Maretzky, D.R. McIlwain, S. Monette, X. Qing, P.A. Lang, S.L. Swendeman, K.H. Park-Min, N. Binder, G.D. Kalliolias, A. Yarilina, K. Horiuchi, L.B. Ivashkiv, T.W. Mak, J.E. Salmon, and C.P. Blobel iRHOM2 is a critical pathogenic mediator of inflammatory arthritis J. Clin. Invest. 2013
-
(2013)
J. Clin. Invest.
-
-
Issuree, P.D.1
Maretzky, T.2
McIlwain, D.R.3
Monette, S.4
Qing, X.5
Lang, P.A.6
Swendeman, S.L.7
Park-Min, K.H.8
Binder, N.9
Kalliolias, G.D.10
Yarilina, A.11
Horiuchi, K.12
Ivashkiv, L.B.13
Mak, T.W.14
Salmon, J.E.15
Blobel, C.P.16
-
71
-
-
84876806705
-
Sampling the membrane: Function of rhomboid-family proteins
-
10.1016/j.tcb.2013.01.002
-
M.K. Lemberg Sampling the membrane: function of rhomboid-family proteins Trends Cell Biol. 2013 10.1016/j.tcb.2013.01.002
-
(2013)
Trends Cell Biol.
-
-
Lemberg, M.K.1
-
72
-
-
49849094826
-
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth
-
Z. Yan, H. Zou, F. Tian, J.R. Grandis, A.J. Mixson, P.Y. Lu, and L.Y. Li Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth Mol. Cancer Ther. 7 2008 1355 1364
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1355-1364
-
-
Yan, Z.1
Zou, H.2
Tian, F.3
Grandis, J.R.4
Mixson, A.J.5
Lu, P.Y.6
Li, L.Y.7
-
73
-
-
59649109249
-
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells
-
H. Zou, S.M. Thomas, Z.W. Yan, J.R. Grandis, A. Vogt, and L.Y. Li Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells FASEB J. 23 2009 425 432
-
(2009)
FASEB J.
, vol.23
, pp. 425-432
-
-
Zou, H.1
Thomas, S.M.2
Yan, Z.W.3
Grandis, J.R.4
Vogt, A.5
Li, L.Y.6
-
74
-
-
84864281934
-
Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer
-
S. Saarinen, P. Vahteristo, R. Lehtonen, K. Aittomaki, V. Launonen, T. Kiviluoto, and L.A. Aaltonen Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer Fam. Cancer 11 2012 525 528
-
(2012)
Fam. Cancer
, vol.11
, pp. 525-528
-
-
Saarinen, S.1
Vahteristo, P.2
Lehtonen, R.3
Aittomaki, K.4
Launonen, V.5
Kiviluoto, T.6
Aaltonen, L.A.7
-
75
-
-
22244458854
-
hRho/RHBDF1, which interacts with TGF-alpha family ligands
-
DOI 10.1002/dvdy.20450
-
T. Nakagawa, A. Guichard, C.P. Castro, Y. Xiao, M. Rizen, H.Z. Zhang, D. Hu, A. Bang, J. Helms, E. Bier, and R. Derynck Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands Dev. Dyn. 233 2005 1315 1331 (Pubitemid 40995129)
-
(2005)
Developmental Dynamics
, vol.233
, Issue.4
, pp. 1315-1331
-
-
Nakagawa, T.1
Guichard, A.2
Castro, C.P.3
Xiao, Y.4
Rizen, M.5
Zhang, H.-Z.6
Hu, D.7
Bang, A.8
Helms, J.9
Bier, E.10
Derynck, R.11
-
76
-
-
0030041781
-
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast
-
M. Knop, A. Finger, T. Braun, K. Hellmuth, and D.H. Wolf Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast EMBO J. 15 1996 753 763 (Pubitemid 26064282)
-
(1996)
EMBO Journal
, vol.15
, Issue.4
, pp. 753-763
-
-
Knop, M.1
Finger, A.2
Braun, T.3
Hellmuth, K.4
Wolf, D.H.5
-
77
-
-
0031885043
-
Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins
-
J. Bordallo, R.K. Plemper, A. Finger, and D.H. Wolf Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins Mol. Biol. Cell 9 1998 209 222 (Pubitemid 28065291)
-
(1998)
Molecular Biology of the Cell
, vol.9
, Issue.1
, pp. 209-222
-
-
Bordallo, J.1
Plemper, R.K.2
Finger, A.3
Wolf, D.H.4
-
78
-
-
33746228127
-
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins
-
DOI 10.1016/j.cell.2006.05.043, PII S0092867406008579
-
P. Carvalho, V. Goder, and T.A. Rapoport Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins Cell 126 2006 361 373 (Pubitemid 44092963)
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 361-373
