-
1
-
-
57149083070
-
A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus
-
Willger SD, Puttikamonkul S, Kim K-H, Burritt JB, Grahl N, Metzler LJ, Barbuch R, Bard M, Lawrence CB, Cramer RA, Jr. 2008. A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. PLoS Pathog 4:e1000200. http://dx.doi.org/10.1371/ journal.ppat.1000200
-
(2008)
PLoS Pathog
, vol.4
-
-
Willger, S.D.1
Puttikamonkul, S.2
Kim, K.-H.3
Burritt, J.B.4
Grahl, N.5
Metzler, L.J.6
Barbuch, R.7
Bard, M.8
Lawrence, C.B.9
Cramer, R.A.10
-
2
-
-
34247547435
-
Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans
-
Chang YC, Bien CM, Lee H, Espenshade PJ, Kwon-Chung KJ. 2007. Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans. Mol Microbiol 64:614-629. http://dx.doi.org/10.1111/j.1365-2958.2007.05676.x
-
(2007)
Mol Microbiol
, vol.64
, pp. 614-629
-
-
Chang, Y.C.1
Bien, C.M.2
Lee, H.3
Espenshade, P.J.4
Kwon-Chung, K.J.5
-
3
-
-
33847335459
-
A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans
-
Chun CD, Liu OW, Madhani HD. 2007. A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans. PLoS Pathog 3:e22. http:// dx.doi.org/10.1371/journal.ppat.0030022
-
(2007)
PLoS Pathog
, vol.3
, pp. e22
-
-
Chun, C.D.1
Liu, O.W.2
Madhani, H.D.3
-
4
-
-
84855278233
-
SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus
-
Blatzer M, Barker BM, Willger SD, Beckmann N, Blosser SJ, Cornish EJ, Mazurie A, Grahl N, Haas H, Cramer RA. 2011. SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus. PLoS Genet 7:e1002374. http://dx.doi.org/10.1371/journal.pgen.1002374
-
(2011)
PLoS Genet
, vol.7
-
-
Blatzer, M.1
Barker, B.M.2
Willger, S.D.3
Beckmann, N.4
Blosser, S.J.5
Cornish, E.J.6
Mazurie, A.7
Grahl, N.8
Haas, H.9
Cramer, R.A.10
-
5
-
-
84912121231
-
ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence
-
Chung D, Barker BM, Carey CC, Merriman B, Werner ER, Lechner BE, Dhingra S, Cheng C, Xu W, Blosser SJ, Morohashi K, Mazurie A, Mitchell TK, Haas H, Mitchell AP, Cramer RA. 2014. ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence. PLoS Pathog 10:e1004487. http://dx.doi.org/10.1371/ journal.ppat.1004487
-
(2014)
PLoS Pathog
, vol.10
-
-
Chung, D.1
Barker, B.M.2
Carey, C.C.3
Merriman, B.4
Werner, E.R.5
Lechner, B.E.6
Dhingra, S.7
Cheng, C.8
Xu, W.9
Blosser, S.J.10
Morohashi, K.11
Mazurie, A.12
Mitchell, T.K.13
Haas, H.14
Mitchell, A.P.15
Cramer, R.A.16
-
6
-
-
17644401005
-
SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast
-
Hughes AL, Todd BL, Espenshade PJ. 2005. SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell 120:831-842. http://dx.doi.org/10.1016/j.cell.2005.01.012
-
(2005)
Cell
, vol.120
, pp. 831-842
-
-
Hughes, A.L.1
Todd, B.L.2
Espenshade, P.J.3
-
7
-
-
79954525510
-
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex
-
Stewart EV, Nwosu CC, Tong Z, Roguev A, Cummins TD, Kim D-U, Hayles J, Park H-O, Hoe K-L, Powell DW, Krogan NJ, Espenshade PJ. 2011. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Mol Cell 42:160-171. http://dx.doi.org/10.1016/ j.molcel.2011.02.035
-
(2011)
Mol Cell
, vol.42
, pp. 160-171
-
-
Stewart, E.V.1
Nwosu, C.C.2
Tong, Z.3
Roguev, A.4
Cummins, T.D.5
Kim, D.-U.6
Hayles, J.7
Park, H.-O.8
Hoe, K.-L.9
Powell, D.W.10
Krogan, N.J.11
Espenshade, P.J.12
-
8
-
-
44349091967
-
Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member
-
Hughes BT, Espenshade PJ. 2008. Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member. EMBO J 27:1491-1501. http://dx.doi.org/10.1038/emboj.2008.83
-
(2008)
EMBO J
, vol.27
, pp. 1491-1501
-
-
Hughes, B.T.1
Espenshade, P.J.2
-
9
-
-
58749108297
-
Oxygendependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast
-
Lee CY, Stewart EV, Hughes BT, Espenshade PJ. 2009. Oxygendependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast. EMBO J 28:135-143. http://dx.doi.org/ 10.1038/emboj.2008.271
-
(2009)
EMBO J
, vol.28
, pp. 135-143
-
-
Lee, C.Y.1
Stewart, E.V.2
Hughes, B.T.3
Espenshade, P.J.4
-
10
-
-
0030941803
-
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown MS, Goldstein JL. 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340. http://dx.doi.org/10.1016/S0092-8674(00)80213-5
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
11
-
-
70350397502
-
Cryptococcus neoformans site-2 protease is required for virulence and survival in the presence of azole drugs
-
Bien CM, Chang YC, Nes WD, Kwon-Chung KJ, Espenshade PJ. 2009. Cryptococcus neoformans site-2 protease is required for virulence and survival in the presence of azole drugs. Mol Microbiol 74:672-690. http://dx.doi.org/10.1111/j.1365-2958.2009.06895.x
-
(2009)
Mol Microbiol
, vol.74
, pp. 672-690
-
-
Bien, C.M.1
Chang, Y.C.2
Nes, W.D.3
Kwon-Chung, K.J.4
Espenshade, P.J.5
-
12
-
-
84870421349
-
Dsc orthologs are required for hypoxia adaptation, triazole drug responses, and fungal virulence in Aspergillus fumigatus
-
Willger SD, Cornish EJ, Chung D, Fleming BA, Lehmann MM, Puttikamonkul S, Cramer RA. 2012. Dsc orthologs are required for hypoxia adaptation, triazole drug responses, and fungal virulence in Aspergillus fumigatus. Eukaryot Cell 11:1557-1567. http://dx.doi.org/10.1128/ EC.00252-12
-
(2012)
Eukaryot Cell
, vol.11
, pp. 1557-1567
-
-
Willger, S.D.1
Cornish, E.J.2
Chung, D.3
Fleming, B.A.4
Lehmann, M.M.5
Puttikamonkul, S.6
Cramer, R.A.7
-
13
-
-
84949624401
-
Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast
-
Kim J, Ha H-J, Kim S, Choi A-R, Lee S-J, Hoe K-L, Kim D-U. 2015. Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast. Biochem Biophys Res Commun 468:606-610. http://dx.doi.org/10.1016/ j.bbrc.2015.10.165
-
(2015)
Biochem Biophys Res Commun
, vol.468
, pp. 606-610
-
-
Kim, J.1
Ha, H.-J.2
Kim, S.3
Choi, A.-R.4
Lee, S.-J.5
Hoe, K.-L.6
Kim, D.-U.7
-
14
-
-
0017447640
-
Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations
-
Käfer E. 1977. Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Adv Genet 19:33-131. http://dx.doi.org/ 10.1016/S0065-2660(08)60245-X
-
(1977)
Adv Genet
, vol.19
, pp. 33-131
-
-
Käfer, E.1
-
15
-
-
84455170096
-