-
-
Carvalho, P.1
Goder, V.2
Rapoport, T.A.3
-
79
-
-
3042616595
-
A membrane protein required for dislocation of misfolded proteins from the ER
-
DOI 10.1038/nature02592
-
B.N. Lilley, and H.L. Ploegh A membrane protein required for dislocation of misfolded proteins from the ER Nature 429 2004 834 840 (Pubitemid 38843291)
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 834-840
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
80
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
DOI 10.1038/nature02656
-
Y. Ye, Y. Shibata, C. Yun, D. Ron, and T.A. Rapoport A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol Nature 429 2004 841 847 (Pubitemid 38843292)
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 841-847
-
-
Ye, Y.1
Shibata, Y.2
Yun, C.3
Ron, D.4
Rapoport, T.A.5
-
81
-
-
33746675669
-
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
-
DOI 10.1016/j.cell.2006.06.041, PII S0092867406009081
-
J.M. Younger, L. Chen, H.Y. Ren, M.F. Rosser, E.L. Turnbull, C.Y. Fan, C. Patterson, and D.M. Cyr Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator Cell 126 2006 571 582 (Pubitemid 44163603)
-
(2006)
Cell
, vol.126
, Issue.3
, pp. 571-582
-
-
Younger, J.M.1
Chen, L.2
Ren, H.-Y.3
Rosser, M.F.N.4
Turnbull, E.L.5
Fan, C.-Y.6
Patterson, C.7
Cyr, D.M.8
-
82
-
-
84255169603
-
Defining human ERAD networks through an integrative mapping strategy
-
J.C. Christianson, J.A. Olzmann, T.A. Shaler, M.E. Sowa, E.J. Bennett, C.M. Richter, R.E. Tyler, E.J. Greenblatt, J. Wade Harper, and R.R. Kopito Defining human ERAD networks through an integrative mapping strategy Nat. Cell Biol. 14 2011 93 105
-
(2011)
Nat. Cell Biol.
, vol.14
, pp. 93-105
-
-
Christianson, J.C.1
Olzmann, J.A.2
Shaler, T.A.3
Sowa, M.E.4
Bennett, E.J.5
Richter, C.M.6
Tyler, R.E.7
Greenblatt, E.J.8
Wade Harper, J.9
Kopito, R.R.10
-
83
-
-
44649096231
-
BAP31 Interacts with Sec61 Translocons and Promotes Retrotranslocation of CFTRdeltaF508 via the Derlin-1 Complex
-
DOI 10.1016/j.cell.2008.04.042, PII S0092867408006168
-
B. Wang, H. Heath-Engel, D. Zhang, N. Nguyen, D.Y. Thomas, J.W. Hanrahan, and G.C. Shore BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex Cell 133 2008 1080 1092 (Pubitemid 351787744)
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1080-1092
-
-
Wang, B.1
Heath-Engel, H.2
Zhang, D.3
Nguyen, N.4
Thomas, D.Y.5
Hanrahan, J.W.6
Shore, G.C.7
-
84
-
-
31944450850
-
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
-
DOI 10.1083/jcb.200507057
-
Y. Oda, T. Okada, H. Yoshida, R.J. Kaufman, K. Nagata, and K. Mori Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation J. Cell Biol. 172 2006 383 393 (Pubitemid 43187935)
-
(2006)
Journal of Cell Biology
, vol.172
, Issue.3
, pp. 383-393
-
-
Oda, Y.1
Okada, T.2
Yoshida, H.3
Kaufman, R.J.4
Nagata, K.5
Mori, K.6
-
85
-
-
84872840929
-
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
-
J.A. Olzmann, C.M. Richter, and R.R. Kopito Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover Proc. Natl. Acad. Sci. USA 110 2013 1345 1350
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 1345-1350
-
-
Olzmann, J.A.1
Richter, C.M.2
Kopito, R.R.3
-
86
-
-
84875988193
-
Dynamics of the rhomboid-like Rhbdd2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa
-
N.B. Ahmedli, Y. Gribanova, C.C. Njoku, A. Naidu, A. Young, E. Mendoza, C.K. Yamashita, R.K. Ozgul, J.E. Johnson, D.A. Fox, and D.B. Farber Dynamics of the rhomboid-like Rhbdd2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa J. Biol. Chem. 2013
-
(2013)