SREBP-dependent triazole susceptibility in Aspergillus fumigatus is mediated through direct transcriptional regulation of erg11A (cyp51A)
-
Blosser SJ, Cramer RA. 2012. SREBP-dependent triazole susceptibility in Aspergillus fumigatus is mediated through direct transcriptional regulation of erg11A (cyp51A). Antimicrob Agents Chemother 56:248-257. http://dx.doi.org/10.1128/AAC.05027-11
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 248-257
-
-
Blosser, S.J.1
Cramer, R.A.2
-
16
-
-
78149308102
-
HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus
-
Schrettl M, Beckmann N, Varga J, Heinekamp T, Jacobsen ID, Jöchl C, Moussa TA, Wang S, Gsaller F, Blatzer M, Werner ER, Niermann WC, Brakhage AA, Haas H. 2010. HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus. PLoS Pathog 6:e1001124. http://dx.doi.org/10.1371/journal.ppat.1001124
-
(2010)
PLoS Pathog
, vol.6
-
-
Schrettl, M.1
Beckmann, N.2
Varga, J.3
Heinekamp, T.4
Jacobsen, I.D.5
Jöchl, C.6
Moussa, T.A.7
Wang, S.8
Gsaller, F.9
Blatzer, M.10
Werner, E.R.11
Niermann, W.C.12
Brakhage, A.A.13
Haas, H.14
-
17
-
-
80051799474
-
Iron homeostasis-Achilles' heel of Aspergillus fumigatus?
-
Schrettl M, Haas H. 2011. Iron homeostasis-Achilles' heel of Aspergillus fumigatus? Curr Opin Microbiol 14:400-405. http://dx.doi.org/10.1016/ j.mib.2011.06.002
-
(2011)
Curr Opin Microbiol
, vol.14
, pp. 400-405
-
-
Schrettl, M.1
Haas, H.2
-
18
-
-
79960941562
-
In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis
-
Grahl N, Puttikamonkul S, Macdonald JM, Gamcsik MP, Ngo LY, Hohl TM, Cramer RA. 2011. In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis. PLoS Pathog 7:e1002145. http://dx.doi.org/10.1371/ journal.ppat.1002145
-
(2011)
PLoS Pathog
, vol.7
-
-
Grahl, N.1
Puttikamonkul, S.2
Macdonald, J.M.3
Gamcsik, M.P.4
Ngo, L.Y.5
Hohl, T.M.6
Cramer, R.A.7
-
19
-
-
0033613147
-
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
-
Brown MS, Goldstein JL. 1999. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc Natl Acad Sci U S A 96:11041-11048. http://dx.doi.org/10.1073/pnas.96.20.11041
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11041-11048
-
-
Brown, M.S.1
Goldstein, J.L.2
-
20
-
-
33751246749
-
Rhomboid proteins: conserved membrane proteases with divergent biological functions
-
Urban S. 2006. Rhomboid proteins: conserved membrane proteases with divergent biological functions. Genes Dev 20:3054-3068. http:// dx.doi.org/10.1101/gad.1488606
-
(2006)
Genes Dev
, vol.20
, pp. 3054-3068
-
-
Urban, S.1
-
21
-
-
84959508424
-
The signal peptide peptidase SppA is involved in sterol regulatory element-binding protein cleavage and hypoxia adaptation in Aspergillus nidulans
-
29 January
-
Bat-Ochir C, Kwak J-Y, Koh S-K, Jeon M-H, Chung D, Lee Y-W, Chae S-K. 29 January 2016. The signal peptide peptidase SppA is involved in sterol regulatory element-binding protein cleavage and hypoxia adaptation in Aspergillus nidulans. Mol Microbiol. http://dx.doi.org/10.1111/ mmi.13341
-
(2016)
Mol Microbiol
-
-
Bat-Ochir, C.1
Kwak, J.-Y.2
Koh, S.-K.3
Jeon, M.-H.4
Chung, D.5