J. Biol. Chem.
-
-
Ahmedli, N.B.1
Gribanova, Y.2
Njoku, C.C.3
Naidu, A.4
Young, A.5
Mendoza, E.6
Yamashita, C.K.7
Ozgul, R.K.8
Johnson, J.E.9
Fox, D.A.10
Farber, D.B.11
-
87
-
-
34548676616
-
Breast cancer molecular signatures as determined by SAGE: Correlation with lymph node status
-
DOI 10.1158/1541-7786.MCR-07-0055
-
M.C. Abba, H. Sun, K.A. Hawkins, J.A. Drake, Y. Hu, M.I. Nunez, S. Gaddis, T. Shi, S. Horvath, A. Sahin, and C.M. Aldaz Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status Mol. Cancer Res. 5 2007 881 890 (Pubitemid 47416665)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.9
, pp. 881-890
-
-
Abba, M.C.1
Sun, H.2
Hawkins, K.A.3
Drake, J.A.4
Hu, Y.5
Nunez, M.I.6
Gaddis, S.7
Shi, T.8
Horvath, S.9
Sahin, A.10
Aldaz, C.M.11
-
88
-
-
70349270573
-
Rhomboid domain containing 2 (RHBDD2): A novel cancer-related gene over-expressed in breast cancer
-
M.C. Abba, E. Lacunza, M.I. Nunez, A. Colussi, M. Isla-Larrain, A. Segal-Eiras, M.V. Croce, and C.M. Aldaz Rhomboid domain containing 2 (RHBDD2): a novel cancer-related gene over-expressed in breast cancer Biochim. Biophys. Acta 1792 2009 988 997
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 988-997
-
-
Abba, M.C.1
Lacunza, E.2
Nunez, M.I.3
Colussi, A.4
Isla-Larrain, M.5
Segal-Eiras, A.6
Croce, M.V.7
Aldaz, C.M.8
-
89
-
-
85027948998
-
RHBDD2: A 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer
-
E. Lacunza, R. Canzoneri, M.E. Rabassa, A. Zwenger, A. Segal-Eiras, M.V. Croce, and M.C. Abba RHBDD2: a 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer Tumour Biol. 33 2012 2393 2399
-
(2012)
Tumour Biol.