Lee, Y.-W.6
Chae, S.-K.7
-
22
-
-
0036777494
-
Intramembrane proteolysis controls diverse signalling pathways throughout evolution
-
Urban S, Freeman M. 2002. Intramembrane proteolysis controls diverse signalling pathways throughout evolution. Curr Opin Genet Dev 12: 512-518. http://dx.doi.org/10.1016/S0959-437X(02)00334-9
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 512-518
-
-
Urban, S.1
Freeman, M.2
-
23
-
-
0037102238
-
A family of rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands
-
Urban S, Lee JR, Freeman M. 2002. A family of rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands. EMBO J 21:4277-4286. http://dx.doi.org/10.1093/emboj/cdf434
-
(2002)
EMBO J
, vol.21
, pp. 4277-4286
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
24
-
-
0001963674
-
A convenient growth medium for Neurospora (medium N)
-
Vogel H. 1956. A convenient growth medium for Neurospora (medium N). Microb Genet Bull 13:2-43
-
(1956)
Microb Genet Bull
, vol.13
, pp. 2-43
-
-
Vogel, H.1
-
25
-
-
0041472360
-
The Fungal Genetics Stock Center: from molds to molecules
-
McCluskey K. 2003. The Fungal Genetics Stock Center: from molds to molecules. Adv Appl Microbiol 52:245-262. http://dx.doi.org/10.1016/ S0065-2164(03)01010-4
-
(2003)
Adv Appl Microbiol
, vol.52
, pp. 245-262
-
-
McCluskey, K.1
-
26
-
-
84885051447
-
The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus
-
Dhingra S, Lind AL, Lin H-C, Tang Y, Rokas A, Calvo AM. 2013. The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus. PLoS One 8:e77147. http://dx.doi.org/ 10.1371/journal.pone.0077147
-
(2013)
PLoS One
, vol.8
-
-
Dhingra, S.1
Lind, A.L.2
Lin, H.-C.3
Tang, Y.4
Rokas, A.5
Calvo, A.M.6
-
27
-
-
34248562159
-
Fusion PCR and gene targeting in Aspergillus nidulans
-
Szewczyk E, Nayak T, Oakley CE, Edgerton H, Xiong Y, Taheri-Talesh N, Osmani SA, Oakley BR. 2006. Fusion PCR and gene targeting in Aspergillus nidulans. Nat Protoc 1:3111-3120. http://dx.doi.org/10.1038/ nprot.2006.405
-
(2006)
Nat Protoc
, vol.1
, pp. 3111-3120
-
-
Szewczyk, E.1
Nayak, T.2
Oakley, C.E.3
Edgerton, H.4
Xiong, Y.5
Taheri-Talesh, N.6
Osmani, S.A.7
Oakley, B.R.8
-
28
-
-
84901989785
-
Endoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus
-
Chung D, Thammahong A, Shepardson KM, Blosser SJ, Cramer RA. 2014. Endoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus. Mol Microbiol 92:1279-1298. http://dx.doi.org/10.1111/mmi.12626
-
(2014)
Mol Microbiol
, vol.92
, pp. 1279-1298
-
-
Chung, D.1
Thammahong, A.2
Shepardson, K.M.3
Blosser, S.J.4
Cramer, R.A.5
-
29
-
-
67249090804
-
Screening method to identify inhibitors of siderophore biosynthesis in the opportunistic fungal pathogen, Aspergillus fumigatus
-
Pinto LJ, Moore MM. 2009. Screening method to identify inhibitors of siderophore biosynthesis in the opportunistic fungal pathogen, Aspergillus fumigatus. Lett Appl Microbiol 49:8-13. http://dx.doi.org/10.1111/ j.1472-765X.2009.02582.x
-
(2009)
Lett Appl Microbiol
, vol.49
, pp. 8-13
-
-
Pinto, L.J.1
Moore, M.M.2
|