, vol.33
, pp. 2393-2399
-
-
Lacunza, E.1
Canzoneri, R.2
Rabassa, M.E.3
Zwenger, A.4
Segal-Eiras, A.5
Croce, M.V.6
Abba, M.C.7
-
90
-
-
79954613090
-
Monocyclic beta-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases
-
O.A. Pierrat, K. Strisovsky, Y. Christova, J. Large, K. Ansell, N. Bouloc, E. Smiljanic, and M. Freeman Monocyclic beta-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases ACS Chem. Biol. 6 2011 325 335
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 325-335
-
-
Pierrat, O.A.1
Strisovsky, K.2
Christova, Y.3
Large, J.4
Ansell, K.5
Bouloc, N.6
Smiljanic, E.7
Freeman, M.8
-
91
-
-
33745685054
-
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling
-
S. Cipolat, T. Rudka, D. Hartmann, V. Costa, L. Serneels, K. Craessaerts, K. Metzger, C. Frezza, W. Annaert, L. D'Adamio, C. Derks, T. Dejaegere, L. Pellegrini, R. D'Hooge, L. Scorrano, and B. De Strooper Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling Cell 126 2006 163 175
-
(2006)
Cell
, vol.126
, pp. 163-175
-
-
Cipolat, S.1
Rudka, T.2
Hartmann, D.3
Costa, V.4
Serneels, L.5
Craessaerts, K.6
Metzger, K.7
Frezza, C.8
Annaert, W.9
D'Adamio, L.10
Derks, C.11
Dejaegere, T.12
Pellegrini, L.13
D'Hooge, R.14
Scorrano, L.15
De Strooper, B.16
-
92
-
-
40449124712
-
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons
-
DOI 10.1038/nature06604, PII NATURE06604
-
J.R. Chao, E. Parganas, K. Boyd, C.Y. Hong, J.T. Opferman, and J.N. Ihle Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons Nature 452 2008 98 102 (Pubitemid 351355088)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 98-102
-
-
Chao, J.-R.1
Parganas, E.2
Boyd, K.3
Hong, C.Y.4
Opferman, J.T.5
Ihle, J.N.6
-
93
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
S.M. Jin, M. Lazarou, C. Wang, L.A. Kane, D.P. Narendra, and R.J. Youle Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL J. Cell Biol. 191 2010 933 942
-
(2010)
J. Cell Biol.
, vol.191
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
Wang, C.3
Kane, L.A.4
Narendra, D.P.5
Youle, R.J.6
-
94
-
-
79551574736
-
PINK1 cleavage at position A103 by the mitochondrial protease PARL
-
E. Deas, H. Plun-Favreau, S. Gandhi, H. Desmond, S. Kjaer, S.H. Loh, A.E. Renton, R.J. Harvey, A.J. Whitworth, L.M. Martins, A.Y. Abramov, and N.W. Wood PINK1 cleavage at position A103 by the mitochondrial protease PARL Hum. Mol. Genet. 20 2011 867 879
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 867-879
-
-
Deas, E.1
Plun-Favreau, H.2
Gandhi, S.3
Desmond, H.4
Kjaer, S.5
Loh, S.H.6
Renton, A.E.7
Harvey, R.J.8
Whitworth, A.J.9
Martins, L.M.10
Abramov, A.Y.11
Wood, N.W.12
-
95
-
-
79955410000
-
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease
-
G. Shi, J.R. Lee, D.A. Grimes, L. Racacho, D. Ye, H. Yang, O.A. Ross, M. Farrer, G.A. McQuibban, and D.E. Bulman Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease Hum. Mol. Genet. 20 2011 1966 1974
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1966-1974
-
-
Shi, G.1
Lee, J.R.2
Grimes, D.A.3
Racacho, L.4
Ye, D.5
Yang, H.6
Ross, O.A.7
Farrer, M.8
McQuibban, G.A.9
Bulman, D.E.10
-
96
-
-
79955667485
-
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
-
C. Meissner, H. Lorenz, A. Weihofen, D.J. Selkoe, and M.K. Lemberg The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking J. Neurochem. 117 2011 856 867
-
(2011)
J. Neurochem.
, vol.117
, pp. 856-867
-
-
Meissner, C.1
Lorenz, H.2
Weihofen, A.3
Selkoe, D.J.4
Lemberg, M.K.5
-
97
-
-
84867257217
-
Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5
-
S. Sekine, Y. Kanamaru, M. Koike, A. Nishihara, M. Okada, H. Kinoshita, M. Kamiyama, J. Maruyama, Y. Uchiyama, N. Ishihara, K. Takeda, and H. Ichijo Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5 J. Biol. Chem. 287 2012 34635 34645
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34635-34645
-
-
Sekine, S.1
Kanamaru, Y.2
Koike, M.3
Nishihara, A.4
Okada, M.5
Kinoshita, H.6
Kamiyama, M.7
Maruyama, J.8
Uchiyama, Y.9
Ishihara, N.10
Takeda, K.11
Ichijo, H.12
|